Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC131885 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC217176 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 POLB 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 AKR1B1 1 22900 IC50 PMID: 20805028
NPC247553 CASP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 CASP7 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 MAPT 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC257188 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 CA12 1 25700 Ki PMID: 22892213
NPC257188 CA1 1 21500 Ki PMID: 22892213
NPC257188 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC265547 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC265547 ALDH1A1 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC265547 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC265547 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC266743 HTT 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 BLM 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 PLEC 2 Median: 93960.05
Range: 32104.8 to 155815.3
IC50 PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288089 ALDH1A1 2 Median: 33997.25
Range: 28183.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288089 THRB 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 CASP7 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 PTPN7 1 19620 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC288089 BCHE 1 17000 IC50 PMID: 24568372
NPC288089 CASP1 5 Median: 25118.9
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288089 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288089 ALOX12 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC307412 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC307412 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC307412 HPGD 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC33320 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 ALDH1A1 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 TP53 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 CYP2D6 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51146 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51146 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51146 HSD17B10 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51146 MAOA 1 21300 IC50 PMID: 23517722
NPC5167 ALDH1A1 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC74539 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC74539 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC74539 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC88445 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC88445 LMNA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 KDM4E 2 Median: 21154.6
Range: 14125.4 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288089 HSD17B10 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC288089 LMNA 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC288089 POLB 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC33320 CYP3A4 4 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 HPGD 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 KDM4E 2 Median: 13357.35
Range: 12589.3 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC5167 KDM4E 2 Median: 22106.05
Range: 12589.3 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC5167 HSD17B10 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC5167 HPGD 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC74539 MAOA 1 13800 IC50 PMID: 23517722
NPC74539 CYP2A6 1 12000 Ki PMID: 16248836