Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC100551 | CA14 | 1 | 49800 | Ki |
PMID: 18579385 |
| NPC100551 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | HPGD | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC110899 | CA5B | 1 | 35400 | Ki |
PMID: 20185318 |
| NPC131718 | ALDH1A1 | 1 | 39810.7 | Potency |
Open TG-GATES CHEMBL3885861 |
| NPC156461 | GAPDH | 7 |
Median: 35000000 Range: 35000 to 100000000 |
IC50 |
PMID: 7562915 PMID: 7562915 PMID: 7562915 PMID: 7932587 PMID: 7932587 PMID: 7932587 PMID: 9822549 |
| NPC156461 | ADORA2B | 3 |
Median: 24000 Range: 24000 to 24000 |
EC50 |
PMID: 20541935 PMID: 21388809 PMID: 24164628 |
| NPC156461 | SLC29A1 | 1 | 17000 | IC50 |
PMID: 23388705 |
| NPC164664 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18188 | SLC6A12 | 1 | 36000 | IC50 |
PMID: 8057281 |
| NPC18188 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18188 | TSHR | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18188 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18188 | THRB | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | TSHR | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | MAPT | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC207428 | TDP1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC207428 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC207428 | L3MBTL1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC207428 | HSD17B10 | 2 |
Median: 28370.85 Range: 25118.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC207428 | BCHE | 1 | 25100 | IC50 |
PMID: 18524585 |
| NPC207554 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC207554 | MAPT | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209389 | SRC | 1 | 28000 | IC50 |
PMID: 12672248 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC254698 | MAOA | 3 |
Median: 40000 Range: 31800 to 56234.13 |
IC50 |
PMID: 20715818 PMID: 20934874 PMID: 21134756 |
| NPC254698 | MAOB | 7 |
Median: 18750 Range: 18750 to 18750 |
IC50 |
PMID: 19926363 PMID: 20615716 PMID: 20715818 PMID: 21872365 PMID: 23153812 PMID: 24746464 DOI: 10.1039/C0MD00014K |
| NPC255607 | OPRM1 | 1 | 32500 | EC50 |
PMID: 17616524 |
| NPC257582 | CYP3A4 | 1 | 25600 | IC50 |
PMID: 21138310 |
| NPC288349 | ATM | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC295021 | NQO1 | 1 | 25000 | IC50 |
PMID: 17011189 |
| NPC300596 | MAPK1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC300596 | SMN1;SMN2 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC300596 | SRC | 1 | 18000 | IC50 |
PMID: 12672248 |
| NPC302950 | ATM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | CYP1A2 | 1 | 34647 | IC50 |
PMID: 20696580 |
| NPC302950 | GSK3B | 1 | 26900 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC302950 | TP53 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC42372 | IMPDH2 | 1 | 22700 | IC50 |
PMID: 16483769 |
| NPC50511 | ALOX15 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC100551 | CA6 | 2 |
Median: 1165950 Range: 11900 to 2320000 |
Ki |
PMID: 18579385 PMID: 21669522 |
| NPC100551 | CA4 | 1 | 11100 | Ki |
PMID: 18579385 |
| NPC110899 | CA4 | 1 | 10600 | Ki |
PMID: 20185318 |
| NPC156461 | MAPK1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC207554 | HTT | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | HSD17B10 | 2 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50511 | TP53 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50511 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |