Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC127447 TSHR 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 BLM 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 CYP19A1 1 32700 IC50 PMID: 16643058
NPC261831 TOP1 1 31000 IC50 PMID: 12444712
NPC261831 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 FABP4 1 26100 IC50 PMID: 20471252
NPC261831 KMT2A 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 ATM 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 HSD17B10 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC78540 CALM1;CALM2;CALM3 1 33430 IC50 PMID: 21129983
NPC78540 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78540 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78540 PTGS2 1 25500 IC50 PMID: 24332492
NPC78540 TP53 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC84319 PYGM 1 28000 IC50 PMID: 16169219
NPC84319 PTPN2 1 19470 IC50 PMID: 19846303
NPC85813 CYP19A1 1 48000 IC50 PMID: 16643058
NPC85813 F3 1 41000 IC50 PMID: 9834151
NPC85813 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94045 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94045 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC94045 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94045 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94045 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94045 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94045 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC94045 MAPT 2 Median: 24068.2
Range: 19952.6 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC94045 TRPV1 3 Median: 23700
Range: 15000 to 30000
IC50 PMID: 26750258
PMID: 26750258
PMID: 26750258
NPC261831 KCNH2 1 10410 EC50 PubChem BioAssay data set
CHEMBL1201862
NPC78540 CYP2D6 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC85813 FABP4 2 Median: 15650
Range: 13600 to 17700
IC50 PMID: 20471252
PMID: 25461324
NPC85813 PTGS1 1 13000 IC50 PMID: 16038536