Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC101475 | AKR1B10 | 1 | 30000 | IC50 |
PMID: 21561086 |
| NPC142415 | ACP1 | 4 |
Median: 22050 Range: 21200 to 22900 |
IC50 |
PMID: 21453996 PMID: 21453996 PMID: 25264584 PMID: 25264584 |
| NPC142415 | PTPN6 | 2 |
Median: 22760 Range: 14190 to 31330 |
IC50 |
PMID: 18707891 PMID: 27123900 |
| NPC144939 | CYP3A4 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC144939 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC279121 | GALK1 | 1 | 47269 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | TSHR | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2C9 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | GAA | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | DAPK1 | 1 | 21000 | IC50 |
PMID: 26322379 |
| NPC279121 | CDK2 | 1 | 20000 | IC50 |
PMID: 17178224 |
| NPC279121 | TDP1 | 2 |
Median: 29881.65 Range: 19952.6 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | ABCB1 | 1 | 19600 | IC50 |
PMID: 15240100 |
| NPC279121 | GPR35 | 1 | 18600 | IC50 |
PMID: 24900447 |
| NPC279121 | AMY1A;AMY1B;AMY1C | 1 | 18400 | IC50 |
PMID: 18507367 |
| NPC279121 | MMP3 | 1 | 16200 | IC50 |
PMID: 22658537 |
| NPC279121 | CYP2C19 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | BLM | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC289774 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | KDM4E | 3 |
Median: 35481.3 Range: 28183.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | MAPK1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC300326 | PTGS1 | 1 | 39200 | IC50 |
PMID: 22386242 |
| NPC300326 | PTGS2 | 1 | 28000 | IC50 |
PMID: 22386242 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC84319 | PYGM | 1 | 28000 | IC50 |
PMID: 16169219 |
| NPC84319 | PTPN2 | 1 | 19470 | IC50 |
PMID: 19846303 |
| NPC12278 | ALOX5 | 1 | 13000 | IC50 |
PMID: 24568174 |
| NPC142415 | PTPRF | 2 |
Median: 17055 Range: 11800 to 22310 |
IC50 |
PMID: 21453996 PMID: 27123900 |
| NPC142415 | PTPN11 | 1 | 11620 | IC50 |
PMID: 27123900 |
| NPC156018 | SMN1;SMN2 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | MAPT | 3 |
Median: 12589.3 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | SYK | 1 | 12000 | IC50 |
PMID: 22257213 |
| NPC279121 | HPGD | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | MMP13 | 1 | 10050 | IC50 |
PMID: 22658537 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |