Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC179787 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179787 | TSHR | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC179787 | ALDH1A1 | 5 |
Median: 28183.8 Range: 25118.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC179787 | KDM4E | 4 |
Median: 29903.3 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC179787 | BLM | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179787 | HSD17B10 | 4 |
Median: 25118.9 Range: 15848.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC2518 | ATM | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC2518 | THRB | 2 |
Median: 34893.65 Range: 25118.9 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | CYP19A1 | 1 | 32700 | IC50 |
PMID: 16643058 |
| NPC261831 | TOP1 | 1 | 31000 | IC50 |
PMID: 12444712 |
| NPC261831 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | FABP4 | 1 | 26100 | IC50 |
PMID: 20471252 |
| NPC261831 | KMT2A | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | ATM | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | HSD17B10 | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC289004 | ATM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC292792 | PPARA | 1 | 46500 | EC50 |
PMID: 22381047 |
| NPC292792 | PPARG | 1 | 40000 | EC50 |
PMID: 22381047 |
| NPC292792 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | KDM4E | 3 |
Median: 35481.3 Range: 28183.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | MAPK1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294941 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC300326 | PTGS1 | 1 | 39200 | IC50 |
PMID: 22386242 |
| NPC300326 | PTGS2 | 1 | 28000 | IC50 |
PMID: 22386242 |
| NPC310373 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC310373 | HPGD | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC310373 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC310373 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC474148 | SLC6A2 | 1 | 30000 | IC50 |
Open TG-GATES CHEMBL3885861 |
| NPC63545 | HPGD | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC63545 | ALDH1A1 | 2 |
Median: 33552.05 Range: 31622.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC63545 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC63545 | AURKA | 1 | 15848.93 | Ki |
PubChem BioAssay data set CHEMBL1201862 |
| NPC63545 | CHUK | 1 | 15000 | IC50 |
PMID: 12824047 |
| NPC71853 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | ALOX15 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC8235 | TDP1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
| NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
| NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC92114 | TERT | 1 | 15000 | IC50 |
DOI: 10.1039/C0MD00241K |
| NPC179787 | HPGD | 5 |
Median: 28183.8 Range: 12589.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | KCNH2 | 1 | 10410 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | ALOX12 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
| NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |