Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC126681 | SLC6A9 | 1 | 31600 | IC50 |
PMID: 24461352 |
| NPC137958 | CYP1A2 | 1 | 39810.72 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137958 | SLC1A3 | 1 | 35000 | Ki |
PMID: 18578477 |
| NPC167400 | ALDH1A1 | 1 | 18029.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC187770 | TYR | 1 | 32500 | IC50 |
PMID: 25726329 |
| NPC208793 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC208793 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC208793 | CYP2C19 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC226453 | APEX1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC226453 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC306397 | SIRT5 | 1 | 46600 | IC50 |
PMID: 24900427 |
| NPC306397 | SIRT1 | 7 |
Median: 73000 Range: 25000 to 149000 |
IC50 |
PMID: 19700324 PMID: 23318905 PMID: 24900427 PMID: 25275824 PMID: 25549554 PMID: 26696402 DOI: 10.1039/C1MD00199J |
| NPC55412 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC55412 | ALDH1A1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC55412 | MAPT | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC55412 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | CASP7 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | CASP1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | CYP3A4 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | HSD17B10 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC226265 | LMNA | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC55412 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94167 | HPGD | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |