Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC100980 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC117237 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC117237 | AOX1 | 1 | 15000 | IC50 |
PMID: 20853847 |
| NPC131885 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC131885 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC131885 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | ALDH1A1 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HPGD | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | CYP1A2 | 1 | 15848.93 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GLA | 2 |
Median: 15954.1 Range: 14125.4 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | RAD52 | 1 | 15210 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC16107 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC202605 | CYP3A4 | 1 | 30600 | IC50 |
PMID: 17994701 |
| NPC202768 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | HPGD | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | ALDH1A1 | 2 |
Median: 31832.55 Range: 28183.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | HSD17B10 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | BLM | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | MTOR | 1 | 18492.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | HIF1A | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC226143 | MAPT | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC226143 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC226143 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC261831 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | CYP19A1 | 1 | 32700 | IC50 |
PMID: 16643058 |
| NPC261831 | TOP1 | 1 | 31000 | IC50 |
PMID: 12444712 |
| NPC261831 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | FABP4 | 1 | 26100 | IC50 |
PMID: 20471252 |
| NPC261831 | KMT2A | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | ATM | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | HSD17B10 | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC296482 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC296482 | BCHE | 1 | 18970 | IC50 |
PMID: 21924611 |
| NPC296482 | MAPT | 2 |
Median: 21450.85 Range: 17782.8 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC305016 | CYP3A4 | 1 | 23200 | Ki |
PMID: 16248836 |
| NPC308267 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC308267 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34770 | ALDH1A1 | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34770 | TP53 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34770 | CYP2D6 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC36229 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC36229 | MAPT | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC51957 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | ALDH1A1 | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | TERT | 1 | 37000 | IC50 |
PMID: 22336246 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77572 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC95381 | TTR | 1 | 23000 | EC50 |
PMID: 25314129 |
| NPC100980 | CA14 | 4 |
Median: 11500 Range: 11500 to 11500 |
Ki |
PMID: 20185318 PMID: 20590092 PMID: 20674354 PMID: 23010455 |
| NPC100980 | CA1 | 9 |
Median: 10200 Range: 10200 to 10200 |
Ki |
PMID: 20185318 PMID: 20590092 PMID: 20674354 PMID: 21282059 PMID: 23010455 PMID: 23265898 PMID: 24189056 PMID: 26073005 PMID: 26520662 |
| NPC137949 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HSD17B10 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | SMN1;SMN2 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC16452 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC16452 | CYP2D6 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | SMN1;SMN2 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202768 | NPSR1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC21429 | TP53 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | KCNH2 | 1 | 10410 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC296482 | CYP3A4 | 4 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC308267 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34770 | HPGD | 2 |
Median: 14125.4 Range: 14125.4 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34770 | HSD17B10 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34770 | KDM4E | 2 |
Median: 13357.35 Range: 12589.3 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC51957 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | TSHR | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC53069 | MAPT | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |