Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC116775 BCHE 1 43100 Ki PMID: 19879672
NPC116775 ALDH1A1 2 Median: 35716.75
Range: 31622.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC116775 CDK6 2 Median: 22000
Range: 22000 to 22000
IC50 PMID: 15689157
DOI: 10.1007/s00044-009-9233-5
NPC116775 GLO1 1 20600 IC50 PMID: 18258440
NPC116775 KDM4E 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HSD17B10 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 BACE1 1 14700 IC50 DOI: 10.1007/s00044-012-0353-y
NPC133671 P4HB 1 19020 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC137949 GAA 2 Median: 35481.3
Range: 35481.3 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 ALDH1A1 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 MAPT 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC137949 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC137949 GLA 2 Median: 15954.1
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC139891 TDP1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC84281 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC84281 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC116775 MAPT 2 Median: 14219.1
Range: 12589.3 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC137949 SMN1;SMN2 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178263 CYP2C9 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862