Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC110899 | CA5B | 1 | 35400 | Ki |
PMID: 20185318 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | CA14 | 2 |
Median: 48900 Range: 48900 to 48900 |
Ki |
PMID: 18579385 PMID: 20185318 |
| NPC204932 | BLM | 2 |
Median: 44668.4 Range: 44668.4 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | EGFR | 1 | 26043 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC204932 | MMP9 | 1 | 23367 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC204932 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | L3MBTL1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | FYN | 1 | 17431 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC204932 | RECQL | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | ALOX15 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | EPHX2 | 1 | 36400 | IC50 |
PMID: 26483136 |
| NPC254847 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | TP53 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | PTP4A3 | 2 |
Median: 31500 Range: 28000 to 35000 |
IC50 |
PMID: 22137788 PMID: 22137788 |
| NPC254847 | NPC1 | 1 | 20596.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261619 | BACE1 | 2 |
Median: 25500 Range: 23000 to 28000 |
IC50 |
PMID: 14592472 PMID: 14592472 |
| NPC280254 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | BRCA1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | USP2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ELANE | 1 | 18000 | IC50 |
PMID: 1578486 |
| NPC282923 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC3224 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | HPGD | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | MAPK1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | RECQL | 2 |
Median: 77689.6 Range: 14125.4 to 141253.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC110899 | CA4 | 1 | 10600 | Ki |
PMID: 20185318 |
| NPC204932 | ALDH1A1 | 2 |
Median: 15954.1 Range: 14125.4 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | CA3 | 2 |
Median: 13000 Range: 13000 to 13000 |
Ki |
PMID: 18579385 PMID: 20185318 |
| NPC204932 | SMN1;SMN2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | LMNA | 2 |
Median: 23350.75 Range: 11220.2 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | HPGD | 2 |
Median: 14501.5 Range: 11220.2 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | GMNN | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | CA4 | 3 |
Median: 10900 Range: 10900 to 10900 |
Ki |
PMID: 18579385 PMID: 20185318 PMID: 22245047 |
| NPC254847 | TDP1 | 2 |
Median: 15186.05 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | CYP2D6 | 2 |
Median: 22106.05 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | ALDH1A1 | 2 |
Median: 13357.35 Range: 12589.3 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | MAPK1 | 2 |
Median: 11904.75 Range: 11220.2 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC280254 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC312929 | HPGD | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | MAPT | 2 |
Median: 14125.4 Range: 14125.4 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | CA14 | 1 | 11550 | Ki |
PMID: 20674354 |
| NPC61477 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | CA13 | 1 | 10510 | Ki |
PMID: 20674354 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |