Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC100079 RAB9A 1 46109.1 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP2C9 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 HIF1A 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 TSHR 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP2D6 1 25118.86 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC100079 HPGD 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 HSD17B10 2 Median: 22535.75
Range: 19952.6 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 ALDH1A1 2 Median: 19118.05
Range: 15848.9 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 MAPT 4 Median: 15848.9
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110899 CA5B 1 35400 Ki PMID: 20185318
NPC131885 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131885 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC160100 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC288943 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 ALDH1A1 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 TP53 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 CYP2D6 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 GLA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 GAA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 RECQL 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA13 1 17800 Ki PMID: 22892213
NPC100079 ALOX12 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 NFKB1 2 Median: 11220.2
Range: 11220.2 to 11220.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110899 CA4 1 10600 Ki PMID: 20185318
NPC34770 HPGD 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 KDM4E 2 Median: 13357.35
Range: 12589.3 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA1 1 10560 Ki PMID: 22892213