Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC1075 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC126029 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | CA14 | 2 |
Median: 48900 Range: 48900 to 48900 |
Ki |
PMID: 18579385 PMID: 20185318 |
| NPC204932 | BLM | 2 |
Median: 44668.4 Range: 44668.4 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | EGFR | 1 | 26043 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC204932 | MMP9 | 1 | 23367 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC204932 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | L3MBTL1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | FYN | 1 | 17431 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC204932 | RECQL | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | ALOX15 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | PTGS1 | 2 |
Median: 58350 Range: 36700 to 80000 |
IC50 |
PMID: 11858749 PMID: 16038536 |
| NPC219876 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | BLM | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | RECQL | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | MAPT | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | APEX1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC261619 | BACE1 | 2 |
Median: 25500 Range: 23000 to 28000 |
IC50 |
PMID: 14592472 PMID: 14592472 |
| NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
| NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
| NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | CACNA1C | 1 | 50000 | IC50 |
PMID: 22761000 |
| NPC48342 | NR3C1 | 1 | 41422 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC48342 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | GPBAR1 | 1 | 38400 | EC50 |
PMID: 18307294 |
| NPC48342 | ALDH1A1 | 1 | 37650.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | RECQL | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | HSD17B10 | 2 |
Median: 22535.75 Range: 19952.6 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | SLC6A3 | 1 | 14911 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC61477 | HPGD | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | MAPK1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | RECQL | 2 |
Median: 77689.6 Range: 14125.4 to 141253.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115674 | XDH | 1 | 11900 | IC50 |
PMID: 9461655 |
| NPC126029 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC126029 | KDM4E | 2 |
Median: 16803.7 Range: 11220.2 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | ALDH1A1 | 2 |
Median: 15954.1 Range: 14125.4 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | CA3 | 2 |
Median: 13000 Range: 13000 to 13000 |
Ki |
PMID: 18579385 PMID: 20185318 |
| NPC204932 | SMN1;SMN2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | LMNA | 2 |
Median: 23350.75 Range: 11220.2 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | HPGD | 2 |
Median: 14501.5 Range: 11220.2 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | GMNN | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC204932 | CA4 | 3 |
Median: 10900 Range: 10900 to 10900 |
Ki |
PMID: 18579385 PMID: 20185318 PMID: 22245047 |
| NPC219876 | KDM4E | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | POLB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC48342 | SLC6A4 | 1 | 10755 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC61477 | MAPT | 2 |
Median: 14125.4 Range: 14125.4 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | CA14 | 1 | 11550 | Ki |
PMID: 20674354 |
| NPC61477 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61477 | CA13 | 1 | 10510 | Ki |
PMID: 20674354 |