Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC137949 GAA 2 Median: 35481.3
Range: 35481.3 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 ALDH1A1 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 MAPT 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC137949 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC137949 GLA 2 Median: 15954.1
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC206264 KDM4E 1 43351.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219913 ALDH5A1 1 24700 IC50 PMID: 16290145
NPC219913 ABAT 1 16500 IC50 PMID: 16290145
NPC70744 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC81010 ESR1 1 16120 EC50 PMID: 23608764
NPC95162 CYP2C19 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC95162 ALDH1A1 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC95162 CYP2C9 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC95162 CASP1 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC95162 HPGD 2 Median: 20483.9
Range: 15848.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC95162 CASP7 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC95162 MAPK1 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC95162 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC137949 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC137949 SMN1;SMN2 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC29883 CA2 2 Median: 10600
Range: 10600 to 10600
Ki PMID: 18501600
PMID: 18579385
NPC70744 CA3 1 11100 Ki PMID: 20185318
NPC70744 CA4 1 10800 Ki PMID: 20185318
NPC70744 CA5B 1 10500 Ki PMID: 20185318
NPC81010 HCAR2 1 14000 Ki PMID: 21167710
NPC95162 TDP1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC95162 MAPT 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC95162 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862