Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC14030 TOP1 1 40000 IC50 PMID: 1324981
NPC178134 CYP2C9 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 CYP2C19 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 THRB 2 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 CARM1 1 25000 IC50 DOI: 10.1039/C1MD00199J
NPC178134 GSR 1 22800 IC50 PMID: 19015351
NPC178134 EPHX2 1 20700 IC50 PMID: 24679441
NPC178134 ATM 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 MAPK1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC187770 TYR 1 32500 IC50 PMID: 25726329
NPC225710 SELL 1 27600 IC50 PMID: 17302397
NPC225710 GAPDH 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 MAPK1 2 Median: 23753.05
Range: 22387.2 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELP 1 19100 IC50 PMID: 17302397
NPC225710 SMN1;SMN2 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264145 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264145 POLB 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264145 LMNA 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264145 KDM4E 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264145 XDH 1 15520 IC50 PMID: 12444671
NPC7839 THRB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC7839 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC7839 KMT2A 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC7839 MAPT 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 CA5B 1 12700 Ki PMID: 20185318
NPC178134 MAPT 8 Median: 21169.9
Range: 12589.3 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 TP53 2 Median: 22106.05
Range: 12589.3 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC178134 KMT2A 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178134 CA3 1 10500 Ki PMID: 20185318
NPC225710 FUT4 1 14000 IC50 DOI: 10.1039/C4MD00086B
NPC264145 GAA 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862