Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC180508 ABCB1 1 42000 IC50 PMID: 16686543
NPC180508 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC180508 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 TDP1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 THRB 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 SMN1;SMN2 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 HPGD 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC8283 ESR1 1 26200 IC50 PMID: 20493686
NPC8283 ESR2 1 14700 IC50 PMID: 20493686
NPC180508 MAPT 2 Median: 13534.55
Range: 11220.2 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC180508 GAA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC297186 MAPT 2 Median: 28628.85
Range: 12589.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC29883 CA2 2 Median: 10600
Range: 10600 to 10600
Ki PMID: 18501600
PMID: 18579385