Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC137949 GAA 2 Median: 35481.3
Range: 35481.3 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 ALDH1A1 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 MAPT 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC137949 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC137949 GLA 2 Median: 15954.1
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC157340 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC163984 ALDH1A1 2 Median: 25285.5
Range: 22387.2 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC235190 TDP1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC235190 ALOX15 1 16700 IC50 PMID: 23047230
NPC247553 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 AKR1B1 1 22900 IC50 PMID: 20805028
NPC247553 CASP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 CASP7 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 AR 2 Median: 19027.305
Range: 19000 to 19054.61
IC50 PMID: 20226658
PMID: 20226658
NPC43246 SLC28A2 1 32000 IC50 PMID: 23388705
NPC49074 PTGS1 1 36000 IC50 PMID: 16038536
NPC74539 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC74539 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC74539 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC137949 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC137949 SMN1;SMN2 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 PTGS1 1 11000 IC50 PMID: 16038536
NPC74539 MAOA 1 13800 IC50 PMID: 23517722
NPC74539 CYP2A6 1 12000 Ki PMID: 16248836