Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC120163 MAPT 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC120163 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC241498 ATM 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC241498 TDP1 2 Median: 46590.9
Range: 22387.2 to 70794.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC241498 MAPT 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC50898 APEX1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC50898 THRB 2 Median: 44964.7
Range: 39810.7 to 50118.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC50898 BACE1 2 Median: 38500
Range: 38500 to 38500
IC50 PMID: 22243648
DOI: 10.1007/s00044-012-0353-y
NPC50898 BCHE 1 37400 Ki PMID: 19879672
NPC50898 HBB 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC50898 HSD17B10 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC50898 DAPK1 1 31000 IC50 PMID: 26322379
NPC50898 NPSR1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC50898 HPGD 3 Median: 28183.8
Range: 22387.2 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC50898 NFKB1 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC50898 MAPK1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC50898 SMN1;SMN2 5 Median: 22387.2
Range: 14125.4 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC50898 MAOB 1 12800 IC50 PMID: 20045650
NPC50898 CYP2D6 2 Median: 26200
Range: 12589.3 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC50898 GMNN 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC50898 LMNA 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC50898 AKR1B1 1 11900 IC50 PMID: 26529431
NPC50898 KDM4E 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862