Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC127624 CD38 1 17000 IC50 PMID: 21641214
NPC138113 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC17810 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC17810 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC183845 GRM2 1 35000 Ki PMID: 10893301
NPC209560 HSD17B10 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC209560 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209560 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC209560 HPGD 2 Median: 30300.1
Range: 25118.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC209560 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC229113 TSHR 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234560 PMP22 1 47754.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234560 AKR1B10 1 32200 IC50 PMID: 26529431
NPC234560 HSD17B10 3 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 ALDH1A1 7 Median: 35481.3
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 PKM 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 KDM4E 4 Median: 29903.3
Range: 19952.6 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC234560 CYP3A4 4 Median: 20483.9
Range: 15848.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 CYP2D6 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234560 HPGD 4 Median: 28370.85
Range: 14125.4 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC41326 POLB 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC41326 GLA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC41326 GAA 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC41326 BLM 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC41326 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC41326 ALDH1A1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC41326 RECQL 2 Median: 27005
Range: 22387.2 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC41326 MAPT 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC68889 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209560 SMN1;SMN2 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC229113 CYP1A2 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC230085 USP2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234560 SMN1;SMN2 4 Median: 22016.35
Range: 12589.3 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC41326 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC41326 NR1I2 1 12000 IC50 PMID: 24828006