Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC156222 POLB 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 EPHX2 1 24300 IC50 PMID: 24679441
NPC176740 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC181465 XDH 1 14800 IC50 PMID: 9461655
NPC203891 XDH 1 36500 IC50 PMID: 10425142
NPC203891 PKM 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC203891 MAPT 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC248573 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC248573 HPGD 2 Median: 25665.1
Range: 15848.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC248573 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34864 L3MBTL1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34864 PMP22 1 30131.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34864 ALDH1A1 3 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34864 BLM 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34864 MTOR 2 Median: 23280.9
Range: 23280.9 to 23280.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34864 KDM4E 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34864 SMN1;SMN2 3 Median: 25118.9
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC9609 NR0B1 1 34985 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC156222 MAPT 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC248573 MAPT 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC248573 THPO 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC248573 KDM4E 2 Median: 20386.55
Range: 12589.3 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC248573 HSD17B10 4 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34864 MYLK 2 Median: 12000
Range: 12000 to 12000
IC50 PMID: 16441060
PMID: 18077363