Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC10286 | CYP2C9 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | CYP3A4 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | L3MBTL1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | HPGD | 2 |
Median: 33552.05 Range: 31622.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | HSD17B10 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | ALDH1A1 | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | KDM4E | 2 |
Median: 31832.55 Range: 28183.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | ALOX15 | 1 | 23900 | IC50 |
PMID: 23047230 |
| NPC180006 | ATM | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | GLA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC189470 | PTPRCAP | 1 | 17000 | IC50 |
DOI: 10.1016/0960-894X(95)00250-W |
| NPC209296 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209296 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC213 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC243509 | BACE1 | 2 |
Median: 61150 Range: 30500 to 91800 |
IC50 |
PMID: 19939683 PMID: 22222157 |
| NPC243509 | GAA | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC243509 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC243509 | ABCB1 | 1 | 28000 | IC50 |
DOI: 10.1039/C4MD00196F |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC247553 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | GAA | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | AKR1B1 | 1 | 22900 | IC50 |
PMID: 20805028 |
| NPC247553 | CASP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | CASP7 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC28169 | ERN1 | 1 | 20250 | IC50 |
Patent: Patent: US8614253 B2 |
| NPC294409 | AKR1B10 | 1 | 36100 | IC50 |
PMID: 26529431 |
| NPC294409 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | KDM4E | 2 |
Median: 33552.05 Range: 31622.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | HSD17B10 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CYP3A4 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | SMN1;SMN2 | 2 |
Median: 18867.7 Range: 17782.8 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | MAPK1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | ALOX12 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC298796 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC298796 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC298796 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC298796 | HPGD | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | ATM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | CYP1A2 | 1 | 34647 | IC50 |
PMID: 20696580 |
| NPC302950 | GSK3B | 1 | 26900 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC302950 | TP53 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC305016 | CYP3A4 | 1 | 23200 | Ki |
PMID: 16248836 |
| NPC306397 | SIRT5 | 1 | 46600 | IC50 |
PMID: 24900427 |
| NPC306397 | SIRT1 | 7 |
Median: 73000 Range: 25000 to 149000 |
IC50 |
PMID: 19700324 PMID: 23318905 PMID: 24900427 PMID: 25275824 PMID: 25549554 PMID: 26696402 DOI: 10.1039/C1MD00199J |
| NPC40818 | ABCB1 | 1 | 39000 | IC50 |
PMID: 21354800 |
| NPC40818 | ABCG2 | 2 |
Median: 18000 Range: 17000 to 19000 |
IC50 |
PMID: 21354800 PMID: 21354800 |
| NPC44328 | TDP1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC74539 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC74539 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC74539 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC79056 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC79056 | CTDSP1 | 1 | 20733 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | ALDH1A1 | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | MAPT | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | KDM4E | 3 |
Median: 25118.9 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85233 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC88445 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC88445 | LMNA | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC96286 | ALOX5 | 1 | 36200 | IC50 |
PMID: 9544564 |
| NPC96286 | ABCB1 | 1 | 34000 | IC50 |
DOI: 10.1039/C4MD00196F |
| NPC96286 | ALDH1A1 | 2 |
Median: 36426.1 Range: 28183.8 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC96286 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC10286 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC180006 | MAPT | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CBR1 | 1 | 12710 | IC50 |
PMID: 19097799 |
| NPC298796 | GLA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC302950 | HSD17B10 | 2 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC40818 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC74539 | MAOA | 1 | 13800 | IC50 |
PMID: 23517722 |
| NPC74539 | CYP2A6 | 1 | 12000 | Ki |
PMID: 16248836 |
| NPC85233 | ABCB1 | 1 | 11500 | IC50 |
PMID: 11743742 |
| NPC85233 | MAPK1 | 2 |
Median: 21421.5 Range: 11220.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |