Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC100998 | PRKCA | 1 | 19000 | IC50 |
PMID: 9834166 |
| NPC113733 | POLB | 2 |
Median: 51840 Range: 43400 to 60280 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC197316 | L3MBTL1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC287597 | CYP19A1 | 1 | 35300 | IC50 |
PMID: 21261296 |
| NPC314940 | METAP1 | 1 | 21500 | IC50 |
PMID: 20621724 |
| NPC314940 | TSHR | 4 |
Median: 29881.65 Range: 19952.6 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | CYP3A4 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | ATM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | HPGD | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | LMNA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | MAOA | 1 | 26000 | Ki |
PMID: 22071524 |
| NPC43945 | CDC25C | 2 |
Median: 18900 Range: 18800 to 19000 |
IC50 |
PMID: 15501045 PMID: 16216500 |
| NPC43945 | BLM | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | PKM | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC64141 | MMP9 | 1 | 14280 | IC50 |
PMID: 22658537 |
| NPC18335 | XDH | 1 | 10890 | IC50 |
PMID: 17379526 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC43945 | HBB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC43945 | GSR | 2 |
Median: 14100 Range: 12100 to 16100 |
Ki |
PMID: 15537352 PMID: 15537352 |
| NPC43945 | ALDH1A1 | 2 |
Median: 12672.8 Range: 11220.2 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
| NPC64141 | MMP13 | 1 | 11090 | IC50 |
PMID: 22658537 |