Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC115284 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115284 | SMN1;SMN2 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | RAD52 | 1 | 15210 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC141765 | PPARD | 1 | 18110 | EC50 |
PMID: 27450788 |
| NPC141765 | PTPN1 | 1 | 15010 | IC50 |
PMID: 24224843 |
| NPC145304 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC145304 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC167546 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC167546 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC167546 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC256849 | ADORA1 | 5 |
Median: 44900 Range: 44000 to 44900 |
Ki |
PMID: 21664729 PMID: 23602401 PMID: 24139167 PMID: 24139167 PMID: 24164628 |
| NPC256849 | ADORA2A | 1 | 20472 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC290005 | OPRD1 | 1 | 44174 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC290005 | RAD52 | 1 | 35210 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC290005 | MAPT | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC317145 | TDP1 | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC47936 | CYP3A4 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC47936 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC47936 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85661 | ALDH1A1 | 2 |
Median: 42239.55 Range: 39810.7 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13826 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC145304 | MAPT | 2 |
Median: 15186.05 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC16452 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC16452 | CYP2D6 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC167546 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18335 | XDH | 1 | 10890 | IC50 |
PMID: 17379526 |
| NPC217748 | GAA | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC256849 | ADORA3 | 3 |
Median: 13300 Range: 13300 to 13300 |
Ki |
PMID: 12139454 PMID: 24139167 PMID: 24139167 |
| NPC256849 | ADORA2B | 10 |
Median: 27150 Range: 10400 to 33800 |
Ki |
PMID: 12014951 PMID: 19569717 PMID: 19569717 PMID: 20188574 PMID: 20537438 PMID: 21664729 PMID: 24139167 PMID: 24139167 PMID: 24164628 PMID: 26824742 |
| NPC256849 | GDA | 1 | 10200 | Ki |
PMID: 20716488 |
| NPC85661 | MAPT | 3 |
Median: 14125.4 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |