Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC10251 L3MBTL1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103213 UGT1A1 2 Median: 43500
Range: 40000 to 47000
IC50 PMID: 21030469
PMID: 21030469
NPC103213 ALOX15 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103213 MAPT 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC171736 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC171736 PPARA 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC171736 PPARD 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC214067 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214067 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC261831 BLM 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 CYP19A1 1 32700 IC50 PMID: 16643058
NPC261831 TOP1 1 31000 IC50 PMID: 12444712
NPC261831 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 FABP4 1 26100 IC50 PMID: 20471252
NPC261831 KMT2A 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 ATM 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 HSD17B10 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC99886 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99886 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC10251 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC103213 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC192638 TOP2A 1 10400 IC50 PMID: 11754608
NPC261831 KCNH2 1 10410 EC50 PubChem BioAssay data set
CHEMBL1201862