Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC18188 SLC6A12 1 36000 IC50 PMID: 8057281
NPC18188 NPSR1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC18188 TSHR 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC18188 CYP1A2 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC18188 THRB 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204717 CYP2D6 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204717 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC220765 RECQL 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC220765 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC220765 CYP3A4 4 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC220765 CYP2C9 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC232533 SLC22A1 1 28000 IC50 PMID: 18788725
NPC236347 CYP2D6 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC236347 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC236347 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC236347 ALOX12 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC236347 MTOR 2 Median: 24701.25
Range: 23280.9 to 26121.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC236347 RECQL 2 Median: 64992.3
Range: 17782.8 to 112201.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC236347 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC242885 NR3C1 1 35000 IC50 PMID: 17583952
NPC96102 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC96102 CYP2D6 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC96102 CYP2A13 1 16000 Ki PMID: 22696418
NPC96102 CTSK 1 15000 IC50 PMID: 11975521
NPC236347 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC96102 NFKB1 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862