Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC169749 | DPP4 | 1 | 37150 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC169749 | ALPL | 1 | 33200 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC169749 | ALPPL2 | 1 | 32300 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC169749 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC169749 | AMY1A;AMY1B;AMY1C | 1 | 30200 | IC50 |
PMID: 18507367 |
| NPC169749 | AKR1B1 | 1 | 29000 | IC50 |
PMID: 18165015 |
| NPC169749 | CD38 | 1 | 24800 | IC50 |
PMID: 21641214 |
| NPC169749 | DAPK1 | 1 | 23000 | IC50 |
PMID: 26322379 |
| NPC169749 | ABCC2 | 1 | 22000 | IC50 |
PMID: 19725578 |
| NPC169749 | ABCC1 | 1 | 20000 | IC50 |
PMID: 19725578 |
| NPC169749 | CYP2D6 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC169749 | APOBEC3A | 1 | 17500 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC169749 | MTOR | 2 |
Median: 19881.25 Range: 16481.6 to 23280.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC169749 | BLM | 3 |
Median: 14125.4 Range: 14125.4 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC169749 | ALOX12 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC173637 | PIM2 | 1 | 25000 | IC50 |
PMID: 18163587 |
| NPC173637 | L3MBTL1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC173637 | XDH | 1 | 14740 | IC50 |
PMID: 12444671 |
| NPC20791 | PMP22 | 1 | 47754.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GALK1 | 1 | 42128.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK2 | 1 | 40000 | IC50 |
PMID: 17178224 |
| NPC20791 | CD38 | 1 | 37900 | IC50 |
PMID: 21641214 |
| NPC20791 | SORD | 2 |
Median: 106300 Range: 35600 to 177000 |
IC50 |
PMID: 8893834 PMID: 12672241 |
| NPC20791 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | EPHX2 | 1 | 33540 | IC50 |
PMID: 24679441 |
| NPC20791 | DPP4 | 2 |
Median: 81365 Range: 32730 to 130000 |
IC50 |
PMID: 18650094 DOI: 10.1039/C0MD00245C |
| NPC20791 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ADORA3 | 1 | 30000 | Ki |
PMID: 8576921 |
| NPC20791 | PTGS2 | 1 | 28600 | IC50 |
PMID: 17378609 |
| NPC20791 | BLM | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | TDP1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ALDH1A1 | 6 |
Median: 37646 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK6 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
| NPC20791 | PTPN1 | 2 |
Median: 23300 Range: 23300 to 23300 |
IC50 |
PMID: 12419367 PMID: 19297174 |
| NPC20791 | KMT2A | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | AMY1A;AMY1B;AMY1C | 1 | 21400 | IC50 |
PMID: 18507367 |
| NPC20791 | SYK | 1 | 20000 | IC50 |
PMID: 22257213 |
| NPC20791 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | APEX1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CYP2D6 | 1 | 18800 | IC50 |
PMID: 22328583 |
| NPC20791 | USP2 | 2 |
Median: 25057.75 Range: 18492.7 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GPR35 | 1 | 15400 | IC50 |
PMID: 24900447 |
| NPC20791 | APP | 1 | 15300 | IC50 |
PMID: 26719209 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC250436 | CREBBP | 1 | 50000 | IC50 |
PMID: 26701186 |
| NPC250436 | EP300 | 1 | 30000 | IC50 |
PMID: 26701186 |
| NPC250436 | MMP7 | 1 | 21500 | IC50 |
PMID: 19524436 |
| NPC250436 | PIN1 | 1 | 20000 | IC50 |
PMID: 23796453 |
| NPC279121 | GALK1 | 1 | 47269 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | TSHR | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2C9 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | GAA | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | DAPK1 | 1 | 21000 | IC50 |
PMID: 26322379 |
| NPC279121 | CDK2 | 1 | 20000 | IC50 |
PMID: 17178224 |
| NPC279121 | TDP1 | 2 |
Median: 29881.65 Range: 19952.6 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | ABCB1 | 1 | 19600 | IC50 |
PMID: 15240100 |
| NPC279121 | GPR35 | 1 | 18600 | IC50 |
PMID: 24900447 |
| NPC279121 | AMY1A;AMY1B;AMY1C | 1 | 18400 | IC50 |
PMID: 18507367 |
| NPC279121 | MMP3 | 1 | 16200 | IC50 |
PMID: 22658537 |
| NPC279121 | CYP2C19 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | BLM | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC35167 | EPHX2 | 1 | 18640 | IC50 |
PMID: 24679441 |
| NPC50898 | APEX1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | THRB | 2 |
Median: 44964.7 Range: 39810.7 to 50118.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | BACE1 | 2 |
Median: 38500 Range: 38500 to 38500 |
IC50 |
PMID: 22243648 DOI: 10.1007/s00044-012-0353-y |
| NPC50898 | BCHE | 1 | 37400 | Ki |
PMID: 19879672 |
| NPC50898 | HBB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | DAPK1 | 1 | 31000 | IC50 |
PMID: 26322379 |
| NPC50898 | NPSR1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HPGD | 3 |
Median: 28183.8 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | NFKB1 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | MPI | 1 | 30965 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | RECQL | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | MAPT | 2 |
Median: 16815.85 Range: 15848.9 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC87317 | MMP7 | 1 | 20000 | IC50 |
PMID: 19524436 |
| NPC169749 | HSP90AB1 | 1 | 13500 | IC50 |
PMID: 24548207 |
| NPC20791 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | PIK3CG | 1 | 13790 | IC50 |
PMID: 25050878 |
| NPC20791 | PREP | 1 | 13000 | IC50 |
PMID: 18650094 |
| NPC20791 | LCK | 2 |
Median: 13000 Range: 13000 to 13000 |
IC50 |
PMID: 1995903 PMID: 16441060 |
| NPC20791 | CALM1;CALM2;CALM3 | 1 | 12970 | IC50 |
PMID: 21129983 |
| NPC20791 | PLAU | 1 | 12100 | IC50 |
PMID: 24610996 |
| NPC20791 | CA5B | 1 | 11900 | Ki |
PMID: 20185318 |
| NPC20791 | CYP2C19 | 1 | 10500 | IC50 |
PMID: 22328583 |
| NPC20791 | MMP12 | 1 | 10230 | IC50 |
PMID: 22658537 |
| NPC20791 | HIF1AN | 1 | 10200 | IC50 |
PMID: 19822432 |
| NPC20791 | CYP2C9 | 1 | 10200 | IC50 |
PMID: 22328583 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC250436 | ELANE | 1 | 12800 | IC50 |
PMID: 20004577 |
| NPC279121 | MAPT | 3 |
Median: 12589.3 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | SYK | 1 | 12000 | IC50 |
PMID: 22257213 |
| NPC279121 | HPGD | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | MMP13 | 1 | 10050 | IC50 |
PMID: 22658537 |
| NPC294852 | CYP1A1 | 1 | 10973 | IC50 |
PMID: 20696580 |
| NPC50898 | SMN1;SMN2 | 5 |
Median: 22387.2 Range: 14125.4 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAOB | 1 | 12800 | IC50 |
PMID: 20045650 |
| NPC50898 | CYP2D6 | 2 |
Median: 26200 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | LMNA | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | AKR1B1 | 1 | 11900 | IC50 |
PMID: 26529431 |
| NPC50898 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |