Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC111132 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC15566 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC15566 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC15566 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC15566 GABRR1 1 16000 EC50 PMID: 10780899
NPC163076 CA2 7 Median: 20000
Range: 20000 to 20000
Ki PMID: 15357993
PMID: 15454240
PMID: 15501038
PMID: 21208801
PMID: 26525863
PMID: 26853167
PMID: 27283786
NPC163099 CYP1A2 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC176740 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 EPHX2 1 24300 IC50 PMID: 24679441
NPC176740 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC226453 APEX1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC226453 CYP1A2 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC260491 MAPT 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC260491 RECQL 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC309330 NFKB1 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC163099 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC260491 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862