CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Hydrangea Macrophylla

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TTGTAACCTGCAACAGCAGAACGACCAGCGAACTTGTGAAAATATATTGAGGTGCCCAGTGTGCCTCAATGCCCGGACGTGCTCGTAATGGGTGAGATCTAGGCACAATAATGAACCCCGGCACGAGCTGTGCCAAGGAAAATTGATGAAGACAGAGTCCCTTGCTGCCTCGCTCTGCGGGTGTGTGCTCGGGGCAAAGCTTCTTTCACGAAACACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCTTGAAGCCATTAGGCCGAAGGCACGTCTGCCTGGGCGTCTCGCAACGCGTCGCCCCCAACCCTTCGTCTCTCTTCGAGCGTTGGACATTGGGGGCAGATGATGGCCTCCTGTGTGCGCATTTGCATGCAGTTGGCCTAAAAGAAAAGTTCCTGACAATGGATCGTCACGGCACGTGGTGGTTGAAGAACCTAGTCGCGTTCTGTTGTTGGCGCCCCCATTGTCGGGCGAAGCTATGACCCTCGTGCGTCGTCACGAACGGCGCATCGA

Click for details-----ITS1

Click for details-----ITS2

AACGCGTCGCCCCCAACCCTTCGTCTCTCTTTGAGCGTTGGACACTGGGGGCAGATGATGGCCTCCTGTGCGCATTTGCATGCAGTTGGCCTAAAAGAAAAGTTCCTGACAATGGATCGTCACGGCACGTGGTGGTTGGAAAACCTAGTCGCGTTCTGCTGTTGGCGCCCCCATTGTCGGGAGAAGCTATGACCCTCATGCGTCGTCACGAACGGCGCATCGACAGCGACCCCAGGTCA

Taxonomic Information

Plant ID: NPO9360
Plant Latin Name: Hydrangea Macrophylla
Taxonomy Genus: Hydrangea
Taxonomy Family: Hydrangeaceae

Plant External Links:

NCBI TaxonomyDB: 23110
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:

China; Indonesia; India

Traditional Medicine System:

Indian Folk; TCM

Medicinal Functions:

Antiperiodic; Antitussive; Diuretic

Geographical Distribution

India; Indonesia; China

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

22 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

16 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)