Antiecchymotic; Antiinflammatory; Antirheumatic; Antispasmodic; Aperient; Bitter; Carminative; Emmenagogue; Sedative; Stimulant; Stings; Stomachic; Vasodilator; Vermifuge
Brazil; Afghanistan; Italy; Peru; Canada; France; Ireland; Argentina; Bolivia; Norway; Ecuador; Australia; Iran; Algeria; Turkey; Germany; Chile; Belgium; China; Iraq; Poland; Spain; Ukraine; Netherlands; Denmark; Philippines; Indonesia; United States; Morocco; Sweden; Belarus; Switzerland; New Zealand; Russia; Bulgaria; Romania; Albania; Portugal; Mexico; Tajikistan; Uruguay; United Kingdom; Austria; Greece; Paraguay; Hungary; Cyprus
Ingredient ID: NPC98320
Ingredient ID: NPC96010
Ingredient ID: NPC9218
Ingredient ID: NPC91604
Ingredient ID: NPC91546
Ingredient ID: NPC8605
Ingredient ID: NPC60660
Ingredient ID: NPC55187
Ingredient ID: NPC4785
Ingredient ID: NPC46981
Ingredient ID: NPC4574
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Ingredient ID: NPC40488
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Ingredient ID: NPC306100
Ingredient ID: NPC300682
Ingredient ID: NPC297712
Ingredient ID: NPC29674
Ingredient ID: NPC294902
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Ingredient ID: NPC286405
Ingredient ID: NPC278102
Ingredient ID: NPC272282
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Ingredient ID: NPC266187
Ingredient ID: NPC265392
Ingredient ID: NPC264179
Ingredient ID: NPC26027
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Ingredient ID: NPC248043
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Ingredient ID: NPC242709
Ingredient ID: NPC226941
Ingredient ID: NPC222480
Ingredient ID: NPC218753
Ingredient ID: NPC217910
Ingredient ID: NPC203891
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Ingredient ID: NPC192690
Ingredient ID: NPC178134
Ingredient ID: NPC172115
Ingredient ID: NPC171929
Ingredient ID: NPC166552
Ingredient ID: NPC165384
Ingredient ID: NPC161571
Ingredient ID: NPC15898
Ingredient ID: NPC1580
Ingredient ID: NPC156654
Ingredient ID: NPC156461
Ingredient ID: NPC152172
Ingredient ID: NPC138751
Ingredient ID: NPC136073
Ingredient ID: NPC135382
Ingredient ID: NPC131530
Ingredient ID: NPC120022
Ingredient ID: NPC119803
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 2 | CYP2D6 | Cytochrome P450 2D6 | P10635 | CHEMBL289 |
Cytochrome P450 | Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
Therapeutic Target | Enzyme | RECQL | ATP-dependent DNA helicase Q1 | P46063 | CHEMBL1293236 |
Therapeutic Target | Enzyme | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | P27695 | CHEMBL5619 |
Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
Therapeutic Target | Enzyme | HPGD | 15-hydroxyprostaglandin dehydrogenase [NAD+] | P15428 | CHEMBL1293255 |
Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
Therapeutic Target | Lyase | CA14 | Carbonic anhydrase XIV | Q9ULX7 | CHEMBL3510 |
Therapeutic Target | Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
Therapeutic Target | Metallo protease | MMP9 | Matrix metalloproteinase 9 | P14780 | CHEMBL321 |
Therapeutic Target | Metallo protease | MMP2 | Matrix metalloproteinase-2 | P08253 | CHEMBL333 |
Therapeutic Target | Metallo protease | MMP1 | Matrix metalloproteinase-1 | P03956 | CHEMBL332 |
Therapeutic Target | Methyl-lysine/arginine binding protein | SMN1 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
Therapeutic Target | Other cytosolic protein | HSPA1A | Heat shock 70 kDa protein 1 | P0DMV8 | CHEMBL5460 |
Therapeutic Target | Oxidoreductase | PTGS2 | Cyclooxygenase-2 | P35354 | CHEMBL230 |
Therapeutic Target | Oxidoreductase | AKR1B1 | Aldose reductase | P15121 | CHEMBL1900 |
Therapeutic Target | Oxidoreductase | NQO2 | Quinone reductase 2 | P16083 | CHEMBL3959 |
Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Therapeutic Target | Protein Kinase | CSNK2A1 | Casein kinase II alpha | P68400 | CHEMBL3629 |
Therapeutic Target | Protein Kinase | MET | Hepatocyte growth factor receptor | P08581 | CHEMBL3717 |
Therapeutic Target | Protein Kinase | NUAK1 | NUAK family SNF1-like kinase 1 | O60285 | CHEMBL5784 |
Therapeutic Target | Protein Kinase | EGFR | Epidermal growth factor receptor erbB1 | P00533 | CHEMBL203 |
Therapeutic Target | Protein Kinase | SRC | Tyrosine-protein kinase SRC | P12931 | CHEMBL267 |
Therapeutic Target | Protein Kinase | TEK | Tyrosine-protein kinase TIE-2 | Q02763 | CHEMBL4128 |
Therapeutic Target | Protein Kinase | KDR | Vascular endothelial growth factor receptor 2 | P35968 | CHEMBL279 |
Therapeutic Target | Protein Kinase | INSR | Insulin receptor | P06213 | CHEMBL1981 |
Therapeutic Target | Protein Kinase | IGF1R | Insulin-like growth factor I receptor | P08069 | CHEMBL1957 |
Therapeutic Target | Secreted protein | THPO | Thrombopoietin | P40225 | CHEMBL1293256 |
Therapeutic Target | Serine protease | DPP4 | Dipeptidyl peptidase IV | P27487 | CHEMBL284 |
Drug Transporter | SLC superfamily of solute carriers | SLC22A6 | Solute carrier family 22 member 6 | Q4U2R8 | CHEMBL1641347 |
Drug Transporter | SLC superfamily of solute carriers | SLC22A3 | Solute carrier family 22 member 3 | O75751 | CHEMBL2073673 |
Therapeutic Target | Small molecule receptor (family A GPCR) | CNR2 | Cannabinoid CB2 receptor | P34972 | CHEMBL253 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADORA2A | Adenosine A2a receptor | P29274 | CHEMBL251 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADORA3 | Adenosine A3 receptor | P0DMS8 | CHEMBL256 |
Therapeutic Target | Small molecule receptor (family A GPCR) | CNR1 | Cannabinoid CB1 receptor | P21554 | CHEMBL218 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADORA1 | Adenosine A1 receptor | P30542 | CHEMBL226 |
Therapeutic Target | Small molecule receptor (family A GPCR) | GPR35 | G-protein coupled receptor 35 | Q9HC97 | CHEMBL1293267 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Transcription factor | SMAD3 | Mothers against decapentaplegic homolog 3 | P84022 | CHEMBL1293258 |
Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
Therapeutic Target | Transcription factor | PAX8 | Paired box protein Pax-8 | Q06710 | CHEMBL2362980 |
Therapeutic Target | Transferase | POLH | DNA polymerase eta | Q9Y253 | CHEMBL5542 |
Therapeutic Target | Transferase | PIK3CA | PI3-kinase p110-alpha subunit | P42336 | CHEMBL4005 |
Therapeutic Target | Transferase | POLI | DNA polymerase iota | Q9UNA4 | CHEMBL5391 |
Therapeutic Target | Transferase | PIK3CB | PI3-kinase p110-beta subunit | P42338 | CHEMBL3145 |
Therapeutic Target | Transient receptor potential channel | TRPA1 | Transient receptor potential cation channel subfamily A member 1 | O75762 | CHEMBL6007 |
Therapeutic Target | Unclassified protein | GMNN | Geminin | O75496 | CHEMBL1293278 |
Therapeutic Target | Unclassified protein | SHH | Sonic hedgehog protein | Q15465 | CHEMBL5602 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 157 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT04867252 | Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome | polycystic ovary syndrome | Resveratrol (NPC161571) | NP level |
NCT01123525 | Adenosine Cardioplegia | angina pectoris | Adenosine (NPC156461) | NP level |
NCT04416334 | PREEMPTIVE THERAPY WITH COLCHICINE IN PATIENTS OLDER THAN 60 YEARS WITH HIGH RISK OF SEVERE PNEUMONIAE DUE TO CORONAVIRUS | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04870424 | Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT05118737 | Adding Colchicine to Tocilizumab in Patients With Severe COVID-19 Pneumonia. | COVID-19 | Colchicine (NPC226941) | NP level |
NCT02602028 | The Comparison of the Efficacy of Once and Twice Daily Colchicine Dosage in Pediatric Patients With FMF | familial Mediterranean fever | Colchicine (NPC226941) | NP level |
NCT00714103 | 8-Chloro-Adenosine in Chronic Lymphocytic Leukemia | chronic lymphocytic leukemia | Adenosine (NPC156461) | NP level |
NCT04392362 | A Trial to Compare American Heart Association (AHA) and Simple (SIM)Method to Give Adenosine to Treat Supra-ventricular Tachycardia (SVT) | ventricular tachycardia | Adenosine (NPC156461) | NP level |
NCT01593644 | Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler | coronary artery disease | Adenosine (NPC156461) | NP level |
NCT02366091 | Inflammation and Coronary Endothelial Function | coronary artery disease | Colchicine (NPC226941) | NP level |
NCT02245932 | Resveratrol In Chronic Obstructive Pulmonary Disease (COPD) Patients (CARMENS-trial) | chronic obstructive pulmonary disease | Resveratrol (NPC161571) | NP level |
NCT01321151 | Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers | concussion | Resveratrol (NPC161571) | NP level |
NCT00751491 | Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI) | angina pectoris | Adenosine (NPC156461) | NP level |
NCT01564381 | Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women | cardiovascular disease | Resveratrol (NPC161571) | NP level |
NCT02139046 | Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout | gout | Colchicine (NPC226941) | NP level |
NCT00370760 | Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR) | proliferative vitreoretinopathy | Colchicine (NPC226941) | NP level |
NCT04355143 | Colchicine to Reduce Cardiac Injury in COVID-19 (COLHEART-19) | COVID-19 | Colchicine (NPC226941) | NP level |
NCT02330796 | Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout | gout | Colchicine (NPC226941) | NP level |
NCT00580905 | Role of Adenosine in the Release of VEGF and Cytokines | inflammation | Adenosine (NPC156461) | NP level |
NCT01994226 | Colchicine Or Naproxen Treatment for ACute gouT | gout | Colchicine (NPC226941) | NP level |
NCT04472611 | Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial | COVID-19 | Colchicine (NPC226941) | NP level |
NCT02062190 | Resveratrol, Cardiovascular Risk Markers And Cognitive Performance In Patients With Schizophrenia | schizophrenia | Resveratrol (NPC161571) | NP level |
NCT03097211 | Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT03743636 | Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease | peripheral arterial disease | Resveratrol (NPC161571) | NP level |
NCT04756128 | Impact of Colchicine and Low-dose Naltrexone on COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04705987 | Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure | heart failure | Colchicine (NPC226941) | NP level |
NCT04648917 | GASC1 Inhibitor Caffeic Acid for Squamous Esophageal Cell Cancer (ESCC) | esophageal cancer | Caffeic Acid (NPC294902) | NP level |
NCT04160117 | Impact of Short-course Colchicine Versus Placebo After Pulmonary Vein Isolation (IMPROVE-PVI Pilot) | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT03095105 | Pharmacokinetic Profile of BIA 6-512 in Healthy Elderly Subjects Versus Healthy Young Subjects | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT00284323 | Salvage: Postconditioning With Adenosine for STEMI | ST Elevation Myocardial Infarction | Adenosine (NPC156461) | NP level |
NCT01481233 | Oral Colchicine in Men With Castrate Resistant Prostate Cancer | prostate cancer | Colchicine (NPC226941) | NP level |
NCT01339884 | A Study of Resveratrol as Treatment for Friedreich Ataxia | Friedreich ataxia | Resveratrol (NPC161571) | NP level |
NCT05459974 | Use of Colchicine to Decrease Atrial Fibrillation Recurrence After Ablation | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT03446625 | Resveratrol as a Preventive Treatment of OHSS | infertility | Resveratrol (NPC161571) | NP level |
NCT05279690 | Pilot Trial of Colchicine in Urothelial Cancer and Other Solid Tumors | neoplasm;urogenital neoplasm | Colchicine (NPC226941) | NP level |
NCT00565188 | Application of ATP Infusions in Palliative Home Care | cancer | Adenosine (NPC156461) | NP level |
NCT03905759 | Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABG | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT03156816 | COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction | myocardial infarction | Colchicine (NPC226941) | NP level |
NCT05159219 | Colchicine for the Prevention of Vascular Events After an Acute Intracerebral Hemorrhage | intracranial hemorrhage | Colchicine (NPC226941) | NP level |
NCT00590070 | THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myocardial Infarction | myocardial infarction | Adenosine (NPC156461) | NP level |
NCT00000577 | Asthma Clinical Research Network (ACRN) | asthma;lung disease | Colchicine (NPC226941) | NP level |
NCT04359095 | Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in Colombia | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04322682 | Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04381936 | Randomised Evaluation of COVID-19 Therapy | severe acute respiratory syndrome | Colchicine (NPC226941) | NP level |
NCT01126229 | Resveratrol for Improved Performance in the Elderly | memory impairment | Resveratrol (NPC161571) | NP level |
NCT00723268 | Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae | aphthous ulcer | Colchicine (NPC226941) | NP level |
NCT04400890 | Randomized Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol, a Plant Polyphenol, for COVID-19 | COVID-19 | Resveratrol (NPC161571) | NP level |
NCT02219906 | Resveratrol in Metabolic Syndrome: Effect on Platelet Hyper-reactivity and HDL Lipid Peroxidation | metabolic syndrome | Resveratrol (NPC161571) | NP level |
NCT02314208 | Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 | Spastic paraplegia | Resveratrol (NPC161571) | NP level |
NCT02060552 | Immune Molecular and Inflammatory Cytokines Dysfunction Analysis in Gout Patients With Different Urate Levels | gout | Colchicine (NPC226941) | NP level |
NCT05324423 | To Evaluate Drug Interactions Between XNW3009, Febuxostat, and Colchicine in Patients With Gout | gout | Colchicine (NPC226941) | NP level |
NCT00433576 | Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery | colorectal adenocarcinoma;malignant colon neoplasm;rectum cancer | Resveratrol (NPC161571) | NP level |
NCT01747174 | REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction | ST Elevation Myocardial Infarction | Adenosine (NPC156461) | NP level |
NCT04539873 | Impact of Colchicine in Hospitalized Colombian Patients With COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT05250596 | COLchicine On-admission to Reduce Inflammation in Acute Coronary Syndrome (COLOR-ACS) | acute coronary syndrome | Colchicine (NPC226941) | NP level |
NCT04264260 | Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment | cholangiocarcinoma | Colchicine (NPC226941) | NP level |
NCT02409537 | Effects of Dietary Antioxidants to Prevent Cardiovascular Disease | Hypercholesterolemia | Resveratrol (NPC161571) | NP level |
NCT01755949 | Colchicine and CRP in Atrial Fibrillation and AF Ablation | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT01677611 | Effects of Resveratrol in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Resveratrol (NPC161571) | NP level |
NCT05014061 | Adenosine's Effect on STunning Resolution in Acute Myocardial Infarction | Myocardial Ischemia | Adenosine (NPC156461) | NP level |
NCT00700297 | Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's Disease | Behcet's syndrome | Colchicine (NPC226941) | NP level |
NCT04603690 | Oral Curcumin, Quercetin and Vitamin D3 Supplements for Mild to Moderate Symptoms of COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04328480 | The ECLA PHRI COLCOVID Trial. Effects of Colchicine on Moderate/High-risk Hospitalized COVID-19 Patients. | COVID-19 | Colchicine (NPC226941) | NP level |
NCT01492114 | Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults. | inflammation | Resveratrol (NPC161571) | NP level |
NCT04916522 | The COlchicine HypERtENsion Trial | hypertension | Colchicine (NPC226941) | NP level |
NCT02582190 | COlchicine for the Prevention of Post Electrical Cardioversion Recurrence of AF | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT04449198 | Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1 | type 1 diabetes mellitus | Resveratrol (NPC161571) | NP level |
NCT02351622 | Caffeic Acid Tablets as a Second-line Therapy for ITP | autoimmune thrombocytopenic purpura | Caffeic Acid (NPC294902) | NP level |
NCT02063997 | Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patients | gout | Colchicine (NPC226941) | NP level |
NCT04762771 | Colchicine for the Treatment of Cardiac Injury in Hospitalized Patients With COVID-19 (COLHEART-19) | COVID-19 | Colchicine (NPC226941) | NP level |
NCT03093389 | Tolerability and Steady-state Pharmacokinetics of BIA 6-512 | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT00004748 | Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis | primary biliary cirrhosis | Colchicine (NPC226941) | NP level |
NCT02905799 | Resveratrol in Knee Osteoarthritis | osteoarthritis | Resveratrol (NPC161571) | NP level |
NCT04667780 | Study to Investigate the Treatment Effect of Colchicine in Patients With COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT01005121 | Colchicine for Diabetic Nephropathy | diabetic nephropathy | Colchicine (NPC226941) | NP level |
NCT00506883 | MPC-004 for the Treatment of an Acute Gout Flare | gout | Colchicine (NPC226941) | NP level |
NCT03094156 | Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT05472337 | Effect of Colchicine on Coronary Reperfusion in Patients With Acute Coronary Syndrome | acute coronary syndrome | Colchicine (NPC226941) | NP level |
NCT01690884 | Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake | coronary artery disease | Adenosine (NPC156461) | NP level |
NCT01985425 | Colchicine For Prevention of Perioperative Atrial Fibrillation in Patients Undergoing Thoracic Surgery Pilot Study | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT00781404 | Myocardial Protection With Adenosine During Primary Percutaneous Coronary Intervention in Pts With STEMI | acute myocardial infarction | Adenosine (NPC156461) | NP level |
NCT04666454 | BROKEN-SWEDEHEART-Optimized Pharmacological Treatment for Broken Heart (Takotsubo) Syndrome | Takotsubo cardiomyopathy | Adenosine (NPC156461) | NP level |
NCT01504854 | Resveratrol for Alzheimer's Disease | Alzheimer disease | Resveratrol (NPC161571) | NP level |
NCT02433925 | Resveratrol's Effects on Inflammation and Oxidative Stress in Chronic Kidney Disease | chronic kidney disease | Resveratrol (NPC161571) | NP level |
NCT02162303 | Colchicine in Vascular Inflammation Assessed With PET Imaging | vascular disease | Colchicine (NPC226941) | NP level |
NCT00654667 | Mechanisms of Metabolic Regulation of Resveratrol on Humans With Metabolic Syndrome | insulin resistance | Resveratrol (NPC161571) | NP level |
NCT02681913 | Adenosine as an Adjunct to Blood Cardioplegia | cardiomyopathy | Adenosine (NPC156461) | NP level |
NCT04492358 | Treatment for Moderate/Severe COVID-19 in a Fragile and Vulnerable Population, Admitted to a Geriatric Hospital Unit or in a Transicional Care Center | COVID-19 | Colchicine (NPC226941) | NP level |
NCT03236311 | A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI | coronary artery disease | Adenosine (NPC156461) | NP level |
NCT00098969 | UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants | neoplasm | Resveratrol (NPC161571) | NP level |
NCT03095092 | Effect of Food on BIA 6-512 (Trans-resveratrol) | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT00128453 | Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences | pericarditis | Colchicine (NPC226941) | NP level |
NCT05062486 | A Study to Evaluate the Safety and Efficacy of RQC for AMD | age-related macular degeneration | Resveratrol (NPC161571) | NP level |
NCT03048825 | Colchicine and Spironolactone in Patients With MI / SYNERGY Stent Registry | Non-ST Elevation Myocardial Infarction;ST Elevation Myocardial Infarction | Colchicine (NPC226941) | NP level |
NCT04420624 | COLchicine to Prevent Sympathetic Denervation After an Acute Myocardial Infarction | myocardial infarction | Colchicine (NPC226941) | NP level |
NCT03693781 | Colchicine for Amyotrophic Lateral Sclerosis | amyotrophic lateral sclerosis | Colchicine (NPC226941) | NP level |
NCT03091543 | Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT05175274 | Colchicine Use for Primary Prevention of Coronary Artery Disease | coronary artery disease | Colchicine (NPC226941) | NP level |
NCT00349921 | Clonidine Versus Adenosine to Treat Neuropathic Pain | pain | Adenosine (NPC156461) | NP level |
NCT00179010 | AMP as a Better Delivery System of Adenosine | ischemia | Adenosine (NPC156461) | NP level |
NCT02442921 | Colchicine for Diabetic Nephropathy Trial | diabetic nephropathy | Colchicine (NPC226941) | NP level |
NCT02523274 | Resveratrol and Exercise to Treat Functional Limitations in Late Life | aging | Resveratrol (NPC161571) | NP level |
NCT02549924 | Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Resveratrol (NPC161571) | NP level |
NCT01842399 | Resveratrol and Cardiovascular Health in the Elderly | hypertension | Resveratrol (NPC161571) | NP level |
NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Resveratrol (NPC161571);Ellagic Acid (NPC178134) | NP level |
NCT04542993 | Can SARS-CoV-2 Viral Load and COVID-19 Disease Severity be Reduced by Resveratrol-assisted Zinc Therapy | COVID-19;severe acute respiratory syndrome | Resveratrol (NPC161571) | NP level |
NCT02176460 | Colchicine for Symptom and Inflammation in Knee Osteoarthritis | osteoarthritis | Colchicine (NPC226941) | NP level |
NCT04130204 | Topical Application to Relieve Gout: Efficacy Trial & Safety (TARGETS) | gout | Colchicine (NPC226941) | NP level |
NCT02030977 | The Effects of Resveratrol Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Steatohepatitis | non-alcoholic fatty liver disease | Resveratrol (NPC161571) | NP level |
NCT01914081 | Resveratrol: A Potential Anti- Remodeling Agent in Heart Failure, From Bench to Bedside | dilated cardiomyopathy | Resveratrol (NPC161571) | NP level |
NCT00004368 | Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis | cirrhosis of liver | Colchicine (NPC226941) | NP level |
NCT04350320 | Trial to Study the Benefit of Colchicine in Patients With COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT05503225 | Colchicine Use in Intracranial Atherosclerotic Disease | atherosclerosis | Colchicine (NPC226941) | NP level |
NCT02867878 | Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo Syndrome | Takotsubo cardiomyopathy | Adenosine (NPC156461) | NP level |
NCT01075906 | Pharmacokinetics Study of Colchicine in Familial Mediterranean Fever (FMF) Patients | familial Mediterranean fever | Colchicine (NPC226941) | NP level |
NCT04363437 | COlchicine in Moderate-severe Hospitalized Patients Before ARDS to Treat COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT00128414 | Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) | pericarditis | Colchicine (NPC226941) | NP level |
NCT02261844 | Resveratrol and Human Hepatocyte Function in Cancer | liver cancer | Resveratrol (NPC161571) | NP level |
NCT01399008 | Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients | gout | Colchicine (NPC226941) | NP level |
NCT02500641 | Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout | gout | Colchicine (NPC226941) | NP level |
NCT05151614 | Adjuvant Use Of Colchicine With The Standard Therapy In Moderate And Severe Corona Virus Disease-19 Infection | COVID-19 | Colchicine (NPC226941) | NP level |
NCT03015831 | Effect of Low Dose ColchiciNe on the InciDence of POAF | atrial fibrillation | Colchicine (NPC226941) | NP level |
NCT04997551 | Double Blind Randomized Clinical Trial of Use of Colchicine Added to Standard Treatment in Hospitalized With Covid-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT02130440 | Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis | seasonal allergic rhinitis | Resveratrol (NPC161571) | NP level |
NCT02704494 | Resveratrol's Effects in Diabetic Nephropathy | diabetic nephropathy | Resveratrol (NPC161571) | NP level |
NCT04360980 | The Effects of Standard Protocol With or Without Colchicine in Covid-19 Infection | COVID-19 | Colchicine (NPC226941) | NP level |
NCT03021343 | Effect of Colchicine on the Incidence of Atrial Fibrillation in Open Heart Surgery Patients | cardiac arrhythmia | Colchicine (NPC226941) | NP level |
NCT04867226 | Effectiveness of Colchicine Among Patients With COVID-19 Infection | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04011618 | Effect of Ellagic Ácid on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion | metabolic syndrome | Ellagic Acid (NPC178134) | NP level |
NCT04375202 | Colchicine in COVID-19: a Pilot Study | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04392141 | Colchicine Plus Phenolic Monoterpenes to Treat COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
NCT03131583 | The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout | gout | Colchicine (NPC226941) | NP level |
NCT03091868 | Pharmacokinetics of Rising Single-doses of BIA 6-512 and Their Effect on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT00840489 | Efficacy of Long-term Ribavirin in Non-responders With Chronic Hepatitis C and Advanced Fibrosis | chronic hepatitis C virus infection | Colchicine (NPC226941) | NP level |
NCT04322565 | Colchicine Counteracting Inflammation in COVID-19 Pneumonia | coronavirus infectious disease;viral pneumonia | Colchicine (NPC226941) | NP level |
NCT03032965 | Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation | atrial fibrillation | Adenosine (NPC156461) | NP level |
NCT04500665 | Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine | chronic kidney disease | Colchicine (NPC226941) | NP level |
NCT04588441 | The ARCTIC Trial: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19 | acute respiratory distress syndrome | Adenosine (NPC156461) | NP level |
NCT00128427 | Study of Colchicine to Prevent the Postpericardiotomy Syndrome | Postpericardiotomy Syndrome | Colchicine (NPC226941) | NP level |
NCT03575572 | Colchicine in Postoperative Fontan Patients | heart disease | Colchicine (NPC226941) | NP level |
NCT00754819 | Targeting Inflammation in Acute Coronary Syndrome Using Colchicine | acute coronary syndrome | Colchicine (NPC226941) | NP level |
NCT00298636 | Dose-Response of Adenosine for Perioperative Pain | pain | Adenosine (NPC156461) | NP level |
NCT04516941 | CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19 | COVID-19;severe acute respiratory syndrome | Colchicine (NPC226941) | NP level |
NCT03933163 | Micronised Resveratrol as a Treatment for Friedreich Ataxia | Friedreich ataxia | Resveratrol (NPC161571) | NP level |
NCT02336633 | Resveratrol and Huntington Disease | Huntington disease | Resveratrol (NPC161571) | NP level |
NCT01932112 | Adenosine Effect on Persistent Pulmonary Vein Isolation Line Evaluation (APPLE Trial) | atrial fibrillation | Adenosine (NPC156461) | NP level |
NCT00612521 | Prophylactic Intra-coronary Adenosine to Prevent Post Coronary Artery Stenting Myonecrosis | coronary stenosis | Adenosine (NPC156461) | NP level |
NCT04724629 | Survival TRial Using CytoKines in COVID-19 (STRUCK Trial) | COVID-19 | Colchicine (NPC226941) | NP level |
NCT04008316 | Efficacy of Colchicine to Prevent Skin Relapses in Adult's IgA Vasculitis | vasculitis | Colchicine (NPC226941) | NP level |
NCT04324463 | Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial | COVID-19;severe acute respiratory syndrome | Colchicine (NPC226941) | NP level |
NCT03253913 | Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial | lymphangioleiomyomatosis | Resveratrol (NPC161571) | NP level |
NCT00845689 | Prevention of Liver Damage During Liver Surgery | neoplasm | Adenosine (NPC156461) | NP level |
NCT00819585 | A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study) | gout | Colchicine (NPC226941) | NP level |
NCT04326790 | The GReek Study in the Effects of Colchicine in Covid-19 cOmplications Prevention | COVID-19 | Colchicine (NPC226941) | NP level |
NCT02114892 | Effect of Resveratrol Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion | metabolic syndrome | Resveratrol (NPC161571) | NP level |
NCT00256334 | Resveratrol for Patients With Colon Cancer | malignant colon neoplasm | Resveratrol (NPC161571) | NP level |
NCT04367168 | Colchicine in Patients With Mild and Severe Coronavirus Disease | COVID-19 | Colchicine (NPC226941) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
PTGS1,KDR,ADORA2A,IGF1R,CNR1,PIK3CB,EGFR,MET,PIK3CA
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
CA14,MET,MMP9,ADORA1,MMP1,CA2,ADORA2A,PTGS1,ELAVL3
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
DPP4,MMP2,CNR2,MMP9,ADORA3,TRPA1,MMP1,ADORA2A,AKR1B1
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
THPO,GPR35,CA9,GMNN,MMP9,TRPA1,MMP1,CA12,CYP2D6
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
DPP4,MMP2,ESR1,ADORA3,CYP1B1,TRPA1,SMAD3,TUBB6,THPO
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MET,KDR,ADORA2A,IGF1R,MMP2,EGFR,MMP1,MMP9
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
PTGS2,CNR1,NFKB1,PTGS1,DPP4,INSR
NCT01677611,NCT02549924 |
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
MMP2,EGFR,MET,ESR1,SRC,MMP9,MMP1,KDR
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ADORA3,MMP1,MMP9,AKR1B1,PTGS1,CA2,PTGS2,NFKB1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
INSR,DPP4,SRC,NQO2,PTGS2,CA2,TUBB6,LMNA
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
PAX8,GPR35,CA9,SHH,MMP9,MMP1,CA2,CYP2D6
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
MET,CSNK2A1,EGFR,IGF1R,KDR,ADORA3
NCT02261844 |
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
DPP4,PTGS2,PTGS1,THPO
NCT04420624,NCT03156816,NCT00590070 |
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CYP3A4,PAX8,CA9,MMP9,MMP1,CA2,AKR1B1
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
DPP4,MET,SHH,CYP1B1,MMP1,CA12,ADORA1
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
CNR2,MMP9,INSR
MMP9,PTGS2,MMP1 |
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
KDR,EGFR,MET,HSPA1A,HSPA1B,MMP9
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
KDR,MET,SRC,PTGS2,PTGS1
NCT01564381 |
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
MET,PTGS2,PTGS1,INSR,KDR
NCT01504854 |
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
CA9,KDR,MMP9,MET,EGFR,MMP2
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CA9,GMNN,MMP9,TRPA1,MMP1,CA12
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
CNR2,GPR35,MET,PTGS2,ADORA3,CNR1
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
TRPA1,HSPA1B,HSPA1A,PTGS1,AKR1B1
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
ESR1,ADORA2A,PIK3CA,PIK3CB
NCT01481233 |
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
SRC,MMP1,MMP2,EGFR,IGF1R
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CNR1,CYP2D6,CA2,NQO2,CNR2
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
DPP4,INSR,KDR,CNR1,AKR1B1
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ADORA1,ESR1,ADORA2A,PTGS1,PTGS2
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
MET,ADORA2A,ADORA1,CA2,AKR1B1
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4,CNR1
NCT02219906,NCT04011618,NCT02114892 |
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
CYP3A4,PTGS1,PTGS2,CNR2,NFKB1
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
ADORA3,ADORA2A,CA2,ADORA1
NCT04705987 |
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT02366091,NCT03236311,NCT01690884,NCT05175274,NCT01593644
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
CA9,MMP9,PTGS2,TRPA1,MMP1
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
DPP4,NFKB1,MET,PTGS2,ADORA2A
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
SLC22A3,MET,CA9,SHH,MMP1
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
MMP2,GPR35,ADORA2A,EGFR,LMNA
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP3A4,CA2,CNR1,MET,CA12
|
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
HSPA1A,HSPA1B,IGF1R,SRC
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
ADORA2A,DPP4,MET,TEK
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NFKB1,ESR1,DPP4,INSR
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
KDR,IGF1R,INSR,SRC
|
NADisease Category: NADisease ICD-11 Code: NA |
MET
NCT00000577,NCT00580905,NCT01492114 |
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
EGFR,HSPA1A,HSPA1B,ADORA2A
|
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
HSPA1B,SRC,HSPA1A,KDR
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
PTGS1,PTGS2
NCT02905799,NCT02176460 |
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
PIK3CB,MET,EGFR,KDR
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
IGF1R,CNR1
NCT04500665,NCT02433925 |
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04324463,NCT04542993,NCT04516941,NCT04381936
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
MMP2,MMP9,TRPA1,CA12
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CA9,MMP9,MMP1,CA12
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CA9,MMP9,ADORA3,MMP1
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
SRC,KDR,MET
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
KDR,MET,EGFR
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
KDR,EGFR,MET
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
SRC,PIK3CA,DPP4
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
AKR1B1,ADORA2A
NCT02062190 |
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA12,CA14,CA2
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2,PTGS1,CA12
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
ESR1,NFKB1,SRC
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
PTGS1,PTGS2,NFKB1
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
ESR1,PTGS2,PTGS1
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
MET,SRC,KDR
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
NFKB1,DPP4,ADORA3
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
IGF1R,TEK,APEX1
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
SRC,HSPA1A,HSPA1B
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
SRC,PTGS2,PTGS1
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
EGFR,PTGS2,KDR
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
PTGS1,PTGS2,ESR1
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
SRC,EGFR
NCT00179010 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
ADORA2A
NCT04916522,NCT01842399 |
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
MET,KDR,EGFR
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
SMAD3,HSPA1A,HSPA1B
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
EGFR
NCT01123525,NCT00751491 |
Acute ST elevation myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41.0 |
NCT00284323,NCT01747174,NCT03048825
|
Acute ischaemic heart disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA4Z |
NCT05472337,NCT00754819,NCT05250596
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT00845689,NCT00098969,NCT05279690
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
POLH,HPGD
NCT04867252 |
Chronic kidney disease, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.Z |
NCT02442921,NCT01005121,NCT02704494
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
MET,MMP9,MMP1
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
IGF1R,ADORA3,ADORA2A
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
MMP9,TRPA1,DPP4
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
HSPA1A,MMP9,MMP1
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
MMP9,ADORA3,PTGS1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
NUAK1,CNR2,RECQL,MMP1,LMNA,APEX1,CSNK2A1,MMP2,SMN1,EGFR,SLC22A3,TEK,TDP1,THPO,PAX8,SRC,KDR,CSNK2A2,CA9,GMNN,ADORA1,TUBB6,CNR1,POLH,MET,TRPA1,CA12,AKR1B1,HSD17B10
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04756128,NCT04324463,NCT04472611,NCT04997551,NCT04724629,NCT04539873,NCT04867226,NCT04392141,NCT04762771,NCT04603690,NCT04355143,NCT04416334,NCT04326790,NCT04400890,NCT04363437,NCT05118737,NCT04516941,NCT04367168,NCT04359095,NCT04375202,NCT04350320,NCT04542993,NCT04360980,NCT04322682,NCT05151614,NCT04328480,NCT04667780,NCT04492358
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
APEX1,ADORA2A,CSNK2A1,PTGS2,PIK3CA,PTGS1,CA12,ESR1,EGFR,CA2,ADORA3,MET,IGF1R,TEK,CYP3A4,POLB,MMP9,HSPA1B,KDR,NQO2,PIK3CB,HSPA1A,NFKB1,SRC,CA14,CA9
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CNR2,HPGD,MMP9,RECQL,MMP1,LMNA,APEX1,DPP4,SMN1,EGFR,SLC22A3,TDP1,PAX8,SRC,KDR,CSNK2A2,CA9,GMNN,PTGS1,CNR1,GALNT2,POLH,MET,ADORA3,TRPA1,CA12
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
NUAK1,CA14,CNR2,SHH,PTGS2,RECQL,MMP1,LMNA,DPP4,MMP2,CYP1B1,ADORA2A,SLC22A3,TEK,PAX8,CA9,CA2,TUBB6,PTGS1,POLB,MET,ADORA3,TRPA1
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
NUAK1,CA14,CNR2,HPGD,SHH,MMP1,DPP4,MMP2,SMAD3,ADORA2A,SMN1,TEK,KDR,GMNN,PIK3CB,PTGS1,MET,SLC22A6,TRPA1,CA12,AKR1B1
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
CA14,SHH,MMP9,PTGS2,MMP1,DPP4,TDP1,PAX8,CA9,GMNN,CA2,ADORA1,PTGS1,GALNT2,POLB,MET,TRPA1,AKR1B1,ELAVL3,HSD17B10
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
NUAK1,MMP9,MMP1,LMNA,IGF1R,CSNK2A1,MMP2,SMAD3,PAX8,SRC,GPR35,CA9,GMNN,ADORA1,TUBB6,PTGS1,CNR1,TRPA1,AKR1B1,ELAVL3
|
Inherited coagulation factor deficiencyDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B14 |
PTGS2,PTGS1
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
MET,EGFR
|
VasculitisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A44 |
PTGS1
NCT04008316 |
Spinal painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84 |
PTGS1,PTGS2
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
ADORA2A
NCT02245932 |
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
MMP9,PTGS1
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
CA9,EGFR
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
ADORA2A,NFKB1
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
PTGS2,PTGS1
|
Urinary system diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC2Z |
PTGS1,PTGS2
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
PIK3CA
NCT00455416 |
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
MET,KDR
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
KDR,EGFR
|
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
SRC,KDR
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR,ADORA3
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
ESR1,CA2
|
Otitis mediaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA80-AB0Z |
PTGS2,PTGS1
|
Inflammatory spondyloarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA92 |
PTGS1,PTGS2
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
PTGS1,PTGS2
|
Gastrointestinal stromal tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5B |
KDR,SRC
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ADORA2A
NCT02130440 |
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
ADORA2A
NCT05503225 |
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
TEK,SRC
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
ADORA1,ADORA2A
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
PTGS2
NCT00000577 |
Joint painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME82 |
PTGS2,PTGS1
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
CNR1,CNR2
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
PTGS1,PTGS2
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
PTGS1,NFKB1
|
Reactive arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA11 |
PTGS1,PTGS2
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
CYP2D6,ADORA3
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
THPO,MMP9
|
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
MET
NCT03575572 |
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
SMN1,SMN2
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
NFKB1,SRC
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1,MMP2
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
NCT03446625 |
Metastatic malignant neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E09 |
HSPA1B,HSPA1A
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
SRC,EGFR
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1,IGF1R
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
MMP2
NCT00004368 |
Cardiac arrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC9Z |
ADORA1
NCT03021343 |
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
PTGS1
MMP1 |
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
NCT04322565 |
CardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43 |
NCT02681913,NCT01914081
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT00433576,NCT00256334
|
Friedreich ataxiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03.10 |
NCT01339884,NCT03933163
|
Stress-induced cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.5 |
NCT04666454,NCT02867878
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
MMP9
NCT02030977 |
Familial Mediterranean feverDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A60.0 |
NCT02602028,NCT01075906
|
Acute pericarditisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB20 |
NCT00128453,NCT00128414
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
MMP9,MMP1
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ADORA2A,SMAD3
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1,PTGS2
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
MMP9,MET
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
HPGD,SHH,MMP9,MMP1,APEX1,CSNK2A1,TDP1,CA9,GMNN,PIK3CB,CA2,ADORA1,POLH,MET,ESR1,ADORA3,CA12,ELAVL3
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
PAX8,GPR35,CA9,GMNN,MMP9,SLC22A6,MMP1,CA12,ADORA1,CNR1,SRC,CA9,GMNN,MMP9,MMP1,CA12,ADORA1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
CNR2,HPGD,MMP9,APEX1,CYP3A4,DPP4,CYP1B1,ADORA2A,NFKB1,CA9,GMNN,GALNT2,ADORA3,TRPA1,AKR1B1,HSD17B10
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
MET,CA12,ESR1,CA14,KDR,PIK3CB,CA9,PIK3CA,NQO2,IGF1R,SRC,CA2,EGFR,TEK
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
PTGS2,LMNA,DPP4,CYP1B1,KDR,CA9,GMNN,CA2,TUBB6,PTGS1,POLH,MET,ADORA3,CA12
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
MET,CA9,MMP9,ADORA3,TRPA1,CNR1,GPR35,CA9,MMP9,ADORA3,TRPA1,MMP1,CNR1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CA14,CNR1,THPO,CNR2,HPGD,GPR35,SHH,MMP9,PIK3CB,KDM4E,CA2,ADORA2A,ELAVL3
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SRC,PTGS2,ADORA2A,PTGS1,ADORA1
NCT03091543,NCT03093389,NCT03095092,NCT03097211,NCT03095105,NCT03094156,NCT03091868 |
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
NCT02500641,NCT02330796,NCT01399008,NCT02139046,NCT00819585,NCT01994226,NCT03131583,NCT02060552,NCT00506883,NCT02063997,NCT04130204,NCT05324423
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
NUAK1,CA12,IGF1R,SRC,MMP2,GPR35,GMNN,MMP9,MMP1,AKR1B1,CNR1
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
THPO,CNR2,ESR1,CA9,SHH,MMP9,TRPA1,MMP1,CA12,ADORA2A,ELAVL3
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
CNR1,CNR2,PTGS1,PTGS2,IGF1R,AKR1B1,INSR,PIK3CB
NCT00349921,NCT00298636 |
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT03015831,NCT01985425,NCT02582190,NCT04870424,NCT03905759,NCT03032965,NCT04160117,NCT01755949,NCT01932112,NCT05459974
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
CYP3A4,DPP4,HPGD,MET,CA9,GMNN,MMP9,MMP1,CA12,ADORA1
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
NFKB1
|
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
SRC
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
Inborn metabolism deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5C59 |
CA14
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AKR1B1
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
CNR1
|
Ataxic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03 |
PTGS1
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
CNR1
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
KDR
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
Lysosomal diseaseDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C56 |
INSR
|
Type-1/2 diabeteDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10-5A11 |
INSR
|
Radionuclide imagingDisease Category: NADisease ICD-11 Code: N.A. |
ADORA2A
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
EGFR
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
TEK
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
CNR2
|
Knee osteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
PTGS2
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
TRPA1
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB9Z |
MET
|
Ocular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D00-2D07 |
APEX1
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
CNR1
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ESR1
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
SRC
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
INSR
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
MET
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
PTGS1
|
LeiomyosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B58 |
SRC
|
Epidermal dysplasiasDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK90 |
SRC
|
Unspecific substance use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4Z |
ADORA2A
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
CNR1
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
Supraventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81 |
ADORA1
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Multiple structural anomalies syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F |
IGF1R
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
CNR2
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
|
Anorexia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B80 |
CNR1
|
Synovial sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5A |
SRC
|
Eye anterior segment structural developmental anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA11 |
PTGS1
|
Extraocular muscle disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C82 |
IGF1R
|
Cannabis use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C41 |
CNR1
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
|
Digestive organ benign neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E92 |
KDR
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ADORA1
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
SRC
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
IGF1R
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
CYP3A4
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR1
|
Metastatic digestive system neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D8Y |
SRC
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
SRC
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
EGFR
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT05062486
|
ParaplegiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB56 |
NCT02314208
|
Other specified malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NCT00433576
|
Oral aphthae or aphtha-like ulcerationDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01.10 |
NCT00723268
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT00840489
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00565188
|
Huntington diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01.10 |
NCT02336633
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
NCT04648917
|
Chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
NCT03743636
|
Postcardiotomy syndromeDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BE10 |
NCT00128427
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT04449198
|
LymphangioleiomyomatosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB07 |
NCT03253913
|
Diseases of coronary artery, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Z |
NCT00612521
|
Primary biliary cholangitis, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB96.1Z |
NCT00004748
|
Behçet diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A62 |
NCT00700297
|
Intracranial injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07 |
NCT05159219
|
Insulin-resistance syndromesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A44 |
NCT00654667
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT00433576
|
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT05014061
|
Acute non-ST elevation myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41.1 |
NCT03048825
|
Urogenital cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C95-2C9Z |
NCT05279690
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT02523274
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT04588441
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT03693781
|
CholangiocarcinomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH7M15 |
NCT04264260
|
Acute myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41 |
NCT00781404
|
VitreoretinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B78 |
NCT00370760
|
Ventricular tachycardiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC71.0 |
NCT04392362
|
Viral pneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.1 |
NCT04322565
|
Diseases of the circulatory system, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BE2Z |
NCT02162303
|
Immune thrombocytopenic purpuraDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64.10 |
NCT02351622
|
Chronic lymphocytic leukaemia or small lymphocytic lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82.0 |
NCT00714103
|
ConcussionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.0 |
NCT01321151
|
Age-associated cognitive declineDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.0 |
NCT01126229
|
HypercholesterolaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.0 |
NCT02409537
|
Non-alcoholic steatohepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92.1 |
PTGS2
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
SHH
|
Intrauterine growth restrictionDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA20.1 |
ADORA2A
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
HPGD
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
PTGS2
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
ADORA2A
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
CA14
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
MMP9
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
CNR1
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
MMP9
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
MET
|