Laxative
India; China; Russia; South Africa
Ingredient ID: NPC97181
Ingredient ID: NPC96769
Ingredient ID: NPC89124
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Ingredient ID: NPC122078
Ingredient ID: NPC11592
Ingredient ID: NPC112890
Ingredient ID: NPC111132
Ingredient ID: NPC107334
Ingredient ID: NPC100998
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
Cytochrome P450 | Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
Therapeutic Target | Enzyme | GFER | FAD-linked sulfhydryl oxidase ALR | P55789 | CHEMBL1741189 |
Therapeutic Target | Enzyme | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
Therapeutic Target | Enzyme | CES1 | Acyl coenzyme A:cholesterol acyltransferase | P23141 | CHEMBL2265 |
Therapeutic Target | Fatty acid binding protein family | FABP4 | Fatty acid binding protein adipocyte | P15090 | CHEMBL2083 |
Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
Therapeutic Target | Methyl-lysine/arginine binding protein | L3MBTL1 | Lethal(3)malignant brain tumor-like protein 1 | Q9Y468 | CHEMBL1287622 |
Therapeutic Target | Nuclear hormone receptor subfamily 1 | NR1H4 | Bile acid receptor FXR | Q96RI1 | CHEMBL2047 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR2 | Estrogen receptor beta | Q92731 | CHEMBL242 |
Therapeutic Target | Oxidoreductase | MAOB | Monoamine oxidase B | P27338 | CHEMBL2039 |
Therapeutic Target | Oxidoreductase | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | P14061 | CHEMBL3181 |
Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
Therapeutic Target | Protein Kinase | CSNK2A1 | Casein kinase II alpha | P68400 | CHEMBL3629 |
Therapeutic Target | Protein Kinase | MKNK2 | MAP kinase signal-integrating kinase 2 | Q9HBH9 | CHEMBL4204 |
Therapeutic Target | Protein Phosphatase | CDC25B | Dual specificity phosphatase Cdc25B | P30305 | CHEMBL4804 |
Therapeutic Target | Secreted protein | TTR | Transthyretin | P02766 | CHEMBL3194 |
Therapeutic Target | Secreted protein | THPO | Thrombopoietin | P40225 | CHEMBL1293256 |
Therapeutic Target | Serine protease | DPP4 | Dipeptidyl peptidase IV | P27487 | CHEMBL284 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HRH4 | Histamine H4 receptor | Q9H3N8 | CHEMBL3759 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HRH1 | Histamine H1 receptor | P35367 | CHEMBL231 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HRH3 | Histamine H3 receptor | Q9Y5N1 | CHEMBL264 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Surface antigen | F3 | Coagulation factor III | P13726 | CHEMBL4081 |
Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 662 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00469586 | Efficacy and Safety of Inhaled Insulin Compared to Metformin and Glimepiride in Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00909506 | Efficacy and Safety of Adjuvant Metformin for Operable Breast Cancer Patients | breast cancer | Metformin (NPC230775) | NP level |
NCT04867252 | Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00713830 | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Sulfonylurea | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00672386 | A Study of the Safety and Effectiveness of a R256918 in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05132439 | MetfOrmin BenefIts Lower Extremities With Intermittent Claudication | intermittent vascular claudication | Metformin (NPC230775) | NP level |
NCT01997775 | Metformin in Stage IV Lung Adenocarcinoma | non-small cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT01266486 | Effect of Metformin on Breast Cancer Metabolism | breast cancer | Metformin (NPC230775) | NP level |
NCT01245166 | A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03905941 | Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT02325401 | Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma | head and neck malignant neoplasia | Metformin (NPC230775) | NP level |
NCT01766778 | Early add-on Vildagliptin in Patients With Type 2 Diabetes Inadequately Controlled by Metformin | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04925063 | The Effect of Metformin in Patients With Newly Diagnosed mHSPC | metastatic prostate cancer | Metformin (NPC230775) | NP level |
NCT03833466 | Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) | esophageal squamous cell carcinoma | Metformin (NPC230775) | NP level |
NCT01717482 | Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer | non-small cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT00754403 | Efficacy of Pioglitazone and Fortamet Combination Therapy in Subjects With Type 2 Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01488552 | Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer | pancreatic carcinoma | Metformin (NPC230775) | NP level |
NCT00614120 | Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00598793 | Biphasic Insulin Aspart 30 in Type 2 Diabetes Failing OAD Therapy | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05042024 | Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis | periodontitis | Arginine (NPC226453) | NP level |
NCT00755287 | A Study of the Safety, Tolerability and Effect on Glycemic Control of Taspoglutide Versus Insulin Glargine in Insulin Naive Type 2 Diabetic Patients Inadequately Controlled With Metformin Plus Sulphonylurea. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02294006 | Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs | pancreatic neuroendocrine tumor | Metformin (NPC230775) | NP level |
NCT05236530 | Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir | malaria | Metformin (NPC230775) | NP level |
NCT01340664 | An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00961909 | A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00614055 | Comparison of Two NN5401 Formulations Versus Insulin Glargine, All in Combination With Metformin in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00918138 | Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02040376 | Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma | brain neoplasm | Metformin (NPC230775) | NP level |
NCT00543361 | Study MK0767 and Metformin in Type 2 Diabetic Patients (0767-020) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02587741 | Comparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens | diabetic retinopathy | Metformin (NPC230775) | NP level |
NCT00868790 | A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00860288 | Efficacy and Long-Term Safety of Vildagliptin as Add-on Therapy to Metformin in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00525330 | A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of KRP-104 in Patients With Type 2 Diabetes Inadequately Controlled on Metformin Alone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01890122 | Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02488564 | A Study of Liposomal Doxorubicin + Docetaxel + Trastuzumab + Metformin in Operable and Locally Advanced HER2 Positive Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT02810132 | Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure | systolic heart failure | Metformin (NPC230775) | NP level |
NCT04510194 | COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19) | COVID-19;severe acute respiratory syndrome | Metformin (NPC230775) | NP level |
NCT02244567 | Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT02019979 | Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC) | non-small cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT03981861 | Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT03039075 | Metformin SR Tablet (DuLeNing) and Glucophage in Patients With Type 2 Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05053841 | Implication of Metformin Plus Aromatase Inhibitor in Obese Postmenopausal Breast Cancer Women | breast cancer | Metformin (NPC230775) | NP level |
NCT01405118 | Effect Of CP-690,550 On The Pharmacokinetics Of Metformin In Healthy Volunteers | rheumatoid arthritis | Metformin (NPC230775) | NP level |
NCT01095666 | A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00349635 | A Controlled-Study on the Effect of a Combination of Fenofibrate and Metformin on Weight Loss and Weight Loss-Maintenance, in Obese Patients. | obesity | Metformin (NPC230775) | NP level |
NCT00974714 | L-arginine Effects on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
NCT03030300 | Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01528046 | Metformin in Children With Relapsed or Refractory Solid Tumors | brain neoplasm | Metformin (NPC230775) | NP level |
NCT01816659 | An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin | colorectal carcinoma | Metformin (NPC230775) | NP level |
NCT02274090 | 1% Metformin in Moderate and Severe Periodontitis | periodontitis | Metformin (NPC230775) | NP level |
NCT04414540 | Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients | head and neck squamous cell carcinoma | Metformin (NPC230775) | NP level |
NCT04616248 | In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors | breast carcinoma | Lysine (NPC112890) | NP level |
NCT01561482 | Study of Metformin With Simvastatin for Men With Prostate Carcinoma | prostate carcinoma | Metformin (NPC230775) | NP level |
NCT01442870 | Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy | cancer | Metformin (NPC230775) | NP level |
NCT03710343 | Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study | spastic cerebral palsy | Metformin (NPC230775) | NP level |
NCT02190838 | Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma | melanoma | Metformin (NPC230775) | NP level |
NCT00344734 | Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure | congestive heart failure | Arginine (NPC226453) | NP level |
NCT02440061 | Ghrelin and Beta Cell Function in Diabetes | type 2 diabetes mellitus | Arginine (NPC226453) | NP level |
NCT00184574 | Comparison of Biphasic Insulin Aspart 70/30, 50/50, and 30/70 in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04177303 | Incretin Hormones in Type 1 Diabetes Mellitus | type 1 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01210911 | Metformin Combined With Chemotherapy for Pancreatic Cancer | pancreatic carcinoma | Metformin (NPC230775) | NP level |
NCT02372656 | Simvastatin and Metformin in Chronic Periodontitis | periodontitis | Metformin (NPC230775) | NP level |
NCT00971295 | Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers | neuropathic pain | Metformin (NPC230775) | NP level |
NCT03068832 | Neoepitope-based Personalized Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors | brain neoplasm | Lysine (NPC112890) | NP level |
NCT01117584 | A Study to Evaluate the Effect of ASP1941 in Combination With Metformin in Adult Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02931253 | Metformin as an Upstream Therapy in Atrial Fibrillation | atrial fibrillation | Metformin (NPC230775) | NP level |
NCT02042495 | Endometrial Cancer Biomarker Changes Following Exposure to Metformin | endometrial cancer | Metformin (NPC230775) | NP level |
NCT02640534 | Investigation of Metformin in Patients With Castration Resistant Prostate Cancer in Combination With Enzalutamide vs. Enzalutamide Alone | prostate carcinoma | Metformin (NPC230775) | NP level |
NCT00295633 | A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not Controlled With TZD Therapy Alone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01087983 | Lapatinib With Sirolimus or Metformin | cancer | Metformin (NPC230775) | NP level |
NCT02780024 | Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBM | glioblastoma multiforme | Metformin (NPC230775) | NP level |
NCT00915772 | Treatment of Type 2 Diabetes With Linagliptin 2.5 mg Bid + Metformin 500 or 1000 mg Bid and Metformin 1000 mg Bid | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00631033 | DZX Mediated Insulin Suppression in Obese Men | obesity | Metformin (NPC230775) | NP level |
NCT03151772 | Bioavailability of Disulfiram and Metformin in Glioblastomas | glioblastoma multiforme | Metformin (NPC230775) | NP level |
NCT04607252 | Metformin Plus Megestrol Acetate as a Fertility-sparing Treatment in Patients With Atypical Endometrial Hyperplasia | endometrial hyperplasia | Metformin (NPC230775) | NP level |
NCT00770445 | Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus. | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02042664 | Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00701090 | A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00620191 | Metformin in Amnestic Mild Cognitive Impairment | Cognitive impairment | Metformin (NPC230775) | NP level |
NCT01989897 | Effect of HSA or Saline Diluent on Immunotherapy Extract Stability as Determined by Graded ID Skin Tests | allergic rhinitis | Histamine (NPC111132) | NP level |
NCT03446456 | Vasopressin and Pain Perception in the Brain | pain | Arginine (NPC226453) | NP level |
NCT00969566 | Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01042379 | I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer | angiosarcoma;triple-negative breast cancer | Metformin (NPC230775) | NP level |
NCT01804049 | Metformin and Muscle in Insulin-resistant Older Veterans | prediabetes syndrome | Metformin (NPC230775) | NP level |
NCT00466622 | Uterine Artery Blood Flow in Pregnant Women With PCOS Treated With Metformin | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01215331 | Gestational Diabetes: Insulin or Oral Hypoglycemic Agents? | gestational diabetes | Metformin (NPC230775) | NP level |
NCT00174642 | Opposing Step-by-step Insulin Reinforcement to Intensified Strategy | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02254512 | Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC) | carcinoma | Metformin (NPC230775) | NP level |
NCT01175473 | Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00449605 | A Glycemic Control Evaluation of Glimepiride Versus Rimonabant on Top of Metformin in Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02689843 | Effects of Cyproterone Compound-spironolactone, Metformin and Pioglitazone on Inflammatory Markers in PCOS | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT02402348 | Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis | head and neck malignant neoplasia | Metformin (NPC230775) | NP level |
NCT01380678 | Intralesional Bevacizumab Injection on Primary Pterygium | inflammation;pterygium | Histamine (NPC111132) | NP level |
NCT00830076 | A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03600363 | A Clinical Trial of Metformin in the Maintenance of Non-Hodgkin's Lymphoma Patients | diffuse large B-cell lymphoma;follicular lymphoma | Metformin (NPC230775) | NP level |
NCT00975286 | 24-week Treatment With Lixisenatide in Type 2 Diabetes Insufficiently Controlled With Metformin and Insulin Glargine | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00279240 | Life Style Modifications Prevents Type 2 Diabetes in Asian Indians | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00454233 | A Safety and Efficacy Study With YM543 in Type 2 Diabetes Mellitus Subjects | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04054973 | L-arginine Study for Persistent Symptoms of Schizophrenia | schizophrenia | Arginine (NPC226453) | NP level |
NCT00348725 | Acceptability of a Fixed Combination of Fenofibrate and Metformin | metabolic disease | Metformin (NPC230775) | NP level |
NCT02656017 | Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease | Autosomal dominant polycystic kidney disease | Metformin (NPC230775) | NP level |
NCT01881828 | Metformin Therapy for Overweight Adolescents With Type 1 Diabetes | type 1 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00106340 | Vildagliptin Compared to Glimepiride in Combination With Metformin in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03137186 | Repurposing Metformin as Anticancer Drug: in Advanced Prostate Cancer | prostate cancer | Metformin (NPC230775) | NP level |
NCT01840007 | Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma | metastatic melanoma | Metformin (NPC230775) | NP level |
NCT00734474 | A Study of LY2189265 Compared to Sitagliptin in Participants With Type 2 Diabetes Mellitus on Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01877564 | A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women | adenocarcinoma | Metformin (NPC230775) | NP level |
NCT02460354 | Metformin and Congenital Nephrogenic Diabetes Insipidus | diabetes insipidus | Metformin (NPC230775) | NP level |
NCT03204071 | Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic Periodontitis | periodontitis | Metformin (NPC230775) | NP level |
NCT03606967 | Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer | breast carcinoma | Lysine (NPC112890) | NP level |
NCT04209075 | Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber) | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00611884 | Comparison of Two NN1250 Formulations Versus Insulin Glargine, All in Combination With Metformin in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00630383 | Immunoregulation by Controlled Parasite Exposure in Multiple Sclerosis. | multiple sclerosis | Histamine (NPC111132) | NP level |
NCT00159536 | Metformin in Pregnant PCOS Women | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT02618824 | Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery | congenital heart disease | Histidine (NPC237812) | NP level |
NCT03956056 | Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy | pancreatic carcinoma | Lysine (NPC112890) | NP level |
NCT00316082 | Study of BMS-477118 as Monotherapy With Titration in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00110851 | Safety and Efficacy Study of PN2034 in Type 2 Diabetes Patients on Concomitant Rosiglitazone and Metformin (or Avandamet) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01578551 | Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma. | lung adenocarcinoma | Metformin (NPC230775) | NP level |
NCT01483560 | REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL) | type 1 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03086005 | Study to Assess the Effect of Metformin Supplementation on IVF Outcome in Patients With Polycystic Ovarian Syndrome. | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01396564 | Pioglitazone and Metformin in Diabetic Children | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04364750 | Biomarkers of Diet-microbiota Interactions in Irritable Bowel Syndrome | irritable bowel syndrome | Histidine (NPC237812) | NP level |
NCT04604678 | Pilot Study Into the Use of Metformin and LDN for Patients With COVID-19 | COVID-19 | Metformin (NPC230775) | NP level |
NCT01439555 | Endothelial Facilitation in Alzheimer's Disease | Alzheimer disease | Arginine (NPC226453) | NP level |
NCT01075282 | A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00345150 | Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls | hypertension | Arginine (NPC226453) | NP level |
NCT01677923 | Obesity in Children and Adolescents: Associated Risks and Early Intervention | obesity | Metformin (NPC230775) | NP level |
NCT03179254 | Type 2 Diabetes and Ambulatory Surgery Patients | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00842400 | A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects. | obesity | Metformin (NPC230775) | NP level |
NCT01126580 | A Study in Participants With Type 2 Diabetes Mellitus (AWARD-3) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02519543 | Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder | bipolar disorder | Metformin (NPC230775) | NP level |
NCT02981329 | Fetal Hemoglobin Induction Treatment Metformin | sickle cell anemia | Metformin (NPC230775) | NP level |
NCT02143050 | Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients | melanoma | Metformin (NPC230775) | NP level |
NCT02903511 | Feasibility Study of Metformin Therapy in ADPKD | Autosomal dominant polycystic kidney disease | Metformin (NPC230775) | NP level |
NCT02531308 | Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL) | diffuse large B-cell lymphoma | Metformin (NPC230775) | NP level |
NCT01292070 | Safety Evaluation of an Experimental Treatment, Intradermal Human Fcγ1-Fel d1 Fusion Protein (GFD), for Cat Allergy | allergic disease | Histamine (NPC111132) | NP level |
NCT00930579 | Pre-Surgical Study: Effect of Metformin on Breast Cancer Proliferation | breast cancer | Metformin (NPC230775) | NP level |
NCT00131664 | Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02149459 | Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy | brain neoplasm | Metformin (NPC230775) | NP level |
NCT00968812 | CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02472353 | Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT03086733 | Phase II Lung Metcore - Preoperative Metformin for Lung Cancer | non-small cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT00348712 | Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04899349 | Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant | breast cancer | Metformin (NPC230775) | NP level |
NCT01192139 | Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN) | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00056433 | Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
NCT00263276 | A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01783431 | Study of Vaccination With Poly-ICLC and Peptide-pulsed Dendritic Cells | melanoma | Lysine (NPC112890) | NP level |
NCT01920191 | Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma | neoplasm | Lysine (NPC112890) | NP level |
NCT01365091 | Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01459809 | Efficacy and Safety Comparison of Metformin/Glimepiride Combination Versus Each Compound Alone in New Diagnosed Type 2 Diabetes Patients | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01996696 | Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate | prostate adenocarcinoma | Metformin (NPC230775) | NP level |
NCT02063802 | Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children | obesity | Metformin (NPC230775) | NP level |
NCT00684528 | A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01292993 | A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04088448 | The Antidiabetic Metformin as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients | major depressive disorder | Metformin (NPC230775) | NP level |
NCT05262257 | Evaluation and Intervention of Cognitive Function in Patients With Diabetes Mellitus. | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00134433 | Endothelial Modulation for Angiogenic Therapy | coronary artery disease | Arginine (NPC226453) | NP level |
NCT02365597 | An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer | urogenital neoplasm | Metformin (NPC230775) | NP level |
NCT00479466 | Dose-Range Finding Study for MK0893 (0893-008) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00382096 | Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Naive Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04649502 | Metformin for the Treatment of Hidradenitis Suppurativa (HS) | hidradenitis suppurativa | Metformin (NPC230775) | NP level |
NCT01243385 | Metformin Hydrochloride as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Prostate Cancer | prostate cancer | Metformin (NPC230775) | NP level |
NCT03674385 | Efficacy of Vit E in PCOS Resistant to Clomiphene Citrate | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00613951 | Comparison of Two NN5401 Formulations Versus Biphasic Insulin Aspart 30, All in Combination With Metformin in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04945148 | Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide | glioblastoma multiforme | Metformin (NPC230775) | NP level |
NCT01089192 | Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fasting Conditions. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01340768 | Study to Compare Sitagliptin Versus Sulfonylurea Treatment During Ramadan Fasting in Patients With Type 2 Diabetes (MK-0431-262) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01215032 | Metformin in Castration-Resistant Prostate Cancer | prostate cancer | Metformin (NPC230775) | NP level |
NCT00399711 | Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00097500 | Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00414245 | Metformin for the Treatment of Diabetes in Pregnancy | gestational diabetes;type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02026869 | Vaginal Administration of Metformin in PCOS Patients. | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01087866 | Metformin Versus Insulin in the Treatment of Gestational Diabetes Mellitus | gestational diabetes | Metformin (NPC230775) | NP level |
NCT03617458 | Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension | pulmonary arterial hypertension | Metformin (NPC230775) | NP level |
NCT03651895 | Metformin to Reduce Airway Glucose in COPD Patients | chronic obstructive pulmonary disease | Metformin (NPC230775) | NP level |
NCT00855166 | Evaluation of the Effect of Dapagliflozin in Combination With Metformin on Body Weight in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00005107 | Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia | cirrhosis of liver | Arginine (NPC226453) | NP level |
NCT01779375 | RISE Pediatric Medication Study | prediabetes syndrome | Metformin (NPC230775) | NP level |
NCT02614339 | Effect of Adjunctive Metformin on Recurrence of Non-DM Colorectal Cancer Stage II High-risk/ III Colorectal Cancer | colorectal carcinoma | Metformin (NPC230775) | NP level |
NCT02956044 | Interaction of Bexagliflozin With Metformin, Glimepiride and Sitagliptin | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02437812 | Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma | ovarian carcinoma | Metformin (NPC230775) | NP level |
NCT00046462 | Determine Whether Glycemic Control is Different Between Lantus & a 3rd Oral Agent When Failure With Other Treatment | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01477060 | Modulation of Response to Hormonal Therapy With Lapatinib and/or Metformin in Patients With Metastatic Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT02580331 | 1% Metformin Gel in the Treatment of Class II Furcation Defects | periodontitis | Metformin (NPC230775) | NP level |
NCT01318135 | Long-term Safety Study of Alogliptin Used in Combination With Sulfonylurea or Metformin in Participants With Type 2 Diabetes in Japan | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01440127 | Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers | malignant colon neoplasm | Metformin (NPC230775) | NP level |
NCT03229057 | Comparing the Effects of Oral Contraceptive Pills Versus Metformin | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00121641 | Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01154348 | Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05394142 | A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS) | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT03824002 | Dulaglutide in Diabetic Patients, Relationship Between Arterial Stiffness, Endothelial Function, Clinical and Laboratory Variables | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00885378 | Efficacy and Safety Study of Saxagliptin + Metformin Immediate Release (IR) Versus Metformin IR Alone in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01135433 | A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Type 2 Diabetic Patients | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03379909 | Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer | urinary bladder cancer | Metformin (NPC230775) | NP level |
NCT02949700 | Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma | head and neck squamous cell carcinoma | Metformin (NPC230775) | NP level |
NCT01302145 | Drug to Drug Interaction Study With ASP1941 and Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04973891 | CANA/Met in Non-diabetic Women With PCOS | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT04865835 | A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia. | schizophrenia | Metformin (NPC230775) | NP level |
NCT05281926 | A Phase I, Open-label Study to Assess the Safety and Efficacy of Poly-ICLC Plus Nivolumab in Unresectable Hepatocellular Carcinoma Patients | hepatocellular carcinoma | Lysine (NPC112890) | NP level |
NCT00703755 | A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome. | metabolic syndrome | Metformin (NPC230775) | NP level |
NCT01779362 | RISE Adult Medication Study | prediabetes syndrome | Metformin (NPC230775) | NP level |
NCT04631536 | Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC | COVID-19 | Arginine (NPC226453) | NP level |
NCT01370707 | A Study to Evaluate the Efficacy and Safety of CJ-30001 and CJ-30002 in Type 2 Diabetes Mellitus Patients | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01310231 | A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT02644954 | Assessing the Efficacy and Safety of Metformin in Treatment of Moderate Psoriasis | psoriasis | Metformin (NPC230775) | NP level |
NCT00683735 | Quantification of the Dipeptidyl Peptidase (DPP)-4 Inhibition-mediated Enhancement of the Activity of the Entero-insular Axis | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05093959 | Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction Pilot Study | heart failure | Metformin (NPC230775) | NP level |
NCT01613755 | Metformin-Dipyridamole Interaction Trial | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00468039 | A Sub-study to LMF237A2302 to Assess the Effect of 24 Weeks Treatment With Initial Combination of Vildagliptin Plus Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00677339 | L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB) | pulmonary tuberculosis | Arginine (NPC226453) | NP level |
NCT00482729 | MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00714233 | Treatment of Adolescent Polycystic Ovary Syndrome (PCOS) | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00332488 | Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02186847 | Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer | bronchoalveolar adenocarcinoma;large cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT00200746 | Treatment of Alcohol-Related Hepatitis With Arginine | Hepatitis, Alcoholic | Arginine (NPC226453) | NP level |
NCT02967276 | Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma | multiple myeloma | Metformin (NPC230775) | NP level |
NCT00303537 | Metformin in Non-Alcoholic Fatty Liver Disease | Hepatic steatosis | Metformin (NPC230775) | NP level |
NCT01329016 | Glyburide and Metformin for Gestational Diabetes Mellitus (GDM) | gestational diabetes | Metformin (NPC230775) | NP level |
NCT03640949 | Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest | sudden cardiac arrest | Arginine (NPC226453) | NP level |
NCT01472367 | A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04249336 | Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH | allergic disease | Arginine (NPC226453) | NP level |
NCT03243851 | Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory Glioblastoma | glioblastoma multiforme | Metformin (NPC230775) | NP level |
NCT02815397 | DA-EPOCH-Rituximab/Metformin (RM) for Double Hit Lymphoma | diffuse large B-cell lymphoma | Metformin (NPC230775) | NP level |
NCT00917826 | Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies | lymphoma | Arginine (NPC226453) | NP level |
NCT01093794 | Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01710527 | BE Study of Metformin GSK 500mg | diabetic foot | Metformin (NPC230775) | NP level |
NCT00881530 | Empagliflozin (BI 10773) in Type Two Diabetes (T2D) Patients, Open Label Extension | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01808690 | EMERALD: Effects of Metformin on Cardiovascular Function in Adolescents With Type 1 Diabetes | type 1 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02018731 | L-citrulline and Metformin in Becker's Muscular Dystrophy | muscular dystrophy | Metformin (NPC230775) | NP level |
NCT01334125 | Adjunctive Metformin Therapy in Double Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02064374 | Effect of Dolutegravir on Metformin Pharmacokinetics in Healthy Adult Subjects | HIV infection | Metformin (NPC230775) | NP level |
NCT04764383 | Histaminergic Basis of Fatigue in Multiple Sclerosis | multiple sclerosis | Histidine (NPC237812) | NP level |
NCT02473094 | Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer | rectum cancer | Metformin (NPC230775) | NP level |
NCT02083692 | Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling | squamous cell carcinoma | Metformin (NPC230775) | NP level |
NCT02427581 | Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy | triple-negative breast cancer | Lysine (NPC112890) | NP level |
NCT04998032 | A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05373680 | Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression | chronic kidney disease | Metformin (NPC230775) | NP level |
NCT03204058 | Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis | periodontitis | Metformin (NPC230775) | NP level |
NCT02778776 | Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome | metabolic syndrome | Metformin (NPC230775) | NP level |
NCT05025488 | Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm | essential thrombocythemia;myelofibrosis | Lysine (NPC112890) | NP level |
NCT01627067 | Exemestane-RAD001-Metformin | breast cancer | Metformin (NPC230775) | NP level |
NCT00359112 | AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02696941 | SGLT2 Inhibitors and Metformin on Metabolism and Non-Alcoholic SteatoHepatitis | non-alcoholic fatty liver disease | Metformin (NPC230775) | NP level |
NCT02773927 | Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome | metabolic syndrome | Metformin (NPC230775) | NP level |
NCT02498522 | Effect of Metformin on Early Pregnancy Loss in Pregnant Women With Polycystic Ovarian Syndrome | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT03117517 | Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT03121677 | Personalized Tumor Vaccine Strategy and PD-1 Blockade in Patients With Follicular Lymphoma | follicular lymphoma | Lysine (NPC112890) | NP level |
NCT01064687 | A Study in Participants With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02662283 | Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy | IGA glomerulonephritis | Acetoside (NPC197316) | NP level |
NCT04742751 | An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer | prediabetes syndrome | Metformin (NPC230775) | NP level |
NCT02278965 | Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer | breast carcinoma in situ | Metformin (NPC230775) | NP level |
NCT00838903 | Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02275845 | Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus | gestational diabetes | Metformin (NPC230775) | NP level |
NCT00344916 | Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis | cirrhosis of liver | Arginine (NPC226453) | NP level |
NCT03259919 | Metformin Treatment of Pregnant Women With Polycystic Ovary Syndrome: a Pilot Study | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT03359239 | Atezolizumab Given in Combination With a Personalized Vaccine in Patients With Urothelial Cancer | urinary bladder cancer | Lysine (NPC112890) | NP level |
NCT00006136 | Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia | Beta-thalassemia | Arginine (NPC226453) | NP level |
NCT03108963 | L-carnitine and Metformin in Obese PCOS Women. | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01089166 | Study to Compare the Bioavailability of Extended Release Metformin HCl Tablet Versus Glucophage XR® Tablets in Healthy Human Volunteers Under Fasting Condition | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00820573 | Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00767000 | Dose Range Finding Study of MK-0941 in Patients With Type 2 Diabetes Mellitus on Insulin (MK-0941-007 AM3 EXT1 AM1)(TERMINATED) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00362440 | Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome | HIV-Associated Lipodystrophy Syndrome | Metformin (NPC230775) | NP level |
NCT00120146 | Glaser Obesity Study | obesity | Metformin (NPC230775) | NP level |
NCT00673465 | Effect of SCH 497079 on Metabolic Parameters and Influence of Race/Ethnic Origin on Therapeutic Response (Study P05338)(COMPLETED) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03076281 | Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery | oral squamous cell carcinoma | Metformin (NPC230775) | NP level |
NCT02279758 | A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors | neuroendocrine neoplasm | Metformin (NPC230775) | NP level |
NCT00063635 | Treatment of Nonalcoholic Fatty Liver Disease in Children (TONIC) | Hepatic steatosis | Metformin (NPC230775) | NP level |
NCT01368081 | Empagliflozin (BI 10773) Comprehensive add-on Study in Japanese Subjects With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02848508 | Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study | chronic kidney disease | Metformin (NPC230775) | NP level |
NCT02659306 | Metformin Immunotherapy in HIV Infection | HIV infection | Metformin (NPC230775) | NP level |
NCT01796678 | Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial | pain | Arginine (NPC226453) | NP level |
NCT00081328 | Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00387738 | Efficacy and Safety Study of TOLAMBA™ in Ragweed-Allergic Adults | seasonal allergic rhinitis | Histamine (NPC111132) | NP level |
NCT04201873 | Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma | glioblastoma multiforme | Lysine (NPC112890) | NP level |
NCT00328172 | Efficacy and Safety of 3 Doses of BI1356 (Linagliptin) in Type 2 Diabetes Patients | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01332071 | Avandamet Bioequivalence Study Brazil - Fed Administration | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04750135 | Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis | ulcerative colitis | Metformin (NPC230775) | NP level |
NCT01240759 | Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Metformin Therapy | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00754689 | Study of Rimonabant/Metformin Combinations to Investigate Diabetes (Blood Sugar) Control in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04300790 | Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients | breast cancer | Metformin (NPC230775) | NP level |
NCT00975052 | A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02895750 | Efficacity and Safety of Metformin XR in CKD Stage 1 to 3 | chronic kidney disease | Metformin (NPC230775) | NP level |
NCT00383578 | Efficacy and Safety of Vildagliptin Compared to Metformin in Elderly Drug Naive Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00052715 | Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
NCT00361868 | Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI | Disorder of lipid metabolism | Metformin (NPC230775) | NP level |
NCT00405665 | The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis | cystic fibrosis | Arginine (NPC226453) | NP level |
NCT03258723 | Diabetes Prevention With Lifestyle Intervention and Metformin Escalation | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01051011 | A Study to Compare Taspoglutide and Insulin Glargine in Insulin-Naïve Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin and Sulfonylurea Combination Therapy | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00111631 | A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03056274 | Metformin in Intrahepatic Cholestasis of Pregnancy | pregnancy | Metformin (NPC230775) | NP level |
NCT01071850 | A Study to Evaluate the Effect of ASP1941 in Adult Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02388178 | To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Study | dental caries | Arginine (NPC226453) | NP level |
NCT04055012 | Effects of Metformin on Low Back Pain | Low back pain | Metformin (NPC230775) | NP level |
NCT02506790 | Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT01383356 | Comparison of the Bioavailability of Metformin Between Medium Dose Linagliptin/Metformin Tablets and Medium Dose Glucophage Tablet Given With Linagliptin Tablet | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01603446 | L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome | MELAS | Arginine (NPC226453) | NP level |
NCT01864096 | The Metformin Active Surveillance Trial (MAST) Study | prostate cancer | Metformin (NPC230775) | NP level |
NCT00744367 | A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00537355 | An Evaluation of the Efficacy and Safety of TOLAMBA™ for Ragweed-Allergic Rhinitis in an Environmental Exposure Chamber | seasonal allergic rhinitis | Histamine (NPC111132) | NP level |
NCT00345605 | Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder | argininosuccinic aciduria | Arginine (NPC226453) | NP level |
NCT01381900 | A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02088034 | Intervention to Promote Weight Loss in Latinas At-risk for Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01234649 | Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM) | abnormal glucose tolerance;metabolic syndrome | Metformin (NPC230775) | NP level |
NCT01028391 | 30-Week Extension to an Initial Combination Study (24 Weeks in Duration) of Sitagliptin With Pioglitazone (0431-064) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04826692 | TEsting METformin Against Cognitive Decline in HD | Huntington disease | Metformin (NPC230775) | NP level |
NCT02283554 | Platelet Rich Fibrin With 1% Metformin Gel for Treatment of Intrabony Defects | periodontitis | Metformin (NPC230775) | NP level |
NCT00350779 | Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00263965 | ARAMIS: Actions of tesaglitazaR on fAt Metabolism and Insulin Sensitivity | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03862950 | A Trial of Metformin in Individuals With Fragile X Syndrome (Met) | fragile X syndrome;intellectual disability;Intellectual disability;neurobehavioral manifestations;sex chromosome disorder of sex development | Metformin (NPC230775) | NP level |
NCT00617240 | Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth | body weight gain | Metformin (NPC230775) | NP level |
NCT00575588 | 52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00427154 | Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00037869 | High Dose I-131 Metaiodobenzylguanidine(MIBG) for Metastatic Neuroendocrine Tumors | metastasis;neuroendocrine neoplasm | Guanidine (NPC20535) | NP level |
NCT01750567 | A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL | chronic lymphocytic leukemia | Metformin (NPC230775) | NP level |
NCT04121468 | A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children With Multiple Sclerosis | multiple sclerosis | Metformin (NPC230775) | NP level |
NCT00032487 | Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01589367 | Neoadjuvant Letrozole Plus Metformin vs Letrozole Plus Placebo for ER-positive Postmenopausal Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT03000218 | Evaluation of PK and Biomarkers After UDCA Administrations to Subjects Who Are Overweight and Have Liver Problems | Elevated hepatic transaminase;obesity | Metformin (NPC230775) | NP level |
NCT02291458 | L-arginine and Brown Adipose Tissue | Glucose intolerance | Arginine (NPC226453) | NP level |
NCT01068743 | Bioequivalence Study of Fixed Dose Combination of 2.5 mg Saxagliptin/850 mg Metformin Tablet Relative to 2.5 mg Onglyza and 850 mg Glucophage Tablets Co-Administered | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00899470 | Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (A) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00102466 | Vildagliptin Compared to Gliclazide in Combination With Metformin in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04068246 | The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Rheumatoid Arthritis Patients | rheumatoid arthritis | Metformin (NPC230775) | NP level |
NCT02061449 | Poly ICLC, Radiation, and Romidepsin for Advanced Cutaneous T Cell Lymphoma | Cutaneous T-cell lymphoma | Lysine (NPC112890) | NP level |
NCT00859898 | Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00789191 | Effect of Detemir and Sitagliptin on Blood Glucose Control in Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02823691 | The MetNET-2 Trial | neuroendocrine neoplasm | Metformin (NPC230775) | NP level |
NCT01632020 | Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth | colorectal neoplasm | Metformin (NPC230775) | NP level |
NCT01677897 | Impact of the Addition of Metformin to Abiraterone in Metastatic Prostate Cancer Patients | metastatic prostate cancer | Metformin (NPC230775) | NP level |
NCT00700817 | The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00353691 | Glimepiride vs Metformin as Monotherapy in Pediatric Subjects With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00157521 | L-Arginine in Pre-Eclampsia | preeclampsia | Arginine (NPC226453) | NP level |
NCT03681197 | Metformin Use and Clinical Pregnancy Rate in Women With Unexplained Infertility | infertility | Metformin (NPC230775) | NP level |
NCT03841591 | Maternal Weight Gain in Gestational Diabetes Controlled by Metformin Versus Insulin | gestational diabetes | Metformin (NPC230775) | NP level |
NCT01650506 | Study of Erlotinib and Metformin in Triple Negative Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT00856986 | The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00279045 | Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00333151 | Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04511416 | Preventing Cognitive Decline With Metformin | Mental deterioration | Metformin (NPC230775) | NP level |
NCT02945813 | SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy | prostate cancer | Metformin (NPC230775) | NP level |
NCT05215990 | Efficacy of Metformin for Sputum Conversion in Patients With Active Pulmonary Tuberculosis | tuberculosis | Metformin (NPC230775) | NP level |
NCT00432276 | Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes Mellitus | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04817787 | Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome | metabolic syndrome | Metformin (NPC230775) | NP level |
NCT01192152 | Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01980823 | Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT01106625 | The CANTATA-MSU Trial (CANagliflozin Treatment And Trial Analysis - Metformin and SUlphonylurea) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04581447 | Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04248998 | Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer | triple-negative breast cancer | Metformin (NPC230775) | NP level |
NCT00108615 | Effects of Insulin Sensitizers in Subjects With Impaired Glucose Tolerance | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03311308 | A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma | melanoma | Metformin (NPC230775) | NP level |
NCT05210504 | Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3 | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
NCT03047837 | A Randomized, 2x2 Factorial Design Biomarker Prevention Trial of Low-dose Aspirin and Metformin in Stage I-III Colorectal Cancer Patients. | malignant colon neoplasm | Metformin (NPC230775) | NP level |
NCT00961480 | A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00772174 | Efficacy and Safety Study of Pioglitazone Combined With Metformin on Metabolic Syndrome in Subjects With Type 2 Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00420511 | Beta-Cell Function and Sitagliptin Trial (BEST) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00379769 | RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04926155 | The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer | metastatic prostate cancer | Metformin (NPC230775) | NP level |
NCT00086502 | Pioglitazone Add-on Study in Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00327015 | A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00223717 | Treatment of Supine Hypertension in Autonomic Failure | hypertension | Arginine (NPC226453) | NP level |
NCT01111955 | Safety Study of BMS-823778 in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01485315 | Transfusion-requirements in Septic Shock Trial | septic shock | Adenine (NPC18335) | NP level |
NCT02562664 | Metformin Improves Clinical Pregnancy Rate in Polycystic Ovarian Syndrome Patients | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT02048761 | Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis | periodontitis | Metformin (NPC230775) | NP level |
NCT00425009 | Therapeutic Effects of Berberine in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00499707 | Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03722290 | Metformin in Children and Adults With Fragile X Syndrome | fragile X syndrome | Metformin (NPC230775) | NP level |
NCT00851903 | Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension Trial | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05426044 | Metformin as a Neuroprotective Therapy for Glaucoma - A Randomized Controlled Trial | glaucoma | Metformin (NPC230775) | NP level |
NCT04224051 | Metformin for Abdominal Aortic Aneurysm Growth Inhibition | Abdominal Aortic Aneurysm | Metformin (NPC230775) | NP level |
NCT01302002 | The Use of Metformin in Early Breast Cancer Patients Pre-Surgery | breast cancer | Metformin (NPC230775) | NP level |
NCT01037660 | Effects of Lipemia and Metformin on Endothelial Function | cardiovascular disease | Metformin (NPC230775) | NP level |
NCT00770835 | Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus. | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01981525 | A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome | Li-Fraumeni syndrome | Metformin (NPC230775) | NP level |
NCT03054519 | Improve PAD PERformance With METformin | peripheral arterial disease | Metformin (NPC230775) | NP level |
NCT00541775 | Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00086515 | Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04141163 | Metformin in Patients With Fragile X | fragile X syndrome | Metformin (NPC230775) | NP level |
NCT03863405 | Metformin Use in Rheumatoid Arthritis | rheumatoid arthritis | Metformin (NPC230775) | NP level |
NCT00571519 | Randomized, Double-blind, Active-controlled, Study of Rivoglitazone in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01874080 | Bioequivalence Study | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03200015 | Rituximab, Cyclophosphamide, Vincristine and Prednisone (R-CHOP) Plus Metformin in Diffuse Large-B-cell Lymphoma | diffuse large B-cell lymphoma | Metformin (NPC230775) | NP level |
NCT04615351 | A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes Mellitus | gestational diabetes | Metformin (NPC230775) | NP level |
NCT00058123 | Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
NCT03465345 | Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients | prostate cancer | Metformin (NPC230775) | NP level |
NCT03764605 | Metformin vs Tolvaptan for Treatment of Autosomal Dominant Polycystic Kidney Disease | Autosomal dominant polycystic kidney disease | Metformin (NPC230775) | NP level |
NCT04750902 | A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children | dental caries | Arginine (NPC226453) | NP level |
NCT04275713 | Altered Tumor Oxygenation by Metformin, a Potential Step in Overcoming Radiotherapy Resistance in LACC | cervical cancer | Metformin (NPC230775) | NP level |
NCT01465113 | Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus | Barrett's esophagus | Metformin (NPC230775) | NP level |
NCT05305898 | "MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome | acute coronary syndrome | Metformin (NPC230775) | NP level |
NCT04500756 | Limiting AAA With Metformin (LIMIT) Trial | Abdominal Aortic Aneurysm | Metformin (NPC230775) | NP level |
NCT03994744 | Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC | small cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT04852510 | Amelioration of Polycystic Ovary Syndrome Related Disorders by Supplementation of Thymoquinone and Metformin | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01885013 | Myocet + Cyclophosphamide + Metformin Vs Myocet + Cyclophosphamide in 1st Line Treatment of HER2 Neg. Metastatic Breast Cancer Patients | breast carcinoma | Metformin (NPC230775) | NP level |
NCT03679780 | The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction | cardiovascular disease | Arginine (NPC226453) | NP level |
NCT00121667 | Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01915550 | Metformin as Adjuvant to Insulin Therapy in Insulin-resistant Diabetes Mellitus With Pregnancy | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02394652 | The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial | cervical adenocarcinoma;squamous cell carcinoma | Metformin (NPC230775) | NP level |
NCT02672488 | Metformin Plus Sorafenib for Advanced HCC | hepatocellular carcinoma | Metformin (NPC230775) | NP level |
NCT00519480 | A Study To Assess The Safety And Tolerability Of GSK189075 When Given With A Total Daily Dose Of >/ 2000mg of Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00251953 | GALLANT 8 Tesaglitazar Add-on to Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00283816 | Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT05440591 | Effects of Dapagliflozin and Metformin on Vascular Function in Newly-Diagnosed Treatment-Naive Type 2 Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00099866 | Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00728351 | Efficacy and Safety of Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy (HbA1c 7.0-9.5%) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01023581 | Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00875394 | Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02115464 | Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy | lung cancer | Metformin (NPC230775) | NP level |
NCT01388764 | Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
NCT04113889 | Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00544518 | Impact of Benfluorex Versus Metformin on Glucose Control and Insulin Secretion in Chinese Type 2 Diabetic Patients | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01076075 | A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01188096 | A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | brain neoplasm | Lysine (NPC112890) | NP level |
NCT00513617 | Effectiveness of Arginine as a Treatment for Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
NCT01796028 | Metformin-Docetaxel Association in Metastatic Hormone-refractory Prostate Cancer | prostate adenocarcinoma | Metformin (NPC230775) | NP level |
NCT04767841 | The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis | osteoarthritis | Metformin (NPC230775) | NP level |
NCT01217892 | Evaluation of Dapagliflozin Taken Twice-daily | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04143282 | Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment | breast cancer | Metformin (NPC230775) | NP level |
NCT01357876 | Effect of Metformin on Gut Peptides , Bile Acids and Lipid Profiles in Type 2 Diabetics | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03162562 | The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer | ovarian carcinoma | Lysine (NPC112890) | NP level |
NCT02497638 | LIpitor and biGuanide to Androgen Delay Trial | prostate cancer | Metformin (NPC230775) | NP level |
NCT01797523 | A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma | endometrial cancer | Metformin (NPC230775) | NP level |
NCT00286442 | Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02990728 | Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial Cancer | endometrial cancer | Metformin (NPC230775) | NP level |
NCT00408577 | Prevention of Cardiac and Vascular Events in Patients With NGT/IGT. | cardiovascular disease | Arginine (NPC226453) | NP level |
NCT04939935 | Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD) | Autosomal dominant polycystic kidney disease | Metformin (NPC230775) | NP level |
NCT03184493 | Celebrex and Metformin for Postoperative Hepatocellular Carcinoma | liver cancer | Metformin (NPC230775) | NP level |
NCT00754988 | A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02755844 | Safety and Efficacy of Metronomic Cyclophosphamide, Metformin and Olaparib in Endometrial Cancer Patients | endometrial cancer | Metformin (NPC230775) | NP level |
NCT01911247 | Preoperative Window Study of Metformin for the Treatment of Endometrial Cancer | endometrial cancer | Metformin (NPC230775) | NP level |
NCT00814372 | Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00631488 | A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00069836 | Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01204775 | Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04170959 | The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC | non-small cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT00316758 | A Study to Evaluate the Long-Term Safety and Tolerability of GK Activator (2) in Patients With Type 2 Diabetes. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00722371 | MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00103857 | MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00268476 | Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy | prostate cancer | Metformin (NPC230775) | NP level |
NCT01211197 | Bioavailability of a Fixed Dose Combination Tablet With Empagliflozin (BI 10773) and Metformin Compared With the Monocomponents and Effect of Food on Bioavailability | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00280683 | Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma | asthma | Arginine (NPC226453) | NP level |
NCT00605475 | Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00067951 | A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03376620 | Role of Topical Putrescine (Fibrostat) for Prevention of Hypertrophic Scars in Mammoplasty Patients | severe cutaneous adverse reaction | Putrescine (NPC309330) | NP level |
NCT00063232 | Treating Nonalcoholic Steatohepatitis (NASH) With Metformin | Hepatitis | Metformin (NPC230775) | NP level |
NCT01205672 | Evaluation of the Molecular Effects of Metformin on the Endometrium in Patients With Endometrial Cancer | endometrial cancer | Metformin (NPC230775) | NP level |
NCT02461667 | Alendronate Compared to Metformin in Chronic Periodontitis | periodontitis | Metformin (NPC230775) | NP level |
NCT01137812 | The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00719472 | A Study of Rituximab Alternative Dosing Rate in Patients With Previously Untreated Diffuse Large B-cell or Follicular Non-Hodgkin's Lymphoma (RATE) | non-Hodgkins lymphoma | Histamine (NPC111132) | NP level |
NCT00792935 | A Study to Test MK-0941 in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-0941-017) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04691960 | A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging | glioblastoma multiforme | Metformin (NPC230775) | NP level |
NCT01287585 | Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy | hepatocellular carcinoma | Arginine (NPC226453) | NP level |
NCT01084486 | Effect of Treatment With Insulin Sensitizer on Arterial Properties, Metabolic Parameters and Liver Function in Patients With Nonalcoholic Fatty Liver Disease | non-alcoholic fatty liver disease | Metformin (NPC230775) | NP level |
NCT01106677 | The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00762957 | Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus. | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00948402 | PED/PEA-15 Protein, PCOS, Obesity, Insulin Sensitivity Indexes, Metformin, Oral Contraceptives | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00941382 | Sibutramine-metformin Combination Versus Sibutramine and Metformin Monotherapy in Obese Patients | obesity | Metformin (NPC230775) | NP level |
NCT01107717 | Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DM | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04220021 | Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD | frontotemporal dementia | Metformin (NPC230775) | NP level |
NCT02457286 | Improving Insulin Resistance To Treat Non-Alcoholic Fatty Liver Disease: A Pilot Study | non-alcoholic fatty liver disease | Metformin (NPC230775) | NP level |
NCT02308228 | Metformin to Augment Strength Training Effective Response in Seniors (MASTERS) | aging | Metformin (NPC230775) | NP level |
NCT01169779 | Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00337610 | Sitagliptin Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00617058 | Improving Metabolic Parameters of Antipsychotic Child Treatment With Ziprasidone, Aripiprazole, and Clozapine | body weight gain | Metformin (NPC230775) | NP level |
NCT02682121 | Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo | prediabetes syndrome | Metformin (NPC230775) | NP level |
NCT01305551 | BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00871936 | A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03320694 | Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus | gestational diabetes | Metformin (NPC230775) | NP level |
NCT01995032 | L-citrulline and Metformin in Duchenne's Muscular Dystrophy | muscular dystrophy | Metformin (NPC230775) | NP level |
NCT00376038 | Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05131828 | CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy | multiple sclerosis | Metformin (NPC230775) | NP level |
NCT00959101 | Comparison of Repaglinide and Metformin Combination Tablet Versus Repaglinide and Metformin as Separate Tablets in Healthy Volunteers | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01324180 | Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL) | acute lymphoblastic leukemia | Metformin (NPC230775) | NP level |
NCT00881725 | A Study of Pre-operative Metformin in Prostate Cancer | prostate cancer | Metformin (NPC230775) | NP level |
NCT00261352 | GALLANT 14 Tesaglitazar vs. Metformin and Fenofibrate | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04530747 | Metabolic Effects of Metformin Therapy in Obstructive Sleep Apnea | obstructive sleep apnea | Metformin (NPC230775) | NP level |
NCT01266018 | Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer | small cell lung carcinoma | Arginine (NPC226453) | NP level |
NCT01622257 | Cavitation Ultrasound in Treatment of Patients With PCOS | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00961857 | A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Concomitant Administration of Sitagliptin and Metformin as Individual Tablets (0431A-048) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00856284 | Efficacy and Safety of Alogliptin Plus Metformin Compared to Glipizide Plus Metformin in Patients With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00885352 | Sitagliptin (MK-0431) vs. Placebo in Patients With Inadequate Glycemic Control on Metformin With Pioglitazone (MK-0431-128) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02312661 | Study of Metformin With Carboplatin/Paclitaxel Chemotherapy in Patients With Advanced Ovarian Cancer | ovarian cancer | Metformin (NPC230775) | NP level |
NCT02629627 | Conjugated Linoleic Acid / Leucine Versus Metformin on Visceral Fat in Metabolic Syndrome | metabolic syndrome | Metformin (NPC230775) | NP level |
NCT00643851 | An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03479476 | A Trial of Metformin in Individuals With Fragile X Syndrome | fragile X syndrome;Intellectual disability;neurobehavioral manifestations;sex chromosome disorder of sex development | Metformin (NPC230775) | NP level |
NCT00763815 | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Pioglitazone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04148183 | Effect of Metformin and Rosiglitazone Over no Diabetic With Metabolic Syndrome Patients. | insulin resistance | Metformin (NPC230775) | NP level |
NCT01775176 | Effect of Weight & Insulin Sensitivity on Reproductive Function in PCOS: Studies in Skeletal Muscle & Adipose | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01733459 | Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS) | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT04559308 | The Effect of Metformin on Breast Cancer Patients | breast cancer | Metformin (NPC230775) | NP level |
NCT00374907 | A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05457959 | Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant | glioma | Lysine (NPC112890) | NP level |
NCT00698230 | Safety and Efficacy of INCB013739 Plus Metformin Compared to Metformin Alone on Glycemic Control in Type 2 Diabetics | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00318461 | To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01076088 | Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00960661 | A Trial Comparing Two Therapies: Basal Insulin/Glargine, Exenatide and Metformin Therapy (BET) or Basal Insulin/Glargine, Bolus Insulin Lispro and Metformin Therapy (BBT) in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT05183204 | Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma | glioblastoma multiforme | Metformin (NPC230775) | NP level |
NCT01842139 | Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission | acute myeloid leukemia | Lysine (NPC112890) | NP level |
NCT00798161 | Safety and Efficacy of Linagliptin (BI 1356) Plus Metformin in Type 2 Diabetes, Factorial Design | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03861767 | REMAP Trial for Optimizing Surgical Outcomes at UPMC | aging | Metformin (NPC230775) | NP level |
NCT03618654 | Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma | oral squamous cell carcinoma;oropharynx squamous cell carcinoma | Metformin (NPC230775) | NP level |
NCT03017833 | Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers | neoplasm | Metformin (NPC230775) | NP level |
NCT00137124 | L-Arginine Metabolism in Essential Hypertension | essential hypertension | Arginine (NPC226453) | NP level |
NCT03006172 | To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT02848950 | The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows | infertility | Metformin (NPC230775) | NP level |
NCT03848533 | Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes | prediabetes syndrome | Metformin (NPC230775) | NP level |
NCT03713801 | Impact of Metformin on Immunity | aging | Metformin (NPC230775) | NP level |
NCT01217073 | A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02844803 | Study of Metformin and S. Baicalensis Combination Therapy in Type 2 Diabetes Mellitus Patients | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01725126 | To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes | obesity | Metformin (NPC230775) | NP level |
NCT01462266 | Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04345705 | Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma | mesothelioma | Lysine (NPC112890) | NP level |
NCT01581814 | Effects of Drospirenone-ethinylestradiol and/or Metformin on Cardiovascular Risk in Hyperinsulinemic Women With Polycystic Ovary Syndrome | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT03670043 | Tolerance & Responsiveness Improvement for Metformin (TRIM) | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00892073 | Hypothalamic Obesity Following Craniopharyngioma Surgery: A Pilot Trial of Combined Metformin and Diazoxide Therapy | obesity | Metformin (NPC230775) | NP level |
NCT00715624 | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04792749 | Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer | endometrial cancer | Metformin (NPC230775) | NP level |
NCT01336322 | Metformin and Sitagliptin in Women With Previous Gestational Diabetes | prediabetes syndrome | Metformin (NPC230775) | NP level |
NCT03072485 | Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers | aging | Metformin (NPC230775) | NP level |
NCT00266253 | A Study of GK Activator (2) in Patients With Type 2 Diabetes Mellitus Treated With a Stable Dose of Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02017249 | Efficacy Study of Oral Arginine to Improve Immune Function in Glioblastoma Multiforme | glioblastoma multiforme | Arginine (NPC226453) | NP level |
NCT00349128 | Fenofibrate in Dyslipidemia and Metformin-Controlled Diabetes | metabolic disease | Metformin (NPC230775) | NP level |
NCT02028221 | Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk | breast cancer | Metformin (NPC230775) | NP level |
NCT02929888 | Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate in STEMI Patients | acute myocardial infarction | Lysine (NPC112890) | NP level |
NCT03192293 | Metformin and Simvastatin in Addition to Fulvestrant | breast cancer | Metformin (NPC230775) | NP level |
NCT00000620 | Action to Control Cardiovascular Risk in Diabetes (ACCORD) | atherosclerosis;coronary artery disease;Hypercholesterolemia;hypertension;type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00698789 | Evaluate the Safety and Tolerability of INCB019602 When Administered With Metformin in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01482286 | Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01638676 | A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients | melanoma | Metformin (NPC230775) | NP level |
NCT04050098 | Bioequivalence Study for Gemigliptin/Metformin 50/1000 mg and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg. | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02447874 | Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
NCT04196868 | Methotrexate and Metformin in Rheumatoid Arthritis Patients | rheumatoid arthritis | Metformin (NPC230775) | NP level |
NCT05470998 | L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity | sickle cell anemia | Arginine (NPC226453) | NP level |
NCT01318109 | Efficacy and Safety of Alogliptin Used Combination With Metformin in Participants With Type 2 Diabetes in Japan | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02819869 | The Combination Effect of Statin Plus Metformin on Relapse-free | hepatocellular carcinoma | Metformin (NPC230775) | NP level |
NCT00272064 | ELEONOR STUDY: Insulin Glulisine in Type 2 Diabetes Mellitus. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01685762 | Metformin for the Treatment of Endometrial Hyperplasia | endometrial hyperplasia | Metformin (NPC230775) | NP level |
NCT00971243 | Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04972396 | ALT-801 DDI Study in Healthy Volunteers | non-alcoholic steatohepatitis | Metformin (NPC230775) | NP level |
NCT03008551 | Empagliflozin vs Metformin in PCOS | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00528879 | A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02129075 | A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma | cutaneous melanoma | Lysine (NPC112890) | NP level |
NCT01607879 | Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation | prostate cancer | Arginine (NPC226453) | NP level |
NCT00344851 | Exenatide and Metformin Therapy in Overweight Women With PCOS | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT01725490 | The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study | Familial adenomatous polyposis | Metformin (NPC230775) | NP level |
NCT00313313 | A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00971659 | Adjunctive Therapy of Exenatide or Sitagliptin to Insulin Glargine in Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01046500 | Myo-inositol Versus Metformin Administration in Post-menopausal Women With Metabolic Syndrome | metabolic syndrome | Metformin (NPC230775) | NP level |
NCT01324115 | NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors | neoplasm | Arginine (NPC226453) | NP level |
NCT01089179 | Bioequivalence Study of Metformin Hydrochloride Extended Release 500 mg Tablet Versus Glucophage XR® 500 mg Tablet in Healthy Volunteers Under Fed Conditions | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04839237 | The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients | obesity | Metformin (NPC230775) | NP level |
NCT00038727 | Diabetes Prevention Program Outcomes Study | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00699036 | Rosiglitazone Versus Rosiglitazone and Metformin Versus Rosiglitazone and Avandia in the Treatment of Nonalcoholic Steatohepatitis (NASH) | non-alcoholic steatohepatitis | Metformin (NPC230775) | NP level |
NCT01733836 | Prostate Cancer Active Surveillance Metformin Trial | prostate cancer | Metformin (NPC230775) | NP level |
NCT00690456 | Effect of Rimonabant and Metformin Combination on Glycemic Control in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01289119 | Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00616304 | Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
NCT00401973 | Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With Olanzapine | schizoaffective disorder;schizophrenia | Metformin (NPC230775) | NP level |
NCT00047983 | Omega-3 Fatty Acids That Affect the Immune System in Kidney Transplant Patients | kidney disease | Arginine (NPC226453) | NP level |
NCT02506777 | Neoadjuvant FDC With Melatonin or Metformin for Locally Advanced Breast Cancer. | breast cancer | Metformin (NPC230775) | NP level |
NCT01529593 | Temsirolimus in Combination With Metformin in Patients With Advanced Cancers | cancer | Metformin (NPC230775) | NP level |
NCT01566799 | Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer | neoplasm | Metformin (NPC230775) | NP level |
NCT00763451 | GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00727857 | Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus. | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03477162 | Metformin Pharmacology in Human Cancers: A Proof of Principle Study | neoplasm of thorax | Metformin (NPC230775) | NP level |
NCT05349474 | Metformin Treatment in Progressive Multiple Sclerosis | primary progressive multiple sclerosis;secondary progressive multiple sclerosis | Metformin (NPC230775) | NP level |
NCT00331851 | Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02882217 | Study to Assess Pharmacokinetics, Safety, and Tolerability of XC-8 | asthma | Histamine (NPC111132) | NP level |
NCT05243654 | Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy | leprosy | Metformin (NPC230775) | NP level |
NCT05468554 | Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer | thyroid cancer | Metformin (NPC230775) | NP level |
NCT01353391 | Metformin in Women With Type 2 Diabetes in Pregnancy Trial | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00481663 | A Study of Different Doses of Sitagliptin (MK-0431) in Participants With Type 2 Diabetes Mellitus (MK-0431-014) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02045290 | Insulin Clamp Ancillary Study for Assessment of Insulin Resistance | type 1 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02593097 | Metformin for the Prevention of Episodic Migraine (MPEM) | migraine disorder | Metformin (NPC230775) | NP level |
NCT01142219 | L-Arginine and Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
NCT01112722 | Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis | osteoarthritis, knee | Histamine (NPC111132) | NP level |
NCT01719133 | Skin Prick Tests With AllerT in Subjects Allergic to Birch Pollen | allergic rhinitis | Histamine (NPC111132) | NP level |
NCT03580122 | The Effect of Arginine on Classic Galactosemia | classic galactosemia | Arginine (NPC226453) | NP level |
NCT01464437 | AMG 151 Amgen Protocol Number 20100761 | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03490019 | Treatment of Bardet-Biedl-Syndrome With Metformin for Evaluation of a Possible Visual Improvement | Bardet-Biedl syndrome;blindness (disorder) | Metformin (NPC230775) | NP level |
NCT00676338 | Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04536805 | Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin | prostate cancer | Metformin (NPC230775) | NP level |
NCT00960076 | An 18 Week Efficacy and Safety Study of Saxagliptin and Metformin XR Combination in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01046422 | Safety Study of BMS-770767 in Subjects With Type 2 Diabetes | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03266965 | Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach | multiple sclerosis | Histidine (NPC237812) | NP level |
NCT05298670 | Drug Repurposing Using Metformin for Improving the Therapeutic Outcome in Multiple Sclerosis Patients | multiple sclerosis | Metformin (NPC230775) | NP level |
NCT02437656 | Combination of Metformin to Neoadjuvant Radiochemotherapy in the Treatment of Locally Advanced Rectal Cancer (METCAP). | rectum cancer | Metformin (NPC230775) | NP level |
NCT00375388 | The HOME Trial: Hyperinsulinaemia: the Outcome of Its Metabolic Effects, a Randomized Controlled Trial | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01864681 | Combination of Metformin With Gefitinib to Treat NSCLC | non-small cell lung carcinoma | Metformin (NPC230775) | NP level |
NCT01034111 | A Local Experiential Study With Sitagliptin (an Antihyperglycemic Drug) in 30 Patients With Type 2 Diabetes Mellitus (0431-178) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02360059 | Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT04428086 | A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects. | neoplasm | Metformin (NPC230775) | NP level |
NCT01926769 | A Phase II Study to Determine the Safety and Efficacy of Second-line Treatment With Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the Second Line Threatment of Advanced Colorectal Cancer | colorectal adenocarcinoma | Metformin (NPC230775) | NP level |
NCT00396357 | Efficacy/Safety of Vildagliptin and Metformin Combination Therapy in Patients With Type 2 Diabetes Not Well Controlled With Metformin Alone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01434186 | A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00789035 | 12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02614859 | Bicalutamide With or Without Metformin for Biochemical Recurrence in Overweight or Obese Prostate Cancer Patients | prostate carcinoma | Metformin (NPC230775) | NP level |
NCT00924573 | Comparative Study of HOE490 O (Glimepiride and Metformin) Compared With Placebo on Top of Glimepiride | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00707031 | GLP-1 Receptor Agonist Lixisenatide Versus Exenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00712673 | GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02285855 | Metformin in Non Small Cell Lung Cancer (NSCLC) | lung cancer | Metformin (NPC230775) | NP level |
NCT03053544 | Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer | rectum cancer | Metformin (NPC230775) | NP level |
NCT03378297 | IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC | ovarian cancer | Metformin (NPC230775) | NP level |
NCT00262730 | Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM | glioblastoma multiforme | Lysine (NPC112890) | NP level |
NCT00743002 | A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01204294 | Comprehensive Add on Study in Japan | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03135301 | Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome | infertility | Metformin (NPC230775) | NP level |
NCT01068730 | Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00839527 | A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00097279 | Comparison of Biphasic Insulin Aspart 70/30 With Anti-Diabetic Drugs in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01002807 | Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02756117 | The Effect of Acute Lysine Administration on α-aminoadipic Acid | prediabetes syndrome | Lysine (NPC112890) | NP level |
NCT00528372 | A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03349775 | Cardiometabolic Disease and Pulmonary Hypertension | obesity | Metformin (NPC230775) | NP level |
NCT04535427 | Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Arginine (NPC226453) | NP level |
NCT03861416 | "Unifuzol®" in Patients With Peripheral Arterial Disease | peripheral arterial disease | Arginine (NPC226453) | NP level |
NCT01068717 | Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01095653 | A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02484209 | DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study) | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00783744 | Insulin Glargine Combination Therapies in Type II Diabetics | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03166254 | Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung Cancer | non-small cell lung carcinoma | Lysine (NPC112890) | NP level |
NCT00986609 | MUC1 Vaccine for Triple-negative Breast Cancer | inflammatory breast carcinoma;triple-negative breast cancer | Lysine (NPC112890) | NP level |
NCT04098666 | Metformin in Alzheimer's Dementia Prevention | Cognitive impairment | Metformin (NPC230775) | NP level |
NCT00087516 | Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-021) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01620593 | Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate Cancer | prostate cancer | Metformin (NPC230775) | NP level |
NCT00976937 | 24-week Study Comparing Lixisenatide to Sitagliptin as add-on to Metformin in Obese Type 2 Diabetic Patients Younger Than 50 Years | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00147368 | Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
NCT01814748 | A Study of the Safety and Efficacy of Omarigliptin (MK-3102) in ≥18 and <45 Year-Old Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control (MK-3102-028) | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04780854 | Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN) | peripheral neuropathy | Metformin (NPC230775) | NP level |
NCT01296412 | Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02086526 | Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET) | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT02022007 | Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT02516085 | Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin | Duchenne muscular dystrophy | Arginine (NPC226453);Metformin (NPC230775) | NP level |
NCT04530058 | The Effects of Metformin on Morbidity and Mortality in Elderly Patients | burn | Metformin (NPC230775) | NP level |
NCT02744820 | Multiple Ascending Dose Study of GMC-252-L-Lys Salt in Healthy Subjects and Type 2 Diabetics | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
NCT00809536 | Investigation Of How PD 0332334 And Metformin Are Eliminated From The Body When They Are Administered At The Same Time | generalized anxiety disorder | Metformin (NPC230775) | NP level |
NCT03238495 | Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer | breast cancer | Metformin (NPC230775) | NP level |
NCT02249910 | Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy Subjects | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT04264897 | Antecedent Metabolic Health and Metformin Aging Study | aging;insulin resistance | Metformin (NPC230775) | NP level |
NCT01089205 | Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fed Conditions. | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01167738 | Combination Chemotherapy With or Without Metformin Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer | pancreatic carcinoma | Metformin (NPC230775) | NP level |
NCT03088345 | Early Use of Vasopressin in Post-Fontan Management | congenital heart disease | Arginine (NPC226453) | NP level |
NCT02946996 | Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy | prostate cancer | Metformin (NPC230775) | NP level |
NCT00900146 | Dose Finding, Safety and Efficacy of Monthly Subcutaneous Canakinumab Administration in Metformin Monotherapy Treated Type 2 Diabetic Patients | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00661362 | Evaluate Efficacy and Safety of Saxagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT01263041 | Effect of L-arginine and Glutamine on Preterm | Sepsis | Arginine (NPC226453) | NP level |
NCT02684578 | Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD | atrophic macular degeneration | Metformin (NPC230775) | NP level |
NCT03889795 | Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors | pancreatic carcinoma | Metformin (NPC230775) | NP level |
NCT01059825 | Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02719756 | Effect of SGLT-2 Inhibitor Dapagliflozin on Glycemic Variability in Patients With Diabetes Mellitus Type 2 | diabetes mellitus | Metformin (NPC230775) | NP level |
NCT03651531 | Comparison of Insulin Alone to Insulin With Metformin to Treat Gestational Diabetes Mellitus | gestational diabetes | Metformin (NPC230775) | NP level |
NCT00901979 | A 12 Week Study in Patients With Type 2 Diabetes Mellitus (T2DM) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00151411 | Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS) | polycystic ovary syndrome | Metformin (NPC230775) | NP level |
NCT00362323 | Fenofibrate and Metformin Fixed Combination vs Metformin - FAME METFO | metabolic disease | Metformin (NPC230775) | NP level |
NCT01106690 | The CANTATA-MP Trial (CANagliflozin Treatment and Trial Analysis - Metformin and Pioglitazone) | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT00571766 | Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
NCT01352026 | Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH) | pulmonary arterial hypertension | Metformin (NPC230775) | NP level |
NCT00627445 | Effect of Biphasic Insulin Aspart 50 on Blood Glucose Control in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Metformin (NPC230775) | NP level |
NCT02360618 | Metformin and Simvastatin Use in Bladder Cancer | urinary bladder cancer | Metformin (NPC230775) | NP level |
NCT04416269 | Oral Anti Diabetic Agents in the Hospital | diabetes mellitus | Metformin (NPC230775) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT03151772,NCT02017249,NCT04945148,NCT02780024,NCT04201873,NCT03243851,NCT05183204,NCT00262730,NCT04691960
|
Diabetes mellitus arising in pregnancyDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA63.2 |
NCT03651531,NCT01329016,NCT04615351,NCT03841591,NCT02275845,NCT00414245,NCT01215331,NCT03320694,NCT01087866
|
Periodontal diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0C |
NCT03204071,NCT05042024,NCT02283554,NCT02461667,NCT02048761,NCT02580331,NCT03204058,NCT02274090,NCT02372656
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
NR1I2,PSMB5,HRH3,CYP19A1,XDH,AKR1B10,FABP5,ALOX15,DPP4
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ACHE,CDC25B,BLM,HRH2,XDH,TTR,FABP5,PTPRC,DPP4
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NFKB1,HRH1,HRH4
NCT04068246,NCT01405118,NCT04196868,NCT04535427,NCT03863405 |
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ESR2,HRH1,HRH4,HRH3
NCT01719133,NCT01989897,NCT00387738,NCT00537355 |
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NFKB1
HRH4 NCT05131828,NCT04121468,NCT00630383,NCT04764383,NCT03266965,NCT05298670 |
Intermediate hyperglycaemia, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.Z |
NCT02756117,NCT01779375,NCT04742751,NCT01804049,NCT01336322,NCT02682121,NCT03848533,NCT01779362
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
ACHE,BLM,HRH3,HRH1,OR51E2,XDH,TTR,FABP5
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
NCT03166254,NCT01864681,NCT01717482,NCT04170959,NCT01997775,NCT02019979,NCT03086733
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
NCT02042495,NCT01797523,NCT02755844,NCT04792749,NCT01205672,NCT01911247,NCT02990728
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
BLM,OR51E2,CYP19A1,FABP4,AKR1B10,FABP5,L3MBTL1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ACHE,HRH3,CYP1A1,HRH2,THPO,ALOX15,ESR2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
ACHE,NR1I2,BLM,XDH,TTR,THPO,AKR1B10
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
BLM,HRH3,OR51E2,CYP19A1,CYP3A4,FABP5,DPP4
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
NFKB1,F3,CYP3A4,XDH,CSNK2A1,MKNK2
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
NFKB1,DPP4,HRH4
AKR1B10,FABP5 NCT02644954 |
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
ACHE,HRH1,ESR2,MAOB,HRH3
NCT01439555 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
MAOB
NCT00000620,NCT00223717,NCT01352026,NCT03617458,NCT00345150 |
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
FABP4
NCT01084486,NCT04972396,NCT02457286,NCT00699036,NCT02696941 |
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT05470998,NCT00056433,NCT01142219,NCT02447874,NCT00513617,NCT02981329
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
OR51E2,TTR,FABP5,ALOX15
NCT01796028,NCT01996696 |
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
CDC25B,BLM,PTPN1,HRH2,AKR1B10,DPP4
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
BLM,HRH3,CYP1A1,XDH,AKR1B10,ALOX15
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NFKB1,DPP4
NCT03258723,NCT00432276,NCT01192152,NCT03179254,NCT04209075,NCT02844803,NCT00108615,NCT00286442,NCT01915550,NCT00316082,NCT01370707,NCT00762957,NCT03670043,NCT03030300,NCT00684528,NCT02088034,NCT00770445,NCT04416269,NCT00820573,NCT01766778,NCT04050098,NCT00046462,NCT00038727,NCT00754403,NCT01890122,NCT05262257,NCT02042664,NCT01814748,NCT00969566,NCT02249910,NCT01334125,NCT00770835,NCT02484209,NCT01107717,NCT01046422,NCT03039075,NCT05440591,NCT01874080,NCT00959101,NCT04998032,NCT00313313,NCT02719756,NCT00683735,NCT00727857,NCT04581447,NCT01192139,NCT03824002,NCT02956044,NCT00772174,NCT00327015,NCT01613755,NCT01464437,NCT00279240 |
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
XDH
NCT02895750,NCT05373680,NCT02848508,NCT00047983 |
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
PTPRC
NCT02815397,NCT02531308,NCT03200015,NCT03600363 |
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
HRH1,HRH3
NCT04865835,NCT00401973,NCT04054973 |
Primary neoplasms of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
NCT02149459,NCT01188096,NCT02040376,NCT01528046,NCT03068832
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NCT01783431,NCT02143050,NCT01638676,NCT03311308,NCT02190838
|
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT01210911,NCT03956056,NCT03889795,NCT01167738,NCT01488552
|
Squamous cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B60-2D01 |
NCT02083692,NCT02394652,NCT03076281,NCT03618654,NCT03833466
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT01808690,NCT04177303,NCT01881828,NCT01483560,NCT02045290
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT02308228,NCT03713801,NCT04264897,NCT03861767,NCT03072485
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT03017833,NCT01566799,NCT04428086,NCT01920191,NCT01324115
|
Neuroendocrine carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C34 |
NCT02823691,NCT00037869,NCT02294006,NCT02279758,NCT02254512
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
HSD17B1,BLM,OR51E2,XDH,AKR1B10
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
HSD17B1,BLM,CYP3A4,TTR,CYP1A2
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
DPP4,GABRA6,CYP1B1,XDH,HRH1
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP1A1,CYP1A2,HRH2,CYP3A4,TTR
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
OR51E2,CYP1B1,HRH2,THPO,DPP4
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
HRH1,HRH4
NCT00280683,NCT02882217 |
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
MAOB
NCT05236530,NCT00616304,NCT00147368 |
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
MAOB,HRH3,ACHE
NCT04220021 |
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NFKB1,MAOB
NCT02018731,NCT01995032 |
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
MKNK2
NCT02614339,NCT01632020,NCT01816659 |
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT02819869,NCT05281926,NCT02672488,NCT01287585
|
Autosomal dominant polycystic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB81 |
NCT04939935,NCT03764605,NCT02903511,NCT02656017
|
Fragile X chromosomeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD55 |
NCT04141163,NCT03722290,NCT03862950,NCT03479476
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
NCT02278965,NCT04616248,NCT03606967,NCT01885013
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
CDC25B,BLM,CYP19A1,ALOX15
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ACHE,NFKB1,CYP19A1,DPP4
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
ACHE,HSD17B1,LMNA,DPP4
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ACHE,CDC25B,BLM,ALOX15
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA,CYP19A1,XDH,F3
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
NCT03086005,NCT02562664,NCT03905941,NCT02026869,NCT04867252,NCT02689843,NCT04973891,NCT02086526,NCT01482286,NCT03981861,NCT03117517,NCT00948402,NCT03674385,NCT00714233,NCT00159536,NCT04113889,NCT02244567,NCT02022007,NCT01622257,NCT03108963,NCT01733459,NCT05394142,NCT03229057,NCT00466622,NCT01581814,NCT00151411,NCT03259919,NCT04852510,NCT03008551,NCT02498522,NCT01775176,NCT00283816,NCT00344851
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CYP19A1,ESR2,PTPN1,MKNK2
NCT01589367,NCT02488564,NCT01042379,NCT00909506,NCT01627067,NCT03192293,NCT02360059,NCT04248998,NCT02427581,NCT05053841,NCT01302002,NCT01310231,NCT00986609,NCT02028221,NCT03006172,NCT02506790,NCT02472353,NCT00930579,NCT03238495,NCT01980823,NCT04899349,NCT04300790,NCT01650506,NCT04143282,NCT02506777,NCT01477060,NCT01266486,NCT04559308 |
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
CDC25B
NCT02285855,NCT02115464 |
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
MKNK2,CSNK2A1
NCT03184493 |
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
MKNK2,PTPRC
NCT00917826 |
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
HRH4,NFKB1,CYP3A4
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ACHE
NCT01796678,NCT03446456 |
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
PTPRC,NFKB1
NCT01842139 |
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
XDH
NCT05093959,NCT02810132 |
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
MAOB,ACHE,HRH1
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
HRH1
NCT04249336,NCT01292070 |
AdenocarcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D40 |
NCT02186847,NCT01877564,NCT01578551
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT02473094,NCT03053544,NCT02437656
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
NCT02848950,NCT03681197,NCT03135301
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
NCT00974714,NCT00157521,NCT00571766
|
Malignant neoplasm metastasis in male genital organsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E06 |
NCT04926155,NCT04925063,NCT01677897
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
NCT03679780,NCT00408577,NCT01037660
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT01529593,NCT01087983,NCT01442870
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
FABP4
NCT02949700,NCT04414540 |
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT02360618,NCT03359239,NCT03379909
|
Malignant neoplasms of prostate, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.Z |
NCT02640534,NCT01561482,NCT02614859
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04631536,NCT04510194,NCT04604678
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NR1I2,TTR,PTPRC
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
HSD17B1,XDH,AKR1B10
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ACHE,CYP1A1,F3
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
BLM,HRH3,THPO
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
AKR1B10,HRH1,BLM
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NFKB1,PTPN1,DPP4
NCT00901979,NCT00353691,NCT00544518,NCT00728351,NCT00333151,NCT00528372,NCT00754689,NCT00174642,NCT01111955,NCT01154348,NCT00081328,NCT00700817,NCT00676338,NCT01117584,NCT01068717,NCT01095653,NCT01135433,NCT00097500,NCT00295633,NCT00643851,NCT02440061,NCT01068730,NCT01068743,NCT00875394,NCT00359112,NCT00427154,NCT01302145,NCT00783744,NCT00605475,NCT00102466,NCT00032487,NCT00316758,NCT00968812,NCT01217892,NCT00332488,NCT00399711,NCT02744820,NCT00798161,NCT00960076,NCT00086502,NCT00541775,NCT00971659,NCT00266253,NCT00698789,NCT01396564,NCT00103857,NCT00479466,NCT00087516,NCT01106625,NCT00525330,NCT01076075,NCT00383578,NCT01204294,NCT00859898,NCT00469586,NCT00838903,NCT01332071,NCT00099866,NCT00374907,NCT01023581,NCT00744367,NCT01340768,NCT00734474,NCT00715624,NCT01204775,NCT01064687,NCT00900146,NCT00918138,NCT01368081,NCT01093794,NCT00871936,NCT00754988,NCT01318109,NCT00856284,NCT00789191,NCT00379769,NCT01434186,NCT00376038,NCT00348712,NCT01357876,NCT00184574,NCT00571519,NCT00499707,NCT00839527,NCT00067951,NCT01059825,NCT00611884,NCT00976937,NCT00975286,NCT00251953,NCT00614055,NCT00420511,NCT00449605,NCT00414245,NCT00767000,NCT01305551,NCT01137812,NCT00701090,NCT01240759,NCT00971243,NCT00885378,NCT00792935,NCT00860288,NCT01381900,NCT00627445,NCT00763451,NCT00855166,NCT01126580,NCT00868790,NCT01034111,NCT00382096,NCT01089192,NCT00698230,NCT00851903,NCT00121641,NCT00915772,NCT01383356,NCT00350779,NCT00131664,NCT00961909,NCT00763815,NCT01089205,NCT00881530,NCT00713830,NCT01296412,NCT00318461,NCT00690456,NCT00121667,NCT01340664,NCT01462266,NCT00712673,NCT00482729,NCT00614120,NCT00111631,NCT00598793,NCT00468039,NCT00279045,NCT00328172,NCT00755287,NCT00263965,NCT01365091,NCT00110851,NCT01353391,NCT00097279,NCT00331851,NCT01245166,NCT00924573,NCT01106677,NCT01292993,NCT01289119,NCT01175473,NCT00263276,NCT00672386,NCT00707031,NCT01472367,NCT00961857,NCT00722371,NCT01318135,NCT00631488,NCT00885352,NCT00069836,NCT00789035,NCT01095666,NCT00543361,NCT01217073,NCT00961480,NCT00830076,NCT00743002,NCT00528879,NCT00960661,NCT00899470,NCT00481663,NCT00519480,NCT00425009,NCT01028391,NCT01106690,NCT00661362,NCT01076088,NCT00454233,NCT00106340,NCT00261352,NCT01071850,NCT01075282,NCT00337610,NCT00375388,NCT05210504,NCT01051011,NCT00086515,NCT01089179,NCT01169779,NCT00673465,NCT01089166,NCT01002807,NCT00613951,NCT00396357,NCT00272064,NCT00000620,NCT00575588,NCT01459809,NCT01211197,NCT00856986,NCT00814372,NCT00975052 |
Sleep-wake disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7B2Z |
HRH1,HRH3
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
HRH3,CYP19A1
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
CES1,ESR2
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
HRH1,MAOB
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
DPP4,PTPN1
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
HRH1
NCT02519543 |
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
THPO,DPP4
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE,HRH3
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE,HRH2
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
CYP3A4,HRH1
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
ESR2,CYP19A1
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
HRH1,HRH3
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
CES1,DPP4
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
HRH3,ACHE
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
ESR2
NCT01263041 |
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
MAOB,HRH1
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ACHE
NCT05426044 |
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
ESR2,NFKB1
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1
NCT04364750 |
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
DPP4,PTPRC
|
Acute viral hepatitisDisease Category: NADisease ICD-11 Code: NA |
NCT03000218,NCT00063232
|
Sex development malformative disorderDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2A |
NCT03862950,NCT03479476
|
Endometrial glandular hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA16.0 |
NCT01685762,NCT04607252
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
NCT03600363,NCT03121677
|
Insulin-resistance syndromesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A44 |
NCT04264897,NCT04148183
|
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT02516085,NCT01388764
|
Small cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.1 |
NCT01266018,NCT03994744
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT00000620,NCT00134433
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT00005107,NCT00344916
|
Other specified non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92.Y |
NCT00063635,NCT00303537
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT02659306,NCT02064374
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT05132439,NCT01380678
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT03047837,NCT01440127
|
Symptoms and signs involving cognition, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.Z |
NCT04098666,NCT00620191
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT03088345,NCT02618824
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
NCT02325401,NCT02402348
|
Chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
NCT03054519,NCT03861416
|
Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
NCT03479476,NCT03862950
|
Other specified malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NCT01926769,NCT01725490
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
NCT00058123,NCT00052715
|
Disorders of intellectual development, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A00.Z |
NCT03862950,NCT03479476
|
Carcinomas of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.0 |
NCT02437812,NCT03162562
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
NCT03378297,NCT02312661
|
Aneurysm/dissectionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD50 |
NCT04224051,NCT04500756
|
Malignant neoplasm metastasis, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E2Z |
NCT01840007,NCT00037869
|
Dental cariesDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA08.0 |
NCT02388178,NCT04750902
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
HRH2,HRH4
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
CDC25B,CYP1A1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
ACHE,NR1I2,BLM,CSNK2A2,MAOB,PTPN1,OR51E2,THPO,ESR2,LMNA,CSNK2A1,F3,GFER,HRH1,PSMB5,FABP4,FABP5
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
ACHE,NR1I2,CDC25B,CES1,BLM,LMNA,PTPN1,OR51E2,CYP1B1,HRH2,XDH,TTR,AKR1B10,ALOX15,MAOB,PTPRC,DPP4
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
ESR2,MAOB
NCT00881725,NCT01733836,NCT01607879,NCT02946996,NCT01215032,NCT02945813,NCT03137186,NCT03465345,NCT04536805,NCT00268476,NCT01243385,NCT01864096,NCT01620593,NCT02497638 |
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
HRH1,PTPN1
NCT02063802,NCT01677923,NCT03349775,NCT01725126,NCT00892073,NCT00842400,NCT03000218,NCT00941382,NCT04839237,NCT00349635,NCT00120146,NCT00631033 |
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4,PTPN1
NCT00362323,NCT02629627,NCT01234649,NCT00703755,NCT04817787,NCT01046500,NCT02778776,NCT02773927,NCT00349128,NCT00348725 |
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
ACHE,PSMB5,NFKB1,CYP1B1,CYP3A4,HRH2,AKR1B10,FABP5,ALOX15,PTPRC,DPP4
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
NR1I2,ALOX15,XDH,AKR1B10,PTPRC,CSNK2A1,CYP1A2,PSMB5,CSNK2A3,FABP5
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
BLM,LMNA,F3,CSNK2A3,OR51E2,CSNK2A1,FABP5,L3MBTL1,HRH1,ESR2
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ACHE,CYP19A1,XDH,AKR1B10,FABP5,HRH1,OR51E2,HRH2,FABP5,PTPRC
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CDC25B,LMNA,HRH1,OR51E2,XDH,AKR1B10,ALOX15,CSNK2A2,PTPRC,DPP4
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
BLM,OR51E2,CYP19A1,FABP4,AKR1B10,FABP5,L3MBTL1,CDC25B,AKR1B10,CYP19A1
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
LMNA,BLM,CSNK2A3,HRH1,CYP1B1,CYP19A1,AKR1B10,FABP5,PTPRC,DPP4
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
Primary psychotic disorder manifestationDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A25 |
MAOB
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
MAOB
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
Ophthalmic devices/implants/grafts injuryDisease Category: 23.External causes of morbidity or mortalityDisease ICD-11 Code: PK97 |
PTPN1
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
ESR2
|
Transplanted organ/tissueDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QB63 |
PTPRC
|
NasopharyngitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA00 |
HRH1
|
Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F3
|
EncephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E47 |
XDH
|
Episodic vestibular syndromeDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB31 |
HRH1
|
Skin tag/polypDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK71 |
MAOB
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
XDH
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Inborn purine/pyrimidine/nucleotide metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C55 |
XDH
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
PruritusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EC90 |
HRH1
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
HRH3
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
XDH
|
Breathing abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11 |
HRH1
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
F3
|
Gastro-oesophageal reflux diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA22 |
HRH2
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
F3
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR2
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
CDC25B
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
PTPRC
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
CYP19A1
|
Peptic ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA61 |
HRH2
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
HRH1
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
NFKB1
|
AmyloidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5D00 |
TTR
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
PTPN1
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
MAOB
|
Morning sickness disorderDisease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SC00 |
HRH1
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
PTPRC
|
Synthesis disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52-5C59 |
CES1
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
CardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43 |
TTR
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
MAOB
|
Respiratory system diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB40-CB7Z |
HRH1
|
Conjunctiva disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A60 |
HRH1
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
SomnolenceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG42 |
HRH3
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
ESR2
|
Skin cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30-2C37 |
MAOB
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
Peroxisomal diseaseDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C57 |
CES1
|
NarcolepsyDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A20 |
HRH3
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
THPO
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
HRH1
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
HRH1
|
Mineral deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5K |
XDH
|
Tension-type headacheDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A81 |
HRH1
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
Osteoarthritis of kneeDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
NCT01112722
|
Squamous cell carcinoma of oropharynxDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6A.0 |
NCT03618654
|
Impaired glucose toleranceDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.1 |
NCT01234649
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT03651895
|
Nephritic syndromeDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB40 |
NCT02662283
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
NCT05025488
|
Acute ischaemic heart disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA4Z |
NCT05305898
|
Low back painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84.2 |
NCT04055012
|
PterygiumDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A61.1 |
NCT01380678
|
Argininosuccinic aciduriaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.A0 |
NCT00345605
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT01485315
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
NCT01710527
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT02931253
|
LeprosyDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B20 |
NCT05243654
|
Migraine disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SD10 |
NCT02593097
|
HypercholesterolaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.0 |
NCT00000620
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
NCT05468554
|
Beta thalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50.2 |
NCT00006136
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
NCT04275713
|
Unspecified adverse cutaneous reactions to medicationDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EH7Z |
NCT03376620
|
Generalised anxiety disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B00 |
NCT00809536
|
MelasmaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60.1 |
NCT01603446
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT00405665
|
Precursor cell lymphoblastic leukaemia, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH5J37 |
NCT01324180
|
Cardiac arrestDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC82 |
NCT03640949
|
Chronic lymphocytic leukaemia or small lymphocytic lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82.0 |
NCT01750567
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
NCT02587741
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
NCT02967276
|
Osteosarcoma of bone and articular cartilage of other specified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51.Y |
NCT01981525
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
NCT05215990
|
Columnar metaplastic epithelium of the oesophagus, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA23.Z |
NCT01465113
|
Adenocarcinoma, endocervical typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH0GS9 |
NCT02394652
|
Large cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.3 |
NCT02186847
|
Polyneuropathy, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
NCT04780854
|
AngiosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B56 |
NCT01042379
|
Obstructive sleep apnoeaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A41 |
NCT04530747
|
Alcoholic hepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB94.1 |
NCT00200746
|
Malignant lymphoma, not elsewhere classifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33.5 |
NCT00719472
|
Lipoatrophy/lipodystrophyDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EF01 |
NCT00362440
|
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04510194
|
BlindnessDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9D90.6 |
NCT03490019
|
Tuberculosis of the respiratory systemDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10 |
NCT00677339
|
Melanoma of skin, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30.Z |
NCT02129075
|
Pleural mesotheliomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26 |
NCT04345705
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
NCT04750135
|
Hidradenitis suppurativaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED92 |
NCT04649502
|
Galactose-1-phosphate uridyltransferase deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C51.40 |
NCT03580122
|
Huntington diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01.10 |
NCT04826692
|
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT04088448
|
Spastic cerebral palsyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D20 |
NCT03710343
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
NCT00401973
|
MyelofibrosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A22 |
NCT05025488
|
Acute myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41 |
NCT02929888
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00344734
|
Primary progressive multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40.1 |
NCT05349474
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
NCT00361868
|
Central diabetes insipidusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A61.5 |
NCT02460354
|
Malignant neoplasms of ill-defined sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
NCT03477162
|
Cutaneous T-cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1951 |
NCT02061449
|
Glioma, malignantDisease Category: X.Extension CodesDisease ICD-11 Code: XH4RQ3 |
NCT05457959
|
Schizophrenia or other primary psychotic disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A2Z |
NCT04511416
|
Burn and burn infectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND90-NE2Z |
NCT04530058
|
Neuropathic painDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43.0 |
NCT00971295
|
Secondary progressive multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40.2 |
NCT05349474
|
Inflammatory carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C62 |
NCT00986609
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT04767841
|
Other specified disorders of carbohydrate absorption or transportDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C61.Y |
NCT02291458
|
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
NCT00000620
|
HypopituitarismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A61.0 |
NCT03490019
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
NCT00137124
|
Pregnancy/childbirth/puerperium maternal infectionDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JB63 |
NCT03056274
|
Urogenital cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C95-2C9Z |
NCT02365597
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT02684578
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
CYP1A1
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
NR1I2
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
CYP1A1
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
FABP4
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
F3
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
DPP4
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
FABP4
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CYP1A1
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
FABP4
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
ACHE
|
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
FABP4
|