Plant ID: NPO6349
Plant Latin Name: Celastrus Orbiculatus
Taxonomy Genus: Celastrus
Taxonomy Family: Celastraceae
NCBI TaxonomyDB:
85181
Plant-of-the-World-Online:
n.a.
Antiphlogistic; Antirheumatic; Cancer; Depurative; Tonic
South Korea; China
Ingredient ID: NPC91406
Ingredient ID: NPC90614
Ingredient ID: NPC88593
Ingredient ID: NPC83538
Ingredient ID: NPC82730
Ingredient ID: NPC76851
Ingredient ID: NPC66761
Ingredient ID: NPC5616
Ingredient ID: NPC481056
Ingredient ID: NPC481055
Ingredient ID: NPC481054
Ingredient ID: NPC481053
Ingredient ID: NPC476094
Ingredient ID: NPC476035
Ingredient ID: NPC475652
Ingredient ID: NPC475429
Ingredient ID: NPC475122
Ingredient ID: NPC475039
Ingredient ID: NPC474656
Ingredient ID: NPC473889
Ingredient ID: NPC473871
Ingredient ID: NPC473870
Ingredient ID: NPC473869
Ingredient ID: NPC473860
Ingredient ID: NPC473758
Ingredient ID: NPC473613
Ingredient ID: NPC4341
Ingredient ID: NPC4170
Ingredient ID: NPC302777
Ingredient ID: NPC301556
Ingredient ID: NPC289407
Ingredient ID: NPC283375
Ingredient ID: NPC278552
Ingredient ID: NPC275592
Ingredient ID: NPC270498
Ingredient ID: NPC248970
Ingredient ID: NPC246943
Ingredient ID: NPC246841
Ingredient ID: NPC243302
Ingredient ID: NPC21100
Ingredient ID: NPC210591
Ingredient ID: NPC208472
Ingredient ID: NPC200592
Ingredient ID: NPC197686
Ingredient ID: NPC195647
Ingredient ID: NPC195017
Ingredient ID: NPC183122
Ingredient ID: NPC17877
Ingredient ID: NPC167571
Ingredient ID: NPC163087
Ingredient ID: NPC159520
Ingredient ID: NPC14499
Ingredient ID: NPC1408
Ingredient ID: NPC138180
Ingredient ID: NPC137619
Ingredient ID: NPC136165
Ingredient ID: NPC126029
Ingredient ID: NPC122318
Ingredient ID: NPC121290
Ingredient ID: NPC112454
Ingredient ID: NPC108831
Ingredient ID: NPC100913
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Drug Transporter | ATP-binding cassette | ABCB1 | P-glycoprotein 1 | P08183 | CHEMBL4302 |
Therapeutic Target | Enzyme | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | P05186 | CHEMBL5979 |
Therapeutic Target | Nuclear hormone receptor subfamily 1 | THRB | Thyroid hormone receptor beta-1 | P10828 | CHEMBL1947 |
Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
Therapeutic Target | Transferase | TERT | Telomerase reverse transcriptase | O14746 | CHEMBL2916 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 184 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT03636932 | RENACTIF: Reduction of the Thrombotic Phenotype in Renal Insufficiency With N-AcetylCysteine | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03596125 | Correction of Neonatal Glutathione by N-acetylcysteine in Pregnant Women at Risk of Premature Birth (GSH MAP) | premature birth | Acetylcysteine (NPC248970) | NP level |
NCT02212678 | Repeated-Dose Oral N-acetylcysteine for the Treatment of Parkinson's Disease | Parkinson disease | Acetylcysteine (NPC248970) | NP level |
NCT03238300 | Neuroscience-Informed Treatment Development for Adolescent Alcohol Use | alcohol drinking | Acetylcysteine (NPC248970) | NP level |
NCT00552786 | Antioxidation Medication for Noise-induced Hearing Loss | hearing loss | Acetylcysteine (NPC248970) | NP level |
NCT04918719 | Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke | Ischemic stroke | Acetylcysteine (NPC248970) | NP level |
NCT04964843 | A Study of NAC for AUD | alcohol dependence | Acetylcysteine (NPC248970) | NP level |
NCT04792021 | Effect of N-acetylcysteine on Oxidative Stress in COVID-19 Patients | COVID-19 | Acetylcysteine (NPC248970) | NP level |
NCT01082445 | Effects of N-acetylcysteine on Diabetic Foot Oxygenation | diabetic foot | Acetylcysteine (NPC248970) | NP level |
NCT03730064 | Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression | depressive disorder;bipolar disorder | Acetylcysteine (NPC248970) | NP level |
NCT03680911 | NAC for Head Trauma-induced Anosmia | injury | Acetylcysteine (NPC248970) | NP level |
NCT03120468 | Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder | alcohol dependence | Acetylcysteine (NPC248970) | NP level |
NCT00830193 | N-Acetylcysteine in Critically Ill Patients Undergoing Contrast Enhanced Computed Tomography | kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT05123365 | An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms | essential thrombocythemia;myelofibrosis;polycythemia vera | Acetylcysteine (NPC248970) | NP level |
NCT01470027 | N-Acetylcysteine for Neuroprotection in Parkinson's Disease | Parkinson disease | Acetylcysteine (NPC248970) | NP level |
NCT02362425 | Antioxidant Therapy in RYR1-Related Congenital Myopathy | neuromuscular disease | Acetylcysteine (NPC248970) | NP level |
NCT04370288 | Clinical Application of Methylene Blue for Treatment of Covid-19 Patients | COVID-19 | Acetylcysteine (NPC248970) | NP level |
NCT01741207 | Effect of N-acetylcystein in Myocardial Infarction | acute myocardial infarction | Acetylcysteine (NPC248970) | NP level |
NCT04703036 | Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19 | COVID-19 | Acetylcysteine (NPC248970) | NP level |
NCT00273702 | An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling | gambling behaviour | Acetylcysteine (NPC248970) | NP level |
NCT01322009 | Overcoming Membrane Transporters to Improve CNS Drug Delivery - Improving Brain Antioxidants After Traumatic Brain Injury | brain injury | Acetylcysteine (NPC248970) | NP level |
NCT04740580 | Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease | Alzheimer disease | Acetylcysteine (NPC248970) | NP level |
NCT00463749 | Myocardial Salvage and Contrast Dye Induced Nephropathy Reduction by N-Acetylcystein | myocardial infarction | Acetylcysteine (NPC248970) | NP level |
NCT00996424 | The Effect of Inhaled N-Acetylcysteine Compared to Normal Saline on Sputum Rheology and Lung Function | cystic fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT01439828 | Clinical Trial of N-acetylcysteine Versus Placebo Efficacy in the Cannabis Withdrawal | cannabis dependence | Acetylcysteine (NPC248970) | NP level |
NCT02737358 | N-acetylcysteine for Tobacco Use Disorder | nicotine dependence | Acetylcysteine (NPC248970) | NP level |
NCT01384591 | Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly | aging | Acetylcysteine (NPC248970) | NP level |
NCT02723162 | Translational Neuropsychopharmacology Research of Nicotine Addiction | nicotine dependence | Acetylcysteine (NPC248970) | NP level |
NCT01808521 | A Pilot Study of N-acetylcysteine in Thrombotic Thrombocytopenia Purpura | thrombotic thrombocytopenic purpura;autoimmune thrombocytopenic purpura | Acetylcysteine (NPC248970) | NP level |
NCT00627705 | A Study of N-Acetyl Cysteine in Children With Autism | autism | Acetylcysteine (NPC248970) | NP level |
NCT02379637 | Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and Cough | common cold | Acetylcysteine (NPC248970) | NP level |
NCT02182167 | A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis | drug-induced hepatitis | Acetylcysteine (NPC248970) | NP level |
NCT02294591 | NACOS - The Effect of N-acetylcystein for Depressive Symptoms in Patients Suffering From Bipolar Depression | bipolar disorder | Acetylcysteine (NPC248970) | NP level |
NCT01849016 | N-Acetylcysteine in Patients With Sickle Cell Disease | sickle cell anemia | Acetylcysteine (NPC248970) | NP level |
NCT03154580 | Marijuana Cue-Reactivity & Seeking Behavior in Regular Cannabis Users | cannabis dependence | Acetylcysteine (NPC248970) | NP level |
NCT04756622 | N-acetyl Cysteine for the Prevention of Oral Mucositis After Autologous Hematopoietic Cell Transplantation. | mucositis | Acetylcysteine (NPC248970) | NP level |
NCT01856868 | Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study) | Becker muscular dystrophy | (-)-Epicatechin (NPC126029) | NP level |
NCT03104725 | Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease? | Parkinson disease | Acetylcysteine (NPC248970) | NP level |
NCT00998972 | N-acetyl-cysteine (NAC) and Kidney Graft Function | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03862586 | NAC Effect on Hox Genes Expressions in RIF | female infertility | Acetylcysteine (NPC248970) | NP level |
NCT01251029 | Effect of N-acetylcysteine on Renal Functioning of Chronic Kidney Diseases(CKD) Patients After General Anesthesia | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03216954 | Influence of n-Acetylcysteine Maintenance on Alcohol Effects | alcohol dependence | Acetylcysteine (NPC248970) | NP level |
NCT03702738 | Adjunctive NAC in Adult Patients With Pulmonary Tuberculosis | tuberculosis | Acetylcysteine (NPC248970) | NP level |
NCT04123405 | Efficacy and Safety of Acetylcysteine for the Treatment of Acute Uncomplicated Rhinosinusitis | sinusitis | Acetylcysteine (NPC248970) | NP level |
NCT03499249 | N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy | biliary atresia | Acetylcysteine (NPC248970) | NP level |
NCT01555970 | Efficacy Study of add-on Therapy With N-Acetylcysteine in Resistant Obsessive-compulsive Disorder | obsessive-compulsive disorder | Acetylcysteine (NPC248970) | NP level |
NCT01172275 | N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder | obsessive-compulsive disorder | Acetylcysteine (NPC248970) | NP level |
NCT03720483 | Inhaled NAC in Treatment of IPF | idiopathic pulmonary fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT02994875 | Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine Dependence | cocaine dependence | Acetylcysteine (NPC248970) | NP level |
NCT02750319 | Amiodarone and N-Acetylcysteine or Amiodarone Alone for Preventing Atrial Fibrillation After Thoracic Surgery | atrial fibrillation | Acetylcysteine (NPC248970) | NP level |
NCT01118663 | Safety and Efficacy Study of a New Formulation of Acetylcysteine Injection | drug-induced liver injury | Acetylcysteine (NPC248970) | NP level |
NCT02583672 | Role of Oxidative Stress and Inflammation in Type 1 Gaucher Disease (GD1) | Gaucher disease type 1 | Acetylcysteine (NPC248970) | NP level |
NCT02707640 | A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF) | idiopathic pulmonary fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT03460808 | The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia | autoimmune thrombocytopenic purpura | Acetylcysteine (NPC248970) | NP level |
NCT01232257 | Effect of N-acetylcysteine (NAC) on Hydrogen Sulfide (H2S) in Chronic Kidney Disease (CKD) | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT01354132 | N-Acetyl-Cysteine (NAC) in Early Phase Schizophrenia Spectrum Psychosis | mental or behavioural disorder | Acetylcysteine (NPC248970) | NP level |
NCT00428883 | High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic Sclerosis | diffuse scleroderma | Acetylcysteine (NPC248970) | NP level |
NCT04368598 | The Combination of High-dose Dexamethasone and Acetylcysteine as the Treatment of Newly-diagnosed ITP | autoimmune thrombocytopenic purpura | Acetylcysteine (NPC248970) | NP level |
NCT05485558 | the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy | epilepsy | Acetylcysteine (NPC248970) | NP level |
NCT04945096 | Outcomes of Patients After Allo-HSCT With Decitabine and NAC | graft versus host disease | Acetylcysteine (NPC248970) | NP level |
NCT03008889 | A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder | autism spectrum disorder | Acetylcysteine (NPC248970) | NP level |
NCT03149107 | "Multimodal Prevention of Psychosis - Investigating Efficacy of N-Acetylcysteine and Psychotherapy in CHR-Patients" | schizophrenia | Acetylcysteine (NPC248970) | NP level |
NCT03843541 | A Clinical Trial to Compare the Efficacy and Safety of 1-week Treatment of Intravenous N-acetylcysteine (NAC) 600 mg Twice Daily, Ambroxol Hydrochloride 30 mg Twice Daily and Placebo as Expectorant Therapies in Adult Chinese Patients With Respiratory Tract Diseases and Abnormal Mucus Secretions | respiratory system disease | Acetylcysteine (NPC248970) | NP level |
NCT01664260 | Efficacy Mechanism of N-acetylcysteine in Patients With Posttraumatic Stress Disorder | post-traumatic stress disorder | Acetylcysteine (NPC248970) | NP level |
NCT01131468 | Prevention of Drug Induced Ototoxicity in Peritoneal Dialysis Patients by N-Acetylcysteine | hearing loss | Acetylcysteine (NPC248970) | NP level |
NCT04987775 | GWICTIC: NAC Mechanistic Study in Gulf War Veterans | persian gulf syndrome | Acetylcysteine (NPC248970) | NP level |
NCT01187108 | Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru | altitude sickness | Acetylcysteine (NPC248970) | NP level |
NCT03956888 | The Anti-oxidant Effects of N-Acetylcysteine in Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Acetylcysteine (NPC248970) | NP level |
NCT01840345 | The Role of N-acetyl-l-cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients With Chronic Neuropathic Pain | neuropathic pain | Acetylcysteine (NPC248970) | NP level |
NCT04440280 | Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy | Fuchs endothelial corneal dystrophy | Acetylcysteine (NPC248970) | NP level |
NCT04928495 | Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 | COVID-19 | Acetylcysteine (NPC248970) | NP level |
NCT01675661 | Achieving Cannabis Cessation-Evaluating N-Acetylcysteine Treatment | cannabis dependence | Acetylcysteine (NPC248970) | NP level |
NCT02493933 | Phytoestrogen, NO Donors, N-acetyl Cysteine Add Therapy to Clomiphene Citrate to Improve Pregnancy Rate in PCO Patients | infertility | Acetylcysteine (NPC248970) | NP level |
NCT00506506 | Effect of N-Acetylcysteine (NAC) on Creatinine in Chronic Kidney Disease | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT01172288 | N-acetylcysteine (NAC) for Children With Tourette Syndrome | Tourette syndrome | Acetylcysteine (NPC248970) | NP level |
NCT00639496 | Study of the Effects of High-dose N-acetylcysteine (NAC) in Idiopathic Pulmonary Fibrosis (IPF) | pulmonary fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT04712435 | Efficacy of N-acetylcysteine Versus Placebo as Prophylaxis of Sinusoidal Obstruction Syndrome in Patients Undergoing Hematopoietic Stem Cell Transplantation | hepatic veno-occlusive disease | Acetylcysteine (NPC248970) | NP level |
NCT01797575 | N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder | bipolar disorder | Acetylcysteine (NPC248970) | NP level |
NCT01753752 | Evaluation of the Corneal Residence Time of Chitosan-N-acetylcysteine Eye Drops in Patients With Dry Eye Syndrome After Single and Multiple Instillation | dry eye syndrome | Acetylcysteine (NPC248970) | NP level |
NCT02259595 | Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC | noise-induced hearing loss | Acetylcysteine (NPC248970) | NP level |
NCT04481048 | Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 | neurofibromatosis type 1 | Acetylcysteine (NPC248970) | NP level |
NCT00483314 | Homocystinuria: Treatment With N-Acetylcysteine | homocystinuria | Acetylcysteine (NPC248970) | NP level |
NCT01885338 | N-acetylcysteine (NAC) for Improving Cognitive Dysfunction in Schizophrenia | schizophrenia | Acetylcysteine (NPC248970) | NP level |
NCT05122559 | Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis | chronic progressive multiple sclerosis | Acetylcysteine (NPC248970) | NP level |
NCT00650091 | Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in Patients With IPF | pulmonary fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT04545008 | Trial of Famotidine & N-Acetyl Cysteine for Outpatients With COVID-19 | COVID-19 | Acetylcysteine (NPC248970) | NP level |
NCT03236662 | (-)- Epicatechin Becker Muscular Dystrophy | Becker muscular dystrophy | (-)-Epicatechin (NPC126029) | NP level |
NCT00453180 | A Study of Oral N-Acetylcysteine in Children With Autism Spectrum Disorders | Asperger syndrome;autism | Acetylcysteine (NPC248970) | NP level |
NCT04481035 | Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1 | neurofibromatosis type 1 | Acetylcysteine (NPC248970) | NP level |
NCT02505087 | Pharmacological Treatment of a Rare Genetic Disease: N-acetylcysteine in Myopathy Associated Selenoprotein N-related Myopathy (SEPN1-RM) | myopathy | Acetylcysteine (NPC248970) | NP level |
NCT00993265 | N-Acetylcysteine for Pediatric Trichotillomania | Hair-pulling | Acetylcysteine (NPC248970) | NP level |
NCT01214083 | N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol Dependence | alcohol dependence | Acetylcysteine (NPC248970) | NP level |
NCT00374088 | N-Acetylcysteine in Neonatal Congenital Heart Surgery (INACT Study) | transposition of the great arteries | Acetylcysteine (NPC248970) | NP level |
NCT01015209 | Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers | dry eye syndrome | Acetylcysteine (NPC248970) | NP level |
NCT04405193 | The Efficacy of N-acetylcysteine Versus Placebo for the Treatment of Metamphetamine Withdrawal Symptoms | methamphetamine dependence | Acetylcysteine (NPC248970) | NP level |
NCT01800526 | A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease | sickle cell anemia | Acetylcysteine (NPC248970) | NP level |
NCT01704482 | N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve Replacement | kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03063021 | The FIGHT-RP1 Study | retinitis pigmentosa | Acetylcysteine (NPC248970) | NP level |
NCT00004467 | Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen | Acute hepatic failure | Acetylcysteine (NPC248970) | NP level |
NCT00136825 | Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1 | cocaine dependence | Acetylcysteine (NPC248970) | NP level |
NCT04732000 | Oxidative Stress and Surgical Recovery | pain | Acetylcysteine (NPC248970) | NP level |
NCT05070650 | Efficacy and Safety of the Combination of Acetylcysteine, Paracetamol and Phenylephrine for the Treatment of Common Cold | common cold | Acetylcysteine (NPC248970) | NP level |
NCT02141620 | n-Acetylcysteine and Cocaine | cocaine dependence | Acetylcysteine (NPC248970) | NP level |
NCT04312594 | Jaktinib Dihydrochloride Monohydrate in Idiopathic Pulmonary Fibrosis | idiopathic pulmonary fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT03391856 | Prolonged Isolated Thrombocytopenia After Allo-SCT : N-acetyl-L-cysteine (NAC) Versus Supportive Therapy | Thrombocytopenia | Acetylcysteine (NPC248970) | NP level |
NCT00962442 | N-Acetylcysteine in Severe Acute Alcoholic Hepatitis | Hepatitis, Alcoholic | Acetylcysteine (NPC248970) | NP level |
NCT01878669 | Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention | coronary artery disease | Acetylcysteine (NPC248970) | NP level |
NCT00775476 | Treatment of Systemic Lupus Erythematosus (SLE) With N-acetylcysteine | systemic lupus erythematosus | Acetylcysteine (NPC248970) | NP level |
NCT05241262 | Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione Levels | mitochondrial disease | Acetylcysteine (NPC248970) | NP level |
NCT00332605 | N-Acetyl Cysteine Plus Naltrexone in Methamphetamine Dependence | methamphetamine dependence | Acetylcysteine (NPC248970) | NP level |
NCT03164421 | N-Acetylcysteine and L-carnitine in Pcos | polycystic ovary syndrome | Acetylcysteine (NPC248970) | NP level |
NCT04982146 | Intratumoral Bromelain + Acetylcysteine in Relapsed and Unresectable Pseudomyxoma Peritonei | pseudomyxoma peritonei | Acetylcysteine (NPC248970) | NP level |
NCT00751257 | N-Acetylcysteine and Smoking Reduction | nicotine dependence | Acetylcysteine (NPC248970) | NP level |
NCT05081479 | A Study of N-Acetylcysteine (N-AC)in People Receiving CAR T-cell Therapy for Lymphoma | lymphoma | Acetylcysteine (NPC248970) | NP level |
NCT05494398 | Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open Label | autism spectrum disorder | Acetylcysteine (NPC248970) | NP level |
NCT00863785 | Treatment of Severe Alcoholic Hepatitis With Corticoids Plus N Acetyl Cysteine Versus Corticoids Alone | Hepatitis, Alcoholic | Acetylcysteine (NPC248970) | NP level |
NCT03241472 | Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole | infertility | Acetylcysteine (NPC248970) | NP level |
NCT01612221 | Oral N-acetylcysteine for Protection of Human Nevi Against UV-induced Oxidative Stress/Damage in Vivo | melanoma | Acetylcysteine (NPC248970) | NP level |
NCT00391911 | Study of N-Acetylcysteine (NAC) and Continuous Renal Replacement Therapy (CRRT) for the Treatment of Rhabdomyolysis | rhabdomyolysis | Acetylcysteine (NPC248970) | NP level |
NCT00440869 | Effects of N-acetylcysteine on Muscle Fatigue in Hemodialysis | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03252925 | A Safety and Efficacy Study of NAC in Patients With TA-TMA | Abnormality of blood and blood-forming tissues | Acetylcysteine (NPC248970) | NP level |
NCT04864496 | Effects of Treatment With N- Acetylcysteine on Visual Outcomes in Patients With Retinitis Pigmentosa | retinitis pigmentosa | Acetylcysteine (NPC248970) | NP level |
NCT00609102 | Antioxidant Treatment of Type 2 Diabetes | type 2 diabetes mellitus | Acetylcysteine (NPC248970) | NP level |
NCT03423667 | Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients With Cocaine Addiction | cocaine dependence | Acetylcysteine (NPC248970) | NP level |
NCT01063205 | NAC as a Potential Treatment for Methamphetamine Dependence | substance abuse;methamphetamine dependence | Acetylcysteine (NPC248970) | NP level |
NCT04023266 | A Pilot Randomized Controlled Trial of Intravenous N-acetyl Cysteine in STEMI | ST Elevation Myocardial Infarction | Acetylcysteine (NPC248970) | NP level |
NCT01771978 | Ischaemia-réperfusion During the Coronary Surgery With Beating Heart | ischemia reperfusion injury | Acetylcysteine (NPC248970) | NP level |
NCT03346681 | N-Acetyl-cysteine in Early Acute Respiratory Distress Syndrome | acute respiratory distress syndrome | Acetylcysteine (NPC248970) | NP level |
NCT05460858 | NAC Effect on Infertile Women With Endometrioma | female infertility | Acetylcysteine (NPC248970) | NP level |
NCT00611897 | N-acetylcysteine and NMDA Antagonist Interactions | Cognitive impairment | Acetylcysteine (NPC248970) | NP level |
NCT04300920 | Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial | idiopathic pulmonary fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT00497328 | COmbined N-acetylcysteine and Bicarbonate in PCI To Reduce Adverse Side Effect of contrasT | kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03055377 | N-Acetylcysteine for Youth Cannabis Use Disorder | cannabis dependence | Acetylcysteine (NPC248970) | NP level |
NCT03679442 | Macrophage Markers, Soluble CD163 (sCD163) and Soluble CD206 (sCD206) in Paracetamol Overdose | injury | Acetylcysteine (NPC248970) | NP level |
NCT04154982 | N-Acetylcysteine Protection Against Radiation Induced Cellular Damage | cardiac arrhythmia | Acetylcysteine (NPC248970) | NP level |
NCT02080182 | Effect of Acetylcysteine in Pediatric Acute Pyelonephritis. | pyelonephritis | Acetylcysteine (NPC248970) | NP level |
NCT04916080 | N-acetyl Cysteine: the Effectiveness and Safety in a Cohort of Pediatric Patients With Chronic Kidney Disease | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT04381897 | Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome | Cornelia de Lange syndrome | Acetylcysteine (NPC248970) | NP level |
NCT01880866 | (-)-Epicatechin and Pulmonary Arterial Hypertension | pulmonary arterial hypertension | (-)-Epicatechin (NPC126029) | NP level |
NCT01271088 | Protective Effect of N-acetylcysteine Against From Ototoxicity | hearing loss | Acetylcysteine (NPC248970) | NP level |
NCT01033149 | N-acetylcysteine in the Treatment of Bulimia Nervosa | bulimia nervosa | Acetylcysteine (NPC248970) | NP level |
NCT04291066 | Prospective Analysis of the Use of N-Acetylcysteine and Vitamins in the Treatment of TBI in Geriatric Patients | brain injury | Acetylcysteine (NPC248970) | NP level |
NCT04278898 | Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose | autism spectrum disorder | Acetylcysteine (NPC248970) | NP level |
NCT01506765 | Schizophrenia, Related Troubles and Glutathione: Clinical Trial. Effects of Oral Administration of N-Acetylcysteine (NAC) on the Brain Glutathione Level and on the Symptoms of Schizophrenia | schizophrenia | Acetylcysteine (NPC248970) | NP level |
NCT00575419 | Safety Study Of N-Acetylcysteine For Prevention Of Contrast Induced Nephropathy In Patients w/Stage 3 Renal Failure | kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT02088502 | Theophylline, N-acetylcysteine, and Theophylline Plus N-acetylcysteine in Preventing Contrast-induced Nephropathy | kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03707951 | N-Acetylcysteine for Adolescent Alcohol Use Disorder | alcohol dependence | Acetylcysteine (NPC248970) | NP level |
NCT04374461 | A Study of N-acetylcysteine in Patients With COVID-19 Infection | COVID-19 | Acetylcysteine (NPC248970) | NP level |
NCT02775734 | NAC in CC Resistant PCOS After LOD | polycystic ovary syndrome | Acetylcysteine (NPC248970) | NP level |
NCT00676195 | An Open-Label Study of N-Acetyl Cysteine in Children With Autism | autism | Acetylcysteine (NPC248970) | NP level |
NCT03556371 | Evaluation of N-Acetylcysteine Efficacy to Reduce the Craving and to Prolong Abstinence Time of Coca Paste | cocaine dependence | Acetylcysteine (NPC248970) | NP level |
NCT00568087 | N-acetylcysteine in Alcohol Dependence | alcohol dependence | Acetylcysteine (NPC248970) | NP level |
NCT00809094 | NAC Phase IIB: A Multi-Center, Phase IIB, Randomized, Placebo-controlled, Double-Blind Study Of The Effects Of N-Acetylcysteine On Redox Changes and Lung Inflammation In Cystic Fibrosis Patients | cystic fibrosis | Acetylcysteine (NPC248970) | NP level |
NCT01495260 | A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants | adrenomyeloneuropathy | Acetylcysteine (NPC248970) | NP level |
NCT02269540 | A New Treatment Approach for Major Depressive Disorder Based Upon Targeting Monoamine Oxidase A (MAO-A) | major depressive disorder | Acetylcysteine (NPC248970) | NP level |
NCT03121989 | Study to Evaluate the Feasibility of 13-C Pyruvate Imaging in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy | breast cancer | Acetylcysteine (NPC248970) | NP level |
NCT00542750 | An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents | cannabis dependence | Acetylcysteine (NPC248970) | NP level |
NCT03306979 | Memory and Antioxidants in Vascular Impairment Trial | Cognitive impairment | Acetylcysteine (NPC248970) | NP level |
NCT04594733 | The Effect of Minocycline and N-acetylcysteine for the Treatment of Fibromyalgia | fibromyalgia | Acetylcysteine (NPC248970) | NP level |
NCT00354770 | N-Acetyl Cysteine in Trichotillomania | Hair-pulling | Acetylcysteine (NPC248970) | NP level |
NCT01381354 | Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) | multiple sclerosis | Acetylcysteine (NPC248970) | NP level |
NCT02040818 | Treatment of Hemodialysis Catheter-Related Bacteremia | bacteriemia | Acetylcysteine (NPC248970) | NP level |
NCT00780962 | N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients | kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT00205647 | Study of Expectorant Activity of Oral N-acetylcystein (NAC) in Patients With Stable Chronic Bronchitis | chronic bronchitis | Acetylcysteine (NPC248970) | NP level |
NCT00736866 | The Acetylcysteine for Contrast-Induced Nephropathy Trial | acute kidney failure | Acetylcysteine (NPC248970) | NP level |
NCT00003346 | Combination Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma | cutaneous melanoma | Acetylcysteine (NPC248970) | NP level |
NCT04260516 | The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major | beta-thalassemia major | Acetylcysteine (NPC248970) | NP level |
NCT01017796 | Contrast Agent-associated Nephrotoxicity in Intensive Care Unit Patients | kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT03493178 | Glutathione in Mild Cognitive Impairment | Cognitive impairment | Acetylcysteine (NPC248970) | NP level |
NCT01005810 | A Trial of N-Acetylcysteine (an Over-the-Counter Medicine) in Adolescents Who Smoke Marijuana | cannabis dependence | Acetylcysteine (NPC248970) | NP level |
NCT04155632 | Neurocircuit Strategy to Decrease Cocaine Cue Reactivity | cocaine dependence | Acetylcysteine (NPC248970) | NP level |
NCT00655928 | Modulation of Lung Injury Complicating Lung Resection | acute lung injury | Acetylcysteine (NPC248970) | NP level |
NCT04920448 | N-ACETYLCYSTEINE FOR THROMBOLYSIS IN ACUTE STROKE | stroke | Acetylcysteine (NPC248970) | NP level |
NCT00975689 | Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl Cysteine | Niemann-Pick disease type C | Acetylcysteine (NPC248970) | NP level |
NCT01210456 | Efficacy Trial of N-Acetylcysteine and Sodium Bicarbonate for the Prevention of Contrast-Induced Acute Kidney Injury | chronic kidney disease | Acetylcysteine (NPC248970) | NP level |
NCT00218491 | Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1 | cocaine dependence | Acetylcysteine (NPC248970) | NP level |
NCT05340504 | Evaluating the Hypothesized Mechanism of Action of N-acetylcysteine for Bipolar Disorder | bipolar I disorder | Acetylcysteine (NPC248970) | NP level |
NCT00211653 | Acetylcysteine in the Prevention of Renal Failure After Bypass Surgery | kidney failure | Acetylcysteine (NPC248970) | NP level |
NCT04557215 | Efficacy and Safety of Rifaximin With NAC in IBS-D | irritable bowel syndrome | Acetylcysteine (NPC248970) | NP level |
NCT01878695 | Pilot Study of Anti-oxidant Supplementation With N-Acetyl Cysteine in Stage 0/I Breast Cancer | breast cancer | Acetylcysteine (NPC248970) | NP level |
NCT01537926 | Hypertrophic Regression With N-Acetylcysteine in HCM | hypertrophic cardiomyopathy | Acetylcysteine (NPC248970) | NP level |
NCT00539513 | N-Acetylcysteine Augmentation in Treatment-Refractory Obsessive-Compulsive Disorder | obsessive-compulsive disorder | Acetylcysteine (NPC248970) | NP level |
NCT02688361 | A Bioequivalence Study of an Acetylcysteine 2% Oral Solution Versus a Reference Fluimucil 2% Oral Solution | respiratory tract infectious disorder | Acetylcysteine (NPC248970) | NP level |
NCT00203099 | Safety and Efficacy Study of Copaxone Administered in Combination With N-Acetylcysteine | multiple sclerosis | Acetylcysteine (NPC248970) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
NCT00136825,NCT00218491,NCT02141620,NCT02994875,NCT04155632,NCT03556371,NCT03423667
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
NCT00627705,NCT00676195,NCT05494398,NCT03008889,NCT00453180,NCT04278898
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04545008,NCT04374461,NCT04792021,NCT04703036,NCT04370288,NCT04928495
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
NCT04312594,NCT04300920,NCT02707640,NCT03720483,NCT00639496,NCT00650091
|
Cannabis use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C41 |
NCT01439828,NCT01675661,NCT03055377,NCT03154580,NCT01005810,NCT00542750
|
Alcohol dependenceDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40.2 |
NCT04964843,NCT03707951,NCT03216954,NCT01214083,NCT03120468,NCT00568087
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
BLM,TERT,SNCA,ALOX15,ABCB1
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NFKB1
NCT00203099,NCT05122559,NCT01381354 |
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SNCA
NCT03104725,NCT02212678,NCT01470027 |
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
NCT03730064,NCT02294591,NCT01797575,NCT05340504
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
TERT,ALOX15,ALPL,HSD17B10
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
TERT,ALOX15,THRB,ALPL
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
BLM,TERT,THRB,HSD17B10
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
ALOX15,TERT,ABCB1,SNCA
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
BLM,TERT,ALOX15,ALPL
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
ABCB1,TERT,NFKB1
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
TERT
NCT03121989,NCT01878695 |
Immune thrombocytopenic purpuraDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64.10 |
NCT03460808,NCT01808521,NCT04368598
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
NCT02737358,NCT02723162,NCT00751257
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
NCT01885338,NCT01506765,NCT03149107
|
Obsessive-compulsive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B20 |
NCT01555970,NCT00539513,NCT01172275
|
Symptoms and signs involving cognition, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.Z |
NCT00611897,NCT03306979,NCT03493178
|
Stimulant dependence including amphetamines, methamphetamine or methcathinoneDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C46.2 |
NCT04405193,NCT00332605,NCT01063205
|
Hearing disorderDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB50-AB57 |
NCT01131468,NCT00552786,NCT01271088
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
BLM,ALOX15,TERT
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
BLM,TERT,TERT
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
BLM,ALOX15,TERT
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ALOX15,ABCB1,THRB
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
NFKB1,ALOX15,HSD17B10
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
BLM,SNCA,THRB
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
BLM,TERT,SNCA
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
ABCB1,TERT
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
SNCA
NCT04740580 |
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NFKB1
NCT00609102 |
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
TERT,NFKB1
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
NCT00004467 |
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
TERT
NCT01612221 |
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1
NCT04557215 |
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
NCT03391856,NCT05123365
|
Common cold disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SA60 |
NCT05070650,NCT02379637
|
Alcoholic hepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB94.1 |
NCT00863785,NCT00962442
|
Becker muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.0 |
NCT03236662,NCT01856868
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
NCT03862586,NCT05460858
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
NCT03164421,NCT02775734
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
NCT03680911,NCT03679442
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT00809094,NCT00996424
|
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT01849016,NCT01800526
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
NCT00736866,NCT00211653
|
TrichotillomaniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B25.0 |
NCT00354770,NCT00993265
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
NCT03241472,NCT02493933
|
Neuropathy, ataxia, and retinitis pigmentosaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C73.1 |
NCT04864496,NCT03063021
|
Neurofibromatosis type 1Disease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2D.10 |
NCT04481035,NCT04481048
|
Diseases of the visual system, unspecifiedDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9E1Z |
NCT01015209,NCT01753752
|
Intracranial injury, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.Z |
NCT01322009,NCT04291066
|
Other specified sphingolipidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C56.0Y |
NCT00975689,NCT02583672
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
BLM,SNCA
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
BLM,TERT
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
BLM,ALPL
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
TERT,TERT
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
BLM,TERT
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
BLM,TERT
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
ALOX15,TERT
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
BLM,TERT
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
BLM,TERT
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT00440869,NCT00497328,NCT01210456,NCT01251029,NCT01017796,NCT00575419,NCT00830193,NCT04916080,NCT00780962,NCT00998972,NCT02088502,NCT01232257,NCT00506506,NCT01704482,NCT03636932
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
ALPL
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
TERT
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
THRB
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NFKB1
|
ThrombocytosisDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B63 |
TERT
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
TERT
|
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
TERT
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
NFKB1
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
TERT
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NFKB1
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
TERT
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
NFKB1
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
ABCB1
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
TERT
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
TERT
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
THRB
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
TERT
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NFKB1
|
Genetic prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E02 |
ALPL
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
THRB
|
Parasitic infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D0Y-1G2Z |
ALPL
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
TERT
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
NFKB1
|
Autonomic nervous system disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87 |
SNCA
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
TERT
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NFKB1
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
TERT
|
Preterm newborn, unspecifiedDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA21.4Z |
NCT03596125
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT03730064
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT00463749
|
Transposition of the great arteriesDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA85.1 |
NCT00374088
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT03346681
|
Acute pyelonephritisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB51 |
NCT02080182
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT03956888
|
Drug-induced or toxic liver disease, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB95.Z |
NCT01118663
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
NCT01082445
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
NCT05081479
|
Respiratory system diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB40-CB7Z |
NCT03843541
|
Idiopathic rhabdomyolysisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB32.20 |
NCT00391911
|
Ischaemia reperfusion injury of liverDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB98.B |
NCT01771978
|
Other specified primary disorders of musclesDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C7Y |
NCT02505087
|
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT02269540
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
NCT04918719
|
BacteraemiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MA15.0 |
NCT02040818
|
Noise effects on inner earDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB37 |
NCT02259595
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
NCT03702738
|
Other specified syndromes with multiple structural anomalies, not of environmental originDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F.1Y |
NCT04381897
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT02750319
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
NCT05485558
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT01880866
|
Hepatic veno-occlusive diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB98.6 |
NCT04712435
|
Disorders of peroxisomal alpha-, beta- or omega-oxidationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C57.1 |
NCT01495260
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT01384591
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
NCT04920448
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
NCT01063205
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
NCT04732000
|
Drug-induced or toxic liver disease with chronic hepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB95.1 |
NCT02182167
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
NCT01664260
|
Thrombotic thrombocytopenic purpuraDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64.14 |
NCT01808521
|
Diseases of the nervous systemDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 08 |
NCT04987775
|
Diseases of the blood or blood-forming organs, unspecifiedDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3C0Z |
NCT03252925
|
Biliary atresiaDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB95.1 |
NCT03499249
|
Chronic widespread painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30.01 |
NCT04594733
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT00428883
|
Bulimia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B81 |
NCT01033149
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
NCT00775476
|
Acute myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41 |
NCT01741207
|
Tourette syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A05.00 |
NCT01172288
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
NCT02688361
|
Acute ST elevation myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41.0 |
NCT04023266
|
Beta thalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50.2 |
NCT04260516
|
Polycythaemia veraDisease Category: X.Extension CodesDisease ICD-11 Code: XH0453 |
NCT05123365
|
Neuropathic painDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43.0 |
NCT01840345
|
Autism spectrum disorder without disorder of intellectual development and with mild or no impairment of functional languageDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02.0 |
NCT00453180
|
Oral mucositisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01 |
NCT04756622
|
Chronic bronchitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA20.1 |
NCT00205647
|
Other specified effects of air pressure or water pressureDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NF04.Y |
NCT01187108
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT01878669
|
Disorders of methionine cycle or sulphur amino acid metabolismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.B |
NCT00483314
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
NCT04123405
|
Injury of lung, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NB32.3Z |
NCT00655928
|
Graft-versus-host diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B24 |
NCT04945096
|
Alcohol beverageDisease Category: X.Extension CodesDisease ICD-11 Code: XM1A61 |
NCT03238300
|
Mental/behavioural/neurodevelopmental disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20-6E8Z |
NCT01354132
|
MyelofibrosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A22 |
NCT05123365
|
Pseudomyxoma peritoneiDisease Category: X.Extension CodesDisease ICD-11 Code: XH83J5 |
NCT04982146
|
Endothelial corneal dystrophyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A70.0 |
NCT04440280
|
Hypertrophic cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.1 |
NCT01537926
|
Diseases of neuromuscular junction or muscle, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D0Z |
NCT02362425
|
Other specified inborn errors of energy metabolismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C53.Y |
NCT05241262
|
Melanoma of skin, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30.Z |
NCT00003346
|
Cardiac arrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC9Z |
NCT04154982
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
ALPL
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
ALPL
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
ALPL
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
BLM
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
TERT
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
NFKB1
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
TERT
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
SNCA
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
ALPL
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
BLM
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
TERT
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
BLM
|