Astringent; Bitter; Cholagogue; Diaphoretic; Diuretic; Emetic; Emmenagogue; Hepatic; Homeopathy; Stimulant; Stomachic; Tonic
Brazil; Afghanistan; Italy; Peru; Canada; Kuwait; France; Netherlands; Ireland; Argentina; Norway; Ecuador; Turkmenistan; Israel; Australia; Iran; Algeria; Turkey; Jordan; China; Chile; Belgium; Germany; Kazakhstan; Poland; Spain; Georgia; Libya; Denmark; Philippines; Indonesia; Saudi Arabia; United States; Morocco; Sweden; Belarus; Croatia; Thailand; Switzerland; New Zealand; Russia; Bulgaria; Pakistan; Portugal; Uruguay; Egypt; India; United Kingdom; Tunisia; Austria; Vietnam; Paraguay; Hungary; Taiwan; Cyprus
Ingredient ID: NPC96312
Ingredient ID: NPC95463
Ingredient ID: NPC7688
Ingredient ID: NPC75356
Ingredient ID: NPC74824
Ingredient ID: NPC72787
Ingredient ID: NPC71708
Ingredient ID: NPC7154
Ingredient ID: NPC65149
Ingredient ID: NPC5989
Ingredient ID: NPC58223
Ingredient ID: NPC56229
Ingredient ID: NPC51304
Ingredient ID: NPC50934
Ingredient ID: NPC479118
Ingredient ID: NPC479117
Ingredient ID: NPC45000
Ingredient ID: NPC37321
Ingredient ID: NPC36916
Ingredient ID: NPC36
Ingredient ID: NPC319430
Ingredient ID: NPC311485
Ingredient ID: NPC298344
Ingredient ID: NPC289803
Ingredient ID: NPC281011
Ingredient ID: NPC280834
Ingredient ID: NPC279311
Ingredient ID: NPC279209
Ingredient ID: NPC26253
Ingredient ID: NPC260317
Ingredient ID: NPC260257
Ingredient ID: NPC258668
Ingredient ID: NPC252084
Ingredient ID: NPC247525
Ingredient ID: NPC246162
Ingredient ID: NPC244903
Ingredient ID: NPC244128
Ingredient ID: NPC243871
Ingredient ID: NPC238063
Ingredient ID: NPC237093
Ingredient ID: NPC226955
Ingredient ID: NPC223695
Ingredient ID: NPC219977
Ingredient ID: NPC217795
Ingredient ID: NPC208620
Ingredient ID: NPC206577
Ingredient ID: NPC192396
Ingredient ID: NPC185497
Ingredient ID: NPC183953
Ingredient ID: NPC179960
Ingredient ID: NPC179694
Ingredient ID: NPC174347
Ingredient ID: NPC172609
Ingredient ID: NPC170590
Ingredient ID: NPC170028
Ingredient ID: NPC167646
Ingredient ID: NPC162872
Ingredient ID: NPC159720
Ingredient ID: NPC155185
Ingredient ID: NPC153843
Ingredient ID: NPC151423
Ingredient ID: NPC138688
Ingredient ID: NPC125732
Ingredient ID: NPC125731
Ingredient ID: NPC125039
Ingredient ID: NPC112701
Ingredient ID: NPC102277
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Drug Transporter | ATP-binding cassette | ABCB11 | Bile salt export pump | O95342 | CHEMBL6020 |
Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
Therapeutic Target | Nuclear hormone receptor subfamily 1 | PPARG | Peroxisome proliferator-activated receptor gamma | P37231 | CHEMBL235 |
Therapeutic Target | Oxidoreductase | MAOB | Monoamine oxidase B | P27338 | CHEMBL2039 |
Therapeutic Target | Protein Kinase | PRKCA | Protein kinase C alpha | P17252 | CHEMBL299 |
Therapeutic Target | Protein Kinase | PRKCE | Protein kinase C epsilon | Q02156 | CHEMBL3582 |
Therapeutic Target | Protein Kinase | PRKCB | Protein kinase C beta | P05771 | CHEMBL3045 |
Therapeutic Target | Protein Kinase | PRKCG | Protein kinase C gamma | P05129 | CHEMBL2938 |
Drug Transporter | SLC superfamily of solute carriers | SLCO2B1 | Solute carrier organic anion transporter family member 2B1 | O94956 | CHEMBL1743124 |
Therapeutic Target | Small molecule receptor (family A GPCR) | TAAR1 | Trace amine-associated receptor 1 | Q96RJ0 | CHEMBL5857 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 21 | |
Plant level | 12 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00915681 | Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning | Hepatic failure | Silibinin (NPC36916) | NP level |
NCT05076058 | Effects of Tablets of Silybum Marianum;Pueraria Lobate and Salvia Miltiorrhiza on Fatty Liver | Fatty Liver Disease | Silybum Marianum | Plant level As single plant |
NCT00412763 | Efficacy of Silymarin for Acute Hepatitis | Hepatitis | Silybum Marianum | Plant level As plant Extract |
NCT01292161 | Effects of Silybum Marianum on Treatment of Patients With Chronic Hepatitis C | hepatitis C virus infection | Silybin A (NPC7154) | NP level |
NCT00680342 | Phase II Trial of Silymarin for Patients With Chronic Hepatitis C Who Have Failed Conventional Antiviral Treatment | Chronic Hepatitis C | Silybum Marianum | Plant level As plant Extract |
NCT01258686 | Clinical Study With Silymarin in the Patients With Chronic Hepatitis C Infection Who Failed Conventional Antiviral Therapy | hepatitis C virus infection | Silybin A (NPC7154) | NP level |
NCT00680407 | Phase II Trial of Silymarin for Non-Cirrhotic Patients With Non-Alcoholic Steatohepatitis | Non-alcoholic Steatohepatitis | Silybum Marianum | Plant level As plant Extract |
NCT00487721 | The Effect of High-dose Silybin-phytosome in Men With Prostate Cancer | prostate cancer | Silibinin (NPC36916) | NP level |
NCT01129570 | Siliphos in Advanced Hepatocellular Carcinoma | hepatocellular carcinoma | Silybin A (NPC7154) | NP level |
NCT01009931 | Phase II Study of TPA Plus Dexamethasone & CMT in Hematologic Malignancies | leukemia | Phorbol Myristate Acetate (NPC5989) | NP level |
NCT03982849 | Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma | freckles | Silybin A (NPC7154) | NP level |
NCT00755950 | Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis | hepatitis A virus infection;hepatitis B virus infection;hepatitis E virus infection;hepatitis C virus infection | Silybin A (NPC7154) | NP level |
NCT01829178 | Evaluation of Effects of Silymarin on Cisplatin Induced Nephrotoxicity in Upper Gastrointestinal Adenocarcinoma | cancer | Silybin A (NPC7154) | NP level |
NCT01091324 | Dextromethorphan and Silymarin in Chronic Kidney Disease (CKD) Patients | Proteinuria | Silybin A (NPC7154) | NP level |
NCT01049178 | Randomized Controlled Trial of Silymarin in Asthma | Atopic Asthma | Silybum Marianum | Plant level As plant Extract |
NCT01535092 | Legalon SIL for the Treatment of HCV Recurrence in Liver Transplanted Patients | hepatitis C virus infection | Silibinin (NPC36916) | NP level |
NCT00011635 | The Effect of Milk Thistle on the Pharmacokinetics of Indinavir | HIV Infection|Healthy | Silybum Marianum | Plant level As single plant |
NCT00915681 | Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning | Amatoxin Poisoning|Amanita Poisoning|Mushroom Poisoning|Liver Failure | Silybum Marianum | Plant level As plant Extract |
NCT00684268 | Intravenous Silibinin in Combination With Peg-interferon and Ribavirin in Nonresponders | hepatitis C virus infection | Silibinin (NPC36916) | NP level |
NCT01795924 | Safety and Efficacy Study of PD-616 Plus Cytarabine to Treat Acute Myelogenous Leukemia or Myelodysplastic Syndrome | acute myeloid leukemia;myelodysplastic syndrome | Phorbol Myristate Acetate (NPC5989) | NP level |
NCT00748059 | The Pathophysiology of Orthostatic Hypotension | orthostatic hypotension;orthostatic intolerance | Tyramine (NPC125732) | NP level |
NCT01829178 | Evaluation of Effects of Silymarin on Cisplatin Induced Nephrotoxicity in Upper Gastrointestinal Adenocarcinoma | Upper GI Cancer|Cisplatin Adverse Reaction | Silybum Marianum | Plant level As plant Extract |
NCT00680342 | Phase II Trial of Silymarin for Patients With Chronic Hepatitis C Who Have Failed Conventional Antiviral Treatment | chronic hepatitis C virus infection | Silybin A (NPC7154) | NP level |
NCT00203125 | A Study to Evaluate the Effects of Tyramine in Patients Who Completed the PRESTO Study. | Parkinson disease | Tyramine (NPC125732) | NP level |
NCT00200798 | An Assessment of Milk Thistle Pharmacokinetics and Drug Interactions | Healthy | Silybum Marianum | Plant level As single plant |
NCT00680407 | Phase II Trial of Silymarin for Non-Cirrhotic Patients With Non-Alcoholic Steatohepatitis | non-alcoholic fatty liver disease | Silybin A (NPC7154) | NP level |
NCT01957319 | Silybin Supplementation During HCV Therapy With Pegylated Interferon-α2b Plus Ribavirin Reduces Depression and Increases Work Ability | depressive disorder | Silybin A (NPC7154) | NP level |
NCT01752153 | Immunomodulatory Effects of Silymarin in Patients With Beta-Thalassemia Major | immune system disease | Silybin A (NPC7154) | NP level |
NCT03687073 | Trial of Indole-3-Carbinol and Silibinin | nicotine dependence | Silibinin (NPC36916) | NP level |
NCT01518933 | Effect of LEGALON SIL on Hepatitis C Virus Recurrence in Stable Liver Transplanted Patients | hepatitis C virus infection | Silibinin (NPC36916) | NP level |
NCT01018615 | Safety;Metabolism;and Antioxidant Activity of Silymarin and Green Tea Extract in Patients With Chronic Hepatitis C | Chronic Hepatitis C|Oxidative Stress | Silybum Marianum | Plant level As plant Extract |
NCT01001845 | Comparative Effects of Milk Thistle Extract With Vitamin-E in Hemodialysis Patients | Hemodialysis|End Stage Renal Disease | Silybum Marianum | Plant level As plant Extract |
NCT01003236 | Evaluating the Renoprotective Effect of Milk Thistle Extract on Patients With Type II Diabetic Nephropathy | Diabetic Nephropathy | Silybum Marianum | Plant level As plant Extract |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT00680342,NCT01018615
NCT01518933,NCT00755950,NCT01258686,NCT01535092,NCT01292161,NCT00684268,NCT00680342 |
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
PRKCD,PRKCG,MAOB,ABCB11,CISD1,PPARG,CA7,PRKCB,LMNA
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
PRKCE,PRKCG,PRKCQ,PRKCD,CISD1,CA12,PRKCB
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
PRKCG,PRKCQ,PRKCA,CA12,CA7,PRKCB,LMNA
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
PPARG
PRKCE NCT00680407,NCT05076058 NCT00680407 |
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
PRKCG,PRKCQ,ABCB11,CISD1,CA7
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
PRKCG,PRKCQ,RASGRP3,SLCO2B1,PRKCB
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
MAOB,CISD1,SLCO2B1,CA12,LMNA
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
PRKCG,PRKCQ,PRKCA,SLCO2B1,PRKCB
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
PRKCD,PRKCG,PRKCA,LMNA
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
PRKCQ,PRKCA,RASGRP3,SLCO2B1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
PRKCQ,CA12,CA7,PRKCB
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
PRKCB,PPARG,CA12
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
PRKCE,MAOB,PPARG
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
TAAR1,MAOB
NCT00203125 |
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
PRKCA,PRKCB,PRKCQ
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
PRKCE,PRKCG,PRKCB
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
PRKCG,CA12,CA7
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
PRKCB,PRKCG,PRKCQ
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
CA12,CA7,PRKCG
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
PPARG,SLCO2B1,LMNA
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
PRKCG,CISD1,PRKCB
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
SLCO2B1,CA12,LMNA
|
Harmful effects of unspecified substanceDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
NCT00915681,NCT00915681
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT01018615
NCT00748059 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
PPARG,MAOB
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
TAAR1,MAOB
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
PRKCG
NCT01795924 |
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
PRKCE,MAOB
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
MAOB
NCT00487721 |
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
PPARG
NCT03687073 |
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
CA12,PRKCQ
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
PRKCG,SLCO2B1
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
PRKCQ,PRKCE
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
CA12,CA12
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
PRKCA,LMNA
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CA12,CA7
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
PRKCD,CA12
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
CA12,RASGRP3
|
Neoplasms of unknown behaviour of oral cavity and digestive organs, unspecified siteDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F90.Z |
NCT01829178
|
Hepatic failure without mention whether acute or chronicDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB99.7 |
NCT00915681
|
Poisonous mushroomDisease Category: X.Extension CodesDisease ICD-11 Code: XM74S8 |
NCT00915681
|
Chronic kidney disease, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.Z |
NCT01003236
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
NCT01049178
|
Acute viral hepatitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50 |
NCT00412763
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT00011635
|
Chronic kidney disease, stage 5Disease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.5 |
NCT01001845
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PPARG
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA12
|
Liver vascular disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB98 |
PRKCE
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
MAOB
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
PPARG
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
MAOB
|
Skin tag/polypDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK71 |
MAOB
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
PRKCG
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
PRKCE
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA12
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
MAOB
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
PRKCB
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
TAAR1
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
PPARG
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
PRKCB
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
TAAR1
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
MAOB
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
PPARG
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
MAOB
|
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
PRKCA
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
PPARG
|
Opioid use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C43 |
PPARG
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
PPARG
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
PPARG
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
PRKCG
|
Focal/segmental autonomic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D8A |
TAAR1
|
Skin cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30-2C37 |
MAOB
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
PRKCD
|
MastocytosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21 |
PRKCG
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
MAOB
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
PRKCB
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
PPARG
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
PRKCB
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
PPARG
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
PRKCB
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
PPARG
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA12
|
Sjogren syndromeDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A43 |
PPARG
|
Primary psychotic disorder manifestationDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A25 |
MAOB
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
PRKCB
|
NarcolepsyDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A20 |
TAAR1
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
NCT00755950
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NCT00915681
|
Acute hepatitis ADisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50.0 |
NCT00755950
|
Immune system diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01-4B41 |
NCT01752153
|
ProteinuriaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF96 |
NCT01091324
|
Chronic hepatitis B, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.0Z |
NCT00755950
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT01129570
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT01957319
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
NCT01795924
|
FrecklesDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED61.0 |
NCT03982849
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
NCT00748059
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT01829178
|
LeukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2B33 |
NCT01009931
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
PRKCG
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
PRKCG
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
PRKCG
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CA12
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
PRKCG
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
CA12
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
SLCO2B1
|