CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Silybum Marianum

Example Image

PLANiTS DNA barcode

Click for details-----ITS

GGTCGTTTGCTGTGCAGCTCGACAATGATCCGTATGTGACTGCGGAAGGATCATTGTCGAAGCCTGCACAGCAGAACGACCCGCGAACACGTAATCACAGCCGGGCGTCGAGGGGGTCGGGCGTGAGCCCGGTGCCCGCGATGCCTTGTCGACGTGCGTCTGCGATGCCCCGTTTCGAGGCGTCGTGGATGTTGCGTCGGCACCTAAACAAACCCCGGCACGGCATGTGCCAAGGAAAACAAAACATATGAAGGGTGCGTCTCGTGTTGCCCCGTTCGCGGTGCGCGCACGGGCCGTGGCCTCTCAATAACCATAAACGACTCTCGGCAACGGATATCTCGGCTCACGCATCGATGAAGAACGTAGCAAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTTTTTGAACGCAAGTTGCGCCCGAAGCCATTCGGCCGAGGGCACGTCTGCCTGGGCGTCACGCATCGCGTCGCCCCAGACCACGCCTTCCCTACGGGGATGCGTTCGTCTGGGGCGGAGAATGGTCTCCCGTGCCGTCGGCGCGGTTGGCCTAAAAAGGAGTCCCCTTCGACGGACGCACGGCTAGTGGTGGTTGTTAAGGCCTTCGTATCGAGCCGTGTGTCGTTAGCCGCAAGGGAAGCGCTCTCCAAAGACCCCAACGCGTCGTCTCGCGACGATGCTNCGA

Click for details-----ITS1

Click for details-----ITS2

ATCGCGTCGCCCCAGACCACGCCTTCCCTACGGGGATGCGTTCGTCTGGGGCGGAGAATGGTCTCCCGTGCCGTCGGCGCGGTTGGCCTAAAAAGGAGTCCCCTTCGACGGACGCACGGCTAGTGGTGGTTGTTAAGGCCTTCGTATCGAGCCGTGTGTCGTTAGCCGCAAGGGAAGCTGCTCTCCAAAGACCCCAACGCTGTCGTCTCGCGACGATGCTTCGACC

Taxonomic Information

Plant ID: NPO5645
Plant Latin Name: Silybum Marianum
Taxonomy Genus: Silybum
Taxonomy Family: Asteraceae

Plant External Links:

NCBI TaxonomyDB: 92921
Plant-of-the-World-Online: 249211-1

Used in Medicines

Country/Region:

Pakistan; Israel; Italy; Turkmenistan; India; China; Croatia; Jordan; Spain; Bulgaria

Traditional Medicine System:

TCM; Homeopathy

Medicinal Functions:

Astringent; Bitter; Cholagogue; Diaphoretic; Diuretic; Emetic; Emmenagogue; Hepatic; Homeopathy; Stimulant; Stomachic; Tonic

Geographical Distribution

Brazil; Afghanistan; Italy; Peru; Canada; Kuwait; France; Netherlands; Ireland; Argentina; Norway; Ecuador; Turkmenistan; Israel; Australia; Iran; Algeria; Turkey; Jordan; China; Chile; Belgium; Germany; Kazakhstan; Poland; Spain; Georgia; Libya; Denmark; Philippines; Indonesia; Saudi Arabia; United States; Morocco; Sweden; Belarus; Croatia; Thailand; Switzerland; New Zealand; Russia; Bulgaria; Pakistan; Portugal; Uruguay; Egypt; India; United Kingdom; Tunisia; Austria; Vietnam; Paraguay; Hungary; Taiwan; Cyprus

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

67 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

23 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)