Collective Molecular Activities of the Plant: Allium Macrostemon
Country/Region:
ChinaTraditional Medicine System:
TCMMedicinal Functions:
Astringent; Carminative; Depurative; Diuretic; Emmenagogue; Nervine; Tonic
Japan; China; Russia; Mongolia; South Africa
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
85 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
59 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
39 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC96337
Ingredient ID: NPC95064
Ingredient ID: NPC91295
Ingredient ID: NPC88603
Ingredient ID: NPC86191
Ingredient ID: NPC8288
Ingredient ID: NPC78551
Ingredient ID: NPC76145
Ingredient ID: NPC7479
Ingredient ID: NPC74749
Ingredient ID: NPC71703
Ingredient ID: NPC69807
Ingredient ID: NPC69678
Ingredient ID: NPC67681
Ingredient ID: NPC67118
Ingredient ID: NPC63324
Ingredient ID: NPC4884
Ingredient ID: NPC47778
Ingredient ID: NPC42150
Ingredient ID: NPC34764
Ingredient ID: NPC33415
Ingredient ID: NPC312151
Ingredient ID: NPC30292
Ingredient ID: NPC300596
Ingredient ID: NPC298093
Ingredient ID: NPC297987
Ingredient ID: NPC296651
Ingredient ID: NPC291502
Ingredient ID: NPC289758
Ingredient ID: NPC288885
Ingredient ID: NPC286347
Ingredient ID: NPC285364
Ingredient ID: NPC284743
Ingredient ID: NPC277475
Ingredient ID: NPC275716
Ingredient ID: NPC273959
Ingredient ID: NPC270088
Ingredient ID: NPC254416
Ingredient ID: NPC252300
Ingredient ID: NPC239548
Ingredient ID: NPC231893
Ingredient ID: NPC231323
Ingredient ID: NPC230549
Ingredient ID: NPC225255
Ingredient ID: NPC220140
Ingredient ID: NPC217372
Ingredient ID: NPC21209
Ingredient ID: NPC209389
Ingredient ID: NPC208956
Ingredient ID: NPC2088
Ingredient ID: NPC204840
Ingredient ID: NPC203468
Ingredient ID: NPC200137
Ingredient ID: NPC196733
Ingredient ID: NPC192007
Ingredient ID: NPC190810
Ingredient ID: NPC184203
Ingredient ID: NPC183925
Ingredient ID: NPC183662
Ingredient ID: NPC180340
Ingredient ID: NPC176017
Ingredient ID: NPC174406
Ingredient ID: NPC16997
Ingredient ID: NPC165549
Ingredient ID: NPC163529
Ingredient ID: NPC157340
Ingredient ID: NPC156461
Ingredient ID: NPC156018
Ingredient ID: NPC15573
Ingredient ID: NPC154191
Ingredient ID: NPC149155
Ingredient ID: NPC149081
Ingredient ID: NPC146250
Ingredient ID: NPC144939
Ingredient ID: NPC13991
Ingredient ID: NPC137739
Ingredient ID: NPC136893
Ingredient ID: NPC136237
Ingredient ID: NPC134252
Ingredient ID: NPC130734
Ingredient ID: NPC12036
Ingredient ID: NPC114239
Ingredient ID: NPC113212
Ingredient ID: NPC113203
Ingredient ID: NPC110233
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 2 | CYP2D6 | Cytochrome P450 2D6 | P10635 | CHEMBL289 |
| Therapeutic Target | Enzyme | MIF | Macrophage migration inhibitory factor | P14174 | CHEMBL2085 |
| Therapeutic Target | Methyl-lysine/arginine binding protein | SMN1 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
| Therapeutic Target | Other cytosolic protein | MAPT | Microtubule-associated protein tau | P10636 | CHEMBL1293224 |
| Therapeutic Target | Oxidoreductase | ND4 | NADH-ubiquinone oxidoreductase chain 4 | P03905 | CHEMBL4499 |
| Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
| Therapeutic Target | Protein Kinase | MTOR | Serine/threonine-protein kinase mTOR | P42345 | CHEMBL2842 |
| Therapeutic Target | Protein Kinase | GSK3B | Glycogen synthase kinase-3 beta | P49841 | CHEMBL262 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADORA2A | Adenosine A2a receptor | P29274 | CHEMBL251 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADORA3 | Adenosine A3 receptor | P0DMS8 | CHEMBL256 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADORA1 | Adenosine A1 receptor | P30542 | CHEMBL226 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | HTR6 | Serotonin 6 (5-HT6) receptor | P50406 | CHEMBL3371 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Transferase | TERT | Telomerase reverse transcriptase | O14746 | CHEMBL2916 |
| Therapeutic Target | Transient receptor potential channel | TRPA1 | Transient receptor potential cation channel subfamily A member 1 | O75762 | CHEMBL6007 |
| Therapeutic Target | Unclassified protein | PMP22 | Peripheral myelin protein 22 | Q01453 | CHEMBL1293298 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 137 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT01251770 | Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
| NCT01485315 | Transfusion-requirements in Septic Shock Trial | septic shock | Glucose, Liquid (NPC289758) | NP level |
| NCT01575405 | A Study to Compare Three Different Formulations of Tenofovir 1% Gel When Administered Rectally | HIV infection | Glycerin (NPC157340) | NP level |
| NCT00000324 | Tryptophan and Behavior Therapy for Cocaine Abuse - 1 | cocaine dependence | Tryptophan (NPC203468) | NP level |
| NCT03205553 | Direct Peritoneal Resuscitation in Gastroschisis | gastroschisis | Glucose, Liquid (NPC289758) | NP level |
| NCT04677829 | Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI) | brain injury | Glucose, Liquid (NPC289758) | NP level |
| NCT02866435 | Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
| NCT04392622 | d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma | xerostomia | Limonene (NPC76145) | NP level |
| NCT00617981 | Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC) | hepatocellular carcinoma | Glucose, Liquid (NPC289758) | NP level |
| NCT02681913 | Adenosine as an Adjunct to Blood Cardioplegia | cardiomyopathy | Adenosine (NPC156461) | NP level |
| NCT05014061 | Adenosine's Effect on STunning Resolution in Acute Myocardial Infarction | Myocardial Ischemia | Adenosine (NPC156461) | NP level |
| NCT01223690 | Clarithromycin as Immunomodulator for the Management of Sepsis | Sepsis;septic shock | Glucose, Liquid (NPC289758) | NP level |
| NCT00751491 | Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI) | angina pectoris | Adenosine (NPC156461) | NP level |
| NCT02044341 | Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media | Otitis media | Glycerin (NPC157340) | NP level |
| NCT02067975 | Tryptophan MRI in People With Schizophrenia and Healthy Controls | schizophrenia | Tryptophan (NPC203468) | NP level |
| NCT00179010 | AMP as a Better Delivery System of Adenosine | ischemia | Adenosine (NPC156461) | NP level |
| NCT03860688 | Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins | hyperlipidemia | Glucose, Liquid (NPC289758) | NP level |
| NCT01788969 | Serotonergic Modulation of Motor Function in Subacute and Chronic SCI | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
| NCT02910518 | A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT03901144 | A NOVel Moisturiser for Atopic Dermatitis: Effect on the Skin Barrier | atopic eczema | Glycerin (NPC157340) | NP level |
| NCT02269735 | A Three-part Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-2640 in Healthy Participants (Part I) and Participants With Type 1 Diabetes Mellitus (Parts II and III) (MK-2640-001) | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT04853082 | Limonene on Regulating Metabolism-related Fatty Liver Disease (MAFLD) and Analysis of TCM Constitution | Hepatic steatosis | Limonene (NPC76145) | NP level |
| NCT02936830 | Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity | allergic disease | Glycerin (NPC157340) | NP level |
| NCT00213759 | Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSF | neutropenia | Glucose, Liquid (NPC289758) | NP level |
| NCT05029037 | High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. | COVID-19 | Glucose, Liquid (NPC289758) | NP level |
| NCT01557296 | Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
| NCT00580606 | A Randomized, Double-Blind Placebo-Controlled Peanut Sublingual Immunotherapy Trial | peanut allergic reaction | Glycerin (NPC157340) | NP level |
| NCT02591927 | Reappraisal of GIK in Acute STEMI by Pre-hospital Administration | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
| NCT00622440 | Treatment of Anal High-grade Squamous Intraepithelial Lesions (HSIL) Through Use of a Chinese Herbal Topical Cream | anal neoplasm | Indigo (NPC209389) | NP level |
| NCT00781404 | Myocardial Protection With Adenosine During Primary Percutaneous Coronary Intervention in Pts With STEMI | acute myocardial infarction | Adenosine (NPC156461) | NP level |
| NCT00337597 | Continuous Regional Analgesia After Total Knee Arthroplasty | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT02752308 | Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair | hypospadias | Glucose, Liquid (NPC289758) | NP level |
| NCT01123525 | Adenosine Cardioplegia | angina pectoris | Adenosine (NPC156461) | NP level |
| NCT01747174 | REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction | ST Elevation Myocardial Infarction | Adenosine (NPC156461) | NP level |
| NCT02632630 | Nutrition Supplementation in Hospitalized Patients | malnutrition | Glucose, Liquid (NPC289758) | NP level |
| NCT04001036 | Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
| NCT03039673 | MIROCALS: Modifying Immune Response and OutComes in ALS | amyotrophic lateral sclerosis | Glucose, Liquid (NPC289758) | NP level |
| NCT01075984 | Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for Invasive Fungal Infections (P05520) | fungal infectious disease | Glucose, Liquid (NPC289758) | NP level |
| NCT01932112 | Adenosine Effect on Persistent Pulmonary Vein Isolation Line Evaluation (APPLE Trial) | atrial fibrillation | Adenosine (NPC156461) | NP level |
| NCT00567931 | 1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT05424315 | Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
| NCT00298636 | Dose-Response of Adenosine for Perioperative Pain | pain | Adenosine (NPC156461) | NP level |
| NCT00841256 | Multicenter Trial of Sublingual Immunotherapy With a Solution of Grass Pollen Allergen Extract in Children | allergic conjunctivitis | Glycerin (NPC157340) | NP level |
| NCT00612014 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
| NCT03778593 | FOLFIRINOX for 2nd-line Treatment of BTC | biliary tract cancer | Glucose, Liquid (NPC289758) | NP level |
| NCT02867878 | Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo Syndrome | Takotsubo cardiomyopathy | Adenosine (NPC156461) | NP level |
| NCT02710266 | Evaluation of the Effect of Gabexate Mesilate in the Hepatocyte Protection After Liver Resection | liver disease | Glucose, Liquid (NPC289758) | NP level |
| NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Allicin (NPC2088) | NP level |
| NCT01300260 | Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose | type 2 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT00632775 | 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
| NCT02180412 | Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria | porphyria | Glucose, Liquid (NPC289758) | NP level |
| NCT01121354 | Pharmacokinetics and Safety of Cefazolin 2g in DUPLEX | infection | Glucose, Liquid (NPC289758) | NP level |
| NCT05326763 | Functional and Electromyographical Changes After PRP or Dextrose Injection in Chronic Lateral Epicondylitis | lateral epicondylitis | Glucose, Liquid (NPC289758) | NP level |
| NCT00062972 | Improving Memory in Patients With Multiple Sclerosis | multiple sclerosis | Glucose, Liquid (NPC289758) | NP level |
| NCT03994471 | Efficacy and Safety of XyloCore Peritoneal Dialysis Solution. | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
| NCT00845689 | Prevention of Liver Damage During Liver Surgery | neoplasm | Adenosine (NPC156461) | NP level |
| NCT04666454 | BROKEN-SWEDEHEART-Optimized Pharmacological Treatment for Broken Heart (Takotsubo) Syndrome | Takotsubo cardiomyopathy | Adenosine (NPC156461) | NP level |
| NCT02899169 | Treatment of Non-high-risk Acute Promyelocytic Leukemia (APL) With Realgar-Indigo Naturalis Formula (RIF) | acute promyelocytic leukemia | Indigo (NPC209389) | NP level |
| NCT05185999 | Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
| NCT03236311 | A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI | coronary artery disease | Adenosine (NPC156461) | NP level |
| NCT04409665 | The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST) | respiratory failure | Glucose, Liquid (NPC289758) | NP level |
| NCT05297123 | Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid Acid | acute myeloid leukemia | Indigo (NPC209389) | NP level |
| NCT03404869 | Study of ORL-1M (D-mannose) in Patients With CDG-Ib | congenital disorder of glycosylation | D-Mannose (NPC285364) | NP level |
| NCT00714103 | 8-Chloro-Adenosine in Chronic Lymphocytic Leukemia | chronic lymphocytic leukemia | Adenosine (NPC156461) | NP level |
| NCT03577730 | Caffeine and Neurologic Recovery Following Surgery and General Anesthesia | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT00552786 | Antioxidation Medication for Noise-induced Hearing Loss | hearing loss | Glucose, Liquid (NPC289758) | NP level |
| NCT03241706 | Liver Glycogen and Hypoglycemia in Humans | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
| NCT04726436 | Dextrose Effect on Postoperative Nausea and Vomiting (PONV) | post operative nausea and vomiting | Glucose, Liquid (NPC289758) | NP level |
| NCT04791202 | Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT03024814 | Prophylactic Acetaminophen for Prevention Intraventricular Hemorrhage in Premature Infants | hemorrhage | Glucose, Liquid (NPC289758) | NP level |
| NCT00565188 | Application of ATP Infusions in Palliative Home Care | cancer | Adenosine (NPC156461) | NP level |
| NCT00590070 | THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myocardial Infarction | myocardial infarction | Adenosine (NPC156461) | NP level |
| NCT01335386 | Investigation of KLYX in Patients With Constipation | Constipation | Glycerin (NPC157340) | NP level |
| NCT01548612 | Add-on Sodium Nitroprusside to Treatment as Usual in Schizophrenia | schizophrenia | Glucose, Liquid (NPC289758) | NP level |
| NCT00816504 | Effect of Galactose on Permeblity Factor in Patients With FSGS and CKD Stage 5 | focal segmental glomerulosclerosis | Galactose (NPC21209) | NP level |
| NCT01883440 | Glucose Oxidase as Treatment Against Common Cold | common cold | Glucose, Liquid (NPC289758) | NP level |
| NCT01909336 | Use of Isotonic Solutions Versus Hypotonic Solutions for Preventing Hospital Acquired Hyponatremia | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
| NCT00686608 | Hypothalamic Functional Magnetic Resonance Imaging (fMRI) Response to Nutrients | obesity | Glucose, Liquid (NPC289758) | NP level |
| NCT04832009 | Reversing Glucose and Lipid-mediated Vascular Dysfunction | hypertension | Glucose, Liquid (NPC289758) | NP level |
| NCT00091507 | IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium. | congestive heart failure;intermediate coronary syndrome;myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
| NCT01901705 | A Study of Topical Indigo Naturalis Treatment in Patients With Mild to Moderate Plaque-type Psoriasis | psoriasis | Indigo (NPC209389) | NP level |
| NCT04088591 | High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda | Sepsis | Glucose, Liquid (NPC289758) | NP level |
| NCT02728037 | Magnesium-Based Trigger Point Injections for Relief of Chronic Myofascial Pelvic Pain | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT01593644 | Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler | coronary artery disease | Adenosine (NPC156461) | NP level |
| NCT02319512 | Effects of Chewing Gum Against Postoperative Ileus | ileus | Glucose, Liquid (NPC289758) | NP level |
| NCT00284323 | Salvage: Postconditioning With Adenosine for STEMI | ST Elevation Myocardial Infarction | Adenosine (NPC156461) | NP level |
| NCT02185729 | Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunteers | metabolic disease | Glucose, Liquid (NPC289758) | NP level |
| NCT04588441 | The ARCTIC Trial: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19 | acute respiratory distress syndrome | Adenosine (NPC156461) | NP level |
| NCT00580905 | Role of Adenosine in the Release of VEGF and Cytokines | inflammation | Adenosine (NPC156461) | NP level |
| NCT04895358 | Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49) | breast neoplasm | Glucose, Liquid (NPC289758) | NP level |
| NCT04133922 | Effect of GLP-1 on Microvascular Insulin Responses in Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT02618824 | Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery | congenital heart disease | Tryptophan (NPC203468) | NP level |
| NCT01687218 | Safety and Acceptability Study of Oral Emtricitabine/Tenofovir Disoproxil Fumarate Tablet and Rectally-Applied Tenofovir Reduced-Glycerin 1% Gel | HIV infection | Glycerin (NPC157340) | NP level |
| NCT00691197 | Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear | Abnormality of refraction | Glycerin (NPC157340) | NP level |
| NCT04557878 | Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction | temporomandibular joint disorder | Glucose, Liquid (NPC289758) | NP level |
| NCT00823108 | Rapid Administration of Insulin in Sepsis | septic shock | Glucose, Liquid (NPC289758) | NP level |
| NCT03690583 | Immunomodulation by Zinc Supplementation in Children With Pneumonia | pneumonia | Glucose, Liquid (NPC289758) | NP level |
| NCT00003667 | Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma | sarcoma | Glycerin (NPC157340) | NP level |
| NCT01022502 | Comparison of Refined and Crude Indigo Naturalis Ointment in Treating Psoriasis | psoriasis vulgaris | Indigo (NPC209389) | NP level |
| NCT00800085 | Beta Cell Function in (Pre) Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT02054325 | Study Protocol Comparing Polidocanol Versus Hypertonic Glucose for Treatment of Reticular Veins | Varicose veins | Glucose, Liquid (NPC289758) | NP level |
| NCT02325583 | Intraoral 30% Glucose Effect In Newborns | epilepsy | Glucose, Liquid (NPC289758) | NP level |
| NCT03395288 | Nutraceutical Efficacy for rUTI | urinary tract infection | D-Mannose (NPC285364) | NP level |
| NCT01445886 | Comparison of Indigo Naturalis Oil Extract and Calcipotriol Solution in Treating Psoriasis | psoriasis | Indirubin (NPC300596) | NP level |
| NCT02110810 | Indomethacin Decreases Post-ERCP Pancreatitis | acute pancreatitis | Glycerin (NPC157340) | NP level |
| NCT01042535 | Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer | male breast carcinoma | Tryptophan (NPC203468) | NP level |
| NCT01191216 | 1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT05160532 | Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
| NCT00814255 | Novel Therapies for Resistant FSGS (FONTII): Phase II Clinical Trial | focal segmental glomerulosclerosis | Galactose (NPC21209) | NP level |
| NCT00835939 | Treatment for Achilles Tendinopathy | Tendinopathy | Glucose, Liquid (NPC289758) | NP level |
| NCT01474499 | A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation | Constipation | Glycerin (NPC157340) | NP level |
| NCT02088281 | Mechanistic Study of Indigo Naturalis in Treating Psoriasis | psoriasis vulgaris | Indirubin (NPC300596) | NP level |
| NCT01575418 | An Exploratory Rectal Safety Study of Three Tenofovir Gel Formulations | HIV infection | Glycerin (NPC157340) | NP level |
| NCT00999687 | Evaluation of the Efficacy and Safety of Indigo Naturalis Oil Extract on Psoriatic Nails | psoriasis | Indirubin (NPC300596) | NP level |
| NCT02374281 | Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT00612521 | Prophylactic Intra-coronary Adenosine to Prevent Post Coronary Artery Stenting Myonecrosis | coronary stenosis | Adenosine (NPC156461) | NP level |
| NCT03337477 | A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 | Hyperkalemia | Glucose, Liquid (NPC289758) | NP level |
| NCT02678208 | The Effect of Tranexamic Acid on Uterine Blood Flow After Vaginal Delivery | postpartum hemorrhage | Glucose, Liquid (NPC289758) | NP level |
| NCT04918719 | Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke | Ischemic stroke | Glucose, Liquid (NPC289758) | NP level |
| NCT02669888 | Indigo Naturalis in Treating Atopic Dermatitis Topically | atopic eczema | Indigo (NPC209389) | NP level |
| NCT05205486 | Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults | infection | Glucose, Liquid (NPC289758) | NP level |
| NCT00816478 | Effect of Oral Galactose on Focal Segmental Glomerulosclerosis (FSGS) Permeability Factor | focal segmental glomerulosclerosis | Galactose (NPC21209) | NP level |
| NCT02612259 | A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity | obesity | Tryptophan (NPC203468) | NP level |
| NCT04392362 | A Trial to Compare American Heart Association (AHA) and Simple (SIM)Method to Give Adenosine to Treat Supra-ventricular Tachycardia (SVT) | ventricular tachycardia | Adenosine (NPC156461) | NP level |
| NCT01753882 | Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI) | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
| NCT00349921 | Clonidine Versus Adenosine to Treat Neuropathic Pain | pain | Adenosine (NPC156461) | NP level |
| NCT03357666 | Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis | bacterial vaginosis | Glucose, Liquid (NPC289758) | NP level |
| NCT01307904 | The Glycemic Indices of Five Common Varieties of Dates in the Tested Among Healthy and Diabetic Subjects | diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT00243711 | A Multi-Center Randomized Study to Evaluate the Efficacy and Safety of an Investigational Lubricant Eye Drop | dry eye syndrome | Glycerin (NPC157340) | NP level |
| NCT03032965 | Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation | atrial fibrillation | Adenosine (NPC156461) | NP level |
| NCT01210183 | Biological Response of Stage IV Knee Osteoarthritis to Serial 12.5% Dextrose | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
| NCT01547364 | Caudal Epidural Injection of Dextrose For Low Back Pain | Low back pain | Glucose, Liquid (NPC289758) | NP level |
| NCT02596477 | Evaluation of Vepoloxamer in Chronic Heart Failure | heart failure | Glucose, Liquid (NPC289758) | NP level |
| NCT00617552 | Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery | ileus | Glucose, Liquid (NPC289758) | NP level |
| NCT00639808 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
| NCT01690884 | Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake | coronary artery disease | Adenosine (NPC156461) | NP level |
| NCT00619203 | Oral Glycerol and High-Dose Rectal Paracetamol to Improve the Prognosis of Childhood Bacterial Meningitis | bacterial meningitis | Glycerin (NPC157340) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
MIF,TERT,LMNA,SMN1,TRPA1,CDK2,PMP22,TDP1,ADORA1
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
MTOR
NCT02728037,NCT00298636,NCT00349921,NCT02374281,NCT00337597,NCT04791202,NCT03577730 |
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
ADORA3,MIF,TERT,LMNA,SMN1,TRPA1,CDK2,TDP1
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ADORA3,TERT,TRPA1,HTR6,TERT,TRPA1,ADORA3
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
ADORA3,TERT,LMNA,TRPA1,PMP22,ADORA2A,CYP2C19
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
GSK3B,ADORA3,ADORA2A,TERT,MTOR,CDK2
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
ADORA3
NCT01445886,NCT01022502,NCT02088281,NCT01901705,NCT00999687 |
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
MIF,TERT,TRPA1,HTR6,TDP1,ADORA1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
ADORA3,MIF,TERT,HTR6,TDP1,ADORA1
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
MAPT,TERT,LMNA,TRPA1,PMP22,ADORA1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
MAPT,TERT,ADORA1,MAPT,TERT,ADORA1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
MAPT,ADORA3,MIF,SLC25A21,TRPA1,ADORA2A
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
GSK3B,HTR6,ADORA2A,MAPT,ADORA1
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
MIF,SMN1,TRPA1,CDK2,ADORA2A
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
ADORA1,ADORA3,ADORA2A
NCT02596477 |
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
TERT,MAPT,GSK3B
NCT05297123 |
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MTOR,ADORA2A,CDK2,TERT
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
HTR6,ADORA2A
NCT01548612,NCT02067975 |
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT02910518,NCT02269735,NCT00800085,NCT04133922
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT00590070,NCT00091507,NCT02591927,NCT05424315
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
MAPT,ADORA1,ADORA2A,HTR6
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
ADORA3,SLC25A21,TERT,ADORA2A
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
SLC25A21,TERT,TRPA1,CYP2D6
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
ADORA2A,MIF,TERT,TRPA1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ADORA1,MIF,SLC25A21,TERT
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
MTOR,TERT,CDK2
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
ADORA2A,MTOR
NCT04832009 |
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
ADORA3,MTOR,TERT
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ADORA1,MAPT,HTR6
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
TERT,MTOR,ADORA2A
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ADORA1,ADORA2A,TERT
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
HTR6
NCT00686608,NCT02612259 |
Hypo-kalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C77 |
NCT00632775,NCT01251770,NCT01909336
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT00823108,NCT01485315,NCT01223690
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT04001036,NCT05185999,NCT03994471
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT01191216,NCT00567931,NCT00845689
|
Focal/segmental autonomic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D8A |
NCT00816478,NCT00816504,NCT00814255
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT01687218,NCT01575418,NCT01575405
|
GastroparesisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41.00 |
NCT00639808,NCT00612014,NCT01557296
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT01593644,NCT01690884,NCT03236311
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
ADORA3,TRPA1,ADORA2A
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
MIF,TERT,TRPA1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
LMNA,PMP22,CDK2
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
HTR6,ADORA2A,CYP2C19
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
HTR6,TERT,CYP2D6
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
HTR6,TRPA1,ADORA3
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
MTOR
NCT00003667 |
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
MIF
NCT01307904 |
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
MTOR,TERT
|
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
SMN1,SMN2
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
CYP2D6,ADORA3
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
TERT,MTOR
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
CDK2,MTOR
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
MTOR,TERT
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
MAPT,HTR6
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
ADORA2A,MAPT
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
MTOR,CDK2
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
ADORA2A,ADORA1
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ADORA2A,ADORA1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
TERT,CDK2
|
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
GSK3B,TERT
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
ADORA2A,TERT
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NCT03901144,NCT02669888
|
Hypoglycaemia without associated diabetesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A41 |
NCT02866435,NCT03241706
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT01121354,NCT05205486
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
NCT00751491,NCT01123525
|
Injury of spinal cord, level unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51.2 |
NCT01788969,NCT01753882
|
Acute ST elevation myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41.0 |
NCT00284323,NCT01747174
|
Stress-induced cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.5 |
NCT04666454,NCT02867878
|
Postoperative ileusDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA91-DB30 |
NCT02319512,NCT00617552
|
ConstipationDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME05.0 |
NCT01335386,NCT01474499
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT01223690,NCT04088591
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT01210183,NCT05160532
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT01932112,NCT03032965
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
SLC25A21,PMP22
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
TERT,TRPA1
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
ADORA2A,LMNA
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
ADORA3,LMNA
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
CDK2,ADORA3
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
MTOR
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
TERT
|
Pleural mesotheliomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26 |
MTOR
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
CDK2
|
ThymomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
CDK2
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CYP2D6
|
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
ADORA2A
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
TERT
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ADORA2A
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
ADORA2A
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
MTOR
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
MTOR
|
Unspecific substance use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4Z |
ADORA2A
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
MTOR
|
HydrocephalusDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D64 |
MTOR
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
TRPA1
|
Arteries/arterioles disorderDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD52 |
MTOR
|
Neurodegenerative disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20-8A23 |
HTR6
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
ADORA3
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ADORA3
|
ThrombocytosisDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B63 |
TERT
|
LymphangioleiomyomatosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB07 |
MTOR
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
MTOR
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
MTOR
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
ADORA2A
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
HTR6
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
MTOR
|
Dissociative neurological symptom disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B60 |
HTR6
|
Cardiac arrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC9Z |
ADORA1
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
CDK2
|
Radionuclide imagingDisease Category: NADisease ICD-11 Code: N.A. |
ADORA2A
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
ADORA2A
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
TRPA1
|
Supraventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81 |
ADORA1
|
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
GSK3B
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
TERT
|
Myotonic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71 |
GSK3B
|
Fragile X chromosomeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD55 |
GSK3B
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
MIF
|
GastroschisisDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB02 |
NCT03205553
|
Otitis mediaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA80-AB0Z |
NCT02044341
|
Ventricular tachycardiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC71.0 |
NCT04392362
|
Temporomandibular joint disordersDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0E.8 |
NCT04557878
|
Chronic lymphocytic leukaemia or small lymphocytic lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82.0 |
NCT00714103
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00565188
|
Allergic conjunctivitisDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A60.02 |
NCT00841256
|
Intracranial injury, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.Z |
NCT04677829
|
Malignant neoplasms of anus or anal canalDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C00 |
NCT00622440
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
NCT04918719
|
Other specified non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92.Y |
NCT04853082
|
Bacterial meningitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D01.0 |
NCT00619203
|
Congenital disorders of glycosylation and protein modification, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C54.Z |
NCT03404869
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB10Z |
NCT02710266
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00091507
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NCT00062972
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
NCT03860688
|
XerostomiaDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA02.1 |
NCT04392622
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT03039673
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
NCT02185729
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
NCT00179010
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT00580905
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
NCT02325583
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT02632630
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT02618824
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
NCT02678208
|
HypospadiasDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB53 |
NCT02752308
|
Skin fungal infection disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA60 |
NCT01075984
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT03690583
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
NCT00455416
|
Unstable anginaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40.0 |
NCT00091507
|
Varicose veinsDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD74-BD75 |
NCT02054325
|
Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT03024814
|
CardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43 |
NCT02681913
|
Acute promyelocytic leukaemiaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1A50 |
NCT02899169
|
Hearing disorderDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB50-AB57 |
NCT00552786
|
HyperkalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C76 |
NCT03337477
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
NCT04726436
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NCT01300260
|
Diseases of the visual system, unspecifiedDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9E1Z |
NCT00243711
|
Diseases of coronary artery, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Z |
NCT00612521
|
Lateral epicondylitis of elbowDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB55.1 |
NCT05326763
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT04588441
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
NCT03778593
|
Acute myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41 |
NCT00781404
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NCT02936830
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT00617981
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT04895358
|
Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
NCT03395288
|
Carcinoma of male breastDisease Category: X.Extension CodesDisease ICD-11 Code: XH5KW8 |
NCT01042535
|
Common cold disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SA60 |
NCT01883440
|
NeutropeniaDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B00 |
NCT00213759
|
PolyuriaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF55 |
NCT02180412
|
Low back painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84.2 |
NCT01547364
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT05029037
|
Vaginal dischargeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF3A |
NCT03357666
|
Respiratory failureDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB41 |
NCT04409665
|
Acute pancreatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC31 |
NCT02110810
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
NCT00000324
|
Diseases of the musculoskeletal system or connective tissue, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FC0Z |
NCT00835939
|
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT05014061
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ADORA2A
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
TRPA1
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
TERT
|
Intrauterine growth restrictionDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA20.1 |
ADORA2A
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ADORA2A
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
ADORA2A
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
TRPA1
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
MIF
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TERT
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
TERT
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
TERT
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
ADORA3
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
ADORA1
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
ADORA3
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
TERT
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
