Collective Molecular Activities of the Plant: Hypericum Perforatum
Plant ID: NPO4391
Plant Latin Name: Hypericum Perforatum
Taxonomy Genus: Hypericum
Taxonomy Family: Hypericaceae
Plant External Links:
NCBI TaxonomyDB:
65561
Plant-of-the-World-Online:
n.a.
Country/Region:
Turkey; Australia; Italy; Turkmenistan; South Africa; India; Lithuania; United States; Albania; Germany; Chile; Greece; Lebanon; Argentina; China; New Zealand; SpainTraditional Medicine System:
TCM; Homeopathy; SiddhaMedicinal Functions:
Analgesic; Antidepressant; Antiseptic; Antispasmodic; Aromatic; Astringent; Cholagogue; Digestive; Diuretic; Expectorant; Homeopathy; Nervine; Resolvent; Sedative; Stimulant; Vermifuge; Vulnerary
Turkey; Australia; Italy; Turkmenistan; South Africa; Lebanon; India; United States; Albania; Germany; Spain; Chile; Greece; China; Argentina; New Zealand; Lithuania
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
395 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
243 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
174 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
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