Collective Molecular Activities of the Plant: Ruta Graveolens
Plant ID: NPO3854
Plant Latin Name: Ruta Graveolens
Taxonomy Genus: Ruta
Taxonomy Family: Rutaceae
Plant External Links:
NCBI TaxonomyDB:
37565
Plant-of-the-World-Online:
n.a.
Country/Region:
Turkey; Brazil; Madagascar; Italy; Swaziland; Portugal; South Africa; Philippines; Finland; India; Zimbabwe; Algeria; Chile; Greece; Angola; Argentina; China; Spain; BulgariaTraditional Medicine System:
Indian Folk; Unani; Siddha; Ayurveda; TCM; HomeopathyMedicinal Functions:
Abortifacient; Anthelmintic; Antidiarrhoeal; Antidote; Antiinflammatory; Antispasmodic; Carminative; Emetic; Emmenagogue; Expectorant; Haemostatic; Homeopathy; Ophthalmic; Rubefacient; Stimulant; Stomachic
Brazil; Turkey; Madagascar; Angola; Portugal; Algeria; South Africa; Philippines; Finland; India; Swaziland; Zimbabwe; China; Chile; Greece; Italy; Argentina; Spain; Bulgaria
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
119 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
108 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
50 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC97541
Ingredient ID: NPC96699
Ingredient ID: NPC91620
Ingredient ID: NPC88846
Ingredient ID: NPC88445
Ingredient ID: NPC85613
Ingredient ID: NPC81016
Ingredient ID: NPC76006
Ingredient ID: NPC75881
Ingredient ID: NPC74539
Ingredient ID: NPC72627
Ingredient ID: NPC62943
Ingredient ID: NPC60720
Ingredient ID: NPC60503
Ingredient ID: NPC54416
Ingredient ID: NPC5167
Ingredient ID: NPC51146
Ingredient ID: NPC488346
Ingredient ID: NPC488345
Ingredient ID: NPC488344
Ingredient ID: NPC488343
Ingredient ID: NPC488342
Ingredient ID: NPC488341
Ingredient ID: NPC488340
Ingredient ID: NPC488339
Ingredient ID: NPC488338
Ingredient ID: NPC488337
Ingredient ID: NPC488336
Ingredient ID: NPC488335
Ingredient ID: NPC488334
Ingredient ID: NPC488333
Ingredient ID: NPC488332
Ingredient ID: NPC488331
Ingredient ID: NPC488330
Ingredient ID: NPC488329
Ingredient ID: NPC488328
Ingredient ID: NPC488327
Ingredient ID: NPC488326
Ingredient ID: NPC488325
Ingredient ID: NPC488324
Ingredient ID: NPC41499
Ingredient ID: NPC41400
Ingredient ID: NPC34770
Ingredient ID: NPC34485
Ingredient ID: NPC33320
Ingredient ID: NPC326489
Ingredient ID: NPC326093
Ingredient ID: NPC324424
Ingredient ID: NPC322498
Ingredient ID: NPC321965
Ingredient ID: NPC321166
Ingredient ID: NPC320858
Ingredient ID: NPC319343
Ingredient ID: NPC318459
Ingredient ID: NPC312146
Ingredient ID: NPC307412
Ingredient ID: NPC305648
Ingredient ID: NPC305208
Ingredient ID: NPC300299
Ingredient ID: NPC296663
Ingredient ID: NPC292370
Ingredient ID: NPC288089
Ingredient ID: NPC283810
Ingredient ID: NPC283331
Ingredient ID: NPC281931
Ingredient ID: NPC276761
Ingredient ID: NPC276207
Ingredient ID: NPC274909
Ingredient ID: NPC267801
Ingredient ID: NPC266743
Ingredient ID: NPC265547
Ingredient ID: NPC258750
Ingredient ID: NPC257188
Ingredient ID: NPC254876
Ingredient ID: NPC252256
Ingredient ID: NPC252223
Ingredient ID: NPC247553
Ingredient ID: NPC243062
Ingredient ID: NPC242517
Ingredient ID: NPC237186
Ingredient ID: NPC235682
Ingredient ID: NPC234536
Ingredient ID: NPC230199
Ingredient ID: NPC220241
Ingredient ID: NPC219564
Ingredient ID: NPC219104
Ingredient ID: NPC218109
Ingredient ID: NPC217903
Ingredient ID: NPC217829
Ingredient ID: NPC217176
Ingredient ID: NPC214309
Ingredient ID: NPC209959
Ingredient ID: NPC20082
Ingredient ID: NPC198816
Ingredient ID: NPC198160
Ingredient ID: NPC194502
Ingredient ID: NPC187058
Ingredient ID: NPC185541
Ingredient ID: NPC179605
Ingredient ID: NPC179037
Ingredient ID: NPC172784
Ingredient ID: NPC169
Ingredient ID: NPC168517
Ingredient ID: NPC16066
Ingredient ID: NPC158306
Ingredient ID: NPC153500
Ingredient ID: NPC147661
Ingredient ID: NPC144288
Ingredient ID: NPC141080
Ingredient ID: NPC141068
Ingredient ID: NPC139323
Ingredient ID: NPC131885
Ingredient ID: NPC131296
Ingredient ID: NPC12766
Ingredient ID: NPC116178
Ingredient ID: NPC110008
Ingredient ID: NPC109515
Ingredient ID: NPC103281
Ingredient ID: NPC102285
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
| Cytochrome P450 | Cytochrome P450 family 2 | CYP2A6 | Cytochrome P450 2A6 | P11509 | CHEMBL5282 |
| Cytochrome P450 | Cytochrome P450 family 2 | CYP2A13 | Cytochrome P450 2A13 | Q16696 | CHEMBL3542436 |
| Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
| Therapeutic Target | Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
| Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
| Drug Transporter | Voltage-gated sodium channel | SCN1A | Sodium channel protein type I alpha subunit | P35498 | CHEMBL1845 |
| Therapeutic Target | Voltage-gated sodium channel | SCN2A | Sodium channel protein type II alpha subunit | Q99250 | CHEMBL4187 |
| Drug Transporter | Voltage-gated sodium channel | SCN4A | Sodium channel protein type IV alpha subunit | P35499 | CHEMBL2072 |
| Therapeutic Target | Voltage-gated sodium channel | SCN5A | Sodium channel protein type V alpha subunit | Q14524 | CHEMBL1980 |
| Therapeutic Target | Voltage-gated sodium channel | SCN3A | Sodium channel protein type III alpha subunit | Q9NY46 | CHEMBL5163 |
| Drug Transporter | Voltage-gated sodium channel | SCN8A | Sodium channel protein type VIII alpha subunit | Q9UQD0 | CHEMBL5202 |
| Drug Transporter | Voltage-gated sodium channel | SCN9A | Sodium channel protein type IX alpha subunit | Q15858 | CHEMBL4296 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 20 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT00221026 | Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Crohn's Disease | Crohn's disease | Methoxsalen (NPC33320) | NP level |
| NCT03778996 | SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma | Ewing sarcoma | Methoxsalen (NPC33320) | NP level |
| NCT00054600 | Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Disease | graft versus host disease | Methoxsalen (NPC33320) | NP level |
| NCT00056056 | Ultraviolet Light Therapy Using Methoxsalen With or Without Bexarotene in Treating Patients With Mycosis Fungoides | lymphoma | Methoxsalen (NPC33320) | NP level |
| NCT00930566 | Extracorporal Photopheresis Pilot Study | lymphoid neoplasm | Methoxsalen (NPC33320) | NP level |
| NCT00030589 | Chemotherapy and Photodynamic Therapy in Treating Patients With Cutaneous T-Cell Lymphoma | lymphoma | Methoxsalen (NPC33320) | NP level |
| NCT00054613 | Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease | graft versus host disease | Methoxsalen (NPC33320) | NP level |
| NCT00221000 | Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Methoxsalen (NPC33320) | NP level |
| NCT00533195 | Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis | atopic eczema | Bergapten (NPC74539) | NP level |
| NCT00639717 | Addition of Etanercept and Extracorporeal Photopheresis (ECP) to Standard Graft-Versus-Host Disease (GVHD) Prophylaxis in Stem Cell Transplant | graft versus host disease | Methoxsalen (NPC33320) | NP level |
| NCT02524847 | Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Participants With Steroid Refractory Acute Graft Versus Host Disease | acute graft vs. host disease | Methoxsalen (NPC33320) | NP level |
| NCT03563040 | Study of Photopheresis in the Treatment of Erythrodermic MF and SS | Sezary's disease;mycosis fungoides | Methoxsalen (NPC33320) | NP level |
| NCT00056355 | Extracorporeal Photopheresis to Maintain Symptoms Remission During Steroid Withdrawal in Patients With Steroid-Dependent Crohn's Disease | Crohn's disease | Methoxsalen (NPC33320) | NP level |
| NCT03512756 | A Randomized Phase 2/3 Multi-Center Study of SM-88 in Patients With Metastatic Pancreatic Cancer | pancreatic carcinoma | Methoxsalen (NPC33320) | NP level |
| NCT04986605 | Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis | diffuse scleroderma | Methoxsalen (NPC33320) | NP level |
| NCT04291261 | Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease | acute graft vs. host disease | Methoxsalen (NPC33320) | NP level |
| NCT00005092 | Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer | leukemia;multiple myeloma;myelodysplastic syndrome | Psoralen (NPC51146) | NP level |
| NCT01686594 | PUVA Maintenance Therapy in Mycosis Fungoides | mycosis fungoides | Methoxsalen (NPC33320) | NP level |
| NCT00004359 | Phase II Pilot Study of Extracorporeal Phototherapy for Epidermolysis Bullosa Acquisita | epidermolysis bullosa acquisita | Methoxsalen (NPC33320) | NP level |
| NCT00282503 | Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease | acute graft vs. host disease | Methoxsalen (NPC33320) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
SCN4A,SCN1A,TDP1,CA9,CYP2A13,SCN9A,SCN5A,SCN8A
|
Graft-versus-host diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B24 |
NCT00282503,NCT02524847,NCT00639717,NCT00054613,NCT04291261,NCT00054600
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
TDP1,CA9,CYP2A13,CYP1A2,CA12,SCN8A
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
SCN3A,ACHE,SCN9A,SCN5A,SCN8A,SCN7A
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
SCN4A,TDP1,CA9,ACHE,CA12,TUBB6
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
SCN4A,SCN1A,CA9,CA12,CA12,CA9
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
SCN4A,CA9,ACHE,SCN5A,CA12,SCN8A
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
CA9,ACHE,SCN4A,SCN1A,CA9
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
TDP1,CA9,SCN9A,CA12,SCN8A
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
SCN1A,CYP2A6,CA9,CYP2A13,CA12
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
SCN4A,SCN1A,SCN5A,CA12
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CA9,SCN5A,CA12,SCN8A
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
SCN5A,TUBB6,ACHE,CA9
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
SCN4A,ACHE,SCN5A,CYP1A1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
CA9,ACHE,SCN9A,SCN7A
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CA9,CA12,TUBB6,SCN7A
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
SCN5A,SCN4A,SCN3A,ACHE
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
SCN5A,SCN9A,ACHE
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
CA9
NCT00056056,NCT00030589 |
Mycosis fungoidesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B01 |
CYP2A6
NCT01686594,NCT03563040 |
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
CA9,SCN5A,TUBB6
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
CA9,SCN9A,SCN8A
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
SCN1A,SCN9A,SCN8A
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CYP1A2,SCN8A,CA9
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
SCN5A,ACHE,CYP1A1
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP1A2,CA12,CYP1A1
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ACHE,SCN5A,CA12
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
CA9,SCN5A,CA12
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA12,CA9
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
SCN5A,SCN3A
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
CA9,CA12
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
SCN8A,SCN5A
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
SCN5A,CA12
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
NCT00221026,NCT00056355
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12,SCN8A
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ACHE,SCN3A
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
CA9,CYP1A1
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CA12,CA9
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
TUBB6,ACHE
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CYP1A1,CA9
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
CYP1A1,CA9
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
TUBB6,SCN3A
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE
|
Abnormal micturitionDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF50 |
SCN5A
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
ACHE
|
Genetic cardiac arrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC65 |
SCN5A
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
SCN5A
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA12
|
RadiculopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B93 |
SCN9A
|
Extremities vasodilatationDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EG00 |
SCN9A
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ACHE
|
Musculoskeletal disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FC0Z |
SCN4A
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
SCN9A
|
Ventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC71 |
SCN5A
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
CA9
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
SCN9A
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
CYP2A6
|
Trigeminal nerve disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B82 |
SCN9A
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
SCN9A
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
SCN5A
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
ACHE
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
SCN9A
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
SCN5A
|
Cardiac arrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC9Z |
SCN5A
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
ACHE
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
NCT00005092
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NCT00533195
|
Sezary syndromeDisease Category: X.Extension CodesDisease ICD-11 Code: XH8HN3 |
NCT03563040
|
LeukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2B33 |
NCT00005092
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
NCT00005092
|
Epidermolysis bullosa acquisitaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EB43 |
NCT00004359
|
Neoplasms of haematopoietic or lymphoid tissues, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B3Z |
NCT00930566
|
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT03512756
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT04986605
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NCT00221000
|
Ewing sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B52 |
NCT03778996
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
CYP1A1
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
CYP2A13
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
CYP1A1
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
SCN3A
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ACHE
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CA12
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
SCN1A
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
SCN3A
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
