CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Cyclea Barbata

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TCGATGCCTGCAGAACGACCCGCGAACCATTGACAACGAGAATTGAGCGACGAGGAGGGCCGATCAGCCCCCGTCGTCGAGCAACAAAACCCCGGCGCGGCACGCGCCAAGGAAATTTTAAATCGAAACGGGGGAGACCACGCGTCGGGGCGGCTGGCCCGCACGGCGACGTTGCGCTCCCGATAACCTTAACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCGAGTCCATTTTTGGTCGAGGGCACGTCTGCCTGGGCGTCTCGTGACGCACCACAACCCGCCCGCTGCGGGGAGTGGAGATTGGCCTTCCCGCGCGACGAGCACGGTTGGCTCAAATAGCAGCCTCGACGCTCGGACGACGCGATCAGCGGTGGTTGATGAGAGAATCCTTGTCAAGCGAGTGACGCGGTCGGACCGGCGCGATCCGGGGGGAGCACCCTATTCGCATATACCTT

Click for details-----ITS1

TCGATGCCTGCAGAACGACCCGCGAACCATTGACAACGAGAATTGAGCGACGAGGAGGGCCGATCAGCCCCCGTCGTCGAGCAACAAAACCCCGGCGCGGCACGCGCCAAGGAAATTTTAAATCGAAACGGGGGAGACCACGCGTCGGGGCGGCTGGCCCGCACGGCGACGTTGCGCTCCCGATAACCTTAA

Click for details-----ITS2

GACGCACCACAACCCGCCCGCTGCGGGGAGTGGAGATTGGCCTTCCCGCGCGACGAGCACGGTTGGCTCAAATAGCAGCCTCGACGCTCGGACGACGCGATCAGCGGTGGTTGATGAGAGAATCCTTGTCAAGCGAGTGACGCGGTCGGACCGGCGCGATCCGGGGGGAGCACCCTATTCGCATATACCTT

Taxonomic Information

Plant ID: NPO3849
Plant Latin Name: Cyclea Barbata
Taxonomy Genus: Cyclea
Taxonomy Family: Menispermaceae

Plant External Links:

NCBI TaxonomyDB: 152373
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:

Thailand; Indonesia; China; Vietnam

Traditional Medicine System:

TCM

Geographical Distribution

Thailand; Indonesia; China; Vietnam

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

24 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

9 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)