CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Orixa Japonica

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TCGAACCCTGCCTAGCAGAACGACCCGCGAACTCGTTAAAATCACTGGCGGGGGGAGAGCCCCTCGGGCGCTCCCCCCCCTATCGCCGCGGGTGCGGGACTCGTCCCGCTCCCCGTGGTGAAACAACGAACCCCCGGCGCGGACTGCGCCAAGGAAATCTAACGAGAGAGCACGCGCTCGGGGCCCCGGTCACGGTGTGCCCCCGGGATGCGGCGCCTTCTTTCAATTTATCTATAACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCCAAGCCTTTAGGCCGAGGGCACGTCTGCCTGGGTGTCACGCATCGTTGCCCCACCCCACCCCCTTGGGGACCTGGCGGTGCGGGCGGAAAATGGCCTCCCGTGTGCTCCCCGCCCGCGGTTGGCCTAAATCTGAGTCCTCGGCGACCGAAGCCGCGACGATCGGTGGTGAAAACAAGCCTCTCGAGCTTCACGTCGCGTGCACGCGTCTCCGAACGAGGCCTCGTGGACCCTTACGCTCCGCGCAAGCGGCGCTCGCATC

Click for details-----ITS1

TCGAACCCTGCCTAGCAGAACGACCCGCGAACTCGTTAAAATCACCGGCGGGGGGAGCGCCCCACGGGCTCTCCTCCCCCTCTCGCCGCGGGTGCGGGACTCGTCCCGCTCCCCGCGGCGAAACAACGAACCCCCGGCGCGGACTGTGCCAAGGAAATCTAACGAGAGAGCACGCTCTCGGGGCCCCGGACACGGTGTGCCCCCGGGATGCAGCGCCTTCTTTCAATTTATCTATAA

Click for details-----ITS2

ATCGTTGCCCCACCCCACCCCCTTGGGGACCTGGCGGTGCGGGCGGAAAATGGCCTCCCGTGTGCTCCCCGCCCGCGGTTGGCCTAAATCTGAGTCCTCGGCGACCGAAGCCGCGACGATCGGTGGTGAAAACAAGCCTCTCGAGCTTCACGTCGCGTGCACGCGTCTCCGAACGAGGCCTCGTGGACCCTTACGCTCCGCGCAAGCGGCGCTCGCATC

Taxonomic Information

Plant ID: NPO340
Plant Latin Name: Orixa Japonica
Taxonomy Genus: Orixa
Taxonomy Family: Rutaceae

Plant External Links:

NCBI TaxonomyDB: 354507
Plant-of-the-World-Online: 162301-1

Used in Medicines

Country/Region:

China

Traditional Medicine System:

TCM

Medicinal Functions:

Febrifuge

Geographical Distribution

China; South Africa

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

36 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

35 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)