CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Crescentia Cujete

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PLANiTS DNA barcode

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Taxonomic Information

Plant ID: NPO29177
Plant Latin Name: Crescentia Cujete
Taxonomy Genus: Crescentia
Taxonomy Family: Bignoniaceae

Plant External Links:

NCBI TaxonomyDB: 1125401
Plant-of-the-World-Online: 319161-2

Used in Medicines

Country/Region:

Brazil; Netherlands; India; Vietnam; China; Thailand

Traditional Medicine System:

Indian Folk; TCM; Siddha

Geographical Distribution

Brazil; Costa Rica; Bahamas; Peru; Venezuela; Ecuador; Benin; Cuba; El Salvador; Guatemala; China; Thailand; Dominican Republic; Belize; Netherlands; Gambia; Trinidad and Tobago; Vietnam; Haiti; Jamaica; Honduras; Chad; Mexico; India; Colombia; Nicaragua

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

16 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

11 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)