CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Caragana Sinica

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TCGATGCCTTACATGCAGACCGACCTGTGAACCTGTTTGAACACGTAGGGTTGGCTTGAGGTGTTCCACGCCTCGGCCTCCCTTTGAGGTAGGAGGGGGCCACCAGTGCGTTTCCCTGCTGCCGAAACACAAACCCCGGCGCTGAATGCGCCAAGGAACTGTATTTYGTTCAGTGCGCCCCCGTTGGCCCGGAGACGGTGTYCTTGCGGGTGTTGTTTTGAAGCATGACGCATAATGACTCTCGGCAACGAATATCTAGGCTCTTGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCGAAGCCATTAGGTTGAGGGCACGTCTGCCTGGGCGTCACATATCGTTGCCCGAAGCCAATTTCCTCCTGATGGGAGGTATGTTGTGCAGGGTGAATGATGGCTTCCCGTGAGCAATGCTGCCTCATGGTTGGTTGAAAATTGAGTCCTTGGTAGGGTGTGCCATGATAGATGGTGGTTGAGTGATGCACGAGACCATATCATGTGAGACTCTACCAAACTTGGCCTCTATGACCCACGTGCGTCTTTGAACGCTCATGAC

Click for details-----ITS1

Click for details-----ITS2

Taxonomic Information

Plant ID: NPO28914
Plant Latin Name: Caragana Sinica
Taxonomy Genus: Caragana
Taxonomy Family: Fabaceae

Plant External Links:

NCBI TaxonomyDB: 403832
Plant-of-the-World-Online: 483896-1

Used in Medicines

Country/Region:

South Korea; China

Traditional Medicine System:

TCM

Medicinal Functions:

Antiinflammatory; Restorative; Tonic; VD

Geographical Distribution

Japan; South Korea; China; South Africa

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

53 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

19 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)