CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Piper Betle

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TTGATATGCCCATCGTAACAAGACAGACGGAAGCGAACTTGTGAACCCTCGTGTTCTTGGCCCGAACGCCGGGGCGGCGCTCTGCACGTGTCGGGCAACGACGAACCAAATCTCGGCGCAGGACGCGCCAAGCAACTCGGGAAGCTTTGGTTGCGGCATCCTCTTCCCTGTCGGGCTGGAGGGCGCGCGTCGAACACTTACCTACAAGTCAGTACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCGAGGCCTTTCGGCCGAGGGCACATCTGCTTGGGCGTTAAACAACTCGTCTCCCGCCGCCTTCCCCCCTGCAGACTCCGAGCGAGGGGCCTGTCGGAGATGAGGGTAGGCTGGGCGGAGTCTGGCCGTCCGTGTGCCTGCAGCGCATGCGGTTGGCTGAAAAGCCCGGGCCATGGGCTGCGTGCGCGGCTCAACGAGTGGTGGTTGTGCGCTCGCAAGGCCGCGATTGTCAGCACGTTGCGCCATTCGCTTCTCGATTGCCCGGCAAGTACCCAACGCGATCGAAACGTCCAATCCACGGATCGATTCGAA

Click for details-----ITS1

TTGATATATGCCCATCGTAACAAGACAGACGGAAGCGAACTTGTGAACCCTCGTGTTCCTGGCCCGAACGCCGGGGCGACGCTCTGCACGTGTCGGGCAACGACGAACCAAATCTCGGCGCAGGACGCGCCAAGCAACTCGGGAAGCTTTGATTGCGGCATCCTCTTCCCTGTCGGGCTGGAGGGCGCGCGTCGAACACTTACTTACAAGTCAGTA

Click for details-----ITS2

AACTCGTCTCCCGCCGCCCTCTCCCTCCAGACTCCGATCGAGGAGTCTGCCCGAGGCGAGGGTAGGTCGGGGCGGARTCTGGTCGTCCGTGTGCCCGCAGAGCGCACGCGGTTGGGTGAAAAGCCCGGGCCACGGGCCGAGTGCGGCTCAACGGGTGGTGGTTGTGCGCCCTCTCTTTCGAGCGGGGCCGCGATTGTCAGCACGCTGCGCCGTTCGCTTCTCGATTGCCCGGCAAGTACCCAACGCGATCGAAACGTCCAATCGGCGGCTCGATTCGAATTGCG

Taxonomic Information

Plant ID: NPO26872
Plant Latin Name: Piper Betle
Taxonomy Genus: Piper
Taxonomy Family: Piperaceae

Plant External Links:

NCBI TaxonomyDB: 13217
Plant-of-the-World-Online: 680605-1

Used in Medicines

Country/Region:

Madagascar; Angola; South Africa; Indonesia; India; Zimbabwe; China; Swaziland; Thailand

Traditional Medicine System:

Sowa-Rigpa; Indian Folk; Unani; Siddha; Ayurveda; TCM

Geographical Distribution

Madagascar; Bangladesh; Cambodia; Swaziland; Laos; Australia; Cuba; Papua New Guinea; Zimbabwe; China; Thailand; Maldives; Philippines; Indonesia; Mauritius; Trinidad and Tobago; Vietnam; Angola; Myanmar; South Africa; India; Sri Lanka; Fiji

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

55 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

48 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)