Collective Molecular Activities of the Plant: Fagopyrum Esculentum
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PLANiTS DNA barcode
Taxonomic Information
Plant ID: NPO26343
Plant Latin Name: Fagopyrum Esculentum
Taxonomy Genus: Fagopyrum
Taxonomy Family: Polygonaceae
Plant External Links:
NCBI TaxonomyDB:
3617
Plant-of-the-World-Online:
n.a.
Used in Medicines
Country/Region:
Madagascar; Angola; South Africa; Tanzania; India; Zimbabwe; Rwanda; Swaziland; Kenya; Thailand; South Korea; ChinaTraditional Medicine System:
Indian Folk; TCM; HomeopathyMedicinal Functions:
Acrid; Astringent; Galactogogue; Vasodilator
Geographical Distribution
Madagascar; Angola; South Africa; Tanzania; India; Zimbabwe; Rwanda; China; Swaziland; Thailand; Kenya; South Korea
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Compounds Summary
Overview of Ingredients
139 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
90 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
72 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC98163
Ingredient ID: NPC94167
Ingredient ID: NPC93888
Ingredient ID: NPC91495
Ingredient ID: NPC8747
Ingredient ID: NPC85813
Ingredient ID: NPC81340
Ingredient ID: NPC81010
Ingredient ID: NPC66352
Ingredient ID: NPC62469
Ingredient ID: NPC62045
Ingredient ID: NPC61066
Ingredient ID: NPC60175
Ingredient ID: NPC60151
Ingredient ID: NPC59650
Ingredient ID: NPC55412
Ingredient ID: NPC49103
Ingredient ID: NPC490427
Ingredient ID: NPC490424
Ingredient ID: NPC490321
Ingredient ID: NPC490288
Ingredient ID: NPC489907
Ingredient ID: NPC489877
Ingredient ID: NPC48623
Ingredient ID: NPC38779
Ingredient ID: NPC37819
Ingredient ID: NPC36999
Ingredient ID: NPC328740
Ingredient ID: NPC328447
Ingredient ID: NPC317120
Ingredient ID: NPC315669
Ingredient ID: NPC313955
Ingredient ID: NPC309697
Ingredient ID: NPC301696
Ingredient ID: NPC301583
Ingredient ID: NPC299625
Ingredient ID: NPC29601
Ingredient ID: NPC295644
Ingredient ID: NPC294548
Ingredient ID: NPC290319
Ingredient ID: NPC288840
Ingredient ID: NPC285322
Ingredient ID: NPC282031
Ingredient ID: NPC281686
Ingredient ID: NPC279026
Ingredient ID: NPC278976
Ingredient ID: NPC278010
Ingredient ID: NPC27633
Ingredient ID: NPC275463
Ingredient ID: NPC272614
Ingredient ID: NPC272343
Ingredient ID: NPC269980
Ingredient ID: NPC269919
Ingredient ID: NPC265305
Ingredient ID: NPC264493
Ingredient ID: NPC261831
Ingredient ID: NPC254848
Ingredient ID: NPC254474
Ingredient ID: NPC253509
Ingredient ID: NPC248955
Ingredient ID: NPC242580
Ingredient ID: NPC23962
Ingredient ID: NPC237812
Ingredient ID: NPC230301
Ingredient ID: NPC228978
Ingredient ID: NPC226453
Ingredient ID: NPC226027
Ingredient ID: NPC225098
Ingredient ID: NPC224259
Ingredient ID: NPC223695
Ingredient ID: NPC219143
Ingredient ID: NPC218109
Ingredient ID: NPC216714
Ingredient ID: NPC214502
Ingredient ID: NPC213876
Ingredient ID: NPC209971
Ingredient ID: NPC209054
Ingredient ID: NPC208793
Ingredient ID: NPC208450
Ingredient ID: NPC20791
Ingredient ID: NPC203468
Ingredient ID: NPC201844
Ingredient ID: NPC20045
Ingredient ID: NPC199072
Ingredient ID: NPC192402
Ingredient ID: NPC189436
Ingredient ID: NPC188563
Ingredient ID: NPC188428
Ingredient ID: NPC185755
Ingredient ID: NPC17810
Ingredient ID: NPC1769
Ingredient ID: NPC176740
Ingredient ID: NPC174246
Ingredient ID: NPC171188
Ingredient ID: NPC168326
Ingredient ID: NPC1682
Ingredient ID: NPC167400
Ingredient ID: NPC167072
Ingredient ID: NPC165967
Ingredient ID: NPC162742
Ingredient ID: NPC162547
Ingredient ID: NPC158306
Ingredient ID: NPC158079
Ingredient ID: NPC157410
Ingredient ID: NPC156655
Ingredient ID: NPC155185
Ingredient ID: NPC152451
Ingredient ID: NPC150950
Ingredient ID: NPC1507
Ingredient ID: NPC147983
Ingredient ID: NPC142753
Ingredient ID: NPC142000
Ingredient ID: NPC141765
Ingredient ID: NPC140310
Ingredient ID: NPC139891
Ingredient ID: NPC139493
Ingredient ID: NPC137958
Ingredient ID: NPC136014
Ingredient ID: NPC134616
Ingredient ID: NPC133746
Ingredient ID: NPC130683
Ingredient ID: NPC13059
Ingredient ID: NPC126681
Ingredient ID: NPC126409
Ingredient ID: NPC124436
Ingredient ID: NPC120649
Ingredient ID: NPC117238
Ingredient ID: NPC116622
Ingredient ID: NPC11609
Ingredient ID: NPC11433
Ingredient ID: NPC113733
Ingredient ID: NPC113212
Ingredient ID: NPC112890
Ingredient ID: NPC111897
Ingredient ID: NPC110899
Ingredient ID: NPC108779
Ingredient ID: NPC10781
Ingredient ID: NPC106547
Ingredient ID: NPC1042
Classification of Human Proteins Collectively Targeted by the Plant
*The classification criteria of Drug Transporter (DTP), CYP450 are referred to DrugMap. Other molecular targets in CMAUP are classified as therapeutic targets.
.
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
| Therapeutic Target | Enzyme | ALOX12 | Arachidonate 12-lipoxygenase | P18054 | CHEMBL3687 |
| Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
| Therapeutic Target | Enzyme | NOX4 | NADPH oxidase 4 | Q9NPH5 | CHEMBL1250375 |
| Therapeutic Target | Enzyme | AKR1C3 | Aldo-keto-reductase family 1 member C3 | P42330 | CHEMBL4681 |
| Therapeutic Target | Fatty acid binding protein family | FABP5 | Fatty acid binding protein epidermal | Q01469 | CHEMBL3674 |
| Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK3 | Glutamate receptor ionotropic kainate 3 | Q13003 | CHEMBL3684 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIA4 | Glutamate receptor ionotropic, AMPA 4 | P48058 | CHEMBL3190 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK5 | Glutamate receptor ionotropic kainate 5 | Q16478 | CHEMBL2675 |
| Therapeutic Target | Ionotropic glutamate receptor | GRIK1 | Glutamate receptor ionotropic kainate 1 | P39086 | CHEMBL1918 |
| Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
| Therapeutic Target | Lyase | CA14 | Carbonic anhydrase XIV | Q9ULX7 | CHEMBL3510 |
| Therapeutic Target | Membrane receptor | APP | Beta amyloid A4 protein | P05067 | CHEMBL2487 |
| Therapeutic Target | Nuclear hormone receptor subfamily 1 | PPARA | Peroxisome proliferator-activated receptor alpha | Q07869 | CHEMBL239 |
| Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
| Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
| Therapeutic Target | Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
| Therapeutic Target | Peptide receptor (family A GPCR) | TSHR | Thyroid stimulating hormone receptor | P16473 | CHEMBL1963 |
| Therapeutic Target | Protein Kinase | KDR | Vascular endothelial growth factor receptor 2 | P35968 | CHEMBL279 |
| Therapeutic Target | Protein Kinase | IGF1R | Insulin-like growth factor I receptor | P08069 | CHEMBL1957 |
| Therapeutic Target | Protein Kinase | PIM1 | Serine/threonine-protein kinase PIM1 | P11309 | CHEMBL2147 |
| Therapeutic Target | Protein Kinase | CDK1 | Cyclin-dependent kinase 1 | P06493 | CHEMBL308 |
| Therapeutic Target | Protein Kinase | MAPK1 | MAP kinase ERK2 | P28482 | CHEMBL4040 |
| Therapeutic Target | Protein Kinase | FLT3 | Tyrosine-protein kinase receptor FLT3 | P36888 | CHEMBL1974 |
| Therapeutic Target | Protein Kinase | YES1 | Tyrosine-protein kinase YES | P07947 | CHEMBL2073 |
| Therapeutic Target | Protein Kinase | AURKB | Serine/threonine-protein kinase Aurora-B | Q96GD4 | CHEMBL2185 |
| Therapeutic Target | Protein Kinase | AXL | Tyrosine-protein kinase receptor UFO | P30530 | CHEMBL4895 |
| Therapeutic Target | Protein Kinase | MET | Hepatocyte growth factor receptor | P08581 | CHEMBL3717 |
| Drug Transporter | SLC superfamily of solute carriers | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Q9Y6L6 | CHEMBL1697668 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | HCAR2 | Hydroxycarboxylic acid receptor 2 | Q8TDS4 | CHEMBL3785 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR4 | G-protein coupled receptor 120 | Q5NUL3 | CHEMBL5339 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR1 | Free fatty acid receptor 1 | O14842 | CHEMBL4422 |
| Therapeutic Target | Small molecule receptor (family C GPCR) | GRM8 | Metabotropic glutamate receptor 8 | O00222 | CHEMBL3228 |
| Therapeutic Target | Small molecule receptor (family C GPCR) | GRM1 | Metabotropic glutamate receptor 1 | Q13255 | CHEMBL3772 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
| Therapeutic Target | Transferase | GSTP1 | Glutathione S-transferase Pi | P09211 | CHEMBL3902 |
| Therapeutic Target | Unclassified protein | SNCA | Alpha-synuclein | P37840 | CHEMBL6152 |
Clinical Trials Summary
Overview
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 439 | |
 Plant level | 1 | |
Clinical trial details
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT01083329 | Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects | obesity | Niacin (NPC167400) | NP level |
| NCT01348204 | Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators | cystic fibrosis | Quercetin (NPC20791) | NP level |
| NCT00111891 | An Investigational Drug Study Evaluating a Novel Approach to Treat Dyslipidemia (0524A-032) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00520247 | Effect of Enalapril Plus Folic Acid on Blood Pressure and Glycometabolism | hypertension | Folic Acid (NPC147983) | NP level |
| NCT00170404 | TB Nutrition, Immunology and Epidemiology | tuberculosis | Retinol (NPC55412);Niacin (NPC167400);Folic Acid (NPC147983) | NP level |
| NCT00220532 | Folate and Protection Against Cervical Cancer | cervical cancer | Folic Acid (NPC147983) | NP level |
| NCT02825901 | Efficacy Testing of Djulis-Buckwheat Drink on Cardiovascular Protection | Prehypertension|Hypertension Stage 1 | Fagopyrum Esculentum | Plant level As single plant |
| NCT00533611 | Effect of MK0524A on Flushing Caused by Niacin (0524A-056) | Flushing | Niacin (NPC167400) | NP level |
| NCT00949104 | Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preterm Neonates | pain | Sucrose (NPC130683) | NP level |
| NCT02786823 | Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes | type 2 diabetes mellitus | Folic Acid (NPC147983) | NP level |
| NCT00452829 | Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study) | neural tube defect | Folic Acid (NPC147983) | NP level |
| NCT04750902 | A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children | dental caries | Arginine (NPC226453) | NP level |
| NCT04630964 | The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT03956056 | Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy | pancreatic carcinoma | Lysine (NPC112890) | NP level |
| NCT00299104 | A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00384293 | Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02589145 | Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT01931787 | CPI-613 in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer | small cell lung carcinoma | Octanoic Acid (NPC301696) | NP level |
| NCT02908581 | Effect of Iron and Folic Acid on Skin Fungal Pattern in Patients With Arsenicosis | heavy metal poisoning | Folic Acid (NPC147983) | NP level |
| NCT02086864 | A Placebo Controlled Study of Homeopathic Treatment of Children and Youth With ADHD | attention deficit hyperactivity disorder | Sucrose (NPC130683) | NP level |
| NCT00000372 | Glycine and D-Cycloserine in Schizophrenia | schizophrenia | Glycine (NPC126681) | NP level |
| NCT01057589 | A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer | upper aerodigestive tract neoplasm | Folic Acid (NPC147983) | NP level |
| NCT00150722 | High-Density Lipoprotein (HDL) Modulation and Endothelial Function | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT00345605 | Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder | argininosuccinic aciduria | Arginine (NPC226453) | NP level |
| NCT03493178 | Glutathione in Mild Cognitive Impairment | Cognitive impairment | Glycine (NPC126681) | NP level |
| NCT01356966 | Exercise Intolerance in Renal Failure | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT02061449 | Poly ICLC, Radiation, and Romidepsin for Advanced Cutaneous T Cell Lymphoma | Cutaneous T-cell lymphoma | Lysine (NPC112890) | NP level |
| NCT00855257 | Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome | acute coronary syndrome | Niacin (NPC167400) | NP level |
| NCT03478878 | Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation | age-related macular degeneration | Vitamin A Palmitate (NPC228978) | NP level |
| NCT01501942 | Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic Asthma | asthma | Glycine (NPC126681) | NP level |
| NCT00291226 | Glycine vs Placebo for the Schizophrenia Prodrome | schizophrenia | Glycine (NPC126681) | NP level |
| NCT02541045 | Clinical Trial to Evaluate the Efficacy of Metadoxine as a Therapy for Patients With Non-alcoholic Steatohepatitis | non-alcoholic fatty liver disease | Pyridoxine (NPC269919) | NP level |
| NCT04201873 | Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma | glioblastoma multiforme | Lysine (NPC112890) | NP level |
| NCT02990364 | Combination Analgesia for Neonatal Circumcision | pain | Sucrose (NPC130683) | NP level |
| NCT01191216 | 1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT00513617 | Effectiveness of Arginine as a Treatment for Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT02066688 | Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer | colorectal neoplasm | Folic Acid (NPC147983) | NP level |
| NCT00127218 | High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT03082001 | Sucrose to Reduce Pain During Initiation of Venipuncture in Extremely Low Birth Weight Babies | pain | Sucrose (NPC130683) | NP level |
| NCT02427581 | Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy | triple-negative breast cancer | Lysine (NPC112890) | NP level |
| NCT00376584 | Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED) | Disorder of lipid metabolism;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT01388764 | Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT04535427 | Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Arginine (NPC226453) | NP level |
| NCT00006136 | Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia | Beta-thalassemia | Arginine (NPC226453) | NP level |
| NCT00147368 | Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT03062449 | Phase IIa L-serine Trial for eAD | Alzheimer disease | Serine (NPC219143) | NP level |
| NCT03266965 | Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach | multiple sclerosis | Histidine (NPC237812) | NP level |
| NCT04337879 | A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer | colorectal cancer | Folic Acid (NPC147983) | NP level |
| NCT03333278 | The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial | Sepsis;septic shock | Thiamine (NPC150950) | NP level |
| NCT05289908 | Intrathecal Pemetrexed for Leptomeningeal Metastasis | leptomeningeal metastasis | Folic Acid (NPC147983) | NP level |
| NCT00903617 | Study to Test GSK256073 in Patients With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT05470998 | L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT01842139 | Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission | acute myeloid leukemia | Lysine (NPC112890) | NP level |
| NCT03989271 | Biological Effects of Quercetin in COPD | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT04999137 | Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa | Sepsis;septic shock | Thiamine Hydrochloride (NPC189436) | NP level |
| NCT00652431 | Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00218946 | Nasogastric Tube in Premature Babies - Pain and Treatment | premature birth | Sucrose (NPC130683) | NP level |
| NCT01603446 | L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome | MELAS | Arginine (NPC226453) | NP level |
| NCT01828437 | Addition of Pyridoxine to Prednisolone in Infantile Spasms | West syndrome | Pyridoxine (NPC269919) | NP level |
| NCT00000512 | Familial Atherosclerosis Treatment Study | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00500045 | Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT00269217 | Lipid Efficacy Study (0524B-022)(COMPLETED) | Combined hyperlipidemia;Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00133562 | HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition | malnutrition | Glycine (NPC126681) | NP level |
| NCT03418935 | Remaxol® in Mechanical Jaundice of Non-malignant Origin | obstructive jaundice | Methionine (NPC152451) | NP level |
| NCT00848172 | Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor | essential tremor | Octanoic Acid (NPC301696) | NP level |
| NCT02848131 | Senescence in Chronic Kidney Disease | chronic kidney disease | Quercetin (NPC20791) | NP level |
| NCT00070434 | S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum | colorectal carcinoma | Pyridoxine (NPC269919) | NP level |
| NCT00609518 | A Study for Patients With Non-Squamous Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT02075970 | Optimized Erythropoietin (EPO) Treatment | neonatal anemia | Biotin (NPC199072) | NP level |
| NCT01233492 | Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme | Central Nervous System Neoplasm | L-Phenylalanine (NPC10781) | NP level |
| NCT03088345 | Early Use of Vasopressin in Post-Fontan Management | congenital heart disease | Arginine (NPC226453) | NP level |
| NCT01190995 | Role of Repeated Painful Procedures in Preterm Neonates on Short Term Neurobehavioural Outcome | pain | Sucrose (NPC130683) | NP level |
| NCT00493064 | To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT00694564 | Evaluation of S-adenosyl Methionine (SAM-e) for Recurrent Abdominal Pain in Children | Abdominal pain | Methionine (NPC152451) | NP level |
| NCT03359239 | Atezolizumab Given in Combination With a Personalized Vaccine in Patients With Urothelial Cancer | urinary bladder cancer | Lysine (NPC112890) | NP level |
| NCT00406874 | Effect of Omega 3 Fats on Sperm Quality and Sexual Function | infertility | Folic Acid (NPC147983) | NP level |
| NCT01985685 | The Effect of Thiamine vs. Placebo on VO2 in Critical Illness | respiratory failure | Thiamine (NPC150950) | NP level |
| NCT02067975 | Tryptophan MRI in People With Schizophrenia and Healthy Controls | schizophrenia | Tryptophan (NPC203468) | NP level |
| NCT01720147 | Quercetin in Children With Fanconi Anemia; a Pilot Study | Fanconi anemia | Quercetin (NPC20791) | NP level |
| NCT00986609 | MUC1 Vaccine for Triple-negative Breast Cancer | inflammatory breast carcinoma;triple-negative breast cancer | Lysine (NPC112890) | NP level |
| NCT02730949 | D-chiro-Inositol in Overweight Type 1 Diabetes Patients | type 1 diabetes mellitus | Folic Acid (NPC147983) | NP level |
| NCT02018965 | Niacin on Immune Activation : a Proof-of-concept Study | HIV infection | Niacin (NPC167400) | NP level |
| NCT01902381 | CPI-613 in Treating Patients With Myelodysplastic Syndromes Who Failed Previous Therapy | myelodysplastic syndrome | Octanoic Acid (NPC301696) | NP level |
| NCT01010581 | SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02929888 | Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate in STEMI Patients | acute myocardial infarction | Lysine (NPC112890) | NP level |
| NCT00567931 | 1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery | neoplasm | Tryptophan (NPC203468) | NP level |
| NCT00950989 | Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03478865 | Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark Adaptation | age-related macular degeneration | Vitamin A Palmitate (NPC228978) | NP level |
| NCT02226484 | Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? | gastroesophageal reflux disease | Quercetin (NPC20791) | NP level |
| NCT01783431 | Study of Vaccination With Poly-ICLC and Peptide-pulsed Dendritic Cells | melanoma | Lysine (NPC112890) | NP level |
| NCT01733407 | L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1 | hereditary sensory and autonomic neuropathy type 1 | Serine (NPC219143) | NP level |
| NCT03866174 | A Study of Psilocybin for Major Depressive Disorder (MDD) | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT01031927 | N-methyl Glycine (Sarcosine) for the Treatment of Obsessive Compulsive Disorder (OCD) | obsessive-compulsive disorder | Glycine (NPC126681) | NP level |
| NCT02388178 | To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Study | dental caries | Arginine (NPC226453) | NP level |
| NCT00033722 | Lometrexol Plus Folic Acid in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer | lung cancer | Folic Acid (NPC147983) | NP level |
| NCT00204932 | Effects of CLA Supplements on Body Weight and Fat Oxidation | obesity | Linoleic Acid (NPC85813) | NP level |
| NCT01005303 | Micronutrient Supplementation in Patients With Heart Failure | heart failure | Folic Acid (NPC147983);Pyridoxine (NPC269919);Niacin (NPC167400);Retinol (NPC55412);Biotin (NPC199072) | NP level |
| NCT00056433 | Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT01953536 | Safety and Efficacy Study of Vintafolide and Vintafolide Plus Paclitaxel Compared to Paclitaxel Alone in Participants With Triple Negative Breast Cancer (TNBC) (MK-8109-004) | breast neoplasm | Folic Acid (NPC147983) | NP level |
| NCT00402883 | Chemotherapy, Radiotherapy and Bevacizumab in Patients With Unresectable Stage III Non-Small-Cell Lung Cancer | lung cancer | Folic Acid (NPC147983) | NP level |
| NCT01583647 | A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00034463 | ALIMTA (Pemetrexed) in Patients With Locally Advanced or Metastatic Cancer | cancer | Folic Acid (NPC147983) | NP level |
| NCT01864057 | Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants | beriberi | Thiamine Hydrochloride (NPC189436) | NP level |
| NCT00441870 | Study of EC0225 for the Treatment of Refractory or Metastatic Tumors | cancer | Folic Acid (NPC147983) | NP level |
| NCT01375101 | Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus | oral lichen planus | Quercetin (NPC20791) | NP level |
| NCT00482560 | Analgesic Effect of Breast Feeding vs Sucrose in Neonatal Screening | pain | Sucrose (NPC130683) | NP level |
| NCT00269204 | Lipid Efficacy/Tolerability Study (0524A-020) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00096330 | Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00965653 | A Study of Subcutaneously Administered Tocilizumab in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00215878 | D-serine for Posttraumatic Stress Disorder Treatment | post-traumatic stress disorder | Serine (NPC219143) | NP level |
| NCT01720316 | Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders | bipolar disorder | Glycine (NPC126681) | NP level |
| NCT03685773 | The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT01785186 | Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT00953134 | Periconceptional Iron Supplementation in Rural Bangladesh | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT01188876 | Carboplatin/Pralatrexate in Recurrent Platinum-Sensitive Ovarian, Fallopian or Primary Peritoneal Cancer | fallopian tube cancer;ovarian cancer;peritoneum cancer | Folic Acid (NPC147983) | NP level |
| NCT00062556 | Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT01949116 | Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV Medications | HIV infection | Folic Acid (NPC147983) | NP level |
| NCT02013362 | Phase I/II Clinical Study of Pralatrexate in Japanese Patients With Relapsed or Refractory Peripheral T-cell Lymphoma | unspecified peripheral T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT05281926 | A Phase I, Open-label Study to Assess the Safety and Efficacy of Poly-ICLC Plus Nivolumab in Unresectable Hepatocellular Carcinoma Patients | hepatocellular carcinoma | Lysine (NPC112890) | NP level |
| NCT05422885 | Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease | aging | Quercetin (NPC20791) | NP level |
| NCT03166254 | Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung Cancer | non-small cell lung carcinoma | Lysine (NPC112890) | NP level |
| NCT00536510 | Effect of MK0524A on Cholesterol Levels (0524A-048) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT02541708 | IV Ferric Carboxymaltose Compared With Oral Iron in the Treatment of Iron Deficiency Anemia at Delivery in Tanzania | Iron deficiency anemia | Folic Acid (NPC147983) | NP level |
| NCT00396500 | Deworming and Vitamin A (DEVTA) Prepilot Study | malnutrition;parasitic infection | Retinol (NPC55412) | NP level |
| NCT00446147 | Study of Pyridoxine for Hand-Foot Syndrome | Hand-foot syndrome | Pyridoxine (NPC269919) | NP level |
| NCT00961636 | A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00405665 | The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis | cystic fibrosis | Arginine (NPC226453) | NP level |
| NCT00120822 | Folic Acid Supplementation in Gambian Primigravidae | malaria | Folic Acid (NPC147983) | NP level |
| NCT05210504 | Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3 | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
| NCT00082251 | Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT01071525 | The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02174705 | Rotavirus vs. Sucrose for Vaccine Injection Pain | pain | Sucrose (NPC130683) | NP level |
| NCT00861523 | Does Thiamine Help Vomiting and Nausea in Pregnancy? | hyperemesis gravidarum | Thiamine (NPC150950);Thiamine Hydrochloride (NPC189436) | NP level |
| NCT00098319 | Oral Cleft Prevention Trial in Brazil | cleft lip;Cleft palate | Folic Acid (NPC147983) | NP level |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00998946 | Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma | lymphoma | Folic Acid (NPC147983) | NP level |
| NCT03387046 | A Pilot Study in Participants With Relapsing Remitting Multiple Sclerosis (RR-MS) | relapsing-remitting multiple sclerosis | D-Aspartate (NPC285322) | NP level |
| NCT00000324 | Tryptophan and Behavior Therapy for Cocaine Abuse - 1 | cocaine dependence | Tryptophan (NPC203468) | NP level |
| NCT00136188 | Nitric Oxide (NO) Activity and Diabetic Nephropathy | diabetic nephropathy | Folic Acid (NPC147983) | NP level |
| NCT00606502 | Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00769132 | A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00080275 | Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT03510715 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00796887 | Randomized, Controlled Trial of Extended-Release Niacin (Niaspan®) to Augment Subacute Ischemic Stroke Recovery | Ischemic stroke | Niacin (NPC167400) | NP level |
| NCT00000116 | Randomized Trial of DHA for Retinitis Pigmentosa Patients Receiving Vitamin A | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT02757898 | Transfusion of Biotinylated Red Blood Cells | anemia (phenotype) | Biotin (NPC199072) | NP level |
| NCT05457959 | Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant | glioma | Lysine (NPC112890) | NP level |
| NCT00345150 | Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls | hypertension | Arginine (NPC226453) | NP level |
| NCT01345474 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
| NCT00611000 | Effect of Folate on DNA in Colon Tissue and Blood Samples From Patients at Increased Risk of Developing Colorectal Neoplasia | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00944645 | MK0524A Bioequivalence Study (0524A-059) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01194453 | Pemetrexed Plus Cisplatin Versus Gemcitabine Plus Cisplatin for Advanced NSCLC Metastatic Non-small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01426438 | Endothelial Function, Lipoproteins, and Inflammation With Low HDL Cholesterol in HIV: ER Niacin Versus Fenofibrate | HIV-1 infection | Niacin (NPC167400) | NP level |
| NCT03101579 | Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer | leptomeningeal metastasis | Folic Acid (NPC147983) | NP level |
| NCT03510884 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02106650 | Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological Malignancies | unspecified peripheral T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT05276895 | Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis | osteoarthritis | Quercetin (NPC20791) | NP level |
| NCT00052715 | Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
| NCT00262730 | Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM | glioblastoma multiforme | Lysine (NPC112890) | NP level |
| NCT01417481 | Effect of Glycine in Cystic Fibrosis | cystic fibrosis | Glycine (NPC126681) | NP level |
| NCT01436266 | Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion | hemorrhage | Folic Acid (NPC147983) | NP level |
| NCT01468948 | Octanoic Acid for Essential Tremor | essential tremor | Octanoic Acid (NPC301696) | NP level |
| NCT00289900 | Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT01263041 | Effect of L-arginine and Glutamine on Preterm | Sepsis | Arginine (NPC226453) | NP level |
| NCT00618995 | A Study to Evaluate the Effects of ER Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites (0524A-079)(COMPLETED) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT04921189 | Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors | cardiac arrest | Thiamine (NPC150950) | NP level |
| NCT01183065 | Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC) | head and neck malignant neoplasia | Folic Acid (NPC147983) | NP level |
| NCT03509350 | Vitamin C, Thiamine, and Steroids in Sepsis | Sepsis | Thiamine (NPC150950) | NP level |
| NCT02930343 | Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02114502 | Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma | multiple myeloma | Pyridoxine (NPC269919) | NP level |
| NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients | prostate cancer | Rutin (NPC176740) | NP level |
| NCT00943124 | MK0524B Bioequivalence Study (0524B-070) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00703196 | Folic Acid Clinical Trial for the Prevention of Cervical Cancer | cervical cancer | Folic Acid (NPC147983) | NP level |
| NCT03356483 | Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study. | obsessive-compulsive disorder | Niacin (NPC167400) | NP level |
| NCT01983969 | Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma | cancer;lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT00275418 | Beta Carotene From Natural Source for Patients With Non-Active Crohn's Disease | Crohn's disease | Beta Carotene (NPC17810) | NP level |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | colorectal carcinoma | Pyridoxine (NPC269919) | NP level |
| NCT00817336 | Biomarkers in Schizophrenia | schizoaffective disorder;schizophrenia | Serine (NPC219143) | NP level |
| NCT00626392 | Study to Evaluate the EFFECTS of Acetylsalicylic Acid (ASA) on Niaspan®-Induced Flushing in Subjects With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT03446456 | Vasopressin and Pain Perception in the Brain | pain | Arginine (NPC226453) | NP level |
| NCT03272594 | The Influence of Breastfeeding on Cortical Activity During Procedures | pain | Sucrose (NPC130683) | NP level |
| NCT04478734 | Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease | Huntington disease | Thiamine (NPC150950);Biotin (NPC199072) | NP level |
| NCT01873443 | Long-Term Efficacy and Safety of CT-P10 in Patients With RA | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00223717 | Treatment of Supine Hypertension in Autonomic Failure | hypertension | Arginine (NPC226453) | NP level |
| NCT00470522 | Study of Methotrexate in Lupus Erythematosus | systemic lupus erythematosus | Folic Acid (NPC147983) | NP level |
| NCT00128557 | Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh | vitamin A deficiency | Retinol (NPC55412) | NP level |
| NCT00133419 | Micronutrients and Enteric Infections in African Children | infection | Retinol (NPC55412) | NP level |
| NCT01118624 | Study of Pralatrexate in Female Patients With Previously-treated Breast Cancer | breast carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01419067 | A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection | Craniopharyngioma | Methionine (NPC152451) | NP level |
| NCT00677339 | L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB) | pulmonary tuberculosis | Arginine (NPC226453) | NP level |
| NCT04616248 | In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors | breast carcinoma | Lysine (NPC112890) | NP level |
| NCT00004758 | Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment | epilepsy | Pyridoxine (NPC269919) | NP level |
| NCT01920191 | Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma | neoplasm | Lysine (NPC112890) | NP level |
| NCT00005658 | Glycine to Treat Psychotic Disorders in Children | schizophrenia | Glycine (NPC126681) | NP level |
| NCT00120289 | Niacin Plus Statin to Prevent Vascular Events | stroke;atherosclerosis;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT00485758 | Extended Niacin/Laropiprant in Patients With Type 2 Diabetes (0524A-069) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT00995085 | Efficacy Study of Metadoxine SR Formulation in Attention Deficit Hyperactivity Disorder (ADHD) Subjects | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT01104519 | A Study of Niaspan on Endothelium-Dependent and Endothelium-Independent Vascular Reactivity (0000-093) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01042535 | Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer | male breast carcinoma | Tryptophan (NPC203468) | NP level |
| NCT00974714 | L-arginine Effects on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT04952051 | Enalapril Folic Acid Tablets Combined With CCB or Diuretic to Prevent Stroke in Patients With Type H Hypertension | hypertension | Folic Acid (NPC147983) | NP level |
| NCT02563327 | Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT04703361 | Effects of Ketones and Niacin in Heart Failure Patients | systolic heart failure | Niacin (NPC167400) | NP level |
| NCT02220244 | Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis | multiple sclerosis | Biotin (NPC199072) | NP level |
| NCT03516903 | Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI | myocardial infarction | Folic Acid (NPC147983) | NP level |
| NCT04855266 | Iron Sucrose in Patients With Iron Deficiency and POTS | orthostatic hypotension | Sucrose (NPC130683) | NP level |
| NCT02516085 | Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT00344916 | Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT00554827 | Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma | Cutaneous T-cell lymphoma | Folic Acid (NPC147983) | NP level |
| NCT03872011 | Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock | septic shock | Thiamine (NPC150950) | NP level |
| NCT00763633 | B6 Treatment for Nausea and Vomiting in Pregnancy | Nausea and vomiting | Pyridoxine (NPC269919) | NP level |
| NCT05452772 | 5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder | nicotine dependence | Niacin (NPC167400) | NP level |
| NCT04740580 | Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease | Alzheimer disease | Glycine (NPC126681) | NP level |
| NCT04054973 | L-arginine Study for Persistent Symptoms of Schizophrenia | schizophrenia | Arginine (NPC226453) | NP level |
| NCT02961816 | Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT00499265 | Gemcitabine With or Without WX-671 in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery | pancreatic carcinoma | Serine (NPC219143) | NP level |
| NCT02467504 | Low-dose Recombinant Human IL-2 for the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT05378919 | Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer | rectum cancer | Folic Acid (NPC147983) | NP level |
| NCT03028467 | Evaluation of Pharmacokinetics and Safety of GSK3196165 in Combination With Methotrexate in Japanese Subjects With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00114400 | BVAIT: B-Vitamin Atherosclerosis Intervention Trial | atherosclerosis | Folic Acid (NPC147983);Pyridoxine (NPC269919) | NP level |
| NCT04631536 | Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC | COVID-19 | Folic Acid (NPC147983);Arginine (NPC226453) | NP level |
| NCT01839344 | Effects of Quercetin on Blood Sugar and Blood Vessel Function in Type 2 Diabetes. | type 2 diabetes mellitus | Quercetin (NPC20791) | NP level |
| NCT03606967 | Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer | breast carcinoma | Lysine (NPC112890) | NP level |
| NCT01850680 | Single Ascending Dose Study of Safety and Tolerability of Sarilumab and Methotrexate in Japanese Patients With Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01407432 | Impact of Folates in the Care of the Male Infertility | male infertility | Folic Acid (NPC147983) | NP level |
| NCT04476277 | Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease | sickle cell anemia | Biotin (NPC199072) | NP level |
| NCT04354428 | Treatment for COVID-19 in High-Risk Adult Outpatients | COVID-19 | Folic Acid (NPC147983) | NP level |
| NCT00047983 | Omega-3 Fatty Acids That Affect the Immune System in Kidney Transplant Patients | kidney disease | Arginine (NPC226453) | NP level |
| NCT00000482 | Coronary Drug Project | Myocardial Ischemia;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT02129075 | A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma | cutaneous melanoma | Lysine (NPC112890) | NP level |
| NCT00664287 | Extended Release (ER) Niacin/Laropiprant Add on Study (0524A-082) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04853199 | Quercetin In The Treatment Of SARS-COV 2 | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT00216099 | Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate Cancer | prostate cancer | Folic Acid (NPC147983) | NP level |
| NCT01984073 | Effects of Niacin On Fatty Acid Trapping | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00378833 | Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00243412 | A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00200746 | Treatment of Alcohol-Related Hepatitis With Arginine | Hepatitis, Alcoholic | Arginine (NPC226453) | NP level |
| NCT00951158 | A Molecular Pharmacodynamic Dose-titration Trial of Conjugated Linoleic Acid (CLA; Clarinol®) in Patients With Advanced Solid Tumors | neoplasm | Linoleic Acid (NPC85813) | NP level |
| NCT01005303 | Micronutrient Supplementation in Patients With Heart Failure | heart failure | Thiamine (NPC150950) | NP level |
| NCT01221402 | Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT02125786 | A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma | ependymoma | Methionine (NPC152451) | NP level |
| NCT01766219 | CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery | cholangiocarcinoma;gallbladder neoplasm | Octanoic Acid (NPC301696) | NP level |
| NCT04733534 | An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer | childhood cancer | Quercetin (NPC20791) | NP level |
| NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Quercetin (NPC20791) | NP level |
| NCT02017249 | Efficacy Study of Oral Arginine to Improve Immune Function in Glioblastoma Multiforme | glioblastoma multiforme | Arginine (NPC226453) | NP level |
| NCT00222235 | Adjunctive Treatment for Decreasing Symptoms of Schizophrenia | schizoaffective disorder;schizophrenia | Glycine (NPC126681) | NP level |
| NCT04900415 | Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction | COVID-19 | Retinol (NPC55412) | NP level |
| NCT02833350 | Safety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT03162562 | The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer | ovarian carcinoma | Lysine (NPC112890) | NP level |
| NCT03481790 | Lactoferrin Versus Ferrous Sulphate for Treatment of Iron Deficiency Anaemia During Pregnancy | Iron deficiency anemia | Folic Acid (NPC147983) | NP level |
| NCT03370159 | CPI-613 and Docetaxel in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer | non-small cell lung carcinoma | Octanoic Acid (NPC301696) | NP level |
| NCT01703104 | The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia | sickle cell anemia | Folic Acid (NPC147983) | NP level |
| NCT01792310 | A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours | glioma | Oleic Acid (NPC261831) | NP level |
| NCT05025488 | Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm | essential thrombocythemia;myelofibrosis | Lysine (NPC112890) | NP level |
| NCT01324115 | NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors | neoplasm | Arginine (NPC226453) | NP level |
| NCT03121677 | Personalized Tumor Vaccine Strategy and PD-1 Blockade in Patients With Follicular Lymphoma | follicular lymphoma | Lysine (NPC112890) | NP level |
| NCT00397917 | Oral Cleft Prevention Program | cleft lip;Cleft palate | Folic Acid (NPC147983) | NP level |
| NCT01217814 | Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01439555 | Endothelial Facilitation in Alzheimer's Disease | Alzheimer disease | Arginine (NPC226453) | NP level |
| NCT01070810 | Thiamine as a Metabolic Resuscitator in Septic Shock | septic shock | Thiamine (NPC150950) | NP level |
| NCT04946383 | Safety and Effectivness of Quercetin & Dasatinib on Epigenetic Aging | aging | Quercetin (NPC20791) | NP level |
| NCT00271817 | To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02393378 | Namilumab vs Adalimumab in Participants With Moderate to Severe Early Rheumatoid Arthritis Inadequately Responding to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01201954 | Pain Relief of Newborn Preterm Infants During Endotracheal Suctioning | pain | Sucrose (NPC130683) | NP level |
| NCT04907253 | Quercetin in Coronary Artery By-pass Surgery | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT00480207 | Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults | depressive disorder | Folic Acid (NPC147983) | NP level |
| NCT01287585 | Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy | hepatocellular carcinoma | Arginine (NPC226453) | NP level |
| NCT05096663 | Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00071266 | The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT03861416 | "Unifuzol®" in Patients With Peripheral Arterial Disease | peripheral arterial disease | Arginine (NPC226453) | NP level |
| NCT02903355 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
| NCT05363917 | Natrunix Versus Methotrexate in Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00202280 | Efficacy of Treating First Episode Psychosis With Folic Acid,B12 and B6 in Addition to Antipsychotic Medication | psychosis | Folic Acid (NPC147983);Pyridoxine (NPC269919) | NP level |
| NCT00154700 | Twice Weekly TP-HDFL for Recurrent or Metastatic Esophageal Cancer | esophageal cancer | Folic Acid (NPC147983) | NP level |
| NCT03581773 | Folic Acid Supplement Versus Placebo for Treating Mucositis Adverse Events in Metastatic Renal Cell Carcinoma Patients Receiving Targeted Therapy | mucositis | Folic Acid (NPC147983) | NP level |
| NCT00672360 | Folate Rechallenge | autism | Folic Acid (NPC147983) | NP level |
| NCT00054938 | Prevention of Atherosclerosis and Heart Disease in Patients With Systemic Lupus Erythematosis (SLE) | systemic lupus erythematosus | Folic Acid (NPC147983) | NP level |
| NCT00215917 | D-Serine Monotherapy for Schizophrenia | schizophrenia | Serine (NPC219143) | NP level |
| NCT00616304 | Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT01188096 | A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas | brain neoplasm | Lysine (NPC112890) | NP level |
| NCT02093026 | Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01569919 | A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma | mesothelioma | Folic Acid (NPC147983) | NP level |
| NCT05062486 | A Study to Evaluate the Safety and Efficacy of RQC for AMD | age-related macular degeneration | Quercetin (NPC20791) | NP level |
| NCT00491569 | Sarcosine or D-Serine Add-on Treatment for Chronic Schizophrenia | schizophrenia | Serine (NPC219143) | NP level |
| NCT00143702 | D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE) | lactic acidosis | Thiamine (NPC150950) | NP level |
| NCT00536237 | MK0524A Phase IIb Study (0524A-011)(COMPLETED) | Flushing | Niacin (NPC167400) | NP level |
| NCT05284656 | Effect of Folic Acid and/or Pentoxifylline on Patients With Chronic Kidney Disease | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT00000152 | Randomized Trial of Beta-Carotene and Macular Degeneration | macular degeneration | Beta Carotene (NPC17810) | NP level |
| NCT03718507 | Study on the Effects of Different Premedication for LISA on Stress and Cerebral Tissue Oxygenation in Preterm Infants | acute respiratory distress syndrome | Sucrose (NPC130683) | NP level |
| NCT04364750 | Biomarkers of Diet-microbiota Interactions in Irritable Bowel Syndrome | irritable bowel syndrome | Histidine (NPC237812) | NP level |
| NCT00908791 | Proof of Principle Trial to Determine if Nutritional Supplement Conjugated Linoleic Acid (CLA) Can Modulate the Lipogenic Pathway in Breast Cancer Tissue | breast cancer | Linoleic Acid (NPC85813) | NP level |
| NCT00005107 | Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT00000461 | Harvard Atherosclerosis Reversibility Project (HARP) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT03509662 | Vitamin C in Post-cardiac Arrest | cardiac arrest | Thiamine (NPC150950) | NP level |
| NCT02440061 | Ghrelin and Beta Cell Function in Diabetes | type 2 diabetes mellitus | Arginine (NPC226453) | NP level |
| NCT03172325 | Study to Demonstrate Non-Inferior Efficacy and Safety of CinnoRA® Versus Humira® for Treatment of Active RA | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01871766 | Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy | rhabdomyosarcoma | Methionine (NPC152451) | NP level |
| NCT01561547 | Trial of Repeated Analgesia With Kangaroo Care | pain | Sucrose (NPC130683) | NP level |
| NCT01134341 | Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma | anaplastic large cell lymphoma;mycosis fungoides;Sezary's disease | Folic Acid (NPC147983) | NP level |
| NCT04249336 | Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH | allergic disease | Arginine (NPC226453) | NP level |
| NCT00268749 | Glycine Treatment of Prodromal Symptoms | schizophrenia | Glycine (NPC126681) | NP level |
| NCT02472626 | 6,8-Bis(Benzylthio)Octanoic Acid, Cytarabine, and Daunorubicin Hydrochloride in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia | acute myeloid leukemia | Octanoic Acid (NPC301696) | NP level |
| NCT01438320 | Q-Trial in Patients With Hepatitis C | chronic hepatitis C virus infection | Quercetin (NPC20791) | NP level |
| NCT01243242 | Clinical Efficacy & Safety, of Metadoxine (MG01CI) Extended Release in Attention-Deficit Hyperactivity Disorder (ADHD) | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT00344734 | Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure | congestive heart failure | Arginine (NPC226453) | NP level |
| NCT03444298 | A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults | asthma;inflammation | (2R)-2,7,8-Trimethyl-2-[(4R,8R)-4,8,12-Trimethyltridecyl]-3,4-Dihydrochromen-6-Ol (NPC48623) | NP level |
| NCT00519207 | Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture | pain | Sucrose (NPC130683) | NP level |
| NCT00300352 | Effect of Folic Acid Treatment in Coronary Artery Disease | coronary artery disease | Folic Acid (NPC147983) | NP level |
| NCT00266227 | A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01116141 | A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02878265 | The Effect of Vitamin A With and Without Zinc and Multivitamin Supplementation on Malaria Morbidity in Ghanaian Children | malaria | Retinol (NPC55412) | NP level |
| NCT00152893 | To Determine if Chromium Nicotinate Supplementation Will Improve Insulin Resistance in HIV Patients With Metabolic Abnormalities | HIV infection | Niacin (NPC167400) | NP level |
| NCT00000553 | HDL-Atherosclerosis Treatment Study (HATS) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT03943459 | Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT03580122 | The Effect of Arginine on Classic Galactosemia | classic galactosemia | Arginine (NPC226453) | NP level |
| NCT00408577 | Prevention of Cardiac and Vascular Events in Patients With NGT/IGT. | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT02612259 | A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity | obesity | Tryptophan (NPC203468) | NP level |
| NCT03228524 | D-aspartate and Therapeutic Exercise | brain injury | D-Aspartate (NPC285322) | NP level |
| NCT01490944 | Impact of Vitamin B12 Supplementation With Iron and Folic Acid on Adolescent Girls | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT01468038 | A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food | Sleep Disorder | L-Glutamate (NPC137958) | NP level |
| NCT04301336 | Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia | sickle cell anemia | Folic Acid (NPC147983) | NP level |
| NCT01054508 | Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02586285 | Effect of S-Adenosyl Methionine Treatment on Recurrence After Curative Resection of Hepatocellular Carcinoma | hepatocellular carcinoma | Methionine (NPC152451) | NP level |
| NCT00973609 | Optimal Maintenance Therapy With Bevacizumab After Induction in Metastatic Colorectal Cancer (CRC) | colorectal neoplasm | Folic Acid (NPC147983) | NP level |
| NCT01685281 | Study Comparing Two Doses of MG01CI and Placebo in Adults With Predominantly Inattentive Attention Deficit Hyperactivity Disorder | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT00157521 | L-Arginine in Pre-Eclampsia | preeclampsia | Arginine (NPC226453) | NP level |
| NCT05456022 | Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line | mouth neoplasm | Quercetin (NPC20791) | NP level |
| NCT00731588 | Red Blood Cell (RBC) Survival Following Transfusion in Infants | neonatal anemia | Biotin (NPC199072) | NP level |
| NCT01238471 | Oral Propranolol Versus Placebo for Early Stages of Retinopathy of Prematurity: A Randomized and Prospective Study | retinopathy of prematurity | Sucrose (NPC130683) | NP level |
| NCT00058123 | Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma | Central Nervous System Neoplasm | Lysine (NPC112890) | NP level |
| NCT00301587 | A Study to Evaluate Folate Levels in Women Taking Oral Contraceptives | neural tube defect | Folic Acid (NPC147983) | NP level |
| NCT01835782 | Determining the Safety of L-serine in ALS | amyotrophic lateral sclerosis | Serine (NPC219143) | NP level |
| NCT00630877 | Evaluation of a Flushing ASsessment Tool (FAST) in Subjects Receiving Niacin Extended-release Plus Aspirin | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01661764 | Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention | colorectal adenoma | Oleic Acid (NPC261831) | NP level |
| NCT02109614 | Early Aortic Valve Lipoprotein(a) Lowering Trial | aortic stenosis | Niacin (NPC167400) | NP level |
| NCT01607879 | Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation | prostate cancer | Arginine (NPC226453) | NP level |
| NCT02379091 | Dose Finding Study of Namilumab in Combination With Methotrexate in Participants With Moderate to Severe Rheumatoid Arthritis (RA) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT05042024 | Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis | periodontitis | Arginine (NPC226453) | NP level |
| NCT01912820 | Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery | prostate adenocarcinoma | Quercetin (NPC20791) | NP level |
| NCT04703036 | Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19 | COVID-19 | Glycine (NPC126681) | NP level |
| NCT02618824 | Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery | congenital heart disease | Tryptophan (NPC203468);Histidine (NPC237812) | NP level |
| NCT01900431 | Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis | uveitis | Folic Acid (NPC147983) | NP level |
| NCT02063802 | Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children | obesity | Linoleic Acid (NPC85813) | NP level |
| NCT00806819 | Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT04677049 | Study of Niacin in Glioblastoma | glioblastoma multiforme | Niacin (NPC167400) | NP level |
| NCT00000599 | Cholesterol-Lowering Atherosclerosis Study (CLAS) | carotid artery disease;cerebral atherosclerosis;Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00638196 | Placebo vs. Linoleic Acid Controlled Assessment of Treatment Efficacy in MS | multiple sclerosis | Oleic Acid (NPC261831) | NP level |
| NCT00533312 | MK0524A Clinical Efficacy Study (0524A-026)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT03540758 | Regulation of Endogenous Glucose Production by Central KATP Channels | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT00134433 | Endothelial Modulation for Angiogenic Therapy | coronary artery disease | Arginine (NPC226453) | NP level |
| NCT03887169 | Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. | pulmonary alveolar proteinosis | Pyridoxine (NPC269919);Folic Acid (NPC147983);Methionine (NPC152451) | NP level |
| NCT03450707 | Thiamine as a Metabolic Resuscitator After Cardiac Arrest | cardiac arrest | Thiamine (NPC150950) | NP level |
| NCT00804843 | Merck Carotid Atherosclerosis Trial (MK-0000-111)(COMPLETED) | carotid atherosclerosis | Niacin (NPC167400) | NP level |
| NCT02702492 | PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA) | non-Hodgkins lymphoma | Niacin (NPC167400) | NP level |
| NCT03882177 | StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis | pulmonary tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT01908452 | Pyridoxal Kinase Activity in Tardive Dyskinesia | movement disorder | Pyridoxine (NPC269919) | NP level |
| NCT01708278 | Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT02756117 | The Effect of Acute Lysine Administration on α-aminoadipic Acid | prediabetes syndrome | Lysine (NPC112890) | NP level |
| NCT03745963 | The Influence of Skin-to-skin Contact on Cortical Activity During Painful Procedures on Preterm Infants in the NICU | pain | Sucrose (NPC130683) | NP level |
| NCT00728910 | Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02890992 | An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00571766 | Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT00787059 | AC6 Gene Transfer for CHF | congestive heart failure | Sucrose (NPC130683) | NP level |
| NCT04851821 | The Effectiveness of Phytotherapy in SARS-COV2(COVID-19) | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT01266018 | Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer | small cell lung carcinoma | Arginine (NPC226453) | NP level |
| NCT00338221 | Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition | malnutrition | Glycine (NPC126681) | NP level |
| NCT02484391 | CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma | Granulocytic Sarcoma | Octanoic Acid (NPC301696) | NP level |
| NCT00108589 | S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis | Hepatitis | Methionine (NPC152451) | NP level |
| NCT03752918 | The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD. | post-traumatic stress disorder | Niacin (NPC167400) | NP level |
| NCT01140646 | Evaluation of SAMe for Hot Flashes | Hot flashes | Methionine (NPC152451) | NP level |
| NCT00002650 | High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed | colorectal carcinoma | Folic Acid (NPC147983) | NP level |
| NCT00137124 | L-Arginine Metabolism in Essential Hypertension | essential hypertension | Arginine (NPC226453) | NP level |
| NCT01381354 | Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) | multiple sclerosis | Thiamine (NPC150950) | NP level |
| NCT01503060 | Effectiveness of Parent-Led Interventions in Reducing Infant Hypersensitivity to Pain | pain | Sucrose (NPC130683) | NP level |
| NCT02947750 | Neurovascular Transduction During Exercise in Chronic Kidney Disease | chronic kidney disease | Folic Acid (NPC147983) | NP level |
| NCT00298272 | Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00508989 | Niacin to Improve Blood Flow in People With Sickle Cell Disease | sickle cell anemia | Niacin (NPC167400) | NP level |
| NCT00807807 | Evaluating the Effects of Folic Acid Supplementation in Older Adults: The Folic Acid Supplementation Trial (The FAST Study) | heart disease | Folic Acid (NPC147983) | NP level |
| NCT00133406 | Long-term Impact and Intervention for Diarrhea in Brazil | diarrheal disease | Retinol (NPC55412);Glycine (NPC126681) | NP level |
| NCT01115504 | Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy | heart failure | Thiamine (NPC150950) | NP level |
| NCT00065455 | Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT03679780 | The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT00607945 | Dietary Fatty Acids as Complementary Therapy in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Linoleic Acid (NPC85813) | NP level |
| NCT02220933 | Effect of MD1003 in Spinal Progressive Multiple Sclerosis | multiple sclerosis | Biotin (NPC199072) | NP level |
| NCT00029679 | Borage Oil and Ginkgo Biloba (EGb 761) in Asthma | asthma | Linoleic Acid (NPC85813) | NP level |
| NCT02291458 | L-arginine and Brown Adipose Tissue | Glucose intolerance | Arginine (NPC226453) | NP level |
| NCT00000161 | Randomized Trials of Vitamin Supplements and Eye Disease | cataract;macular degeneration | Beta Carotene (NPC17810) | NP level |
| NCT02447874 | Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT02762838 | Comparative Clinical Trial of Efficacy and Safety of BCD-055 and Remicade® in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01720095 | Niapsan as Add -on Therapy to Antipsychotic Treatment in First Episode Psychosis | psychosis | Niacin (NPC167400) | NP level |
| NCT01142219 | L-Arginine and Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT04345705 | Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma | mesothelioma | Lysine (NPC112890) | NP level |
| NCT01936831 | High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB) | tuberculosis | Pyridoxine (NPC269919) | NP level |
| NCT01061736 | Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01368328 | Effect of the Chromium Nicotinate on Type 2 Diabetes | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | myocardial infarction;Myocardial Ischemia | Pyridoxine (NPC269919);Folic Acid (NPC147983);Beta Carotene (NPC17810) | NP level |
| NCT00475176 | S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis C | chronic hepatitis C virus infection | Methionine (NPC152451) | NP level |
| NCT00280683 | Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma | asthma | Arginine (NPC226453) | NP level |
| NCT00000114 | Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa | retinitis pigmentosa | Retinol (NPC55412) | NP level |
| NCT03268733 | The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome | polycystic ovary syndrome | Folic Acid (NPC147983) | NP level |
| NCT00024310 | Paclitaxel, Folic Acid, and Lometrexol in Treating Patients With Locally Advanced or Metastatic Solid Tumors | neoplasm | Folic Acid (NPC147983) | NP level |
| NCT01670955 | The Safety and Effectiveness of Jobelyn in Pre-operative Management of Anaemia in Gynaecological Patients | anemia (phenotype) | Folic Acid (NPC147983) | NP level |
| NCT02293902 | A Study Assessing the Efficacy and Safety of Sarilumab Added to MTX in Japanese Patients With Moderately to Severely Active Rheumatoid Arthritis (SARIL-RA-KAKEHASI) | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT02744820 | Multiple Ascending Dose Study of GMC-252-L-Lys Salt in Healthy Subjects and Type 2 Diabetics | type 2 diabetes mellitus | Lysine (NPC112890) | NP level |
| NCT00300365 | Pioglitazone vs Placebo in Combination With Niacin Extended Release on Low HDL | metabolic syndrome | Niacin (NPC167400) | NP level |
| NCT03580616 | Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Sclerosis (ALS) | amyotrophic lateral sclerosis | Serine (NPC219143) | NP level |
| NCT01321034 | Effect of Niacin in the Lipoprotein (a) Concentration | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT04764383 | Histaminergic Basis of Fatigue in Multiple Sclerosis | multiple sclerosis | Histidine (NPC237812) | NP level |
| NCT02936037 | Effect of MD1003 in Progressive Multiple Sclerosis (SPI2) | multiple sclerosis | Biotin (NPC199072) | NP level |
| NCT03640949 | Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest | sudden cardiac arrest | Arginine (NPC226453) | NP level |
| NCT00929370 | A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam. | schizophrenia | Glycine (NPC126681) | NP level |
| NCT03166228 | Hemodynamic Changes During Operative Hysteroscopy | hypertension | Glycine (NPC126681) | NP level |
| NCT01071291 | Effects of Niaspan™ on High-density Lipoprotein (HDL) in Healthy Male Subjects (0000-069) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01976676 | Folic Acid vs 5-methyltetrahydrofolate (5MTHF) in Recurrent Abortion | habitual abortion | Folic Acid (NPC147983) | NP level |
| NCT00299130 | A Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Active Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT01711359 | A Study in Participants With Moderate to Severe Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00573313 | Effects of SAMe in Patients With Alcoholic Liver Disease | liver disease | Methionine (NPC152451) | NP level |
| NCT04989049 | Therapeutic Effect of Folic Acid in Healing of Oral Ulcers | Oral ulcer | Folic Acid (NPC147983) | NP level |
| NCT00781196 | Folic Acid Supplementation in Phenytoin Induced Gingival Overgrowth | gingival overgrowth | Folic Acid (NPC147983) | NP level |
| NCT00917826 | Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies | lymphoma | Arginine (NPC226453) | NP level |
| NCT02504671 | Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00578305 | A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
| NCT00056225 | VITAL - VITamins to Slow ALzheimer's Disease (Homocysteine Study) | Alzheimer disease | Pyridoxine (NPC269919);Folic Acid (NPC147983) | NP level |
| NCT02701673 | Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma | lymphoma | Pyridoxine (NPC269919) | NP level |
| NCT03090048 | Vitamin A and Azithromycin for Acne Vulgaris | acne | Retinol (NPC55412) | NP level |
| NCT00272610 | Topical Vitamin A Versus Vehicle Cream in the Treatment of Aged Skin | Purpura | Retinol (NPC55412) | NP level |
| NCT03427086 | Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis | amyotrophic lateral sclerosis | Biotin (NPC199072) | NP level |
| NCT00575848 | Study of the Effects of Glycine on Symptoms and Memory in Patients With Schizophrenia | schizoaffective disorder;schizophrenia | Glycine (NPC126681) | NP level |
| NCT00397657 | Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT02773147 | Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma Homocysteine | HIV infection | Pyridoxine (NPC269919);Folic Acid (NPC147983) | NP level |
| NCT00203476 | A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT02699099 | Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. | malaria | Retinol (NPC55412) | NP level |
| NCT01165021 | A Study of Pemetrexed/Cisplatin as Pre-operative Treatment of Early Stage Nonsquamous Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Folic Acid (NPC147983) | NP level |
| NCT01796678 | Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial | pain | Arginine (NPC226453) | NP level |
| NCT03068832 | Neoepitope-based Personalized Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors | brain neoplasm | Lysine (NPC112890) | NP level |
| NCT02189772 | Safety and Tolerability Study of Metadoxine Extended Release (MDX) (Previously Known as MG01CI) in PI-ADHD Adolescent Subjects | attention deficit hyperactivity disorder | Pyridoxine (NPC269919) | NP level |
| NCT00957359 | Psilocybin Cancer Anxiety Study | cancer | Niacin (NPC167400) | NP level |
| NCT00276263 | Sarcosine Preventive Therapy for Individuals At High Risk for Schizophrenia | schizophrenia | Glycine (NPC126681) | NP level |
| NCT02318446 | Efficacy Study of Folic Acid Supplementation in Adolescent Epileptics | epilepsy | Folic Acid (NPC147983) | NP level |
| NCT02795299 | Study Evaluating Gerilimzumab´s Safety/Efficacy for Patients MTX or TNFα Antagonist Failed in Rheumatoid Arthritis | rheumatoid arthritis | Folic Acid (NPC147983) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
GRIA2,GRIA4,GRIA1,SRC,GRIN2B,GRIA3,ACHE,GRM5,SNCA
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
NFKB1,AXL,TP53,PIM1,FLT3,AURKB,SRC
NCT01842139,NCT02472626 |
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT02447874,NCT00513617,NCT00508989,NCT01703104,NCT00056433,NCT05470998,NCT04301336,NCT01142219,NCT04476277
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
CYP1A1,GRM8,SLCO1B1,F2,SLCO1B3,NOX4,HCAR2,MET,NPSR1
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
NOX4,HCAR2,ALOX5,GRIK3,CYP1B1,XDH,GRIA2,MET,FFAR1
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PPARA
NCT01583647,NCT00652431,NCT00203476,NCT00384293,NCT00376584,NCT00536510,NCT00378833 |
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
F2,KDR,PPARA,HCAR2,MET,SRC
NCT00408577,NCT03679780 |
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
NOX4,OR51E2,SLCO1B1,GRIN3A,ALOX15,SLCO1B3,FABP5
NCT01912820 |
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
NOX4,AKR1C3,SLCO1B1,F2,FABP4,SLCO1B3,AURKB,NPSR1
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
GRM1,ACHE,AXL,HCAR2,NFKB1,CYP19A1,GRIN3A,MET
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
ACHE,SNCA,LMNA,CA2,GSTP1,SRC,FABP3,GRIK1
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ACHE,NOX4,SLCO1B1,ALOX15,SLCO1B3,CDK1,AURKB,NPSR1
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CA2,SLCO1B1,CYP3A4,AKR1B1,CDK1,SLCO1B3,AURKB,CYP1A2
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
EGFR
NCT02961816,NCT01983969,NCT02589145,NCT00917826,NCT00998946,NCT02701673 |
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
IGF1R,XDH
NCT02947750,NCT01356966,NCT05284656,NCT00047983,NCT02848131 |
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
AKR1B1,GRIN2B,CYP19A1,GRIA4,GRIA1,GRIA2,GRIA3
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT01324115,NCT00567931,NCT00951158,NCT01191216,NCT01920191,NCT00024310,NCT01057589
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ACHE,CYP1A1,SLC1A1,YES1,FFAR1
NCT00054938,NCT00470522 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT02825901
NCT00223717,NCT03166228,NCT04952051,NCT00345150,NCT00520247 |
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
TP53,SRC,FLT3,KDR,MET
NCT01188876 |
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
KDR,GSTP1,AXL,TP53,EGFR
NCT01902381 |
NADisease Category: NADisease ICD-11 Code: NA |
MET,NOX4
NCT00071266,NCT00781196,NCT00062556,NCT03444298 |
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
MAPK1,TP53,SRC,IGF1R,GSTP1,EGFR
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
IGF1R,KDR,FLT3,SRC,AXL
NCT02114502 |
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
GRM3,GRM2
NCT02612259,NCT01083329,NCT00204932,NCT02063802 |
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
F2,ALOX5
NCT00280683,NCT01501942,NCT03444298,NCT00029679 |
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
NCT00120289,NCT01221402,NCT00397657,NCT00127218,NCT00114400,NCT00150722
|
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT00000482,NCT00000541,NCT00000599,NCT00000512,NCT00000553,NCT00000461
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04631536,NCT04354428,NCT04703036,NCT04853199,NCT04851821,NCT04900415
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ACHE,CA2,CYP1A1,CA14,GRM8,ALOX15
|
Dissociative neurological symptom disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B60 |
GRIK1,GRIN2B,GRIN1,GRIA1,GRIN2A
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
MET,SRC,TP53,KDR,EGFR
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
GRIN2B,GRM2,GRIK1
NCT02318446,NCT00004758 |
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
FFAR1,KDR,AURKB,AKR1B1,PPARA
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
XDH,CA2
NCT01005303,NCT04703361,NCT01115504 |
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
FLT3,SRC,TP53,CDK1,AURKB
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
ALOX5,KDR,F2
NCT00272610,NCT05025488 |
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
GRIN1
NCT01936831,NCT00170404,NCT02563327,NCT01785186 |
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
MET,TP53,KDR,EGFR
NCT01183065 |
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
MET,CSNK2A1,KDR,EGFR,IGF1R
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
AURKB,AKR1C3
NCT01705652,NCT00216099,NCT01607879 |
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
EGFR,MET,KDR,MAPK1
NCT01783431 |
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
F2
NCT03516903,NCT00000541,NCT00000482,NCT00120289 |
Cardiac arrestDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC82 |
GRIN2B
NCT03640949,NCT03450707,NCT04921189,NCT03509662 |
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
NCT02878265,NCT00147368,NCT00616304,NCT00120822,NCT02699099
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
NCT02189772,NCT01685281,NCT00995085,NCT01243242,NCT02086864
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00957359,NCT04733534,NCT01983969,NCT00034463,NCT00441870
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT00000161,NCT00000152,NCT05062486,NCT03478878,NCT03478865
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
NOX4,FLT3,TSHR,AKR1B1,GRIN3A
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
GRM1,ABCG2,CA14,F2,GRIA1
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
AKR1C3,XDH,CDK1,SLCO1B3,AURKB
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
SLC1A1,GRM8,GRIA2,CDK1,AURKB
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
NOX4,AKR1C3,GRIA4,GRIN3A,GRM5
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
HCAR2,GRIN2B,F2
NCT00796887 |
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
TP53,KDR,MET,EGFR
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
SRC,AXL,EGFR,TP53
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
MET,ACHE,CA2,AKR1B1
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
SRC,TP53
NCT00703196,NCT00220532 |
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
SRC,KDR,FLT3,TP53
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
GRIN2B,EGFR,KDR,FLT3
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
NFKB1,ALOX5,FLT3
FABP5 |
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT00152893,NCT01949116,NCT02018965,NCT02773147
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT04999137,NCT01263041,NCT03509350,NCT03333278
|
AnemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00-3A9Z |
NCT01670955,NCT00953134,NCT01490944,NCT02757898
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT00300352,NCT00134433,NCT03943459,NCT04907253
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT03333278,NCT01070810,NCT04999137,NCT03872011
|
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT04201873,NCT04677049,NCT00262730,NCT02017249
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
SLCO1B3,HCAR2,GRIN3A
NCT00275418 |
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
HCAR2,TSHR,CYP1A1,CDK1
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
SLCO1B3,NOX4,HCAR2,GRIN3A
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
GRM3,GRIA2,CDK1,GRIK1
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
FLT3,MET,AXL,FFAR1
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
NOX4,OR51E2,CYP1B1,FFAR4
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
HCAR2,ACHE,MET,AXL
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ABCG2,NFKB1,AKR1B1,CA2,ALOX5
NCT02467504,NCT00299130,NCT02293902,NCT01711359,NCT02504671,NCT00578305,NCT01873443,NCT00299104,NCT00266227,NCT03172325,NCT02093026,NCT00950989,NCT03028467,NCT02393378,NCT02762838,NCT02930343,NCT02795299,NCT01217814,NCT05363917,NCT04535427,NCT01061736,NCT00298272,NCT02833350,NCT01850680,NCT00243412,NCT01010581,NCT01116141,NCT00965653,NCT02379091 |
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
ACHE,NR1I2,SNCA,AKR1C3,CA2,GRM8,ALOX15,FABP3,ABCG2,SLC1A1,OR51E2,F2,GSTP1,POLB,XDH,SLCO1B3,RECQL,PIM1,LMNA,GRIK3,CYP1B1,FFAR4,AXL,HCAR2,APP,ALOX5,CA14,MET,AURKB,NPSR1
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
EGFR,KDR,MET
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
GRM2,GRM5,CYP3A4
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
MET,EGFR,KDR
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
ALOX5,CDK1,EGFR
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
TSHR,KDR,MET
|
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
ALOX5,FLT3,FFAR1
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
SRC,KDR,MET
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
ABCG2,NFKB1
NCT04364750 |
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
ALOX5,NFKB1,CYP3A4
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
PPARA
FABP4 NCT02541045 |
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
HCAR2,TP53,MET
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA14,GRIN1,CA2
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
GRIN2B,GRM2,GRM3
|
Obsessive-compulsive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B20 |
GRIN1
NCT03356483,NCT01031927 |
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
TP53,SRC
NCT01188876 |
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
NCT00571766,NCT00974714,NCT00157521
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT01287585,NCT02586285,NCT05281926
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
NCT01118624,NCT03606967,NCT04616248
|
Mixed hyperlipidaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.2 |
NCT00269204,NCT00289900,NCT00269217
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
NCT00222235,NCT00575848,NCT00817336
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT01417481,NCT01348204,NCT00405665
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
NCT00058123,NCT00052715,NCT01233492
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT00133562,NCT00338221,NCT00396500
|
Neuropathy, ataxia, and retinitis pigmentosaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C73.1 |
NCT00065455,NCT00000116,NCT00000114
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT01835782,NCT03580616,NCT03427086
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
PIM1,GRIK1,TSHR
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
AURKB,NR1I2,ABCG2
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
GRM1,CYP1A1,GRM8
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
GRM1,ABCG2,GRM8
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
GRM2,ABCG2,CYP1B1
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
NR1I2,CA2,HSD17B10,GRM8,GRM3,CYP19A1,GRIN3A,AKR1B1,ALOX15,FFAR1,GRIA4,GSTP1,POLB,XDH,GRIK3,FFAR4,YES1,GRM1,HCAR2,TSHR,CA14,TP53,GRIK1,FABP5,GRIA1,MET,AURKB,NPSR1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
ACHE,KDR,NR1I2,HSD17B10,GRM8,GRIN3A,AKR1B1,CSNK2A2,FABP3,FFAR1,OR51E2,GSTP1,RECQL,NOX4,LMNA,GRIK3,EGFR,CDK1,AXL,TSHR,PPARA,TP53,FABP4,FABP5,SRC,MET,AURKB
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
FLT3,PIM1,TP53,PPARA,XDH,NFKB1,CYP3A4,AURKB,ALOX5,POLB,MAPK1,CSNK2A1,CA14,MET,CA2,CDK1,EGFR,IGF1R,GSTP1,SRC,KDR,AXL,APP,YES1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
NR1I2,CA2,ALOX15,FABP3,SLC1A1,GSTP1,XDH,GRIA2,SLCO1B3,NOX4,GRIK5,GRIK3,ALOX12,FFAR4,YES1,CYP1A2,GRM1,HCAR2,TSHR,ALOX5,CSNK2A3,TP53,FABP5,MET
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
KDR,SNCA,ALOX15,CSNK2A2,FFAR1,SLC1A1,OR51E2,AURKB,GSTP1,XDH,RECQL,PIM1,LMNA,EGFR,CDK1,FFAR4,HCAR2,ALOX5,GRIK1,FLT3,SRC,MET,AXL
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
ACHE,SNCA,CA2,GRM8,GRIN3A,GRIA4,SLC1A1,OR51E2,GRM2,XDH,GRIA2,NOX4,GRIK5,GRIK3,GRM1,APP,CA14,FABP5,GRIA1,MET,GRIK1
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ACHE,GRM8,CYP19A1,XDH,FFAR4,GRM5,ALOX5,FABP5,MET,AURKB,TSHR,ALOX5,GRIA4,GRIK3,GRM8,OR51E2,F2,FABP5,FFAR4,AURKB
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ACHE,KDR,SNCA,MAPK1,AKR1B1,FABP3,ABCG2,SLC1A1,SLCO1B1,F2,XDH,NOX4,ALOX12,CDK1,APP,ALOX5,CA14,FABP5,MET,NPSR1
|
DyslipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80-5C81 |
PPARA,HCAR2
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
APP,IGF1R
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
ALOX5,NFKB1
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
IGF1R,ALOX5
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
XDH,PPARA
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
F2,EGFR
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
CDK1,FLT3
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
EGFR,SRC
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
SRC,FLT3
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
NCT00137124 |
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
F2,GRIN2A
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
SRC,TP53
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
F2
NCT00120289 |
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
SRC,KDR
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB9Z |
MET
NCT00573313 |
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
IGF1R,SRC
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
SRC,ALOX5
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NFKB1,PPARA
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TP53
NCT00154700 |
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AKR1B1,F2
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
MET,EGFR
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
GRM2
NCT01720316 |
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
GRIK1,ACHE
|
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
FLT3,SRC
|
Gastrointestinal stromal tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5B |
KDR,SRC
|
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
MET
NCT00807807 |
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
ALOX5,XDH
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
HCAR2,PPARA
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
GRM2,GRM3
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
GRM5
NCT00672360 |
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
NCT00000161 |
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT03866174,NCT04630964
|
Cleft palateDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA42 |
NCT00098319,NCT00397917
|
Other specified infectious meningitis not elsewhere classifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D01.Y |
NCT03101579,NCT05289908
|
Noise effects on inner earDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB37 |
NCT02903355,NCT01345474
|
FlushingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME64.4 |
NCT00536237,NCT00533611
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT02618824,NCT03088345
|
Primary neoplasms of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
NCT03068832,NCT01188096
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FFAR4
NCT03268733 |
Pleural mesotheliomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26 |
NCT01569919,NCT04345705
|
Peripheral T-cell lymphoma, not otherwise specifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90.C |
NCT02013362,NCT02106650
|
Spina bifida, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA02.Z |
NCT00301587,NCT00452829
|
Cleft lipDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA40 |
NCT00098319,NCT00397917
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT05422885,NCT04946383
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT01438320,NCT00475176
|
Iron deficiency anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00 |
NCT02541708,NCT03481790
|
Retinal vascular occlusionDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B74 |
NCT00493064,NCT00500045
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT00344916,NCT00005107
|
Schizophrenia or other primary psychotic disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A2Z |
NCT00202280,NCT01720095
|
Tuberculosis of the respiratory systemDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10 |
NCT00677339,NCT03882177
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
NCT03121677,NCT00455416
|
Dental cariesDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA08.0 |
NCT02388178,NCT04750902
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00344734,NCT00787059
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
NCT01407432,NCT00406874
|
Cutaneous T-cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1951 |
NCT00554827,NCT02061449
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
NCT03752918,NCT00215878
|
Small cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.1 |
NCT01931787,NCT01266018
|
Other specified haemorrhagic or haematological disorders of fetus or newbornDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA8Y |
NCT00731588,NCT02075970
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT01708278,NCT03989271
|
Glioma, malignantDisease Category: X.Extension CodesDisease ICD-11 Code: XH4RQ3 |
NCT05457959,NCT01792310
|
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT02516085,NCT01388764
|
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT03956056,NCT00499265
|
Essential tremor or related tremorsDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04.1 |
NCT01468948,NCT00848172
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE,AXL
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
NOX4,FABP4
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
MET,HCAR2
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
AKR1B1,IGF1R,ACHE,ALOX5,GRIK1
NCT00482560,NCT01796678,NCT03446456,NCT03272594,NCT03082001,NCT01561547,NCT00949104,NCT01190995,NCT03745963,NCT02174705,NCT00519207,NCT02990364,NCT01503060,NCT01201954 |
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
GRM2,AKR1B1,GRM3,GRM5
NCT00000372,NCT00291226,NCT00215917,NCT00929370,NCT02067975,NCT00005658,NCT00268749,NCT00575848,NCT04054973,NCT00222235,NCT00817336,NCT00276263,NCT00491569 |
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
HCAR2,PPARA
NCT00111891,NCT00376584,NCT00630877,NCT01984073,NCT01104519,NCT01071291,NCT00664287,NCT00944645,NCT00961636,NCT03510884,NCT00728910,NCT00626392,NCT00943124,NCT00903617,NCT02890992 |
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
AKR1B1,OR51E2,GRM2,GSTP1,NOX4,LMNA,GRIK5,ALOX12,CDK1,GRM5,ALOX5,CSNK2A3,TP53,FABP5,SRC,IGF1R,AURKB
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
KDR,GSTP1,TP53,IGF1R,EGFR,MET,FLT3
NCT04337879,NCT00096330,NCT02066688,NCT00973609,NCT00070434,NCT01426490,NCT00002650,NCT00611000,NCT01661764 |
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
CYP19A1,GRM3,AKR1B1,FABP3,OR51E2,GSTP1,GRIA2,NOX4,CDK1,GRM1,FABP4,FABP5,GRIA1,SRC,IGF1R,AURKB
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
F2,PPARA,FFAR1,NFKB1
NCT00485758,NCT01839344,NCT00618995,NCT03685773,NCT03540758,NCT00607945,NCT01368328,NCT02440061,NCT02744820,NCT05210504,NCT02786823 |
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
NOX4,AKR1C3,OR51E2,CYP19A1,FABP4,GRM2,GRIA2,FABP5,CDK1,AURKB,AKR1C3,CYP19A1,CDK1,SRC,AURKB
|
HypercholesterolaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.0 |
NCT00269217,NCT00378833,NCT00203476,NCT01054508,NCT03510715,NCT00536510,NCT00652431,NCT00533312,NCT01321034,NCT00080275,NCT00082251,NCT01071525,NCT00271817,NCT00769132
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
SNCA,GRM3,APP,MET,GRM5,GRM2,KDR,ACHE,FLT3
NCT04740580,NCT00056225,NCT01439555,NCT03062449 |
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA2,IGF1R,SRC,MET,EGFR,CYP19A1,KDR,AXL,CDK1,CA14
NCT00908791,NCT02427581,NCT00986609 |
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
AKR1C3,OR51E2,SLCO1B1,F2,XDH,GRIA2,SLCO1B3,ALOX12,CDK1,GRM1,TSHR,AURKB,NPSR1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
GRM1,SNCA,NOX4,SLC1A1,OR51E2,CYP19A1,CYP3A4,MET,FABP5,CDK1,FABP3,AURKB,FFAR1
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
SRC,F2,GRIN1,NFKB1,GRIN2B
NCT04764383,NCT03266965,NCT01381354,NCT00638196,NCT02220933,NCT02220244,NCT02936037 |
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NR1I2,GRM8,FABP3,FFAR1,ABCG2,SLC1A1,GSTP1,NOX4,GRIK3,GRM5,APP,IGF1R
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
ACHE,NR1I2,AKR1C3,SLCO1B1,F2,XDH,SLCO1B3,GRIK5,CDK1,TSHR,AURKB,NPSR1
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
CA2,CYP1A1,GRM8,ALOX15,F2,AURKB,XDH,SLCO1B3,GRIK3,CDK1,HCAR2,NPSR1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
ACHE,HSD17B10,NFKB1,AKR1B1,ALOX15,CYP3A4,CYP1B1,FFAR4,HCAR2,FABP5,FLT3,GRIK1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
KDR,FLT3,CDK1,GSTP1,EGFR,AXL,ALOX5,IGF1R,MET
NCT00033722,NCT00402883 |
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
EGFR,MET,KDR
NCT00606502,NCT00609518,NCT00806819,NCT01165021,NCT03370159,NCT05096663,NCT03166254,NCT01194453 |
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
GRM8,CYP19A1,ALOX15,SLCO1B1,F2,SLCO1B3,NOX4,CDK1,MET,AURKB,NPSR1
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
KDR,CA2,CYP19A1,LMNA,GRIK3,CYP1B1,HCAR2,TSHR,CSNK2A3,FABP5,MET
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CA2,CYP1A1,CYP3A4,GRM2,GRIK3,CYP1A2,HCAR2,GRIK1,GRIA1,MET,AURKB
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
GRM1,LMNA,GRIK3,CYP19A1,EGFR,XDH,GRIA1,GRM5,AXL,FFAR1
|
Hypertension Stage 1Disease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71.1 |
NCT02825901
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
CYP19A1
|
FilariasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F66 |
ALOX5
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE
|
Mental/behavioural/neurodevelopmental disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20-6E8Z |
GRM2
|
Epidermal dysplasiasDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK90 |
SRC
|
Inborn purine/pyrimidine/nucleotide metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C55 |
XDH
|
LeiomyosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B58 |
SRC
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NFKB1
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
TP53
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
Metastatic digestive system neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D8Y |
SRC
|
Digestive organ benign neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E92 |
KDR
|
Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F2
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
TP53
|
Bone/articular cartilage neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7B |
FLT3
|
Fragile X chromosomeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD55 |
GRM5
|
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
SRC
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
IGF1R
|
EncephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E47 |
XDH
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
TP53
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
Mineral deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5K |
XDH
|
Inborn metabolism deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5C59 |
CA14
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Autonomic nervous system disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87 |
SNCA
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
Synovial sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5A |
SRC
|
Metastatic malignant neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E09 |
AXL
|
Multiple structural anomalies syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F |
IGF1R
|
Metastatic liver/bile duct neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D80 |
TP53
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
TP53
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
GRM5
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
EGFR
|
Human immunodeficiency virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C60-1C62 |
FLT3
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
FLT3
|
Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F2
|
Alpha-1-antitrypsin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C5A |
GRIN2B
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
Transplanted organ/tissueDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QB63 |
FLT3
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
TSHR
|
Lip/oral cavity/pharynx neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6E |
TP53
|
AmyloidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5D00 |
APP
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Carcinoid syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B10 |
ALOX5
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
CYP19A1
|
MastocytosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21 |
FLT3
|
Extraocular muscle disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C82 |
IGF1R
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
NFKB1
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
FLT3
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F2
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
AKR1C3
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
ACHE
|
Skin sensation disturbanceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME65 |
GRM5
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
FLT3
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
EGFR
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
TP53
|
Diagnostic imagingDisease Category: NADisease ICD-11 Code: N.A. |
APP
|
Dystrophic epidermolysis bullosaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EC32 |
APP
|
Tonus and reflex abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB47 |
GRM5
|
Phakomatoses/hamartoneoplastic syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2D |
FLT3
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
FLT3
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR
|
Arteries/arterioles disorderDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD52 |
MAPK1
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
GRIK1
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2
|
Desmoid tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7C |
APP
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
MET
|
Congenital aplastic anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A70.0 |
NCT01720147
|
Infantile spasmsDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A62.0 |
NCT01828437
|
Harmful effects of drugs, medicaments or biological substances, not elsewhere classifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE60 |
NCT02908581
|
Malignant neoplasms of retroperitoneumDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C50 |
NCT01188876
|
Other specified disorders of carbohydrate absorption or transportDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C61.Y |
NCT02291458
|
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT03359239
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
NCT05452772
|
Malignant lymphoma, not elsewhere classifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33.5 |
NCT02702492
|
Sezary syndromeDisease Category: X.Extension CodesDisease ICD-11 Code: XH8HN3 |
NCT01134341
|
Infectious gastroenteritis or colitis without specification of infectious agentDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A40.Z |
NCT00133406
|
Inflammatory carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C62 |
NCT00986609
|
Carcinomas of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.0 |
NCT03162562
|
Carcinoma of male breastDisease Category: X.Extension CodesDisease ICD-11 Code: XH5KW8 |
NCT01042535
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT02730949
|
Chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
NCT03861416
|
Chronic kidney disease, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.Z |
NCT00136188
|
Asymptomatic stenosis of intracranial or extracranial arteryDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD55 |
NCT00000599
|
BeriberiDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5A.0 |
NCT01864057
|
Flare or flashDisease Category: X.Extension CodesDisease ICD-11 Code: XE03F |
NCT01140646
|
Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT01436266
|
Noninfectious erosive or ulcerative disorders of oral mucosaDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01.1 |
NCT04989049
|
Preterm newborn, unspecifiedDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA21.4Z |
NCT00218946
|
Atherosclerotic chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD40.Z |
NCT00804843
|
Cerebrovascular diseases, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B2Z |
NCT00000599
|
Periodontal diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0C |
NCT05042024
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT05378919
|
Anterior uveitisDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A96 |
NCT01900431
|
CraniopharyngiomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1AZ2 |
NCT01419067
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT03718507
|
Circadian rhythm sleep disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A60-7A65 |
NCT01468038
|
Ependymoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1511 |
NCT02125786
|
Acute myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41 |
NCT02929888
|
Movement disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A07-8A0Z |
NCT01908452
|
Acute ischaemic heart disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA4Z |
NCT00855257
|
Mycosis fungoidesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B01 |
NCT01134341
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT01953536
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT05276895
|
Pulmonary alveolar proteinosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB04.31 |
NCT03887169
|
Malignant neoplasms of gallbladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C13 |
NCT01766219
|
Diabetic lactic acidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A22.1 |
NCT00143702
|
Acute viral hepatitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50 |
NCT00108589
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
NCT00300365
|
Oral mucositisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01 |
NCT03581773
|
Alcoholic hepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB94.1 |
NCT00200746
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NCT04249336
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT00133419
|
Mild hyperemesis gravidarumDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA60.0 |
NCT00861523
|
Aortic valve stenosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB70 |
NCT02109614
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
NCT00000324
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT00480207
|
Abdominal pelvic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD81 |
NCT00694564
|
SarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2C35 |
NCT02484391
|
Argininosuccinic aciduriaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.A0 |
NCT00345605
|
Intermediate hyperglycaemia, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.Z |
NCT02756117
|
Lichen planusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA91 |
NCT01375101
|
Symptoms and signs involving cognition, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.Z |
NCT03493178
|
Obstruction of bile ductDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC10.02 |
NCT03418935
|
MelasmaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60.1 |
NCT01603446
|
Huntington diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01.10 |
NCT04478734
|
Gastro-oesophageal reflux diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA22 |
NCT02226484
|
Other specified syndromes with multiple structural anomalies, not of environmental originDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F.1Y |
NCT00446147
|
Human immunodeficiency virus type 1Disease Category: X.Extension CodesDisease ICD-11 Code: XN8LD |
NCT01426438
|
CholangiocarcinomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH7M15 |
NCT01766219
|
Melanoma of skin, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30.Z |
NCT02129075
|
Rhabdomyosarcoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0GA1 |
NCT01871766
|
MyelofibrosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A22 |
NCT05025488
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
NCT04855266
|
Anaplastic large cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1LC0 |
NCT01134341
|
Intracranial injury, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.Z |
NCT03228524
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
NCT00763633
|
Recurrent pregnancy lossDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA33 |
NCT01976676
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
NCT03090048
|
Hereditary sensory and autonomic neuropathy type IDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C21.0 |
NCT01733407
|
Beta thalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50.2 |
NCT00006136
|
Parasitic infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D0Y-1G2Z |
NCT00396500
|
Galactose-1-phosphate uridyltransferase deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C51.40 |
NCT03580122
|
Retinopathy of prematurityDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71.3 |
NCT01238471
|
Vitamin A deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55 |
NCT00128557
|
Malignant neoplasms of other or unspecified parts of mouthDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B66 |
NCT05456022
|
Relapsing-remitting multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40.0 |
NCT03387046
|
Respiratory failureDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB41 |
NCT01985685
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
SLCO1B3
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
FABP4
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CYP1A1
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
FABP4
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
HCAR2
|
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
FABP4
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
Plant-Targeted Human Disease Network
>> Targets derived from weak experimental activities
