Collective Molecular Activities of the Plant: Colchicum Brachyphyllum
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PLANiTS DNA barcode
Taxonomic Information
Plant ID: NPO24146
Plant Latin Name: Colchicum Brachyphyllum
Taxonomy Genus: Colchicum
Taxonomy Family: Colchicaceae
Plant External Links:
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Compounds Summary
Overview of Ingredients
11 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
11 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
11 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC66678
Ingredient ID: NPC53146
Ingredient ID: NPC474129
Ingredient ID: NPC3906
Ingredient ID: NPC329837
Ingredient ID: NPC286790
Ingredient ID: NPC264145
Ingredient ID: NPC226941
Ingredient ID: NPC225710
Ingredient ID: NPC189782
Ingredient ID: NPC156654
Classification of Human Proteins Collectively Targeted by the Plant
*The classification criteria of Drug Transporter (DTP), CYP450 are referred to DrugMap. Other molecular targets in CMAUP are classified as therapeutic targets.
.
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 2 | CYP2D6 | Cytochrome P450 2D6 | P10635 | CHEMBL289 |
| Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
| Therapeutic Target | Lyase | CA14 | Carbonic anhydrase XIV | Q9ULX7 | CHEMBL3510 |
| Therapeutic Target | Lysine demethylase | KDM4E | Lysine-specific demethylase 4D-like | B2RXH2 | CHEMBL1293226 |
| Therapeutic Target | Secreted protein | THPO | Thrombopoietin | P40225 | CHEMBL1293256 |
| Drug Transporter | SLC superfamily of solute carriers | SLC22A3 | Solute carrier family 22 member 3 | O75751 | CHEMBL2073673 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Transcription factor | PAX8 | Paired box protein Pax-8 | Q06710 | CHEMBL2362980 |
| Therapeutic Target | Transferase | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Q11130 | CHEMBL3596077 |
| Therapeutic Target | Unclassified protein | GMNN | Geminin | O75496 | CHEMBL1293278 |
Clinical Trials Summary
Overview
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 84 | |
Clinical trial details
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT04916522 | The COlchicine HypERtENsion Trial | hypertension | Colchicine (NPC226941) | NP level |
| NCT04355143 | Colchicine to Reduce Cardiac Injury in COVID-19 (COLHEART-19) | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT03131583 | The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout | gout | Colchicine (NPC226941) | NP level |
| NCT04997551 | Double Blind Randomized Clinical Trial of Use of Colchicine Added to Standard Treatment in Hospitalized With Covid-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT00128427 | Study of Colchicine to Prevent the Postpericardiotomy Syndrome | Postpericardiotomy Syndrome | Colchicine (NPC226941) | NP level |
| NCT00128414 | Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) | pericarditis | Colchicine (NPC226941) | NP level |
| NCT00506883 | MPC-004 for the Treatment of an Acute Gout Flare | gout | Colchicine (NPC226941) | NP level |
| NCT04500665 | Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine | chronic kidney disease | Colchicine (NPC226941) | NP level |
| NCT05159219 | Colchicine for the Prevention of Vascular Events After an Acute Intracerebral Hemorrhage | intracranial hemorrhage | Colchicine (NPC226941) | NP level |
| NCT01994226 | Colchicine Or Naproxen Treatment for ACute gouT | gout | Colchicine (NPC226941) | NP level |
| NCT00819585 | A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study) | gout | Colchicine (NPC226941) | NP level |
| NCT01985425 | Colchicine For Prevention of Perioperative Atrial Fibrillation in Patients Undergoing Thoracic Surgery Pilot Study | atrial fibrillation | Colchicine (NPC226941) | NP level |
| NCT02060552 | Immune Molecular and Inflammatory Cytokines Dysfunction Analysis in Gout Patients With Different Urate Levels | gout | Colchicine (NPC226941) | NP level |
| NCT04392141 | Colchicine Plus Phenolic Monoterpenes to Treat COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04008316 | Efficacy of Colchicine to Prevent Skin Relapses in Adult's IgA Vasculitis | vasculitis | Colchicine (NPC226941) | NP level |
| NCT04420624 | COLchicine to Prevent Sympathetic Denervation After an Acute Myocardial Infarction | myocardial infarction | Colchicine (NPC226941) | NP level |
| NCT01005121 | Colchicine for Diabetic Nephropathy | diabetic nephropathy | Colchicine (NPC226941) | NP level |
| NCT04359095 | Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in Colombia | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT02330796 | Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout | gout | Colchicine (NPC226941) | NP level |
| NCT04264260 | Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment | cholangiocarcinoma | Colchicine (NPC226941) | NP level |
| NCT00700297 | Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's Disease | Behcet's syndrome | Colchicine (NPC226941) | NP level |
| NCT00370760 | Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR) | proliferative vitreoretinopathy | Colchicine (NPC226941) | NP level |
| NCT01399008 | Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients | gout | Colchicine (NPC226941) | NP level |
| NCT02442921 | Colchicine for Diabetic Nephropathy Trial | diabetic nephropathy | Colchicine (NPC226941) | NP level |
| NCT02162303 | Colchicine in Vascular Inflammation Assessed With PET Imaging | vascular disease | Colchicine (NPC226941) | NP level |
| NCT04363437 | COlchicine in Moderate-severe Hospitalized Patients Before ARDS to Treat COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04160117 | Impact of Short-course Colchicine Versus Placebo After Pulmonary Vein Isolation (IMPROVE-PVI Pilot) | atrial fibrillation | Colchicine (NPC226941) | NP level |
| NCT04724629 | Survival TRial Using CytoKines in COVID-19 (STRUCK Trial) | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04539873 | Impact of Colchicine in Hospitalized Colombian Patients With COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT03015831 | Effect of Low Dose ColchiciNe on the InciDence of POAF | atrial fibrillation | Colchicine (NPC226941) | NP level |
| NCT03048825 | Colchicine and Spironolactone in Patients With MI / SYNERGY Stent Registry | Non-ST Elevation Myocardial Infarction;ST Elevation Myocardial Infarction | Colchicine (NPC226941) | NP level |
| NCT05503225 | Colchicine Use in Intracranial Atherosclerotic Disease | atherosclerosis | Colchicine (NPC226941) | NP level |
| NCT02139046 | Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout | gout | Colchicine (NPC226941) | NP level |
| NCT03693781 | Colchicine for Amyotrophic Lateral Sclerosis | amyotrophic lateral sclerosis | Colchicine (NPC226941) | NP level |
| NCT04867226 | Effectiveness of Colchicine Among Patients With COVID-19 Infection | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT00004748 | Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis | primary biliary cirrhosis | Colchicine (NPC226941) | NP level |
| NCT02366091 | Inflammation and Coronary Endothelial Function | coronary artery disease | Colchicine (NPC226941) | NP level |
| NCT04472611 | Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT05175274 | Colchicine Use for Primary Prevention of Coronary Artery Disease | coronary artery disease | Colchicine (NPC226941) | NP level |
| NCT04381936 | Randomised Evaluation of COVID-19 Therapy | severe acute respiratory syndrome | Colchicine (NPC226941) | NP level |
| NCT00754819 | Targeting Inflammation in Acute Coronary Syndrome Using Colchicine | acute coronary syndrome | Colchicine (NPC226941) | NP level |
| NCT05118737 | Adding Colchicine to Tocilizumab in Patients With Severe COVID-19 Pneumonia. | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04130204 | Topical Application to Relieve Gout: Efficacy Trial & Safety (TARGETS) | gout | Colchicine (NPC226941) | NP level |
| NCT04603690 | Oral Curcumin, Quercetin and Vitamin D3 Supplements for Mild to Moderate Symptoms of COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04705987 | Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure | heart failure | Colchicine (NPC226941) | NP level |
| NCT05472337 | Effect of Colchicine on Coronary Reperfusion in Patients With Acute Coronary Syndrome | acute coronary syndrome | Colchicine (NPC226941) | NP level |
| NCT02063997 | Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patients | gout | Colchicine (NPC226941) | NP level |
| NCT00004368 | Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis | cirrhosis of liver | Colchicine (NPC226941) | NP level |
| NCT02602028 | The Comparison of the Efficacy of Once and Twice Daily Colchicine Dosage in Pediatric Patients With FMF | familial Mediterranean fever | Colchicine (NPC226941) | NP level |
| NCT05279690 | Pilot Trial of Colchicine in Urothelial Cancer and Other Solid Tumors | neoplasm;urogenital neoplasm | Colchicine (NPC226941) | NP level |
| NCT02176460 | Colchicine for Symptom and Inflammation in Knee Osteoarthritis | osteoarthritis | Colchicine (NPC226941) | NP level |
| NCT03575572 | Colchicine in Postoperative Fontan Patients | heart disease | Colchicine (NPC226941) | NP level |
| NCT00723268 | Evaluation of Therapeutic Effect of 0.5 mg Colchicine and 5 mg Prednisolone on Oral Aphthae | aphthous ulcer | Colchicine (NPC226941) | NP level |
| NCT04756128 | Impact of Colchicine and Low-dose Naltrexone on COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT01075906 | Pharmacokinetics Study of Colchicine in Familial Mediterranean Fever (FMF) Patients | familial Mediterranean fever | Colchicine (NPC226941) | NP level |
| NCT04516941 | CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19 | COVID-19;severe acute respiratory syndrome | Colchicine (NPC226941) | NP level |
| NCT04322682 | Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04326790 | The GReek Study in the Effects of Colchicine in Covid-19 cOmplications Prevention | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04416334 | PREEMPTIVE THERAPY WITH COLCHICINE IN PATIENTS OLDER THAN 60 YEARS WITH HIGH RISK OF SEVERE PNEUMONIAE DUE TO CORONAVIRUS | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT00128453 | Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences | pericarditis | Colchicine (NPC226941) | NP level |
| NCT00840489 | Efficacy of Long-term Ribavirin in Non-responders With Chronic Hepatitis C and Advanced Fibrosis | chronic hepatitis C virus infection | Colchicine (NPC226941) | NP level |
| NCT04367168 | Colchicine in Patients With Mild and Severe Coronavirus Disease | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT05324423 | To Evaluate Drug Interactions Between XNW3009, Febuxostat, and Colchicine in Patients With Gout | gout | Colchicine (NPC226941) | NP level |
| NCT05250596 | COLchicine On-admission to Reduce Inflammation in Acute Coronary Syndrome (COLOR-ACS) | acute coronary syndrome | Colchicine (NPC226941) | NP level |
| NCT04328480 | The ECLA PHRI COLCOVID Trial. Effects of Colchicine on Moderate/High-risk Hospitalized COVID-19 Patients. | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04492358 | Treatment for Moderate/Severe COVID-19 in a Fragile and Vulnerable Population, Admitted to a Geriatric Hospital Unit or in a Transicional Care Center | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT00000577 | Asthma Clinical Research Network (ACRN) | asthma;lung disease | Colchicine (NPC226941) | NP level |
| NCT01481233 | Oral Colchicine in Men With Castrate Resistant Prostate Cancer | prostate cancer | Colchicine (NPC226941) | NP level |
| NCT05151614 | Adjuvant Use Of Colchicine With The Standard Therapy In Moderate And Severe Corona Virus Disease-19 Infection | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04324463 | Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial | COVID-19;severe acute respiratory syndrome | Colchicine (NPC226941) | NP level |
| NCT03021343 | Effect of Colchicine on the Incidence of Atrial Fibrillation in Open Heart Surgery Patients | cardiac arrhythmia | Colchicine (NPC226941) | NP level |
| NCT05459974 | Use of Colchicine to Decrease Atrial Fibrillation Recurrence After Ablation | atrial fibrillation | Colchicine (NPC226941) | NP level |
| NCT04762771 | Colchicine for the Treatment of Cardiac Injury in Hospitalized Patients With COVID-19 (COLHEART-19) | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT03905759 | Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABG | atrial fibrillation | Colchicine (NPC226941) | NP level |
| NCT04870424 | Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement | atrial fibrillation | Colchicine (NPC226941) | NP level |
| NCT04360980 | The Effects of Standard Protocol With or Without Colchicine in Covid-19 Infection | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04350320 | Trial to Study the Benefit of Colchicine in Patients With COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT01755949 | Colchicine and CRP in Atrial Fibrillation and AF Ablation | atrial fibrillation | Colchicine (NPC226941) | NP level |
| NCT04375202 | Colchicine in COVID-19: a Pilot Study | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT04322565 | Colchicine Counteracting Inflammation in COVID-19 Pneumonia | coronavirus infectious disease;viral pneumonia | Colchicine (NPC226941) | NP level |
| NCT04667780 | Study to Investigate the Treatment Effect of Colchicine in Patients With COVID-19 | COVID-19 | Colchicine (NPC226941) | NP level |
| NCT03156816 | COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction | myocardial infarction | Colchicine (NPC226941) | NP level |
| NCT02500641 | Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout | gout | Colchicine (NPC226941) | NP level |
| NCT02582190 | COlchicine for the Prevention of Post Electrical Cardioversion Recurrence of AF | atrial fibrillation | Colchicine (NPC226941) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT02582190,NCT04160117,NCT03905759,NCT01985425,NCT05459974,NCT03015831,NCT01755949,NCT04870424
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
HSD17B10,THPO,PAX8,TUBB6,GMNN,SLC22A3,TDP1,LMNA
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HSD17B10,FUT7,PAX8,CA2,GMNN,TDP1,CA14
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
FUT7,PAX8,CA2,TUBB6,SLC22A3,CA14,LMNA
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
FUT7,PAX8,GMNN,SLC22A3,TDP1,LMNA
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
FUT7,CA2,GMNN,TDP1
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
PAX8,TUBB6,GMNN,LMNA
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
THPO,CA2,CA14,KDM4E
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CA2,TUBB6,GMNN,LMNA
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
THPO
NCT04420624,NCT03156816 |
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04324463,NCT04381936,NCT04516941
|
Acute ischaemic heart disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA4Z |
NCT05472337,NCT00754819,NCT05250596
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
FUT7,CA2,CA14
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
GMNN,PAX8,GMNN
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
CA2,LMNA,TUBB6
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
GMNN,THPO,CYP2D6
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
PAX8,CA2,CYP2D6
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B10,FUT7,GMNN
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
GMNN,FUT7,CA14
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
FUT7,THPO,TUBB6
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04603690,NCT04724629,NCT04359095,NCT04472611,NCT04363437,NCT04360980,NCT04324463,NCT05118737,NCT04392141,NCT04539873,NCT04516941,NCT04350320,NCT04997551,NCT04416334,NCT04492358,NCT04667780,NCT04322682,NCT04762771,NCT04328480,NCT04867226,NCT04375202,NCT04355143,NCT05151614,NCT04367168,NCT04326790,NCT04756128
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
CA14,CA2
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA2,CA14
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
CA2
NCT04705987 |
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2,CYP2D6
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA14,CA2
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT02366091,NCT05175274
|
Chronic kidney disease, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.Z |
NCT02442921,NCT01005121
|
Familial Mediterranean feverDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A60.0 |
NCT02602028,NCT01075906
|
Acute pericarditisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB20 |
NCT00128414,NCT00128453
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CA2,PAX8
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
THPO,FUT7
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
GMNN,FUT7
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
NCT02330796,NCT00506883,NCT01994226,NCT04130204,NCT02060552,NCT02139046,NCT03131583,NCT02063997,NCT02500641,NCT01399008,NCT05324423,NCT00819585
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
|
Inborn metabolism deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5C59 |
CA14
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
CYP2D6
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
CA2
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
THPO
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
CA2
|
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
NCT05503225
|
Behçet diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A62 |
NCT00700297
|
VasculitisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A44 |
NCT04008316
|
Intracranial injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07 |
NCT05159219
|
CholangiocarcinomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH7M15 |
NCT04264260
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT03693781
|
Acute ST elevation myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41.0 |
NCT03048825
|
Cardiac arrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC9Z |
NCT03021343
|
VitreoretinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B78 |
NCT00370760
|
Oral aphthae or aphtha-like ulcerationDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01.10 |
NCT00723268
|
Viral pneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.1 |
NCT04322565
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT00000577
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
NCT04322565
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Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT04500665
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Primary biliary cholangitis, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB96.1Z |
NCT00004748
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Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT00004368
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Urogenital cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C95-2C9Z |
NCT05279690
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Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT00840489
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OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT02176460
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NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT05279690
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Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
NCT03575572
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Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
NCT01481233
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Diseases of the circulatory system, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BE2Z |
NCT02162303
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AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
NCT00000577
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Postcardiotomy syndromeDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BE10 |
NCT00128427
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Acute non-ST elevation myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41.1 |
NCT03048825
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Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT04916522
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HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
GMNN
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LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
FUT7
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
GMNN
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
CA14
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
SLC22A3
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Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
FUT7
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
FUT7
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA
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Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FUT7
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Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CA2
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❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
Plant-Targeted Human Disease Network
>> Targets derived from weak experimental activities
