Plant ID: NPO24093
Plant Latin Name: Drynaria Fortunei
Taxonomy Genus: Drynaria
Taxonomy Family: Polypodiaceae
NCBI TaxonomyDB:
272675
Plant-of-the-World-Online:
n.a.
China
Ingredient ID: NPC89088
Ingredient ID: NPC88022
Ingredient ID: NPC85550
Ingredient ID: NPC70741
Ingredient ID: NPC66349
Ingredient ID: NPC65003
Ingredient ID: NPC61477
Ingredient ID: NPC60124
Ingredient ID: NPC5029
Ingredient ID: NPC48342
Ingredient ID: NPC42760
Ingredient ID: NPC39360
Ingredient ID: NPC328788
Ingredient ID: NPC324278
Ingredient ID: NPC323434
Ingredient ID: NPC323177
Ingredient ID: NPC319193
Ingredient ID: NPC316926
Ingredient ID: NPC316658
Ingredient ID: NPC311988
Ingredient ID: NPC311485
Ingredient ID: NPC307875
Ingredient ID: NPC294902
Ingredient ID: NPC293138
Ingredient ID: NPC291124
Ingredient ID: NPC290613
Ingredient ID: NPC29
Ingredient ID: NPC287349
Ingredient ID: NPC28318
Ingredient ID: NPC280717
Ingredient ID: NPC278552
Ingredient ID: NPC269751
Ingredient ID: NPC265442
Ingredient ID: NPC261619
Ingredient ID: NPC250828
Ingredient ID: NPC249045
Ingredient ID: NPC246469
Ingredient ID: NPC243959
Ingredient ID: NPC231608
Ingredient ID: NPC230301
Ingredient ID: NPC227777
Ingredient ID: NPC227542
Ingredient ID: NPC225710
Ingredient ID: NPC225703
Ingredient ID: NPC225660
Ingredient ID: NPC222084
Ingredient ID: NPC221909
Ingredient ID: NPC219876
Ingredient ID: NPC214153
Ingredient ID: NPC210003
Ingredient ID: NPC204932
Ingredient ID: NPC198743
Ingredient ID: NPC196776
Ingredient ID: NPC193067
Ingredient ID: NPC190270
Ingredient ID: NPC185689
Ingredient ID: NPC1788
Ingredient ID: NPC166885
Ingredient ID: NPC162822
Ingredient ID: NPC162685
Ingredient ID: NPC157410
Ingredient ID: NPC156655
Ingredient ID: NPC156654
Ingredient ID: NPC154409
Ingredient ID: NPC152538
Ingredient ID: NPC149006
Ingredient ID: NPC145708
Ingredient ID: NPC145347
Ingredient ID: NPC142860
Ingredient ID: NPC142753
Ingredient ID: NPC142569
Ingredient ID: NPC141078
Ingredient ID: NPC138572
Ingredient ID: NPC137816
Ingredient ID: NPC137167
Ingredient ID: NPC135602
Ingredient ID: NPC131157
Ingredient ID: NPC130760
Ingredient ID: NPC127944
Ingredient ID: NPC126029
Ingredient ID: NPC115674
Ingredient ID: NPC1075
Ingredient ID: NPC100909
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Enzyme | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | P05186 | CHEMBL5979 |
Therapeutic Target | Enzyme | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
Therapeutic Target | Lyase | CA14 | Carbonic anhydrase XIV | Q9ULX7 | CHEMBL3510 |
Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
Therapeutic Target | Lysine demethylase | KDM4E | Lysine-specific demethylase 4D-like | B2RXH2 | CHEMBL1293226 |
Therapeutic Target | Metallo protease | MMP9 | Matrix metalloproteinase 9 | P14780 | CHEMBL321 |
Therapeutic Target | Metallo protease | MMP1 | Matrix metalloproteinase-1 | P03956 | CHEMBL332 |
Therapeutic Target | Metallo protease | MMP2 | Matrix metalloproteinase-2 | P08253 | CHEMBL333 |
Therapeutic Target | Methyl-lysine/arginine binding protein | SMN1 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESRRA | Estrogen-related receptor alpha | P11474 | CHEMBL3429 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESRRB | Estrogen-related receptor beta | O95718 | CHEMBL3751 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR2 | Estrogen receptor beta | Q92731 | CHEMBL242 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | AR | Androgen Receptor | P10275 | CHEMBL1871 |
Therapeutic Target | Oxidoreductase | AOX1 | Aldehyde oxidase | Q06278 | CHEMBL3257 |
Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
Therapeutic Target | Peptide receptor (family A GPCR) | TSHR | Thyroid stimulating hormone receptor | P16473 | CHEMBL1963 |
Therapeutic Target | Secreted protein | SHBG | Testis-specific androgen-binding protein | P04278 | CHEMBL3305 |
Therapeutic Target | Small molecule receptor (family A GPCR) | GPER1 | G-protein coupled estrogen receptor 1 | Q99527 | CHEMBL5872 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD1 | Dopamine D1 receptor | P21728 | CHEMBL2056 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
Therapeutic Target | Transferase | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Q11130 | CHEMBL3596077 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 110 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00185237 | Treatment of Hot Flushes in Asian Women With Ultra-low Dose Estradiol Patch | Hot flashes | Estradiol (NPC48342) | NP level |
NCT02847806 | Effects of Replacement Therapy With Sexual Steroid Hormones on the Insulin Sensitivity of Hypogonadal Man | hypogonadism | Estradiol (NPC48342) | NP level |
NCT03556800 | Study to Investigate the Pharmacokinetics & Safety Following One Application of 3 Different Doses 0.5,0.75,& 1.25 gm,a Transdermal Estradiol Cream (VML-0203), in Comparison to a Single Dose of EstroGel 1.25 gm to Healthy Post-menopausal Women. | menopause | Estradiol (NPC48342) | NP level |
NCT04225221 | Neurobiology of Bulimia Nervosa | bulimia nervosa | Estradiol (NPC48342) | NP level |
NCT01508858 | Influence on the Effect of an Oral Contraceptive Drug After Administration of Liraglutide in Postmenopausal Women | type 2 diabetes mellitus | Estradiol (NPC48342) | NP level |
NCT00946192 | Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes | amenorrhea | Estradiol (NPC48342) | NP level |
NCT03821415 | Effects of RP101 in Post-menopausal Women With Dry Eye Syndrome | dry eye syndrome | Estradiol (NPC48342) | NP level |
NCT00413764 | Efficacy of Tibolone Versus Transdermal E2/NETA on Sexual Function in Naturally Postmenopausal Women (P06089) | sexual dysfunction | Estradiol (NPC48342) | NP level |
NCT00870220 | Initiating Transdermal Estradiol Therapy in Turner's Syndrome | Turner syndrome | Estradiol (NPC48342) | NP level |
NCT00698035 | Vaginal Testosterone Cream vs ESTRING for Vaginal Dryness or Decreased Libido in Early Stage Breast Cancer Patients | sexual dysfunction | Estradiol (NPC48342) | NP level |
NCT01923298 | Estradiol Levels in Patients Treated With Estring | breast cancer | Estradiol (NPC48342) | NP level |
NCT02995694 | A Study Comparing Estradiol Vaginal Cream to Estrace® Cream in Females With Atrophic Vaginitis | Atrophic Vaginitis | Estradiol (NPC48342) | NP level |
NCT00864214 | A Pharmacokinetic Evaluation of Bioidentical Compounded Estrogen Cream and Natural Progesterone | menopause | Estradiol (NPC48342) | NP level |
NCT05472779 | Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections | urinary tract infection | Estradiol (NPC48342) | NP level |
NCT03751124 | Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids | uterine fibroid | Estradiol (NPC48342) | NP level |
NCT00310531 | 3-year Study of Menostar Versus Evista to Prevent Osteoporosis in Post-menopausal Women | Osteopenia | Estradiol (NPC48342) | NP level |
NCT00837616 | Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism | Premature ovarian insufficiency | Estradiol (NPC48342) | NP level |
NCT00080756 | Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease | Hereditary breast and ovarian cancer syndrome | Estradiol (NPC48342) | NP level |
NCT00251082 | Vasomotoric Symptoms Study of a 0.5 mg Estradiol and 2.5 mg Dydrogesterone Combination | menopause | Estradiol (NPC48342) | NP level |
NCT00000559 | Women's Estrogen/Progestin Lipid Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) | menopause;Myocardial Ischemia | Estradiol (NPC48342) | NP level |
NCT00732693 | Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure | Premature ovarian insufficiency | Estradiol (NPC48342) | NP level |
NCT04265053 | Human Cerebral Blood Flow Regulation | cerebral arterial disease | Estradiol (NPC48342) | NP level |
NCT00001481 | The Role of Hormones in Postpartum Mood Disorders | postpartum depression | Estradiol (NPC48342) | NP level |
NCT00303784 | Prostate Adenocarcinoma TransCutaneous Hormones | prostate cancer | Estradiol (NPC48342) | NP level |
NCT03941730 | Estradiol in Treating Patients With ER Beta Positive, Triple Negative Locally Advanced or Metastatic Breast Cancer | breast carcinoma | Estradiol (NPC48342) | NP level |
NCT03238092 | Comparison Between Testosterone and Estradiol Over the Homogenization of Follicular Cohort | infertility | Estradiol (NPC48342) | NP level |
NCT02224313 | Effect of Oral Estradiol and Progesterone Therapy on Vaginal Cytokines in Postmenopausal Women | menopause | Estradiol (NPC48342) | NP level |
NCT03204318 | SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain | pain | Estradiol (NPC48342) | NP level |
NCT01942668 | A Safety and Efficacy Study of the Combination Estradiol and Progesterone to Treat Vasomotor Symptoms | menopause | Estradiol (NPC48342) | NP level |
NCT03236662 | (-)- Epicatechin Becker Muscular Dystrophy | Becker muscular dystrophy | (-)-Epicatechin (NPC126029) | NP level |
NCT03240081 | Treating Postmenopausal Dyspareunia Where it Hurts | Dyspareunia | Estradiol (NPC48342) | NP level |
NCT00003771 | Hormone Replacement Therapy and the Risk of Breast Cancer Recurrence in Women With Previous Early Stage Breast Cancer | breast cancer | Estradiol (NPC48342) | NP level |
NCT01856868 | Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study) | Becker muscular dystrophy | (-)-Epicatechin (NPC126029) | NP level |
NCT02188745 | ER Reactivation Therapy for Breast Cancer | breast cancer | Estradiol (NPC48342) | NP level |
NCT04386304 | Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy | Becker muscular dystrophy | (+)-Epicatechin (NPC261619) | NP level |
NCT01265017 | Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes | type 1 diabetes mellitus | Estradiol (NPC48342) | NP level |
NCT01880866 | (-)-Epicatechin and Pulmonary Arterial Hypertension | pulmonary arterial hypertension | (-)-Epicatechin (NPC126029) | NP level |
NCT00184795 | Bleed Free Treatment of Menopausal Symptoms With New Ultra Low Dose Hormonal Combinations | menopause | Estradiol (NPC48342) | NP level |
NCT00140998 | Estrogen Treatment (Oral vs. Patches) in Turner Syndrome | Turner syndrome;Premature ovarian insufficiency | Estradiol (NPC48342) | NP level |
NCT00059228 | Clinical Trial of Estrogen for Postpartum Depression | postpartum depression | Estradiol (NPC48342) | NP level |
NCT02349113 | Effects of Acute Estrogen Therapy on Bone Formation | osteoporosis | Estradiol (NPC48342) | NP level |
NCT00357006 | A Definitive Estrogen Patch Study (ADEPT) | schizoaffective disorder;schizophrenia | Estradiol (NPC48342) | NP level |
NCT02660112 | (+) Epicatechin to Treat Friedreich's Ataxia | Friedreich ataxia | (+)-Epicatechin (NPC261619) | NP level |
NCT00176644 | Phase II Trial of Transdermal Estradiol for Hormone Refractory Prostate Cancer | prostate cancer | Estradiol (NPC48342) | NP level |
NCT00108849 | Vagifem Low Dose for Postmenopausal Atrophic Vaginitis Symptoms | Atrophic Vaginitis | Estradiol (NPC48342) | NP level |
NCT00220454 | Effect of Estrogen & Stress for Postmenopausal Women | aging | Estradiol (NPC48342) | NP level |
NCT01603745 | Effects of Drospirenone-ethinylestradiol and/or NOMAC-valerate Estradiol on Cardiovascular Risk in Women With Polycystic Ovary Syndrome | polycystic ovary syndrome | Estradiol (NPC48342) | NP level |
NCT02351622 | Caffeic Acid Tablets as a Second-line Therapy for ITP | autoimmune thrombocytopenic purpura | Caffeic Acid (NPC294902) | NP level |
NCT00302731 | Bioidentical 'Natural' Hormone Evaluation in Early Menopause | menopause | Estradiol (NPC48342) | NP level |
NCT00687739 | Prevention of Obesity in Women Via Estradiol Regulation | obesity | Estradiol (NPC48342) | NP level |
NCT00455962 | Effect of Race on Gonadotropin Responses | menopause | Estradiol (NPC48342) | NP level |
NCT04648917 | GASC1 Inhibitor Caffeic Acid for Squamous Esophageal Cell Cancer (ESCC) | esophageal cancer | Caffeic Acid (NPC294902) | NP level |
NCT00212342 | Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Dysmenorrhea | Dysmenorrhea | Estradiol (NPC48342) | NP level |
NCT01596010 | Investigation of 2 Different Oral Formulations of Estradiol and Norethisterone in Healthy Women | menopause | Estradiol (NPC48342) | NP level |
NCT01293747 | Pharmacokinetics of Injectable Estradiol and Progesterone Microspheres Suspension | menopause | Estradiol (NPC48342) | NP level |
NCT00775242 | Efficacy and Safety of Estradiol and Progesterone Microspheres for the Treatment of Climacteric Symptoms. | menopause | Estradiol (NPC48342) | NP level |
NCT00905723 | The Effects of Isoflavone and Estrogen in Sex Response in Climacteric Women | menopause | Estradiol (NPC48342) | NP level |
NCT00370019 | Effects of an Estrogen Replacement Therapy Skin Patch on Ovulation in Women With Premature Ovarian Failure | Premature ovarian insufficiency | Estradiol (NPC48342) | NP level |
NCT00114517 | ELITE: Early Versus Late Intervention Trial With Estradiol | atherosclerosis | Estradiol (NPC48342) | NP level |
NCT02770365 | Comparative Safety and Efficacy of Two Treatments in the Treatment of Vulvar and Vaginal Atrophy | Atrophy | Estradiol (NPC48342) | NP level |
NCT04833140 | Estrogen Administration for the Treatment of NASH in Postmenopausal Women | non-alcoholic steatohepatitis | Estradiol (NPC48342) | NP level |
NCT00391417 | Efficacy and Safety of a Topical Estradiol Gel for Treatment of Postmenopausal Symptoms | Hot flashes | Estradiol (NPC48342) | NP level |
NCT00268476 | Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy | prostate cancer | Estradiol (NPC48342) | NP level |
NCT05387577 | Coagulation and Fibrinolysis of Estradiol in Transwomen | blood coagulation disease | Estradiol (NPC48342) | NP level |
NCT02467673 | Nanoparticulate Versus Micronized Steroids Delivery for Transdermal Hormone Replacement Therapy | menopause | Estradiol (NPC48342) | NP level |
NCT01984138 | REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy | breast cancer | Estradiol (NPC48342) | NP level |
NCT02792153 | Estradiol and Fear Extinction in Anorexia Nervosa (AN) | anorexia nervosa | Estradiol (NPC48342) | NP level |
NCT01810315 | Influence of Reproductive Cycle and Menopause on HIV-1 Infection and TFV Gel Activity | HIV infection | Estradiol (NPC48342) | NP level |
NCT02330276 | Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin | prediabetes syndrome | (+)-Epicatechin (NPC261619) | NP level |
NCT00127075 | POPART'MUS: Prevention of Post Partum Relapses With Progestin and Estradiol in Multiple Sclerosis | multiple sclerosis | Estradiol (NPC48342) | NP level |
NCT03343067 | A Study to Evaluate Safety and Efficacy of Elagolix in Participants With Endometriosis With Associated Moderate to Severe Pain | endometriosis | Estradiol (NPC48342) | NP level |
NCT02656212 | Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin (Part 2) | prediabetes syndrome | (+)-Epicatechin (NPC261619) | NP level |
NCT01126801 | Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women | depressive disorder | Estradiol (NPC48342) | NP level |
NCT01690676 | Effect of an Apple Polyphenol Extract on Brachial Artery Flow-mediated Vasodilatory Function | hypertension | (+)-Epicatechin (NPC261619) | NP level |
NCT00459810 | Paclitaxel Poliglumex and Estradiol in Treating Patients With Stage IV Prostate Cancer | prostate cancer | Estradiol (NPC48342) | NP level |
NCT01083641 | Estrogen for Triple Negative Breast Cancer | breast cancer | Estradiol (NPC48342) | NP level |
NCT04192266 | Estrogen and Fear in PTSD | post-traumatic stress disorder | Estradiol (NPC48342) | NP level |
NCT04021017 | PRE-GAiN Bone Health Pilot Study | anorexia nervosa | Estradiol (NPC48342) | NP level |
NCT04597099 | Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion | polycystic ovary syndrome | Estradiol (NPC48342) | NP level |
NCT03213457 | A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Participants With Moderate to Severe Endometriosis-Associated Pain | endometriosis | Estradiol (NPC48342) | NP level |
NCT00204074 | Treatment of Menstrual Migraine With Sequential, Transdermal, 17-Beta-Estradiol. A Double-Blind, Randomised, Cross-Over Trial. | migraine disorder | Estradiol (NPC48342) | NP level |
NCT02736032 | Cryopreserved-thawed Embryo Transfer With or Without Gonadotropin Releasing Hormone Agonist | infertility | Estradiol (NPC48342) | NP level |
NCT00328497 | A Combination Study to Determine the Safety and Efficacy of Panzem NCD With Avastin in Metastatic Carcinoid Tumors | carcinoid tumor | Estradiol (NPC48342) | NP level |
NCT01779947 | Study to Evaluate the Safety and Bioequivalence of Estradiol Vaginal Inserts, 10 mcg and Vagifem® 10 mcg and Compare to Placebo | postmenopausal atrophic vaginitis | Estradiol (NPC48342) | NP level |
NCT00727129 | Study to Evaluate Divigel for the Treatment of Postmenoupausal Symptoms | menopause | Estradiol (NPC48342) | NP level |
NCT03294538 | Study to Evaluate Equivalence of Estradiol Vaginal Cream 0.01% to Estrace® Cream 0.01% in Atrophic Vaginitis | Atrophic Vaginitis | Estradiol (NPC48342) | NP level |
NCT04853069 | Oestrogen Treatment for COVID-19 Symptoms | COVID-19 | Estradiol (NPC48342) | NP level |
NCT02964377 | Plus Epicatechin Duchenne Muscular Dystrophy in Non-ambulatory Adolescents | Duchenne muscular dystrophy | (+)-Epicatechin (NPC261619) | NP level |
NCT02195986 | A Comparison of Estradiol Vaginal Cream to Estrace® Cream in 350 Postmenopausal Females With Atrophic Vaginitis | Atrophic Vaginitis | Estradiol (NPC48342) | NP level |
NCT04359329 | Estrogen Patch for COVID-19 Symptoms | COVID-19 | Estradiol (NPC48342) | NP level |
NCT01710696 | Induction of Puberty With 17-beta Estradiol in Girls With Turner Syndrome | Turner syndrome | Estradiol (NPC48342) | NP level |
NCT02238808 | A Study to See Whether Estrogen Can Slow the Growth of Some ER Positive Breast Cancers | breast cancer | Estradiol (NPC48342) | NP level |
NCT04760691 | Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW | HIV infection | Estradiol (NPC48342) | NP level |
NCT03401047 | Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome | polycystic ovary syndrome | Estradiol (NPC48342) | NP level |
NCT01301183 | Effects of Anorexia Nervosa on Peak Bone Mass | anorexia nervosa | Estradiol (NPC48342) | NP level |
NCT01973816 | MEdical Versus SUrgical Treatments of Rectal Endometriosis | endometriosis | Estradiol (NPC48342) | NP level |
NCT00324259 | Study of Physiological and High Dose Estradiol in the Treatment of Hormone Receptor Positive Metastatic Breast Cancer | breast neoplasm | Estradiol (NPC48342) | NP level |
NCT03837015 | Estrogen, Probiotics and Vaginal Health to Prevent HIV Infection in ACB Women | HIV-1 infection | Estradiol (NPC48342) | NP level |
NCT02668796 | To Study Generic Estradiol 10 mcg Vaginal Tablets in the Treatment of Vulvar and Vaginal Atrophy in Post Menopausal Women. | Atrophic Vaginitis | Estradiol (NPC48342) | NP level |
NCT01400776 | Safety & Efficacy WC3011 (Estradiol Vaginal Cream) in the Treatment of Vulvovaginal Atrophy in Postmenopausal Women | Atrophic Vaginitis | Estradiol (NPC48342) | NP level |
NCT00167648 | Neoadjuvant Estradiol or Androgen Deprivation in Clinically Localized Prostate Cancer | prostate carcinoma | Estradiol (NPC48342) | NP level |
NCT00044837 | Hormone Replacement Therapy and Anti-HIV Drugs in HIV-Infected, Postmenopausal Women | HIV infection | Estradiol (NPC48342) | NP level |
NCT03654274 | SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain | endometriosis | Estradiol (NPC48342) | NP level |
NCT01477632 | Bioavailability of Three Oral Formulations for Hormone Replacement Therapy in Postmenopausal Women | menopause | Estradiol (NPC48342) | NP level |
NCT00066157 | Alzheimer's Disease: Therapeutic Potential of Estrogen | Alzheimer disease | Estradiol (NPC48342) | NP level |
NCT00206557 | The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study | schizoaffective disorder;schizophrenia | Estradiol (NPC48342) | NP level |
NCT00160316 | Endometrial Safety Study of a 0.5 mg Estradiol and 2.5 mg Dydrogesterone Combination | menopause | Estradiol (NPC48342) | NP level |
NCT02516202 | The Vaginal Health Trial | Atrophic Vaginitis;menopause;Dyspareunia | Estradiol (NPC48342) | NP level |
NCT00661531 | Estrogen in Postmenopausal Women With ER Positive Metastatic Breast Cancer After Failure of Sequential Endocrine Therapy | breast carcinoma | Estradiol (NPC48342) | NP level |
NCT03332303 | Study to Evaluate the Equivalence of Estradiol Vaginal Cream to Reference Standard in the Treatment of Vaginal Atrophy | Atrophic Vaginitis | Estradiol (NPC48342) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
ESR1,ESR2,MTOR,AR,AOX1
NCT00176644,NCT00268476,NCT00459810,NCT00303784 |
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
BLM,CYP3A4,FUT7,AR,MMP9,SNCA,MMP1,CA7
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
BLM,CA14,FUT7,CA2,MMP9,SNCA,MMP1
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
BLM,FUT7,TSHR,MMP2,MMP9,MMP1,ALPL
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
BLM,F2,ESRRB,ALPL,CA2,MMP9,MMP1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
ESRRB,FUT7,CYP3A4,NFKB1,MMP9,DRD1,HSD17B10
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
BLM,MMP2,ESR2,MMP9,MMP1,LMNA
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
MMP9,F2,FUT7,TSHR,MMP9,MMP1
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
BLM,F2,TSHR,MMP9,MMP1,CA7
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CA14,ESRRB,ESR2,MMP9,KDM4E,CA2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
BLM,F2,TSHR,MMP9,MMP1,CA7
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
BLM,AR,TSHR,CA2,AOX1,LMNA
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
ESRRB,FUT7,MMP2,GPER1,ESR1,AOX1
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
CA2,MMP1,MMP9,ESRRA,NFKB1
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
ESR1
NCT03213457,NCT03343067,NCT03654274,NCT01973816 |
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
BLM,F2,MMP9,MMP1,DRD1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
BLM,MMP9,MMP1,MMP9,MMP1
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
BLM,CYP3A4,MMP9,MMP1,CA2
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
BLM,FUT7,ESR1,MMP9,MMP1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MMP1,MTOR,MMP2,MMP9
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
ESRRB,CYP3A4,ESRRA,NFKB1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
MMP2,MMP1,MMP9,ESR1
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NFKB1,ESR1,F2
NCT00127075 |
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
ESRRA,DRD1
NCT00357006,NCT00206557 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
MTOR,DRD1
NCT01690676,NCT01880866 |
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
MMP9
ALPL,MMP9,MMP1 |
Premature ovarian failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30.6 |
NCT00732693,NCT00370019,NCT00837616,NCT00140998
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FUT7
NCT03401047,NCT04597099,NCT01603745 |
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
BLM,MMP2,MMP9,MMP1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
CA2,ESRRB,SNCA,LMNA
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2,ESR1,AR
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
NCT03238092,NCT02736032 |
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1,MMP2,AR
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
MMP1,MTOR,MMP2
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
NCT02516202,NCT03240081 |
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ESRRA,ESR2,ESRRB
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
ESRRB,NFKB1,ESRRA
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
ESR2,SNCA
NCT00066157 |
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
F2,NFKB1
NCT01508858 |
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
MMP2,MMP9,MTOR
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
NCT00661531,NCT03941730 |
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
ESRRB,F2,ESRRA
|
Becker muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.0 |
NCT03236662,NCT04386304,NCT01856868
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT01810315,NCT00044837,NCT04760691
|
Anorexia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B80 |
NCT01301183,NCT02792153,NCT04021017
|
Turner syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD50.0 |
NCT00870220,NCT00140998,NCT01710696
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
ALPL,MMP9,MMP1
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
ALPL,MMP9,MMP2
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
F2,MMP9,MMP1
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
CA14,F2,ESRRB
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
BLM,MMP9,MMP1
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
ALPL,CA7,MMP1
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
MMP2,ESRRB,LMNA
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP3A4,CA2,ESRRA
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
ESRRB,ESRRA
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
ESRRA,ESRRB
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
AR,ESR1
|
Skin diseaseDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA00-EM0Z |
ESRRA,ESRRB
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SNCA,DRD1
|
Contact dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK00-EK0Z |
ESRRB,ESRRA
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
AR,NFKB1
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
MMP9,F2
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
CA2,AR
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
AR,ESR2
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ESR2,ESR1
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA2,CA14
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NFKB1,ESR1
|
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
SMN1,SMN2
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
GPER1,MTOR
|
Eyelid inflammatory disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A02 |
ESRRB,ESRRA
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AR,F2
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1,AR
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
ESR2,NFKB1
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
AR,NFKB1
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR2,ESR1
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
AR,F2
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
MTOR
NCT03204318 |
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04853069,NCT04359329
|
Intermediate hyperglycaemia, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.Z |
NCT02330276,NCT02656212
|
Mental or behavioural disorders associated with pregnancy, childbirth or the puerperium, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20 |
NCT00059228,NCT00001481
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
NCT00357006,NCT00206557
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
MMP9
NCT04833140 |
Flare or flashDisease Category: X.Extension CodesDisease ICD-11 Code: XE03F |
NCT00391417,NCT00185237
|
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
NCT00698035,NCT00413764
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
F2,MMP1
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
SHBG,FUT7
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
MMP9,MMP1
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
MMP9,MMP1
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ESRRB,MMP9
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
BLM,MMP9
|
MenopauseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30.0 |
NCT01942668,NCT00160316,NCT00184795,NCT00302731,NCT03556800,NCT00864214,NCT00905723,NCT02516202,NCT02224313,NCT00000559,NCT00775242,NCT00455962,NCT01596010,NCT02467673,NCT00727129,NCT01293747,NCT00251082,NCT01477632
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
MTOR,ESR1,CA14,AR,CA2,ESR2
NCT01984138,NCT02188745,NCT01083641,NCT02238808,NCT01923298,NCT00003771 |
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
CA14,ESRRB,FUT7,TDP1,TSHR,CA2,ESRRA,MMP9,MMP1,ALPL,CA7,HSD17B10
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
CA2,MMP9,ESRRA,ESR1,CA14,CYP3A4,MTOR,AOX1,ESRRB,NFKB1,GPER1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
BLM,TDP1,TSHR,AR,MMP2,ESR2,MMP1,AOX1,SMN1,HSD17B10,LMNA
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
BLM,CA14,F2,DRD1,FUT7,MMP2,SNCA,MMP1,CA2,CA7,LMNA
|
Postmenopausal atrophic vaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30.2 |
NCT01400776,NCT02195986,NCT02995694,NCT01779947,NCT02770365,NCT03294538,NCT03332303,NCT02516202,NCT00108849,NCT02668796
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
ESRRB,FUT7,TDP1,TSHR,CA2,ESRRA,ESR1,MMP9,MMP1,ALPL
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
DRD1,FUT7,TDP1,MMP9,SNCA,MMP1,AOX1,CA7,SMN1,LMNA
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
BLM,CA14,F2,FUT7,MMP2,ESRRA,SNCA,MMP1,DRD1,SMN1
|
HydrocephalusDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D64 |
MTOR
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
TSHR
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
AR
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
F2
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
DRD1
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
ESR2
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2
|
Autonomic nervous system disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87 |
SNCA
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
NFKB1
|
Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F2
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
ESR2
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
MTOR
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
MMP9
|
Hypo-osmolality/hyponatraemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C72 |
AR
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
F2
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
ALPL
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Arteries/arterioles disorderDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD52 |
MTOR
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ESR1
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
MTOR
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
ESR2
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
F2
|
Genetic prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E02 |
ALPL
|
Testicular dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A81 |
AR
|
Pleural mesotheliomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26 |
MTOR
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
MTOR
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
TSHR
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
AR
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
DRD1
|
Muscle disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB32-FB3Z |
AR
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
MTOR
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
MTOR
|
Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F2
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
CYP3A4
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F2
|
Degenerative high myopiaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B76 |
ESRRA
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
DRD1
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
MTOR
|
AbortionDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA00 |
DRD1
|
Alcoholic liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB94 |
AR
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
MTOR
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
MTOR
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
F2
|
AlopeciaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED70 |
AR
|
Tic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A05 |
DRD1
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
MTOR
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
DRD1
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
F2
|
Inborn metabolism deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5C59 |
CA14
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
MMP9
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
MTOR
|
Vitamin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55-5B5F |
AOX1
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
CA2
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
MTOR
|
Parasitic infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D0Y-1G2Z |
ALPL
|
Mammary tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Z |
AR
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
MMP2
|
LymphangioleiomyomatosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB07 |
MTOR
|
Bulimia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B81 |
NCT04225221
|
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
NCT00114517
|
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT02964377
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
NCT04192266
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT01265017
|
DysmenorrhoeaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34.3 |
NCT00212342
|
Migraine disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SD10 |
NCT00204074
|
Asymptomatic stenosis of intracranial or extracranial arteryDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD55 |
NCT04265053
|
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT00000559
|
Friedreich ataxiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03.10 |
NCT02660112
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT00220454
|
Uterine fibroidDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E66 |
NCT03751124
|
AmenorrhoeaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20.0 |
NCT00946192
|
Hereditary breast and ovarian cancer syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C65 |
NCT00080756
|
Neuroendocrine tumour, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH8DS0 |
NCT00328497
|
Immune thrombocytopenic purpuraDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64.10 |
NCT02351622
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
NCT00687739
|
Gonadotropin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A61.2 |
NCT02847806
|
OsteoporosisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83.1 |
NCT02349113
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Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
NCT04648917
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Diseases of the visual system, unspecifiedDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9E1Z |
NCT03821415
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Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
NCT05472779
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OsteopeniaDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83.0 |
NCT00310531
|
Human immunodeficiency virus type 1Disease Category: X.Extension CodesDisease ICD-11 Code: XN8LD |
NCT03837015
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT01126801
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Blood-forming organ diseaseDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3C0Z |
NCT05387577
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Malignant neoplasms of prostate, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.Z |
NCT00167648
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Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT00324259
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Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
TSHR
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Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
TSHR
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
NFKB1
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
MMP9
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
MMP1
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
MMP9
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
MMP9
|