CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Marrubium Vulgare

Example Image

PLANiTS DNA barcode

Click for details-----ITS

GCAGAACGACGAACACGTTTCATCACTCGGGATTCGTGGCGAGGGGGCAACCTCCCGTCGTGTTCCCCTCCCGCACGATGCGCGCTGAAGTGTGCATTGTGTGGGCTAACGAACCCCCGGCGCGGCATGCGCCAAGGAAAACTCATAGAAGCGTCCACCTCCCATCGACCCGTTCGCGGTGAGCGAGGGGGGAGAGGACGTCTCTCGAATGTCATAACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCGAAGCCACTAGGCCAAGGGCACGTCTGCCTGGGCGTCACGCATCGCGTCGCCCCCCGATCCCTCTCGCATAGGGCGAACGGCTGTTGGGGGGCGGACATTGGCCTCCCGTGCACGATAGTGTGCGGCTGGCCTAAATGAGATCCCGCGGCGACTCACGTCACGACCAGTGGTGGTTGAACTCTCAACTCGCGTGCTGTCGTGGTGAACTGCGTCGTCTGTCGGGCATCATTTTGAGACCCAATGGTGCGACCCATTCGCGCTTTCGACCGCGACCCC

Click for details-----ITS1

Click for details-----ITS2

ATCGCGTCGCCCCCCGATCCCTCTCGCATAGGGCGAACGGCTGTTGGGGGGCGGACATTGGCCTCCCGTGCACGATAGTGTGCGGCTGGCCTAAATGAGATCCCGCGGCGACTCACGTCACGACCAGTGGTGGTTGAACTCTCAACTCGCGTGCTGTCGTGGTGAACTGCGTCGTCTGTCGGGCATCATTTTGAGACCCAATGGTGCGACCCATTCGCGCTTTCGACCGCGACCCC

Taxonomic Information

Plant ID: NPO23264
Plant Latin Name: Marrubium Vulgare
Taxonomy Genus: Marrubium
Taxonomy Family: Lamiaceae

Plant External Links:

NCBI TaxonomyDB: 41230
Plant-of-the-World-Online: 449990-1

Used in Medicines

Country/Region:

Israel; Italy; Turkmenistan; Mexico; India; Lebanon; China; Chile; Argentina; Spain; Bulgaria

Traditional Medicine System:

Indian Folk; TCM; Siddha

Medicinal Functions:

Antidiarrhoeal; Antidote; Antiflatulent; Antiseptic; Antispasmodic; Appetizer; Cholagogue; Diaphoretic; Digestive; Diuretic; Emmenagogue; Expectorant; Hepatic; Stimulant; TB; Tonic

Geographical Distribution

Brazil; Afghanistan; Italy; Peru; Canada; Lebanon; Nepal; France; Netherlands; Ireland; Argentina; Bolivia; Venezuela; Ecuador; Turkmenistan; Uzbekistan; Israel; Belarus; Iran; Algeria; Turkey; Cape Verde; Guatemala; China; Chile; Belgium; Germany; Iraq; Kazakhstan; Spain; Ukraine; Georgia; Libya; Denmark; Poland; New Caledonia; United States; Morocco; Sweden; Saudi Arabia; Switzerland; New Zealand; Russia; Bulgaria; Pakistan; Romania; Albania; Portugal; Mexico; Tunisia; Uruguay; India; United Kingdom; Austria; Colombia; Greece; Hungary; Cyprus

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

54 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

27 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)