Plant ID: NPO22526
Plant Latin Name: Justicia Secunda
Taxonomy Genus: Justicia
Taxonomy Family: Acanthaceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC97444
Ingredient ID: NPC85799
Ingredient ID: NPC76128
Ingredient ID: NPC69266
Ingredient ID: NPC65530
Ingredient ID: NPC58628
Ingredient ID: NPC53168
Ingredient ID: NPC50898
Ingredient ID: NPC5029
Ingredient ID: NPC48367
Ingredient ID: NPC3845
Ingredient ID: NPC3357
Ingredient ID: NPC312929
Ingredient ID: NPC30432
Ingredient ID: NPC303422
Ingredient ID: NPC29874
Ingredient ID: NPC293378
Ingredient ID: NPC289346
Ingredient ID: NPC288089
Ingredient ID: NPC282923
Ingredient ID: NPC276222
Ingredient ID: NPC273557
Ingredient ID: NPC272865
Ingredient ID: NPC271385
Ingredient ID: NPC26080
Ingredient ID: NPC254847
Ingredient ID: NPC254603
Ingredient ID: NPC252169
Ingredient ID: NPC248949
Ingredient ID: NPC248573
Ingredient ID: NPC245584
Ingredient ID: NPC242712
Ingredient ID: NPC235784
Ingredient ID: NPC22697
Ingredient ID: NPC226906
Ingredient ID: NPC225710
Ingredient ID: NPC22563
Ingredient ID: NPC223004
Ingredient ID: NPC221090
Ingredient ID: NPC219876
Ingredient ID: NPC20791
Ingredient ID: NPC203468
Ingredient ID: NPC192916
Ingredient ID: NPC19256
Ingredient ID: NPC191011
Ingredient ID: NPC190457
Ingredient ID: NPC190078
Ingredient ID: NPC189142
Ingredient ID: NPC179950
Ingredient ID: NPC178851
Ingredient ID: NPC176740
Ingredient ID: NPC173637
Ingredient ID: NPC161571
Ingredient ID: NPC157517
Ingredient ID: NPC156654
Ingredient ID: NPC142153
Ingredient ID: NPC139508
Ingredient ID: NPC13674
Ingredient ID: NPC118284
Ingredient ID: NPC109879
Ingredient ID: NPC108167
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
Cytochrome P450 | Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
Therapeutic Target | Enzyme | NOX4 | NADPH oxidase 4 | Q9NPH5 | CHEMBL1250375 |
Therapeutic Target | Enzyme | ALOX12 | Arachidonate 12-lipoxygenase | P18054 | CHEMBL3687 |
Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
Therapeutic Target | Lyase | CA4 | Carbonic anhydrase IV | P22748 | CHEMBL3729 |
Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
Therapeutic Target | Lyase | CA14 | Carbonic anhydrase XIV | Q9ULX7 | CHEMBL3510 |
Therapeutic Target | Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
Therapeutic Target | Lysine demethylase | KDM4E | Lysine-specific demethylase 4D-like | B2RXH2 | CHEMBL1293226 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR2 | Estrogen receptor beta | Q92731 | CHEMBL242 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
Therapeutic Target | Oxidoreductase | PTGS2 | Cyclooxygenase-2 | P35354 | CHEMBL230 |
Therapeutic Target | Oxidoreductase | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | P14061 | CHEMBL3181 |
Therapeutic Target | Oxidoreductase | NQO2 | Quinone reductase 2 | P16083 | CHEMBL3959 |
Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
Therapeutic Target | Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Therapeutic Target | Protein Kinase | YES1 | Tyrosine-protein kinase YES | P07947 | CHEMBL2073 |
Therapeutic Target | Protein Kinase | AURKB | Serine/threonine-protein kinase Aurora-B | Q96GD4 | CHEMBL2185 |
Therapeutic Target | Protein Kinase | CDK1 | Cyclin-dependent kinase 1 | P06493 | CHEMBL308 |
Therapeutic Target | Protein Kinase | FLT3 | Tyrosine-protein kinase receptor FLT3 | P36888 | CHEMBL1974 |
Therapeutic Target | Protein Kinase | MET | Hepatocyte growth factor receptor | P08581 | CHEMBL3717 |
Therapeutic Target | Protein Kinase | KDR | Vascular endothelial growth factor receptor 2 | P35968 | CHEMBL279 |
Therapeutic Target | Protein Kinase | AXL | Tyrosine-protein kinase receptor UFO | P30530 | CHEMBL4895 |
Therapeutic Target | Protein Kinase | CSNK2A1 | Casein kinase II alpha | P68400 | CHEMBL3629 |
Therapeutic Target | Protein Kinase | IGF1R | Insulin-like growth factor I receptor | P08069 | CHEMBL1957 |
Therapeutic Target | Protein Kinase | PIM1 | Serine/threonine-protein kinase PIM1 | P11309 | CHEMBL2147 |
Therapeutic Target | Protein Kinase | MKNK2 | MAP kinase signal-integrating kinase 2 | Q9HBH9 | CHEMBL4204 |
Therapeutic Target | Secreted protein | THPO | Thrombopoietin | P40225 | CHEMBL1293256 |
Therapeutic Target | Secreted protein | TTR | Transthyretin | P02766 | CHEMBL3194 |
Therapeutic Target | Serine protease | DPP4 | Dipeptidyl peptidase IV | P27487 | CHEMBL284 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Threonine protease | PSMB1 | Proteasome component C5 | P20618 | CHEMBL4208 |
Therapeutic Target | Transferase | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Q11130 | CHEMBL3596077 |
Therapeutic Target | Transferase | PIK3CA | PI3-kinase p110-alpha subunit | P42336 | CHEMBL4005 |
Therapeutic Target | Transferase | PIK3CB | PI3-kinase p110-beta subunit | P42338 | CHEMBL3145 |
Therapeutic Target | Transient receptor potential channel | TRPA1 | Transient receptor potential cation channel subfamily A member 1 | O75762 | CHEMBL6007 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 85 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients | prostate cancer | Rutin (NPC176740) | NP level |
NCT02433925 | Resveratrol's Effects on Inflammation and Oxidative Stress in Chronic Kidney Disease | chronic kidney disease | Resveratrol (NPC161571) | NP level |
NCT00098969 | UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants | neoplasm | Resveratrol (NPC161571) | NP level |
NCT01492114 | Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults. | inflammation | Resveratrol (NPC161571) | NP level |
NCT03095105 | Pharmacokinetic Profile of BIA 6-512 in Healthy Elderly Subjects Versus Healthy Young Subjects | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT02612259 | A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity | obesity | Tryptophan (NPC203468) | NP level |
NCT01191216 | 1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors | neoplasm | Tryptophan (NPC203468) | NP level |
NCT03093389 | Tolerability and Steady-state Pharmacokinetics of BIA 6-512 | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT02261844 | Resveratrol and Human Hepatocyte Function in Cancer | liver cancer | Resveratrol (NPC161571) | NP level |
NCT02409537 | Effects of Dietary Antioxidants to Prevent Cardiovascular Disease | Hypercholesterolemia | Resveratrol (NPC161571) | NP level |
NCT04867252 | Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome | polycystic ovary syndrome | Resveratrol (NPC161571) | NP level |
NCT04851821 | The Effectiveness of Phytotherapy in SARS-COV2(COVID-19) | COVID-19 | Quercetin (NPC20791) | NP level |
NCT01708278 | Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
NCT00249951 | Alkaline Citrate Treatment to Lower the Risk of Nephrocalcinosis in Preterm Infants | Nephrocalcinosis | Citric Acid (NPC293378) | NP level |
NCT01012349 | Efficacy and Safety Clinical Trial of the Combination of Acetylsalicylic Acid, Sodium Bicarbonate and Citric Acid, Produced by Geolab Pharmaceutical Industries Ltd., Compared to Acetylsalicylic Acid (Aspirin ® - Bayer) in Patients With Episodic Tension-type Headache. | Tension-type headache | Citric Acid (NPC293378) | NP level |
NCT04449198 | Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1 | type 1 diabetes mellitus | Resveratrol (NPC161571) | NP level |
NCT00256334 | Resveratrol for Patients With Colon Cancer | malignant colon neoplasm | Resveratrol (NPC161571) | NP level |
NCT01421160 | Regulating Urine pH Levels to Alleviate Chronic Joint Pain | osteoarthritis | Citric Acid (NPC293378) | NP level |
NCT01438320 | Q-Trial in Patients With Hepatitis C | chronic hepatitis C virus infection | Quercetin (NPC20791) | NP level |
NCT01126229 | Resveratrol for Improved Performance in the Elderly | memory impairment | Resveratrol (NPC161571) | NP level |
NCT05456022 | Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line | mouth neoplasm | Quercetin (NPC20791) | NP level |
NCT03446625 | Resveratrol as a Preventive Treatment of OHSS | infertility | Resveratrol (NPC161571) | NP level |
NCT02226484 | Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? | gastroesophageal reflux disease | Quercetin (NPC20791) | NP level |
NCT02848131 | Senescence in Chronic Kidney Disease | chronic kidney disease | Quercetin (NPC20791) | NP level |
NCT02245932 | Resveratrol In Chronic Obstructive Pulmonary Disease (COPD) Patients (CARMENS-trial) | chronic obstructive pulmonary disease | Resveratrol (NPC161571) | NP level |
NCT01042535 | Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast Cancer | male breast carcinoma | Tryptophan (NPC203468) | NP level |
NCT01677611 | Effects of Resveratrol in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Resveratrol (NPC161571) | NP level |
NCT00567931 | 1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery | neoplasm | Tryptophan (NPC203468) | NP level |
NCT00000324 | Tryptophan and Behavior Therapy for Cocaine Abuse - 1 | cocaine dependence | Tryptophan (NPC203468) | NP level |
NCT01602068 | Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL | cataract | Citric Acid (NPC293378) | NP level |
NCT05062486 | A Study to Evaluate the Safety and Efficacy of RQC for AMD | age-related macular degeneration | Resveratrol (NPC161571);Quercetin (NPC20791) | NP level |
NCT01912820 | Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery | prostate adenocarcinoma | Quercetin (NPC20791) | NP level |
NCT01348204 | Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators | cystic fibrosis | Quercetin (NPC20791) | NP level |
NCT04622865 | Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19 | COVID-19 | Isoquercetin (NPC179950) | NP level |
NCT01504854 | Resveratrol for Alzheimer's Disease | Alzheimer disease | Resveratrol (NPC161571) | NP level |
NCT02336633 | Resveratrol and Huntington Disease | Huntington disease | Resveratrol (NPC161571) | NP level |
NCT04536090 | Study of Isoquercetin (IQC-950AN) Plus Standard of Care Versus Standard of Care Only for the Treatment of COVID-19 | COVID-19 | Isoquercetin (NPC179950) | NP level |
NCT04907253 | Quercetin in Coronary Artery By-pass Surgery | coronary artery disease | Quercetin (NPC20791) | NP level |
NCT05276895 | Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis | osteoarthritis | Quercetin (NPC20791) | NP level |
NCT02552888 | Nitrite, Isoquercetin and Endothelial Dysfunction (NICE) Trial | chronic kidney disease | Isoquercetin (NPC179950) | NP level |
NCT02314208 | Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 | Spastic paraplegia | Resveratrol (NPC161571) | NP level |
NCT03095092 | Effect of Food on BIA 6-512 (Trans-resveratrol) | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT01842399 | Resveratrol and Cardiovascular Health in the Elderly | hypertension | Resveratrol (NPC161571) | NP level |
NCT01962116 | Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU | Renal insufficiency | Citric Acid (NPC293378) | NP level |
NCT02549924 | Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Resveratrol (NPC161571) | NP level |
NCT03097211 | Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT01914081 | Resveratrol: A Potential Anti- Remodeling Agent in Heart Failure, From Bench to Bedside | dilated cardiomyopathy | Resveratrol (NPC161571) | NP level |
NCT04733534 | An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer | childhood cancer | Quercetin (NPC20791) | NP level |
NCT01564381 | Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women | cardiovascular disease | Resveratrol (NPC161571) | NP level |
NCT02030977 | The Effects of Resveratrol Supplement on Biochemical Factors and Hepatic Fibrosis in Patients With Nonalcoholic Steatohepatitis | non-alcoholic fatty liver disease | Resveratrol (NPC161571) | NP level |
NCT01321151 | Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers | concussion | Resveratrol (NPC161571) | NP level |
NCT02062190 | Resveratrol, Cardiovascular Risk Markers And Cognitive Performance In Patients With Schizophrenia | schizophrenia | Resveratrol (NPC161571) | NP level |
NCT04853199 | Quercetin In The Treatment Of SARS-COV 2 | COVID-19 | Quercetin (NPC20791) | NP level |
NCT02618824 | Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery | congenital heart disease | Tryptophan (NPC203468) | NP level |
NCT03091868 | Pharmacokinetics of Rising Single-doses of BIA 6-512 and Their Effect on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT04400890 | Randomized Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol, a Plant Polyphenol, for COVID-19 | COVID-19 | Resveratrol (NPC161571) | NP level |
NCT04542993 | Can SARS-CoV-2 Viral Load and COVID-19 Disease Severity be Reduced by Resveratrol-assisted Zinc Therapy | COVID-19;severe acute respiratory syndrome | Resveratrol (NPC161571) | NP level |
NCT02067975 | Tryptophan MRI in People With Schizophrenia and Healthy Controls | schizophrenia | Tryptophan (NPC203468) | NP level |
NCT03091543 | Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT03743636 | Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease | peripheral arterial disease | Resveratrol (NPC161571) | NP level |
NCT01375101 | Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus | oral lichen planus | Quercetin (NPC20791) | NP level |
NCT01754779 | Treatment for Calcium Phosphate Kidney Stone Disease | nephrolithiasis | Citric Acid (NPC293378) | NP level |
NCT01720147 | Quercetin in Children With Fanconi Anemia; a Pilot Study | Fanconi anemia | Quercetin (NPC20791) | NP level |
NCT04514510 | Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease | sickle cell anemia | Isoquercetin (NPC179950) | NP level |
NCT00433576 | Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery | colorectal adenocarcinoma;malignant colon neoplasm;rectum cancer | Resveratrol (NPC161571) | NP level |
NCT04474626 | Isoquercetin in Sickle Cell Anemia | sickle cell anemia | Isoquercetin (NPC179950) | NP level |
NCT02905799 | Resveratrol in Knee Osteoarthritis | osteoarthritis | Resveratrol (NPC161571) | NP level |
NCT03989271 | Biological Effects of Quercetin in COPD | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
NCT00654667 | Mechanisms of Metabolic Regulation of Resveratrol on Humans With Metabolic Syndrome | insulin resistance | Resveratrol (NPC161571) | NP level |
NCT03943459 | Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease | coronary artery disease | Quercetin (NPC20791) | NP level |
NCT02114892 | Effect of Resveratrol Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion | metabolic syndrome | Resveratrol (NPC161571) | NP level |
NCT03933163 | Micronised Resveratrol as a Treatment for Friedreich Ataxia | Friedreich ataxia | Resveratrol (NPC161571) | NP level |
NCT04946383 | Safety and Effectivness of Quercetin & Dasatinib on Epigenetic Aging | aging | Quercetin (NPC20791) | NP level |
NCT02523274 | Resveratrol and Exercise to Treat Functional Limitations in Late Life | aging | Resveratrol (NPC161571) | NP level |
NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Quercetin (NPC20791);Resveratrol (NPC161571) | NP level |
NCT03094156 | Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics | Parkinson disease | Resveratrol (NPC161571) | NP level |
NCT02219906 | Resveratrol in Metabolic Syndrome: Effect on Platelet Hyper-reactivity and HDL Lipid Peroxidation | metabolic syndrome | Resveratrol (NPC161571) | NP level |
NCT03253913 | Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial | lymphangioleiomyomatosis | Resveratrol (NPC161571) | NP level |
NCT02130440 | Evaluation of the Beneficial Effects of a Nasal Spray of Resveratrol in Children With Seasonal Allergic Rhinitis | seasonal allergic rhinitis | Resveratrol (NPC161571) | NP level |
NCT01339884 | A Study of Resveratrol as Treatment for Friedreich Ataxia | Friedreich ataxia | Resveratrol (NPC161571) | NP level |
NCT01839344 | Effects of Quercetin on Blood Sugar and Blood Vessel Function in Type 2 Diabetes. | type 2 diabetes mellitus | Quercetin (NPC20791) | NP level |
NCT02446795 | Isoquercetin as an Adjunct Therapy in Patients With Kidney Cancer Receiving First-line Sunitinib: a Phase I/II Trial | renal cell carcinoma | Isoquercetin (NPC179950) | NP level |
NCT02704494 | Resveratrol's Effects in Diabetic Nephropathy | diabetic nephropathy | Resveratrol (NPC161571) | NP level |
NCT04733651 | Study to Investigate the Clinical Efficacy of Isoquercetin in Patients With COVID-19 | COVID-19 | Isoquercetin (NPC179950) | NP level |
NCT05422885 | Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease | aging | Quercetin (NPC20791) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
EGFR,FLT3,KDM1A,KDR,ALOX5,CDK1,MET,AXL,IGF1R
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
IGF1R,SRC,AKR1B1,AURKB,NOX4,CYP19A1,CA12,CA4,CDK1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
SRC,HSD17B1,NQO2,DPP4,CA2,CA4,ACHE,PTGS2,LMNA
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CYP3A4,AKR1B1,HSD17B1,AURKB,CA9,CA2,CDK1,CYP1A2,TTR
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
PTGS2,KDR,MET,FLT3,ACHE,ESR2,PTGS1
NCT01504854 |
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
TP53,DPP4,SRC,PIK3CA,CDK1,AURKB,KDM1A,FLT3
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
ALOX5,CYP1B1,NOX4,CA12,DPP4,MET,XDH,CA7
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
CYP1A1,NPSR1,AURKB,CA9,CA2,CDK1,XDH,ALOX15
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
FUT7,CDK1,THPO,AURKB,CA9,CA12,ESR1,TRPA1
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP1A2,TTR,CA12,CA2,CYP1A1,CYP3A4,AURKB,MET
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
PIM1,TP53,AURKB,KDM1A,SRC,AXL,FLT3
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ACHE,PIK3CB,IGF1R,AKR1B1,PTGS2,PTGS1,ALOX5
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
KDR,IGF1R,MKNK2,EGFR,CSNK2A1,MET
NCT02261844 |
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04542993,NCT04851821,NCT04733651,NCT04536090,NCT04622865,NCT04400890,NCT04853199
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
NPSR1,NOX4,AURKB,CYP19A1,MET,CDK1,ALOX15
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
FUT7,THPO,CYP1B1,NOX4,DPP4,ESR1,TRPA1
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
PIK3CA,AURKB,ESR1,PIK3CB,ESR2
NCT01705652 |
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
PTGS1,PTGS2,SRC,KDR,MET
NCT01564381 |
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
MET,SRC,TP53,ESR1,KDR,EGFR
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
PTGS2,DPP4,PTGS1
NCT01677611,NCT02549924,NCT01839344 |
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
AKR1B1,PTGS2,PTGS1,ABCG2,CA2,ALOX5
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
FUT7,AKR1B1,NOX4,DPP4,FLT3,TRPA1
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
NPSR1,AURKB,NOX4,CA9,TRPA1,PTGS2
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
CYP19A1,DPP4,MET,ACHE,PTGS2,AXL
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
HSD17B1,AURKB,CA9,CA12,CDK1,XDH
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
NPSR1,AURKB,NOX4,ACHE,CDK1,ALOX15
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
TP53,EGFR,KDR,AXL,KDM1A
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
PTGS1,PTGS2
NCT02905799,NCT01421160,NCT05276895 |
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
KDR,CA9,MET,EGFR
NCT02446795 |
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
XDH,IGF1R
NCT02433925,NCT02848131,NCT02552888 |
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
MET,CA2,ACHE,CA4,AKR1B1
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
KDR,AXL,IGF1R,SRC,FLT3
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
KDR,TP53,MET,SRC,FLT3
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
CYP1A1,NPSR1,NOX4,CA9,MET
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
IGF1R,FUT7,ABCG2,NOX4,TTR
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
AXL,CYP19A1,EGFR,XDH,LMNA
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
EGFR,SRC,IGF1R,TP53
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
AKR1B1,AURKB,KDR,DPP4
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
ALOX5,PTGS2,PTGS1,CYP3A4
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
MKNK2,CA9,EGFR,KDM1A
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
THPO,PTGS1,DPP4,PTGS2
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2,PTGS1,CA4,CA12
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
KDR,EGFR,MET,TP53
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
AXL,EGFR,TP53,SRC
|
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
SRC,TP53,KDR,FLT3
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
FLT3,PTGS2,EGFR,KDR
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
TRPA1,AKR1B1,CYP19A1,PTGS1
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
PTGS2,PTGS1,CYP19A1,ESR1
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
KDR,TP53,EGFR,MET
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA12,CA4,CA2,CA14
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
PIK3CB,KDR,EGFR,MET
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
SRC,PTGS2,ALOX5,PTGS1
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ESR1,ESR2,PTGS2,PTGS1
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
NOX4,TTR,ALOX15
NCT01912820 |
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
MET,PTGS2,FLT3,AXL
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
KDM1A,PTGS1,EGFR,CYP3A4,IGF1R,CSNK2A1,PIM1,PIK3CA,MET,CA2,AURKB,CA9,MKNK2,YES1,POLB,TP53,AXL,NQO2,CA12,ALOX5,ESR1,CDK1,CA4,PIK3CB,PTGS2,XDH,CA14,FLT3,SRC,KDR
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
PTGS2,ESR1,PTGS1
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
IGF1R,ALOX5,ESR1
|
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
FLT3,SRC,KDM1A
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
ALOX5,CDK1,EGFR
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
ALOX5,FLT3,DPP4
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
PTGS2,ESR2,PTGS1
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
KDR,MET,EGFR
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
KDR,EGFR,MET
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
TP53,DPP4,MET
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
KDR,MET,SRC
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
AKR1B1
NCT02067975,NCT02062190 |
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
CA4,PTGS2,ALOX5
|
NADisease Category: NADisease ICD-11 Code: NA |
MET,NOX4
NCT01492114 |
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4
NCT02219906,NCT02114892 |
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT01191216,NCT00567931,NCT00098969
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT04946383,NCT02523274,NCT05422885
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT02245932,NCT03989271,NCT01708278
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12,CDK1,TRPA1
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
ABCG2,CA4,CA14
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
CYP1A1,YES1,ACHE
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1,PTGS2,ABCG2
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
MET,ACHE,AXL
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
HSD17B10,THPO,CSNK2A2,NOX4,CSNK2A1,RECQL,CA12,PSMB1,EGFR,CDK1,SRC,AKR1B1,TRPA1,TDP1,LMNA,AXL,ESR2,PSMB5,AURKB,CA9,KDM1A,MET,ACHE,TP53,KDR
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
PTGS1,FUT7,ALOX5,CYP1B1,NPSR1,CA7,CA14,TTR,ALOX15,ABCG2,PIM1,RECQL,DPP4,PTGS2,POLB,CA2,TRPA1,LMNA,AXL,CYP2C19,AURKB,CA9,MET,ACHE,XDH
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HSD17B10,PTGS1,FUT7,NPSR1,CA7,CA14,ALOX15,DPP4,YES1,PTGS2,POLB,AKR1B1,CA2,TRPA1,TDP1,PSMB5,AURKB,CYP19A1,CA9,KDM1A,MET,TP53,XDH
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
PTGS1,KDR,FUT7,ALOX5,CSNK2A2,FLT3,CA7,ALOX15,PIM1,RECQL,CA12,DPP4,EGFR,SRC,TRPA1,TDP1,LMNA,AXL,AURKB,CA9,MET,CDK1,XDH
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
PTGS1,KDR,FUT7,ALOX5,NPSR1,PIK3CB,NOX4,CA14,TTR,ABCG2,CA12,DPP4,ALOX12,CA4,AKR1B1,TRPA1,MET,ACHE,CDK1,XDH
|
Gastrointestinal stromal tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5B |
SRC,KDR
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ESR2
NCT02130440 |
Joint painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME82 |
PTGS2,PTGS1
|
Inflammatory spondyloarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA92 |
PTGS2,PTGS1
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR1,ESR2
|
Spinal painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84 |
PTGS2,PTGS1
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
MET,EGFR
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
CDK1,FLT3
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
FLT3,SRC
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
ESR1,DPP4
|
Reactive arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA11 |
PTGS2,PTGS1
|
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
SRC,IGF1R
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
TP53,SRC
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
XDH,ALOX5
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
SRC,ESR1
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2,NQO2
|
Otitis mediaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA80-AB0Z |
PTGS2,PTGS1
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
PTGS2,PTGS1
|
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
TP53,SRC
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
PTGS2,PTGS1
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
ESR1,CA2
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
ALOX5,KDR
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
EGFR,SRC
|
Inherited coagulation factor deficiencyDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B14 |
PTGS1,PTGS2
|
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
ALOX5,FLT3
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
TP53,SRC
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR,ESR2
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
PTGS1,PTGS2
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1,FLT3
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
NCT03446625 |
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
KDR,MET
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
ESR2,CYP19A1
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
CA2,XDH
|
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
SRC,KDR
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
PIK3CA
NCT00455416 |
Urinary system diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC2Z |
PTGS1,PTGS2
|
CardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43 |
TTR
NCT01914081 |
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
NCT01602068 |
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
PTGS1
NOX4 |
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT04514510,NCT04474626
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT03943459,NCT04907253
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT00256334,NCT00433576
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FUT7
NCT04867252 |
Friedreich ataxiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03.10 |
NCT03933163,NCT01339884
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
CYP1A1,CDK1
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE,AXL
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
AURKB,ABCG2
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
TRPA1,DPP4
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CYP1A1,CA9
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
PTGS1,NOX4
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
SRC,MKNK2,PIK3CA,AXL,CYP19A1,CA14,ESR2,NQO2,CDK1,CA2,MET,CA9,IGF1R,CA12,KDR,EGFR,ESR1,PIK3CB,CA4
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
FUT7,CSNK2A3,ALOX5,PIK3CB,NOX4,CYP1A2,ALOX15,CSNK2A1,CA12,ALOX12,YES1,ESR1,CA2,TDP1,PSMB5,CA9,MET,TP53,XDH
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
PTGS1,CSNK2A3,ALOX5,NOX4,CSNK2A1,ALOX12,CA4,CDK1,SRC,AKR1B1,TRPA1,LMNA,IGF1R,ESR2,AURKB,CA9,TP53
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ALOX5,XDH,AURKB,CYP19A1,CA9,MET,ACHE,TRPA1,FUT7,ALOX5,AURKB,CA9,TRPA1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
AURKB,NOX4,CYP19A1,CA12,CA9,CA4,CDK1,SRC,CYP19A1,AURKB,CA9,CA12,CDK1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B10,FUT7,CYP1B1,FLT3,ALOX15,DPP4,PSMB1,AKR1B1,TRPA1,CYP3A4,CA9,ACHE,PSMB5
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
KDR,CSNK2A3,LMNA,CYP1B1,CYP19A1,CA9,CA12,DPP4,CA2,MET,PTGS1,PTGS2
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
FUT7,CYP3A4,AURKB,NOX4,CYP19A1,CA12,DPP4,CA9,MET,CA4,CDK1,CA7
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
PTGS1,PTGS2,ACHE,SRC
NCT03094156,NCT03093389,NCT03091543,NCT03097211,NCT03091868,NCT03095105,NCT03095092 |
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
THPO,NPSR1,AURKB,CA9,CA12,ACHE,CDK1,TRPA1,XDH,CA7,TTR
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
IGF1R,PTGS1,PIK3CA,FLT3,MET,EGFR,TP53,MKNK2,PIK3CB,KDR
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
PTGS1,FUT7,NOX4,CA14,TTR,CA4,CA2,MET,ACHE,XDH
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CA7,NPSR1,HSD17B1,AURKB,CA12,ALOX12,CA9,CDK1,TRPA1,XDH
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CYP1A1,CYP2C19,ESR2,THPO,PIK3CB,KDM4E,CA2,ACHE,CA14,ALOX15
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AKR1B1
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
TP53
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
TP53
|
MastocytosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21 |
FLT3
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
Transplanted organ/tissueDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QB63 |
FLT3
|
FilariasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F66 |
ALOX5
|
AmyloidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5D00 |
TTR
|
LeiomyosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B58 |
SRC
|
Carcinoid syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B10 |
ALOX5
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TP53
|
Metastatic liver/bile duct neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D80 |
TP53
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
ESR2
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
TP53
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
PTGS1
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
FLT3
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
EGFR
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Metastatic malignant neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E09 |
AXL
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Multiple structural anomalies syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F |
IGF1R
|
Eye anterior segment structural developmental anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA11 |
PTGS1
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ESR1
|
Digestive organ benign neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E92 |
KDR
|
Knee osteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
PTGS2
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE
|
Ataxic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03 |
PTGS1
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
Synovial sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5A |
SRC
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
ABCG2
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
TP53
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
EncephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E47 |
XDH
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
Phakomatoses/hamartoneoplastic syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2D |
FLT3
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
ALOX5
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
CYP3A4
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
MET
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
EGFR
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB9Z |
MET
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
XDH
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
PTGS1
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE
|
Human immunodeficiency virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C60-1C62 |
FLT3
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
EGFR
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
TRPA1
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
PTGS1
|
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
MET
|
Epidermal dysplasiasDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK90 |
SRC
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
Mineral deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5K |
XDH
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
THPO
|
Metastatic digestive system neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D8Y |
SRC
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
TP53
|
Bone/articular cartilage neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7B |
FLT3
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
ESR2
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
FLT3
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
VasculitisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A44 |
PTGS1
|
Inborn metabolism deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5C59 |
CA14
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
ACHE
|
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
SRC
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
IGF1R
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
Ewing sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B52 |
KDM1A
|
Inborn purine/pyrimidine/nucleotide metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C55 |
XDH
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
IGF1R
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
FLT3
|
Lip/oral cavity/pharynx neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6E |
TP53
|
Extraocular muscle disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C82 |
IGF1R
|
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04542993
|
Congenital aplastic anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A70.0 |
NCT01720147
|
ParaplegiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB56 |
NCT02314208
|
Chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
NCT03743636
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT01842399
|
Insulin-resistance syndromesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A44 |
NCT00654667
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT04449198
|
Lichen planusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA91 |
NCT01375101
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT04733534
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT02618824
|
Gastro-oesophageal reflux diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA22 |
NCT02226484
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
NCT02030977
|
Chronic kidney disease, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61.Z |
NCT02704494
|
Age-associated cognitive declineDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.0 |
NCT01126229
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT05062486
|
Huntington diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01.10 |
NCT02336633
|
Malignant neoplasms of other or unspecified parts of mouthDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B66 |
NCT05456022
|
NephrocalcinosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB57 |
NCT00249951
|
Other specified malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NCT00433576
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
NCT02612259
|
HypercholesterolaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.0 |
NCT02409537
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT01348204
|
CholelithiasisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC11 |
NCT01754779
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT00433576
|
LymphangioleiomyomatosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB07 |
NCT03253913
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
NCT00000324
|
ConcussionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.0 |
NCT01321151
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT01438320
|
Kidney failure, unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB6Z |
NCT01962116
|
Tension-type headacheDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A81 |
NCT01012349
|
Carcinoma of male breastDisease Category: X.Extension CodesDisease ICD-11 Code: XH5KW8 |
NCT01042535
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
PTGS2
|
Non-alcoholic steatohepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92.1 |
PTGS2
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
PIM1
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
NOX4
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
CYP1A1
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
PTGS2
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
CA4
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
CA4
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
MET
|