Cardiac; Stimulant; Tonic
Turkey; Ukraine; Romania; Albania; India; Austria; China; Greece; Hungary; Bulgaria
Ingredient ID: NPC97027
Ingredient ID: NPC88539
Ingredient ID: NPC83287
Ingredient ID: NPC76372
Ingredient ID: NPC74259
Ingredient ID: NPC72260
Ingredient ID: NPC71838
Ingredient ID: NPC60450
Ingredient ID: NPC60091
Ingredient ID: NPC60056
Ingredient ID: NPC58848
Ingredient ID: NPC4949
Ingredient ID: NPC42514
Ingredient ID: NPC41586
Ingredient ID: NPC40492
Ingredient ID: NPC39358
Ingredient ID: NPC308262
Ingredient ID: NPC307150
Ingredient ID: NPC295558
Ingredient ID: NPC295110
Ingredient ID: NPC292379
Ingredient ID: NPC288816
Ingredient ID: NPC287047
Ingredient ID: NPC28024
Ingredient ID: NPC278584
Ingredient ID: NPC275772
Ingredient ID: NPC264741
Ingredient ID: NPC242031
Ingredient ID: NPC241498
Ingredient ID: NPC236993
Ingredient ID: NPC222736
Ingredient ID: NPC220217
Ingredient ID: NPC215135
Ingredient ID: NPC208193
Ingredient ID: NPC204166
Ingredient ID: NPC203375
Ingredient ID: NPC198909
Ingredient ID: NPC193893
Ingredient ID: NPC189588
Ingredient ID: NPC183529
Ingredient ID: NPC17810
Ingredient ID: NPC173555
Ingredient ID: NPC172644
Ingredient ID: NPC164268
Ingredient ID: NPC149410
Ingredient ID: NPC146414
Ingredient ID: NPC143309
Ingredient ID: NPC118715
Ingredient ID: NPC117756
Ingredient ID: NPC117445
Ingredient ID: NPC116520
Ingredient ID: NPC109571
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Enzyme | GFER | FAD-linked sulfhydryl oxidase ALR | P55789 | CHEMBL1741189 |
Therapeutic Target | Hydrolase | RAB9A | Ras-related protein Rab-9A | P51151 | CHEMBL1293294 |
Drug Transporter | Hydrolase | ATP12A | Potassium-transporting ATPase alpha chain 2 | P54707 | CHEMBL2933 |
Therapeutic Target | Methyl-lysine/arginine binding protein | SMN1 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
Therapeutic Target | Other cytosolic protein | MAPT | Microtubule-associated protein tau | P10636 | CHEMBL1293224 |
Therapeutic Target | P-type ATPase | ATP1A1 | Sodium/potassium-transporting ATPase alpha-1 chain | P05023 | CHEMBL1807 |
Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Therapeutic Target | Protein Kinase | MKNK2 | MAP kinase signal-integrating kinase 2 | Q9HBH9 | CHEMBL4204 |
Drug Transporter | SLC superfamily of solute carriers | SLCO4C1 | Solute carrier organic anion transporter family member 4C1 | Q6ZQN7 | CHEMBL2073690 |
Drug Transporter | SLC superfamily of solute carriers | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Q9Y6L6 | CHEMBL1697668 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Transcription factor | PAX8 | Paired box protein Pax-8 | Q06710 | CHEMBL2362980 |
Therapeutic Target | Transcription factor | STAT3 | Signal transducer and activator of transcription 3 | P40763 | CHEMBL4026 |
Therapeutic Target | Transcription factor | TP53 | Cellular tumor antigen p53 | P04637 | CHEMBL4096 |
Therapeutic Target | Transcription factor | KLF5 | Kruppel-like factor 5 | Q13887 | CHEMBL1293249 |
Therapeutic Target | Transporter | NPC1 | Niemann-Pick C1 protein | O15118 | CHEMBL1293277 |
Therapeutic Target | Unclassified protein | GMNN | Geminin | O75496 | CHEMBL1293278 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 73 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT01887288 | Capecitabine With Digoxin for Metastatic Breast Cancer | breast cancer | Digoxin (NPC173555) | NP level |
NCT04972396 | ALT-801 DDI Study in Healthy Volunteers | non-alcoholic steatohepatitis | Digoxin (NPC173555) | NP level |
NCT04094519 | A Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer | prostate cancer | Digoxin (NPC173555) | NP level |
NCT03136237 | A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions | hereditary angioedema | Digoxin (NPC173555) | NP level |
NCT03559868 | Inhibition of Sterile Inflammation by Digoxin | inflammation | Digoxin (NPC173555) | NP level |
NCT02888327 | A Drug-Drug Interaction Study to Evaluate the Effect of AL-794 on the Pharmacokinetics of Oseltamivir and JNJ-63623872 | influenza | Digoxin (NPC173555) | NP level |
NCT01047566 | Effect of Addition of Dronedarone to Standard Rate Control Therapy on Ventricular Rate During Persistent Atrial Fibrillation (AFRODITE) | atrial fibrillation | Digoxin (NPC173555) | NP level |
NCT01436201 | A Study of the Effect of Dulaglutide on How Body Handles Digoxin in Healthy Participants | type 2 diabetes mellitus | Digoxin (NPC173555) | NP level |
NCT05273775 | A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers | chronic hepatitis B virus infection | Digoxin (NPC173555) | NP level |
NCT03783429 | Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatients in the Netherlands | heart failure | Digoxin (NPC173555) | NP level |
NCT00000152 | Randomized Trial of Beta-Carotene and Macular Degeneration | macular degeneration | Beta Carotene (NPC17810) | NP level |
NCT01103622 | Investigate the Effect of AZD1656 on the Pharmacokinetics of Digoxin in Type 2 Diabetes Mellitus Patients | type 2 diabetes mellitus | Digoxin (NPC173555) | NP level |
NCT02906800 | Potentiation of Cisplatin-based Chemotherapy by Digoxin in Advanced Unresectable Head and Neck Cancer Patients | head and neck malignant neoplasia | Digoxin (NPC173555) | NP level |
NCT00712465 | An Interaction Study With Digoxin and AZD1305 | atrial fibrillation | Digoxin (NPC173555) | NP level |
NCT04425902 | Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults | HIV infection | Digoxin (NPC173555) | NP level |
NCT02172742 | The Effect of BIA 2-093 on the Steady-state Pharmacokinetics of Digoxin | epilepsy | Digoxin (NPC173555) | NP level |
NCT05357911 | A Study on the Effect of AB-106 on the Pharmacokinetics of Digoxin | neoplasm | Digoxin (NPC173555) | NP level |
NCT02434861 | An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects | Chemotherapy-induced nausea and vomiting | Digoxin (NPC173555) | NP level |
NCT01517399 | Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects | neoplasm | Digoxin (NPC173555) | NP level |
NCT01288742 | TMC435-TiDP16-C108 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Digoxin and Between TMC435 and Rosuvastatin | hepatitis C virus infection | Digoxin (NPC173555) | NP level |
NCT02249910 | Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy Subjects | diabetes mellitus | Digoxin (NPC173555) | NP level |
NCT00281021 | Second Line Erlotinib (Tarceva) Plus Digoxin in Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Digoxin (NPC173555) | NP level |
NCT02762123 | A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates | rheumatoid arthritis | Digoxin (NPC173555) | NP level |
NCT02626234 | A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid Tumors | neoplasm | Digoxin (NPC173555) | NP level |
NCT00000556 | Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) | atrial fibrillation | Digoxin (NPC173555) | NP level |
NCT04322552 | A Pharmacokinetic Interaction Study Between Apatinib Mesylate and Transporter Pgp Substrate Digoxin in Advanced Solid Tumor Subjects | neoplasm | Digoxin (NPC173555) | NP level |
NCT02243098 | Investigating the Influence of Semaglutide on the Pharmacokinetics of Single Doses of Atorvastatin and Digoxin in Healthy Subjects | diabetes mellitus | Digoxin (NPC173555) | NP level |
NCT01162135 | Digoxin for Recurrent Prostate Cancer | prostate cancer | Digoxin (NPC173555) | NP level |
NCT04493931 | Drug-drug Interaction Study of Gepotidacin | infection | Digoxin (NPC173555) | NP level |
NCT02797145 | Intensive Versus Conventional Digoxin Use in Patients With Heart Failure | heart failure | Digoxin (NPC173555) | NP level |
NCT00000161 | Randomized Trials of Vitamin Supplements and Eye Disease | cataract;macular degeneration | Beta Carotene (NPC17810) | NP level |
NCT02212639 | Phase II Multicentric Study of Digoxin Per os in Classic or Endemic Kaposi' s Sarcoma | Kaposi's sarcoma | Digoxin (NPC173555) | NP level |
NCT02915666 | A Clinical Trial of Patients With Melanoma | melanoma | Digoxin (NPC173555) | NP level |
NCT00782288 | Phase II Study of Digitoxin to Treat Cystic Fibrosis | cystic fibrosis | Digitoxin (NPC72260) | NP level |
NCT00904176 | Study of the Effect of Dapagliflozin on the Pharmacokinetics of Warfarin or Digoxin in Healthy Subjects | type 2 diabetes mellitus | Digoxin (NPC173555) | NP level |
NCT03197324 | Bexagliflozin Drug/Drug Interaction Study With Digoxin | diabetes mellitus | Digoxin (NPC173555) | NP level |
NCT01583036 | An Open-label, Single-centre Study Evaluating the Pharmacokinetics of Digoxin Alone and When Administered at Various Doses of Ezogabine/Retigabine in Healthy Adults. The Pharmacokinetics of Ezogabine/Retigabine and the N-acetyl Metabolite of Ezogabine/Retigabine (NAMR) Will Also be Assessed | epilepsy | Digoxin (NPC173555) | NP level |
NCT02138292 | A Phase 1B Clinical Trial of Trametinib Plus Digoxin in Patients With Unresectable or Metastatic BRAF Wild-type Melanoma | melanoma | Digoxin (NPC173555) | NP level |
NCT00650910 | Study To Examine The Effects Of Lapatinib On The Pharmacokinetics Of Digoxin In Subjects w/ ErbB2 Positive Breast Cancer | breast neoplasm | Digoxin (NPC173555) | NP level |
NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | myocardial infarction;Myocardial Ischemia | Beta Carotene (NPC17810) | NP level |
NCT03718273 | IvaBRAdine blocK of Funny Current for Heart Rate Control in permanEnt Atrial Fibrillation. (BRAKE-AF Study). | atrial fibrillation | Digoxin (NPC173555) | NP level |
NCT03928210 | Digoxin Induced Dissolution of CTC Clusters | breast cancer | Digoxin (NPC173555) | NP level |
NCT02456844 | Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients | rheumatoid arthritis | Digoxin (NPC173555) | NP level |
NCT01147718 | A Drug Interaction Study of Albiglutide and Digoxin | type 2 diabetes mellitus | Digoxin (NPC173555) | NP level |
NCT04778787 | Sodium-glucose Cotransporter Type 2 Inhibitors for Acute Cardiorenal Syndrome Prevention | congestive heart failure | Digoxin (NPC173555) | NP level |
NCT01005602 | Digoxin Dosing in Heart Failure: A Simplified Nomogram Versus Standard Care | heart failure | Digoxin (NPC173555) | NP level |
NCT01355354 | Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in Healthy Subjects | rheumatoid arthritis | Digoxin (NPC173555) | NP level |
NCT02046044 | Digoxin Versus Ivabradine in Heart Failure With Reduced Ejection Fraction | heart failure | Digoxin (NPC173555) | NP level |
NCT02775240 | Study of SHP620 (Maribavir) in Healthy Adults | cytomegalovirus infection | Digoxin (NPC173555) | NP level |
NCT01699776 | Efficacy Study of Digoxin & Ivabradine to Treat Heart Failure | heart failure | Digoxin (NPC173555) | NP level |
NCT02544815 | Digoxin Short Term Treatment Assessment Randomized Trial in AHF | heart failure | Digoxin (NPC173555) | NP level |
NCT03113071 | Safety and Activity of Digoxin With Decitabine in Adult AML and MDS | acute myeloid leukemia;myelodysplastic syndrome | Digoxin (NPC173555) | NP level |
NCT03433833 | Digoxin for Congenital Erythrocytosis Due to Up-Regulated Hypoxia Sensing | von Hippel-Lindau disease | Digoxin (NPC173555) | NP level |
NCT04887194 | PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates | neoplasm | Digoxin (NPC173555) | NP level |
NCT01765569 | A Pharmacokinetics Study to Investigate the Effect of Vemurafenib on Digoxin in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma | melanoma | Digoxin (NPC173555) | NP level |
NCT00275418 | Beta Carotene From Natural Source for Patients With Non-Active Crohn's Disease | Crohn's disease | Beta Carotene (NPC17810) | NP level |
NCT04216693 | Digoxin for Patients With Non-alcoholic Steatohepatitis (NASH) | non-alcoholic steatohepatitis | Digoxin (NPC173555) | NP level |
NCT02740712 | Pharmacokinetic Drug-Drug Interaction Study of Rucaparib | neoplasm | Digoxin (NPC173555) | NP level |
NCT01704638 | Kinetics of Fluvoxamine and Digoxin in Subjects With Different MDR1 Genotypes | depressive disorder | Digoxin (NPC173555) | NP level |
NCT04834557 | Evaluating the Effect of Digoxin and Ursodeoxycholic Acid in Patients With Rheumatoid Arthritis | rheumatoid arthritis | Digoxin (NPC173555) | NP level |
NCT05287191 | MAGNAM Trial, Magnesium Versus Amiodarone in Atrial Fribrillation in Critical Care | atrial fibrillation | Digoxin (NPC173555) | NP level |
NCT01266590 | A Study of LY2216684 and Digoxin in Healthy Subjects | major depressive disorder | Digoxin (NPC173555) | NP level |
NCT01056874 | Effect Of Maraviroc On The Pharmacokinetics Of Digoxin | HIV infection | Digoxin (NPC173555) | NP level |
NCT00390546 | Multicenter Study of Antiarrhythmic Medications for Treatment of Infants With Supraventricular Tachycardia | Supraventricular tachycardia | Digoxin (NPC173555) | NP level |
NCT00991783 | A Study to Evaluate the Effect of Fimasartan on Pharmacokinetics, and the Safety of Digoxin in Healthy Male Volunteers | essential hypertension | Digoxin (NPC173555) | NP level |
NCT02391337 | Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF) | atrial fibrillation | Digoxin (NPC173555) | NP level |
NCT02489786 | A Prospective Study of Different Digoxin Treatment Regimens in Egyptian Hospital | atrial fibrillation | Digoxin (NPC173555) | NP level |
NCT03131973 | Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin | rheumatoid arthritis | Digoxin (NPC173555) | NP level |
NCT00504413 | Role of CYP2B6, CYP3A4, and MDR1 in the Metabolic Clearance of Methadone | drug dependence | Digoxin (NPC173555) | NP level |
NCT01763931 | DIG-HIF-1 Pharmacodynamic Trial in Newly Diagnosed Operable Breast Cancer | breast cancer | Digoxin (NPC173555) | NP level |
NCT03889795 | Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors | pancreatic carcinoma | Digoxin (NPC173555) | NP level |
NCT03684772 | Topical Ionic Contra-Viral Therapy in Actinic Keratosis | actinic keratosis | Digoxin (NPC173555) | NP level |
NCT02106845 | Effect of Regorafenib on Digoxin and Rosuvastatin in Patients With Advanced Solid Malignant Tumors. | neoplasm | Digoxin (NPC173555) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
LMNA,TDP1,TP53,GMNN,FXYD2,ATP12A,GFER,PAX8,SMN1
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
ATP1A1,SLCO4C1
NCT02046044,NCT02797145,NCT01699776,NCT02544815,NCT01005602,NCT03783429 |
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
SLCO4C1,TDP1,TP53,GMNN,KLF5,ATP1A1,ATP12A,PAX8
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
LMNA,GMNN,TP53,FXYD2,KLF5,ATP1A1,MAPT,PAX8
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT01047566,NCT05287191,NCT00000556,NCT02391337,NCT00712465,NCT02489786,NCT03718273
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT02106845,NCT02740712,NCT05357911,NCT04322552,NCT01517399,NCT04887194,NCT02626234
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
LMNA,TDP1,GMNN,NPC1,KLF5,PAX8,SMN1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
PAX8,FXYD2,GMNN,MAPT,ATP1A1,GMNN,MAPT
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
SLCO4C1,GMNN,RAB9A,SLCO1B1,ATP1A1,ATP12A,SMN1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
SLCO4C1,TDP1,TP53,GMNN,ATP1A1,ATP12A
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NCT04834557,NCT03131973,NCT02456844,NCT01355354,NCT02762123
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
MKNK2,STAT3,ATP1A1,TP53
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
MKNK2
NCT01763931,NCT03928210,NCT01887288 |
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NCT01147718,NCT01436201,NCT00904176,NCT01103622
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
KLF5,PAX8,LMNA,NPC1
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
SLCO4C1,ATP12A,PAX8,SLCO1B1
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
LMNA,GMNN,RAB9A,STAT3
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
TP53,MAPT
NCT03113071 |
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
TP53,ATP1A1,STAT3
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
MKNK2,TP53,STAT3
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NCT02138292,NCT02915666,NCT01765569
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NCT03197324,NCT02243098,NCT02249910
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
SLCO4C1,ATP1A1,MAPT
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
ATP12A,GMNN,SLCO1B1
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
SLCO4C1,ATP12A,GABRA6
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
PAX8,ATP12A,SLCO4C1
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
KLF5,LMNA,ATP12A
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
ATP12A,GMNN,MAPT
|
Cardiac arrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC9Z |
ATP1A1,SLCO4C1
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
MKNK2,STAT3
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
TP53
NCT02906800 |
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
STAT3,TP53
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
STAT3,TP53
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
TP53
NCT03113071 |
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
SMN2,SMN1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
STAT3,TP53
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
NCT01162135,NCT04094519
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT00000152,NCT00000161
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
NCT04972396,NCT04216693
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT01056874,NCT04425902
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
NCT02172742,NCT01583036
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
FXYD2,GMNN
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
LMNA,RAB9A
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
SLCO4C1,SLCO1B1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
FXYD2,SLCO4C1
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
GMNN,SLCO1B1
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
FXYD2,SLCO4C1
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
ATP1A1
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
MKNK2
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
TP53
|
Lip/oral cavity/pharynx neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6E |
TP53
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
STAT3
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
MAPT
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TP53
|
Mycosis fungoidesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B01 |
STAT3
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
TP53
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
TP53
|
Supraventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81 |
ATP1A1
|
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
TP53
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
TP53
|
Immune system diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01-4B41 |
STAT3
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
STAT3
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
STAT3
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
MAPT
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
TP53
|
Acute upper respiratory infectionDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA07 |
STAT3
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
ATP1A1
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
MAPT
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
TP53
|
Dental diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA08 |
ATP1A1
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
ATP1A1
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
MAPT
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
TP53
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
ATP1A1
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
RAB9A
|
HyperhidrosisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EE00 |
ATP1A1
|
Metastatic liver/bile duct neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D80 |
TP53
|
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
TP53
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
TP53
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
TP53
|
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
STAT3
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
STAT3
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
TP53
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
NCT00991783
|
Supraventricular tachyarrhythmia, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.Z |
NCT00390546
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT00650910
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
NCT00281021
|
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT03889795
|
Hereditary angioedemaDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A00.14 |
NCT03136237
|
Congenital cytomegalovirus infectionDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA62.3 |
NCT02775240
|
Chronic hepatitis B, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.0Z |
NCT05273775
|
Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G.2Z |
NCT00504413
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT04493931
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
NCT02434861
|
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT01266590
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT00782288
|
Adrenomedullary hyperfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A75 |
NCT03433833
|
Kaposi sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B57 |
NCT02212639
|
Actinic keratosisDisease Category: X.Extension CodesDisease ICD-11 Code: XH36H6 |
NCT03684772
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
NCT00000161
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT04778787
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
NCT00275418
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT00000541
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT03559868
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT01288742
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT01704638
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
NCT02888327
|
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT00000541
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
KLF5
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
FXYD2
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
ATP12A
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
SLCO1B1
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
SLCO1B1
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
SLCO1B1
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
SLCO1B1
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
KLF5
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
KLF5
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
NPC1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
GMNN
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
FXYD2
|