Collective Molecular Activities of the Plant: Grangea Maderaspatana
Plant ID: NPO20753
Plant Latin Name: Grangea Maderaspatana
Taxonomy Genus: Grangea
Taxonomy Family: Asteraceae
Plant External Links:
NCBI TaxonomyDB:
72940
Plant-of-the-World-Online:
n.a.
Country/Region:
Thailand; IndiaTraditional Medicine System:
Indian Folk; Unani; SiddhaThailand; India
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
56 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
24 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
28 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC98777
Ingredient ID: NPC98583
Ingredient ID: NPC94583
Ingredient ID: NPC92117
Ingredient ID: NPC91409
Ingredient ID: NPC91239
Ingredient ID: NPC8651
Ingredient ID: NPC78946
Ingredient ID: NPC76128
Ingredient ID: NPC76112
Ingredient ID: NPC70622
Ingredient ID: NPC68953
Ingredient ID: NPC57380
Ingredient ID: NPC5029
Ingredient ID: NPC44260
Ingredient ID: NPC38851
Ingredient ID: NPC36959
Ingredient ID: NPC313047
Ingredient ID: NPC312929
Ingredient ID: NPC308738
Ingredient ID: NPC305843
Ingredient ID: NPC304452
Ingredient ID: NPC301384
Ingredient ID: NPC288089
Ingredient ID: NPC282923
Ingredient ID: NPC271385
Ingredient ID: NPC264145
Ingredient ID: NPC261147
Ingredient ID: NPC26080
Ingredient ID: NPC254847
Ingredient ID: NPC248949
Ingredient ID: NPC248668
Ingredient ID: NPC247364
Ingredient ID: NPC232189
Ingredient ID: NPC229036
Ingredient ID: NPC225710
Ingredient ID: NPC216752
Ingredient ID: NPC214165
Ingredient ID: NPC199875
Ingredient ID: NPC198440
Ingredient ID: NPC197087
Ingredient ID: NPC181448
Ingredient ID: NPC178851
Ingredient ID: NPC176740
Ingredient ID: NPC160512
Ingredient ID: NPC159106
Ingredient ID: NPC146973
Ingredient ID: NPC146837
Ingredient ID: NPC142811
Ingredient ID: NPC142063
Ingredient ID: NPC130315
Ingredient ID: NPC128792
Ingredient ID: NPC123953
Ingredient ID: NPC114746
Ingredient ID: NPC108455
Ingredient ID: NPC101649
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Therapeutic Target | Enzyme | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
| Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
| Therapeutic Target | Lysine demethylase | KDM4E | Lysine-specific demethylase 4D-like | B2RXH2 | CHEMBL1293226 |
| Therapeutic Target | Miscellaneous ion channel | BCL2 | Apoptosis regulator Bcl-2 | P10415 | CHEMBL4860 |
| Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
| Therapeutic Target | Oxidoreductase | PGD | 6-phosphogluconate dehydrogenase | P52209 | CHEMBL3404 |
| Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Threonine protease | PSMB5 | Proteasome Macropain subunit MB1 | P28074 | CHEMBL4662 |
| Therapeutic Target | Threonine protease | PSMB1 | Proteasome component C5 | P20618 | CHEMBL4208 |
| Therapeutic Target | Transferase | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Q11130 | CHEMBL3596077 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 52 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT03947879 | The Effect of Pharmaceutical Grade L-glutamine (Endari) on Glycemic Control in Patients With Diabetes Mellitus Type II | type 2 diabetes mellitus | Glutamine (NPC197087) | NP level |
| NCT02351323 | Novel Type 2 Diabetes Mellitus Preventive Therapies | diabetes mellitus | Glutamine (NPC197087) | NP level |
| NCT01051999 | Glutamine Supplementation in Cystic Fibrosis | cystic fibrosis | Glutamine (NPC197087) | NP level |
| NCT02961816 | Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma | lymphoma | Glutamine (NPC197087) | NP level |
| NCT01414244 | Glutamine for the Treatment of Patients With Irritable Bowel Syndrome | irritable bowel syndrome | Glutamine (NPC197087) | NP level |
| NCT04274114 | Treatment of Adults With Generalized Anxiety Disorder Using Glutamine | generalized anxiety disorder | Glutamine (NPC197087) | NP level |
| NCT01179217 | A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia | sickle cell anemia | Glutamine (NPC197087) | NP level |
| NCT02053350 | Alanyl-glutamine Supplementation of Standard Treatment for C. Difficile Infection | clostridium difficile infection | Glutamine (NPC197087) | NP level |
| NCT01983969 | Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma | lymphoma;cancer | Glutamine (NPC197087) | NP level |
| NCT02215083 | L-glutamine Supplementation to Alleviate Symptoms of Taxane-Induced Neuropathy in Patients With Breast Cancer | peripheral neuropathy | Glutamine (NPC197087) | NP level |
| NCT00645879 | Anaplerotic Therapy in Propionic Acidemia | propionic acidemia | Glutamine (NPC197087) | NP level |
| NCT01704430 | Glutamine to Improve Outcomes in Cardiac Surgery | nosocomial infection | Glutamine (NPC197087) | NP level |
| NCT01607879 | Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation | prostate cancer | Glutamine (NPC197087) | NP level |
| NCT00195013 | Randomized Placebo-Controlled Trial of Glutamine for Breast Cancer Patients With Peripheral Neuropathy | peripheral neuropathy | Glutamine (NPC197087) | NP level |
| NCT00133562 | HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition | malnutrition | Glutamine (NPC197087) | NP level |
| NCT00338221 | Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition | malnutrition | Glutamine (NPC197087) | NP level |
| NCT01952847 | Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis | cancer | Glutamine (NPC197087) | NP level |
| NCT00838149 | Effect of Glutamine on Intestinal Permeability in Crohn's Disease | Crohn's disease | Glutamine (NPC197087) | NP level |
| NCT02024191 | The Role of Glutamine for Preventing Oxaliplatin-Induced Peripheral Neuropathy | peripheral neuropathy | Glutamine (NPC197087) | NP level |
| NCT00395161 | The CRISIS Prevention Study | Sepsis | Glutamine (NPC197087) | NP level |
| NCT00125788 | L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia | Thalassemia;sickle cell anemia | Glutamine (NPC197087) | NP level |
| NCT00296621 | Effect of Oral Glutamine on Muscle Mass and Function in Duchenne Muscular Dystrophy | Duchenne muscular dystrophy | Glutamine (NPC197087) | NP level |
| NCT01478126 | Effects of Glutamine in Ischemic Heart Disease Patients Following Cardiopulmonary Bypass | coronary artery disease | Glutamine (NPC197087) | NP level |
| NCT04019769 | Glutamine Supplementation in People With Immune Dysregulation | Eczema | Glutamine (NPC197087) | NP level |
| NCT02589145 | Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype | lymphoma | Glutamine (NPC197087) | NP level |
| NCT00586209 | L-Glutamine Therapy for Sickle Cell Anemia | Thalassemia;sickle cell anemia | Glutamine (NPC197087) | NP level |
| NCT01250782 | Effectiveness of Dipeptide N (2)-L-Alanyl-L-Glutamine in Trauma ICU Patients: Pilot, Prospective, Randomized and Double Blind Study. | injury | Glutamine (NPC197087) | NP level |
| NCT00673894 | Effects of Glutamine on GLP-1 and Insulin Secretion in Man | type 2 diabetes mellitus | Glutamine (NPC197087) | NP level |
| NCT02282839 | Oral Glutamine and Mucositis of Head and Neck Cancer Patients Undergoing Radiation | mucositis | Glutamine (NPC197087) | NP level |
| NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients | prostate cancer | Rutin (NPC176740) | NP level |
| NCT01087658 | Oral Glutamine in the Prevention of Oxaliplatin-induced Neurotoxicity | colorectal neoplasm | Glutamine (NPC197087) | NP level |
| NCT00005775 | Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants | fetal growth restriction;premature birth;Sepsis | Glutamine (NPC197087) | NP level |
| NCT00006994 | S9908: Glutamine in Treating Mucositis Caused by Radiation Therapy in Patients With Newly Diagnosed Cancer of the Mouth or Throat | oral mucositis | Glutamine (NPC197087) | NP level |
| NCT00133406 | Long-term Impact and Intervention for Diarrhea in Brazil | diarrheal disease | Glutamine (NPC197087) | NP level |
| NCT00003898 | Glutamine in Treating Side Effects in Children Who Are Undergoing Stem Cell Transplantation | neoplasm | Glutamine (NPC197087) | NP level |
| NCT00133978 | Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients | Multiple Organ Failure;Sepsis | Glutamine (NPC197087) | NP level |
| NCT00003170 | Glutamine in Preventing Acute Diarrhea in Patients With Pelvic Cancer | cancer | Glutamine (NPC197087) | NP level |
| NCT01534663 | Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure | heart failure | Glutamine (NPC197087) | NP level |
| NCT00018109 | A Multicenter Randomized Placebo-Controlled Double-Blind Study to Assess Efficacy and Safety of Glutamine and Creatine Monohydrate in Duchenne Muscular Dystrophy (DMD) | Duchenne muscular dystrophy | Glutamine (NPC197087) | NP level |
| NCT01353638 | Safety and Efficacy of the Addition of Alanyl-Glutamine-Dipeptide to Dialysis Solution in Peritoneal Dialysis | chronic kidney disease | Glutamine (NPC197087) | NP level |
| NCT04684381 | Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease Patients | sickle cell anemia | Glutamine (NPC197087) | NP level |
| NCT05371184 | Glutamine Role in Preventing Vaso-occlusive Crisis Among SCD Patients | sickle cell anemia | Glutamine (NPC197087) | NP level |
| NCT02012608 | Glutamine for the Prevention of Radiation Toxicity in Subjects Conserving Therapy | breast cancer | Glutamine (NPC197087) | NP level |
| NCT00131508 | Trial of Oral Glutamine in Patients With Sickle Cell Anemia | sickle cell anemia | Glutamine (NPC197087) | NP level |
| NCT01263041 | Effect of L-arginine and Glutamine on Preterm | Sepsis | Glutamine (NPC197087) | NP level |
| NCT00010634 | Complementary Naturopathic Medicine for Periodontitis | periodontitis | Glutamine (NPC197087) | NP level |
| NCT04909905 | Glutamine Supplementation and Short-term Mortality in Covid-19 | COVID-19 | Glutamine (NPC197087) | NP level |
| NCT00455247 | Efficacy of an Oral Formula in Prevention of Anti-cancer Therapy Side Effects | cancer | Glutamine (NPC197087) | NP level |
| NCT00016653 | Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy | Duchenne muscular dystrophy | Glutamine (NPC197087) | NP level |
| NCT04634539 | Trial of First-line L-glutamine With Gemcitabine and Nab-paclitaxel in Advanced Pancreatic Cancer | pancreatic ductal adenocarcinoma | Glutamine (NPC197087) | NP level |
| NCT02701673 | Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed Lymphoma | lymphoma | Glutamine (NPC197087) | NP level |
| NCT02114502 | Carfilzomib/SAHA Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant in Myeloma | multiple myeloma | Glutamine (NPC197087) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CSNK2A1,TDP1,FUT7,ESR1,PGD,ELAVL3,PSMB5
|
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT04684381,NCT00125788,NCT01179217,NCT00586209,NCT05371184,NCT00131508
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
TDP1,HSD17B10,FUT7,PGD,ELAVL3,PSMB5
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
ACHE,BCL2,FUT7,BLM,ELAVL3
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
LMNA,CSNK2A1,BCL2,BLM,ELAVL3
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
LMNA,ACHE,FUT7,BLM,PGD
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
LMNA,TDP1,CSNK2A2,FUT7,PGD
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B10,PSMB1,ACHE,FUT7,PSMB5
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
RAD52,ACHE,FUT7,BLM,PGD
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
BCL2,ESR1
NCT01705652,NCT01607879 |
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT01263041,NCT00395161,NCT00005775,NCT00133978
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
NCT02961816,NCT02701673,NCT02589145,NCT01983969
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00003170,NCT01983969,NCT01952847,NCT00455247
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
ELAVL3,ESR1,BLM,FUT7
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
BCL2,CSNK2A1,ESR1
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
ESR1,BCL2
NCT02012608 |
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT00016653,NCT00296621,NCT00018109
|
Polyneuropathy, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
NCT00195013,NCT02024191,NCT02215083
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ACHE,KDM4E,ELAVL3
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
ESR1
NCT02351323 |
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1,PGD
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
BCL2
NCT02114502 |
Oral mucositisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01 |
NCT02282839,NCT00006994
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NCT03947879,NCT00673894
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT00133562,NCT00338221
|
ThalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50 |
NCT00586209,NCT00125788
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
BLM,FUT7
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ACHE,FUT7
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
BLM,PGD
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
BCL2,FUT7
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
LMNA,ACHE
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ACHE,BLM
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
ACHE,BLM
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
PGD,BLM
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
LMNA,BLM
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
ESR1,FUT7
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
BLM,FUT7
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
LMNA,TDP1,CSNK2A1,HSD17B10,PSMB1,ACHE,BCL2,CSNK2A2,BLM,PSMB5
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
BCL2
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
ACHE
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
ESR1
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
BCL2
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
BCL2
|
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
BCL2
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
ESR1
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ACHE
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
ESR1
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
ACHE
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
BCL2
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ACHE
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
BCL2
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
BCL2
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
BCL2
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
BCL2
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
BCL2
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
BCL2
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
BCL2
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
ESR1
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
ESR1
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
BCL2
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ESR1
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
BCL2
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
CSNK2A1
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1
|
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
BCL2
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
BCL2
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
ACHE
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ESR1
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
BCL2
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
BCL2
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT01353638
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT00003898
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NCT04019769
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT01478126
|
NosocomialDisease Category: X.Extension CodesDisease ICD-11 Code: XB25 |
NCT01704430
|
Classical organic aciduriaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.E0 |
NCT00645879
|
Periodontal diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0C |
NCT00010634
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NCT01414244
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
NCT01250782
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
NCT00838149
|
Multi organ failureDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG4A |
NCT00133978
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT01051999
|
Preterm newborn, unspecifiedDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA21.4Z |
NCT00005775
|
Clostridium difficile enterocolitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A04 |
NCT02053350
|
Generalised anxiety disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B00 |
NCT04274114
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
NCT01534663
|
Infectious gastroenteritis or colitis without specification of infectious agentDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A40.Z |
NCT00133406
|
Intrauterine growth restriction, unspecifiedDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA20.1Z |
NCT00005775
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04909905
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
NCT01087658
|
AdenocarcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D40 |
NCT04634539
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
BLM
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
BLM
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ACHE
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
BLM
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
BLM
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ACHE
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FUT7
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
ACHE
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
BLM
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
