Collective Molecular Activities of the Plant: Cissus Pallidiflorus
Plant ID: NPO20546
Plant Latin Name: Cissus Pallidiflorus
Taxonomy Genus: Cissus
Taxonomy Family: Vitaceae
Plant External Links:
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
81 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
30 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
20 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC90841
Ingredient ID: NPC86496
Ingredient ID: NPC78159
Ingredient ID: NPC74910
Ingredient ID: NPC71283
Ingredient ID: NPC65840
Ingredient ID: NPC62049
Ingredient ID: NPC59650
Ingredient ID: NPC51939
Ingredient ID: NPC48057
Ingredient ID: NPC46864
Ingredient ID: NPC41029
Ingredient ID: NPC40592
Ingredient ID: NPC39822
Ingredient ID: NPC37623
Ingredient ID: NPC34808
Ingredient ID: NPC31991
Ingredient ID: NPC31494
Ingredient ID: NPC307792
Ingredient ID: NPC307131
Ingredient ID: NPC301470
Ingredient ID: NPC300059
Ingredient ID: NPC299475
Ingredient ID: NPC297581
Ingredient ID: NPC29224
Ingredient ID: NPC278153
Ingredient ID: NPC265662
Ingredient ID: NPC261153
Ingredient ID: NPC259688
Ingredient ID: NPC257668
Ingredient ID: NPC257640
Ingredient ID: NPC257194
Ingredient ID: NPC256892
Ingredient ID: NPC249967
Ingredient ID: NPC244543
Ingredient ID: NPC242930
Ingredient ID: NPC242428
Ingredient ID: NPC241279
Ingredient ID: NPC235080
Ingredient ID: NPC233832
Ingredient ID: NPC228039
Ingredient ID: NPC226453
Ingredient ID: NPC223059
Ingredient ID: NPC222618
Ingredient ID: NPC22228
Ingredient ID: NPC219397
Ingredient ID: NPC216199
Ingredient ID: NPC208949
Ingredient ID: NPC208573
Ingredient ID: NPC206510
Ingredient ID: NPC205926
Ingredient ID: NPC200061
Ingredient ID: NPC194883
Ingredient ID: NPC18928
Ingredient ID: NPC189079
Ingredient ID: NPC187648
Ingredient ID: NPC18603
Ingredient ID: NPC183927
Ingredient ID: NPC182238
Ingredient ID: NPC178212
Ingredient ID: NPC17810
Ingredient ID: NPC178085
Ingredient ID: NPC174146
Ingredient ID: NPC170427
Ingredient ID: NPC15636
Ingredient ID: NPC154213
Ingredient ID: NPC153923
Ingredient ID: NPC147092
Ingredient ID: NPC146795
Ingredient ID: NPC143726
Ingredient ID: NPC133609
Ingredient ID: NPC131486
Ingredient ID: NPC129226
Ingredient ID: NPC128828
Ingredient ID: NPC127508
Ingredient ID: NPC124598
Ingredient ID: NPC122752
Ingredient ID: NPC114685
Ingredient ID: NPC110406
Ingredient ID: NPC103518
Ingredient ID: NPC103483
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Therapeutic Target | Enzyme | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
| Therapeutic Target | Peptide receptor (family A GPCR) | TSHR | Thyroid stimulating hormone receptor | P16473 | CHEMBL1963 |
| Drug Transporter | SLC superfamily of solute carriers | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Q9Y6L6 | CHEMBL1697668 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | CNR1 | Cannabinoid CB1 receptor | P21554 | CHEMBL218 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | CNR2 | Cannabinoid CB2 receptor | P34972 | CHEMBL253 |
| Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
| Therapeutic Target | Transient receptor potential channel | TRPV1 | Vanilloid receptor | Q8NER1 | CHEMBL4794 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 64 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT00005107 | Role of Nitric Oxide in Cirrhosis: Relationship With Systemic Hemodynamics, Renal Function, Vasoactive Systems and Endotoxemia | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT05470998 | L-Arginine in Children Having Sickle Cell Disease With Increased Tricuspid Regurgitant Jet Velocity | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT02017249 | Efficacy Study of Oral Arginine to Improve Immune Function in Glioblastoma Multiforme | glioblastoma multiforme | Arginine (NPC226453) | NP level |
| NCT04249336 | Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH | allergic disease | Arginine (NPC226453) | NP level |
| NCT00571766 | Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT01266018 | Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer | small cell lung carcinoma | Arginine (NPC226453) | NP level |
| NCT04750902 | A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children | dental caries | Arginine (NPC226453) | NP level |
| NCT00345150 | Effects of Inhibition of NO-Synthesis on Renal Hemodynamics and Sodium Excretion in Patients With Essential Hypertension and Healthy Controls | hypertension | Arginine (NPC226453) | NP level |
| NCT00223717 | Treatment of Supine Hypertension in Autonomic Failure | hypertension | Arginine (NPC226453) | NP level |
| NCT04874012 | Effect of Taurine on Glycemic, Lipid and Inflammatory Profile in Individuals With Type 2 Diabetes | type 2 diabetes mellitus | Taurine (NPC300059) | NP level |
| NCT00137124 | L-Arginine Metabolism in Essential Hypertension | essential hypertension | Arginine (NPC226453) | NP level |
| NCT00405665 | The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis | cystic fibrosis | Arginine (NPC226453) | NP level |
| NCT00616304 | Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT00391001 | Taurine in Adolescents With Bipolar Disorder | bipolar disorder | Taurine (NPC300059) | NP level |
| NCT05342272 | Comparison of Gum® HydralTM Moisturizing Gel and Biotene® Oral Gel in Dry Mouth Sensation Reduction | xerostomia | Taurine (NPC300059) | NP level |
| NCT02440061 | Ghrelin and Beta Cell Function in Diabetes | type 2 diabetes mellitus | Arginine (NPC226453) | NP level |
| NCT01388764 | Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT00280683 | Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma | asthma | Arginine (NPC226453) | NP level |
| NCT01796678 | Arginine Therapy in Sickle Cell Disease-VOC Clinical Trial | pain | Arginine (NPC226453) | NP level |
| NCT03640949 | Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest | sudden cardiac arrest | Arginine (NPC226453) | NP level |
| NCT01381354 | Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) | multiple sclerosis | Taurine (NPC300059) | NP level |
| NCT01192828 | Oxidative Stress Markers In Inherited Homocystinuria And The Impact Of Taurine | homocystinuria | Taurine (NPC300059) | NP level |
| NCT00157521 | L-Arginine in Pre-Eclampsia | preeclampsia | Arginine (NPC226453) | NP level |
| NCT00408577 | Prevention of Cardiac and Vascular Events in Patients With NGT/IGT. | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT01263041 | Effect of L-arginine and Glutamine on Preterm | Sepsis | Arginine (NPC226453) | NP level |
| NCT04631536 | Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC | COVID-19 | Arginine (NPC226453) | NP level |
| NCT01607879 | Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation | prostate cancer | Arginine (NPC226453) | NP level |
| NCT02447874 | Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT01287585 | Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy | hepatocellular carcinoma | Arginine (NPC226453) | NP level |
| NCT00974714 | L-arginine Effects on Chronic Hypertension in Pregnancy | preeclampsia | Arginine (NPC226453) | NP level |
| NCT04535427 | Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis | rheumatoid arthritis | Arginine (NPC226453) | NP level |
| NCT00275418 | Beta Carotene From Natural Source for Patients With Non-Active Crohn's Disease | Crohn's disease | Beta Carotene (NPC17810) | NP level |
| NCT03446456 | Vasopressin and Pain Perception in the Brain | pain | Arginine (NPC226453) | NP level |
| NCT02291458 | L-arginine and Brown Adipose Tissue | Glucose intolerance | Arginine (NPC226453) | NP level |
| NCT05042024 | Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis | periodontitis | Arginine (NPC226453) | NP level |
| NCT03580122 | The Effect of Arginine on Classic Galactosemia | classic galactosemia | Arginine (NPC226453) | NP level |
| NCT00200746 | Treatment of Alcohol-Related Hepatitis With Arginine | Hepatitis, Alcoholic | Arginine (NPC226453) | NP level |
| NCT04054973 | L-arginine Study for Persistent Symptoms of Schizophrenia | schizophrenia | Arginine (NPC226453) | NP level |
| NCT03861416 | "Unifuzol®" in Patients With Peripheral Arterial Disease | peripheral arterial disease | Arginine (NPC226453) | NP level |
| NCT00047983 | Omega-3 Fatty Acids That Affect the Immune System in Kidney Transplant Patients | kidney disease | Arginine (NPC226453) | NP level |
| NCT02516085 | Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin | Duchenne muscular dystrophy | Arginine (NPC226453) | NP level |
| NCT01816698 | Effects and Safety of Taurine Granule on Blood Pressure in Prehypertensive | hypertension | Taurine (NPC300059) | NP level |
| NCT01603446 | L-arginine Therapy on Endothelium-dependent Vasodilation & Mitochondrial Metabolism in MELAS Syndrome | MELAS | Arginine (NPC226453) | NP level |
| NCT00677339 | L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB) | pulmonary tuberculosis | Arginine (NPC226453) | NP level |
| NCT02388178 | To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Study | dental caries | Arginine (NPC226453) | NP level |
| NCT01142219 | L-Arginine and Sickle Cell Disease | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | myocardial infarction;Myocardial Ischemia | Beta Carotene (NPC17810) | NP level |
| NCT01324115 | NG-Nitro-L-Arginine in Treating Patients With Advanced Solid Tumors | neoplasm | Arginine (NPC226453) | NP level |
| NCT00513617 | Effectiveness of Arginine as a Treatment for Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT03088345 | Early Use of Vasopressin in Post-Fontan Management | congenital heart disease | Arginine (NPC226453) | NP level |
| NCT00217165 | Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study | bipolar disorder | Taurine (NPC300059) | NP level |
| NCT00056433 | Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia | sickle cell anemia | Arginine (NPC226453) | NP level |
| NCT00420823 | A Study of Taurine in Patients With First-episode Psychosis Receiving Antipsychotic Treatment | mental or behavioural disorder | Taurine (NPC300059) | NP level |
| NCT01439555 | Endothelial Facilitation in Alzheimer's Disease | Alzheimer disease | Arginine (NPC226453) | NP level |
| NCT00000161 | Randomized Trials of Vitamin Supplements and Eye Disease | cataract;macular degeneration | Beta Carotene (NPC17810) | NP level |
| NCT00134433 | Endothelial Modulation for Angiogenic Therapy | coronary artery disease | Arginine (NPC226453) | NP level |
| NCT00147368 | Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria | Plasmodium falciparum malaria | Arginine (NPC226453) | NP level |
| NCT00006136 | Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia | Beta-thalassemia | Arginine (NPC226453) | NP level |
| NCT00000152 | Randomized Trial of Beta-Carotene and Macular Degeneration | macular degeneration | Beta Carotene (NPC17810) | NP level |
| NCT03679780 | The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction | cardiovascular disease | Arginine (NPC226453) | NP level |
| NCT00344734 | Effects of Acute L-NMMA Treatment on Renal Hemodynamics and Vasoactive Hormones in Patients With Congestive Heart Failure | congestive heart failure | Arginine (NPC226453) | NP level |
| NCT00344916 | Phase 1 Study of L-NMMA in Patients With Liver Cirrhosis | cirrhosis of liver | Arginine (NPC226453) | NP level |
| NCT00917826 | Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies | lymphoma | Arginine (NPC226453) | NP level |
| NCT00345605 | Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder | argininosuccinic aciduria | Arginine (NPC226453) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
TRPV1,CNR2,CNR1
NCT03446456,NCT01796678 |
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT01142219,NCT00513617,NCT00056433,NCT05470998,NCT02447874
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
CNR1,NFKB1
NCT04874012,NCT02440061 |
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
BLM,CNR1,CNR2,TSHR
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
CNR2,NFKB1,TRPV1
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NFKB1,TRPV1
NCT04535427 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT00223717,NCT00345150,NCT01816698
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
NCT00571766,NCT00974714,NCT00157521
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
BLM,CNR2,TSHR
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
CNR1,CNR1,TSHR
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
BLM,SLCO1B1,TSHR
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
BLM,SLCO1B1,TSHR
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
BLM,CNR2,SLCO1B1
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
CNR2,CNR1
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CNR2,CNR1
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
TRPV1,CNR2
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
CNR2
NCT00275418 |
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
CNR1
NCT00047983 |
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NFKB1
NCT01381354 |
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
TRPV1
NCT00280683 |
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
NCT00147368,NCT00616304
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
NCT00391001,NCT00217165
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT00344916,NCT00005107
|
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT02516085,NCT01388764
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT00000161,NCT00000152
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
NCT03679780,NCT00408577
|
Dental cariesDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA08.0 |
NCT02388178,NCT04750902
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
BLM,CNR1
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
BLM,CNR1
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
BLM,SLCO1B1
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
BLM,CNR2
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CNR2,CNR1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
BLM,CNR1
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
BLM,SLCO1B1
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
BLM,SLCO1B1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CNR2,CNR1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
NFKB1,CNR2
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
BLM,CNR2
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
CNR2,CNR1
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
BLM,TSHR
|
Cannabis use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C41 |
CNR1
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
NFKB1
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NFKB1
|
Anorexia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B80 |
CNR1
|
Knee osteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
TRPV1
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
TRPV1
|
Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
CNR1
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
CNR1
|
Visual system diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9E1Z |
TRPV1
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
CNR2
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
TRPV1
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
TSHR
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
CNR1
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
CNR1
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
TRPV1
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NFKB1
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1
|
Lower limb mononeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C11 |
TRPV1
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
CNR1
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
NFKB1
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
CNR1
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
NFKB1
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
NFKB1
|
Functional bladder disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC50 |
TRPV1
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
TSHR
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
CNR1
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
NFKB1
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT01324115
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04631536
|
Disorders of methionine cycle or sulphur amino acid metabolismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.B |
NCT01192828
|
Cardiac arrestDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC82 |
NCT03640949
|
Periodontal diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0C |
NCT05042024
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
NCT04054973
|
Mental/behavioural/neurodevelopmental disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6E20-6E8Z |
NCT00420823
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT01263041
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT01287585
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
NCT00917826
|
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT00000541
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT00405665
|
Alcoholic hepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB94.1 |
NCT00200746
|
Beta thalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50.2 |
NCT00006136
|
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT02017249
|
Argininosuccinic aciduriaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50.A0 |
NCT00345605
|
Galactose-1-phosphate uridyltransferase deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C51.40 |
NCT03580122
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NCT04249336
|
Chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
NCT03861416
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
NCT01439555
|
MelasmaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60.1 |
NCT01603446
|
Small cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.1 |
NCT01266018
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT00134433
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT00000541
|
Other specified disorders of carbohydrate absorption or transportDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C61.Y |
NCT02291458
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
NCT01607879
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00344734
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
NCT00137124
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT03088345
|
Tuberculosis of the respiratory systemDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10 |
NCT00677339
|
XerostomiaDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA02.1 |
NCT05342272
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
NCT00000161
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
TSHR
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
TSHR
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
TSHR
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
BLM
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
TSHR
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
SLCO1B1
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
NFKB1
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
SLCO1B1
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
SLCO1B1
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
CNR1
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
BLM
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CNR1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
BLM
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
BLM
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
