CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Hosta Sieboldiana

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PLANiTS DNA barcode

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Taxonomic Information

Plant ID: NPO19672
Plant Latin Name: Hosta Sieboldiana
Taxonomy Genus: Hosta
Taxonomy Family: Asparagaceae

Plant External Links:

NCBI TaxonomyDB: 708432
Plant-of-the-World-Online: 536637-1

Used in Medicines

Country/Region:

China

Traditional Medicine System:

TCM

Geographical Distribution

Japan; China; South Africa

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

58 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

54 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)