Plant ID: NPO19620
Plant Latin Name: Stemona Tuberosa
Taxonomy Genus: Stemona
Taxonomy Family: Stemonaceae
NCBI TaxonomyDB:
167572
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC95787
Ingredient ID: NPC95666
Ingredient ID: NPC93569
Ingredient ID: NPC93074
Ingredient ID: NPC86352
Ingredient ID: NPC84117
Ingredient ID: NPC81853
Ingredient ID: NPC7705
Ingredient ID: NPC74447
Ingredient ID: NPC66706
Ingredient ID: NPC58281
Ingredient ID: NPC55823
Ingredient ID: NPC475067
Ingredient ID: NPC42813
Ingredient ID: NPC33670
Ingredient ID: NPC33270
Ingredient ID: NPC326410
Ingredient ID: NPC325389
Ingredient ID: NPC324971
Ingredient ID: NPC324235
Ingredient ID: NPC322032
Ingredient ID: NPC321803
Ingredient ID: NPC317434
Ingredient ID: NPC316885
Ingredient ID: NPC316475
Ingredient ID: NPC312380
Ingredient ID: NPC310181
Ingredient ID: NPC308122
Ingredient ID: NPC307165
Ingredient ID: NPC306232
Ingredient ID: NPC305463
Ingredient ID: NPC301950
Ingredient ID: NPC298328
Ingredient ID: NPC297796
Ingredient ID: NPC295217
Ingredient ID: NPC295089
Ingredient ID: NPC291428
Ingredient ID: NPC280141
Ingredient ID: NPC278525
Ingredient ID: NPC268667
Ingredient ID: NPC264375
Ingredient ID: NPC257885
Ingredient ID: NPC256154
Ingredient ID: NPC254793
Ingredient ID: NPC253747
Ingredient ID: NPC247643
Ingredient ID: NPC245787
Ingredient ID: NPC245375
Ingredient ID: NPC242580
Ingredient ID: NPC242520
Ingredient ID: NPC236709
Ingredient ID: NPC233948
Ingredient ID: NPC233274
Ingredient ID: NPC232440
Ingredient ID: NPC23018
Ingredient ID: NPC22885
Ingredient ID: NPC227360
Ingredient ID: NPC221186
Ingredient ID: NPC22098
Ingredient ID: NPC21990
Ingredient ID: NPC218267
Ingredient ID: NPC216252
Ingredient ID: NPC212223
Ingredient ID: NPC210192
Ingredient ID: NPC207326
Ingredient ID: NPC200321
Ingredient ID: NPC194750
Ingredient ID: NPC192306
Ingredient ID: NPC190514
Ingredient ID: NPC188658
Ingredient ID: NPC188169
Ingredient ID: NPC183870
Ingredient ID: NPC178952
Ingredient ID: NPC176066
Ingredient ID: NPC174463
Ingredient ID: NPC174167
Ingredient ID: NPC168316
Ingredient ID: NPC165792
Ingredient ID: NPC158663
Ingredient ID: NPC158020
Ingredient ID: NPC155674
Ingredient ID: NPC152440
Ingredient ID: NPC148597
Ingredient ID: NPC141344
Ingredient ID: NPC139406
Ingredient ID: NPC137374
Ingredient ID: NPC134260
Ingredient ID: NPC133089
Ingredient ID: NPC127026
Ingredient ID: NPC126836
Ingredient ID: NPC126759
Ingredient ID: NPC120981
Ingredient ID: NPC115067
Ingredient ID: NPC100340
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Transferase | GSTP1 | Glutathione S-transferase Pi | P09211 | CHEMBL3902 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 1 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT04649203 | Cytoflavin in the Treatment of Patients With Diabetic Polyneuropathy | diabetic neuropathy | Succinic Acid (NPC236709) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
LMNA,GSTP1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
LMNA,GSTP1
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
LMNA,GSTP1
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
LMNA,GSTP1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
LMNA,GSTP1
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
GSTP1
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
GSTP1
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
GSTP1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
GSTP1
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
GSTP1
|
Diabetic polyneuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C03.0 |
NCT04649203
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
GSTP1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
GSTP1
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
GSTP1
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
GSTP1
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
LMNA
|