Collective Molecular Activities of the Plant: Rosa Chinensis
Country/Region:
China; Indonesia; IndiaTraditional Medicine System:
Indian Folk; TCMMedicinal Functions:
Anodyne; Cancer; Women's complaints
Uzbekistan; Australia; South Africa; Laos; Indonesia; India; United States; Guatemala; Vietnam; China; Greece; Kazakhstan
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
73 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
38 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
42 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC94610
Ingredient ID: NPC88789
Ingredient ID: NPC8505
Ingredient ID: NPC81010
Ingredient ID: NPC7097
Ingredient ID: NPC68889
Ingredient ID: NPC62469
Ingredient ID: NPC61665
Ingredient ID: NPC54802
Ingredient ID: NPC51843
Ingredient ID: NPC47422
Ingredient ID: NPC43696
Ingredient ID: NPC36108
Ingredient ID: NPC32977
Ingredient ID: NPC328050
Ingredient ID: NPC324696
Ingredient ID: NPC32368
Ingredient ID: NPC320283
Ingredient ID: NPC320224
Ingredient ID: NPC319108
Ingredient ID: NPC318533
Ingredient ID: NPC317921
Ingredient ID: NPC317489
Ingredient ID: NPC315224
Ingredient ID: NPC306207
Ingredient ID: NPC302857
Ingredient ID: NPC300206
Ingredient ID: NPC29883
Ingredient ID: NPC294902
Ingredient ID: NPC288404
Ingredient ID: NPC281131
Ingredient ID: NPC275463
Ingredient ID: NPC270094
Ingredient ID: NPC268761
Ingredient ID: NPC257124
Ingredient ID: NPC227211
Ingredient ID: NPC225710
Ingredient ID: NPC21045
Ingredient ID: NPC20791
Ingredient ID: NPC204932
Ingredient ID: NPC197149
Ingredient ID: NPC194650
Ingredient ID: NPC190771
Ingredient ID: NPC182840
Ingredient ID: NPC181465
Ingredient ID: NPC179950
Ingredient ID: NPC178134
Ingredient ID: NPC174754
Ingredient ID: NPC173638
Ingredient ID: NPC173637
Ingredient ID: NPC172343
Ingredient ID: NPC171590
Ingredient ID: NPC167976
Ingredient ID: NPC16649
Ingredient ID: NPC165651
Ingredient ID: NPC164576
Ingredient ID: NPC15970
Ingredient ID: NPC156655
Ingredient ID: NPC141195
Ingredient ID: NPC137167
Ingredient ID: NPC135391
Ingredient ID: NPC135088
Ingredient ID: NPC133671
Ingredient ID: NPC1321
Ingredient ID: NPC127546
Ingredient ID: NPC123474
Ingredient ID: NPC116775
Ingredient ID: NPC112866
Ingredient ID: NPC111929
Ingredient ID: NPC108218
Ingredient ID: NPC107522
Ingredient ID: NPC1075
Ingredient ID: NPC100980
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
| Therapeutic Target | Enzyme | HPGD | 15-hydroxyprostaglandin dehydrogenase [NAD+] | P15428 | CHEMBL1293255 |
| Therapeutic Target | Enzyme | NOX4 | NADPH oxidase 4 | Q9NPH5 | CHEMBL1250375 |
| Therapeutic Target | Enzyme | RECQL | ATP-dependent DNA helicase Q1 | P46063 | CHEMBL1293236 |
| Therapeutic Target | Enzyme | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | P27695 | CHEMBL5619 |
| Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
| Therapeutic Target | Enzyme | ALOX12 | Arachidonate 12-lipoxygenase | P18054 | CHEMBL3687 |
| Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
| Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
| Therapeutic Target | Lyase | CA4 | Carbonic anhydrase IV | P22748 | CHEMBL3729 |
| Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
| Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
| Therapeutic Target | Lysine demethylase | KDM4E | Lysine-specific demethylase 4D-like | B2RXH2 | CHEMBL1293226 |
| Therapeutic Target | Metallo protease | MMP9 | Matrix metalloproteinase 9 | P14780 | CHEMBL321 |
| Therapeutic Target | Metallo protease | MMP2 | Matrix metalloproteinase-2 | P08253 | CHEMBL333 |
| Therapeutic Target | Metallo protease | MMP1 | Matrix metalloproteinase-1 | P03956 | CHEMBL332 |
| Therapeutic Target | Other cytosolic protein | HSPA1A | Heat shock 70 kDa protein 1 | P0DMV8 | CHEMBL5460 |
| Therapeutic Target | Oxidoreductase | AKR1B1 | Aldose reductase | P15121 | CHEMBL1900 |
| Therapeutic Target | Oxidoreductase | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | P37059 | CHEMBL2789 |
| Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
| Therapeutic Target | Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
| Therapeutic Target | Peptide receptor (family A GPCR) | TSHR | Thyroid stimulating hormone receptor | P16473 | CHEMBL1963 |
| Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
| Therapeutic Target | Protein Kinase | CSNK2A1 | Casein kinase II alpha | P68400 | CHEMBL3629 |
| Therapeutic Target | Protein Kinase | PIM1 | Serine/threonine-protein kinase PIM1 | P11309 | CHEMBL2147 |
| Therapeutic Target | Protein Kinase | AURKB | Serine/threonine-protein kinase Aurora-B | Q96GD4 | CHEMBL2185 |
| Therapeutic Target | Protein Kinase | AXL | Tyrosine-protein kinase receptor UFO | P30530 | CHEMBL4895 |
| Therapeutic Target | Protein Kinase | MET | Hepatocyte growth factor receptor | P08581 | CHEMBL3717 |
| Therapeutic Target | Protein Kinase | IGF1R | Insulin-like growth factor I receptor | P08069 | CHEMBL1957 |
| Therapeutic Target | Protein Kinase | NUAK1 | NUAK family SNF1-like kinase 1 | O60285 | CHEMBL5784 |
| Therapeutic Target | Protein Kinase | SRC | Tyrosine-protein kinase SRC | P12931 | CHEMBL267 |
| Therapeutic Target | Protein Kinase | EGFR | Epidermal growth factor receptor erbB1 | P00533 | CHEMBL203 |
| Therapeutic Target | Protein Kinase | KDR | Vascular endothelial growth factor receptor 2 | P35968 | CHEMBL279 |
| Therapeutic Target | Protein Kinase | YES1 | Tyrosine-protein kinase YES | P07947 | CHEMBL2073 |
| Therapeutic Target | Protein Kinase | INSR | Insulin receptor | P06213 | CHEMBL1981 |
| Therapeutic Target | Protein Kinase | FLT3 | Tyrosine-protein kinase receptor FLT3 | P36888 | CHEMBL1974 |
| Therapeutic Target | Protein Kinase | CDK1 | Cyclin-dependent kinase 1 | P06493 | CHEMBL308 |
| Therapeutic Target | Protein Kinase | TEK | Tyrosine-protein kinase TIE-2 | Q02763 | CHEMBL4128 |
| Drug Transporter | SLC superfamily of solute carriers | SLC22A6 | Solute carrier family 22 member 6 | Q4U2R8 | CHEMBL1641347 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | DRD1 | Dopamine D1 receptor | P21728 | CHEMBL2056 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | GPR35 | G-protein coupled receptor 35 | Q9HC97 | CHEMBL1293267 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Transcription factor | SMAD3 | Mothers against decapentaplegic homolog 3 | P84022 | CHEMBL1293258 |
| Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
| Therapeutic Target | Transcription factor | AHR | Aryl hydrocarbon receptor | P35869 | CHEMBL3201 |
| Therapeutic Target | Transferase | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Q11130 | CHEMBL3596077 |
| Therapeutic Target | Transferase | POLH | DNA polymerase eta | Q9Y253 | CHEMBL5542 |
| Therapeutic Target | Transferase | POLI | DNA polymerase iota | Q9UNA4 | CHEMBL5391 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 41 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT04853199 | Quercetin In The Treatment Of SARS-COV 2 | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT01839344 | Effects of Quercetin on Blood Sugar and Blood Vessel Function in Type 2 Diabetes. | type 2 diabetes mellitus | Quercetin (NPC20791) | NP level |
| NCT04622865 | Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19 | COVID-19 | Isoquercetin (NPC179950) | NP level |
| NCT01348204 | Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators | cystic fibrosis | Quercetin (NPC20791) | NP level |
| NCT04733651 | Study to Investigate the Clinical Efficacy of Isoquercetin in Patients With COVID-19 | COVID-19 | Isoquercetin (NPC179950) | NP level |
| NCT01720147 | Quercetin in Children With Fanconi Anemia; a Pilot Study | Fanconi anemia | Quercetin (NPC20791) | NP level |
| NCT05062486 | A Study to Evaluate the Safety and Efficacy of RQC for AMD | age-related macular degeneration | Quercetin (NPC20791) | NP level |
| NCT04733534 | An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer | childhood cancer | Quercetin (NPC20791) | NP level |
| NCT01438320 | Q-Trial in Patients With Hepatitis C | chronic hepatitis C virus infection | Quercetin (NPC20791) | NP level |
| NCT02245204 | Phase I Studies of Chlorogenic Acid for Injection for Tolerance and Pharmacokinetic of Advanced Cancers | cancer | Chlorogenic Acid (NPC302857) | NP level |
| NCT02621060 | Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance | abnormal glucose tolerance | Chlorogenic Acid (NPC302857) | NP level |
| NCT02136342 | Phase 1 Trial of Chlorogenic Acid in Patients With Advanced Cancer | cancer | Chlorogenic Acid (NPC302857) | NP level |
| NCT04536090 | Study of Isoquercetin (IQC-950AN) Plus Standard of Care Versus Standard of Care Only for the Treatment of COVID-19 | COVID-19 | Isoquercetin (NPC179950) | NP level |
| NCT02226484 | Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? | gastroesophageal reflux disease | Quercetin (NPC20791) | NP level |
| NCT05422885 | Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease | aging | Quercetin (NPC20791) | NP level |
| NCT01375101 | Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus | oral lichen planus | Quercetin (NPC20791) | NP level |
| NCT01989897 | Effect of HSA or Saline Diluent on Immunotherapy Extract Stability as Determined by Graded ID Skin Tests | allergic rhinitis | Phenol (NPC100980) | NP level |
| NCT05456022 | Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line | mouth neoplasm | Quercetin (NPC20791) | NP level |
| NCT00966836 | Prevention of Transplant Atherosclerosis With Everolimus and Anti-cytomegalovirus Therapy | cytomegalovirus infection | Phenol (NPC100980) | NP level |
| NCT02446795 | Isoquercetin as an Adjunct Therapy in Patients With Kidney Cancer Receiving First-line Sunitinib: a Phase I/II Trial | renal cell carcinoma | Isoquercetin (NPC179950) | NP level |
| NCT01468415 | Efficiency Comparison Between Methylprednisolone and Phenol 8% Treatment Using a Trans Sacral Approach - on Lower Back Pain and Limbs | Back pain | Phenol (NPC100980) | NP level |
| NCT03751592 | Phase Ib/IIa Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Advanced Lung Cancer | lung cancer | Chlorogenic Acid (NPC302857) | NP level |
| NCT04907253 | Quercetin in Coronary Artery By-pass Surgery | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT02552888 | Nitrite, Isoquercetin and Endothelial Dysfunction (NICE) Trial | chronic kidney disease | Isoquercetin (NPC179950) | NP level |
| NCT04474626 | Isoquercetin in Sickle Cell Anemia | sickle cell anemia | Isoquercetin (NPC179950) | NP level |
| NCT03758014 | Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Grade IV GBM Patients | glioblastoma multiforme | Chlorogenic Acid (NPC302857) | NP level |
| NCT05276895 | Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis | osteoarthritis | Quercetin (NPC20791) | NP level |
| NCT04851821 | The Effectiveness of Phytotherapy in SARS-COV2(COVID-19) | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT04011618 | Effect of Ellagic Ácid on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion | metabolic syndrome | Ellagic Acid (NPC178134) | NP level |
| NCT04946383 | Safety and Effectivness of Quercetin & Dasatinib on Epigenetic Aging | aging | Quercetin (NPC20791) | NP level |
| NCT03943459 | Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT02728349 | Tolerance and Pharmacokinetic Study of Chlorogenic Acid to Advanced Glioblastoma | glioblastoma multiforme | Chlorogenic Acid (NPC302857) | NP level |
| NCT04514510 | Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease | sickle cell anemia | Isoquercetin (NPC179950) | NP level |
| NCT02848131 | Senescence in Chronic Kidney Disease | chronic kidney disease | Quercetin (NPC20791) | NP level |
| NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Quercetin (NPC20791);Ellagic Acid (NPC178134) | NP level |
| NCT01912820 | Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery | prostate adenocarcinoma | Quercetin (NPC20791) | NP level |
| NCT03989271 | Biological Effects of Quercetin in COPD | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT01708278 | Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT04648917 | GASC1 Inhibitor Caffeic Acid for Squamous Esophageal Cell Cancer (ESCC) | esophageal cancer | Caffeic Acid (NPC294902) | NP level |
| NCT01197040 | Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome | nephrotic syndrome | Phenol (NPC100980) | NP level |
| NCT02351622 | Caffeic Acid Tablets as a Second-line Therapy for ITP | autoimmune thrombocytopenic purpura | Caffeic Acid (NPC294902) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
TSHR,NOX4,FLT3,FUT7,DPP4,MMP9,MMP2,MMP1,AKR1B1
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
AURKB,ACHE,NOX4,NPSR1,CDK1,HSPA1A,ALOX15,MMP9,MMP1
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CA7,CYP1B1,NOX4,CA12,MET,ALOX5,DPP4,XDH,MMP1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
KDR,MMP2,EGFR,TP53,MET,MMP9,SRC,MMP1
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
AURKB,TP53,AXL,SRC,NFKB1,KDM1A,PIM1,FLT3
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
AHR,AXL,MTOR,SRC,INSR,FLT3,IGF1R,KDR
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
CDK1,DPP4,KDM1A,TP53,SRC,FLT3,MTOR,AURKB
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
AURKB,CYP1A2,CDK1,CYP2C9,CA2,MMP9,MMP1,AKR1B1
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
EGFR,TP53,MET,HSPA1A,KDR,MMP9,HSPA1B
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
KDR,MET,MMP9,MTOR,EGFR,MMP2
NCT02446795 |
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
TP53,EGFR,MTOR,SRC,MMP1,IGF1R,MMP2
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ABCG2,MMP1,CA2,AKR1B1,NFKB1,MMP9,ALOX5
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
ACHE,CA4,SRC,INSR,DPP4,CA2,LMNA
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
EGFR,GPR35,AXL,MMP2,CYP19A1,XDH,LMNA
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
ELAVL3,AURKB,CA12,FUT7,CDK1,MMP9,MMP1
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ALOX5,INSR,AKR1B1,ACHE,MTOR,IGF1R
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
AHR,TP53,KDR,EGFR,AXL,KDM1A
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
TP53,KDR,MET,EGFR,IGF1R,FLT3
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
EGFR,MTOR,KDR,MET,CSNK2A1,IGF1R
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ACHE,NFKB1,AXL,MET,DPP4,CYP19A1
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
TYR,NOX4,MET,NPSR1,CYP1A1,MMP1
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
AURKB,CA12,CDK1,MMP9,XDH,MMP1
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
AURKB,CA12,CYP1A2,MET,CYP1A1,CA2
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
CYP1B1,NOX4,FUT7,DPP4,SMAD3,MMP2
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
CA2,CA4,AKR1B1,MET,ACHE
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
KDR,TP53,MTOR,EGFR,MET
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
DPP4,NFKB1,AHR,FLT3,ALOX5
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
MET,FLT3,KDR,TP53,SRC
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
MET,KDR,ACHE,FLT3,INSR
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
AURKB,DPP4,INSR,KDR,AKR1B1
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04622865,NCT04536090,NCT04851821,NCT04733651,NCT04853199
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12,CDK1,MMP9,HSD17B2,MMP2
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
AURKB,NOX4,NPSR1,MMP9,MMP1
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
TP53,MET,DPP4,TEK
|
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
FLT3,SRC,KDR,TP53
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
TP53,EGFR,SRC,AXL
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
EGFR,KDR,MET,TYR
|
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
IGF1R,SRC,HSPA1A,HSPA1B
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
MET,EGFR,KDR,MTOR
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
IGF1R,XDH
NCT02552888,NCT02848131 |
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA2,CA12,CA4,CYP2C9
|
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
KDR,HSPA1A,HSPA1B,SRC
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
HSPA1A,AKR1B1,HSPA1B,CYP19A1
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
MTOR,MET,SRC,KDR
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
INSR,DPP4,NFKB1
NCT01839344 |
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
SRC,FLT3,TEK,KDM1A
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
FLT3,HSPA1B,SRC,HSPA1A
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
INSR,MMP9
MMP9,MMP1 |
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NOX4,FUT7,IGF1R,ABCG2
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ACHE,YES1,CYP1A1,MMP9
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
GPR35,AXL,FLT3,MET
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
AXL,HSD17B2,MET,ACHE
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CA7,GALNT2,SRC,DPP4,XDH,DRD1,HSD17B2,RECQL,AHR,EGFR,AURKB,CSNK2A2,CDK1,MMP9,POLH,MMP1,APEX1,MET,FLT3,ALOX15,PIM1,TYR,CA12,AXL,FUT7,ALOX5,HPGD,TDP1,KDR,LMNA
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
HSPA1B,SMAD3,HSPA1A
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NFKB1,AHR,ALOX5
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
EGFR,ALOX5,CDK1
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
IGF1R,TEK,APEX1
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SRC,DRD1,ACHE
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
TP53,MTOR,SRC
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
KDR,TSHR,MET
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2,CA12,CA4
|
Metastatic malignant neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E09 |
HSPA1A,AXL,HSPA1B
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
KDM1A,EGFR,MTOR
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
FLT3,TEK,CDK1
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
FLT3,KDR,EGFR
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MET,KDR,EGFR
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
EGFR,HSPA1B,HSPA1A
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
INSR,DPP4,NFKB1
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
AHR,ALOX5,KDR
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
SRC,KDR,MET
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
NOX4,ALOX15
NCT01912820 |
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT04733534,NCT02136342,NCT02245204
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
TSHR,CYP1A1,CDK1
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
TSHR,PIM1,CYP2C9
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
MMP9,NOX4,MMP1
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
SMAD3,AXL,ACHE
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CYP1A1,MMP9,MMP1
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FUT7,HPGD,POLH
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
NOX4,MMP9,AHR
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
KDR,ALOX5,XDH,MMP9,AHR,CA2,SRC,FLT3,KDM1A,MET,HSPA1B,CA4,CA12,TEK,AURKB,NFKB1,MTOR,CDK1,AXL,EGFR,CSNK2A1,YES1,HSPA1A,TP53,IGF1R,APEX1,POLB,PIM1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
CSNK2A1,ACHE,CISD1,SRC,TP53,RECQL,AHR,TEK,EGFR,AURKB,CSNK2A2,HSD17B10,CDK1,POLH,MMP1,APEX1,NUAK1,NOX4,MET,KDM1A,MMP2,CA12,AXL,TDP1,KDR,TSHR,LMNA,AKR1B1
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
ACHE,CA7,CISD1,POLB,DPP4,CA2,XDH,DRD1,HSD17B2,RECQL,TEK,AURKB,CYP1B1,CYP2C9,MMP1,NUAK1,MET,ALOX15,MMP2,PIM1,ABCG2,AXL,FUT7,NPSR1,ALOX5,LMNA
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ACHE,ALOX12,DPP4,XDH,DRD1,HSD17B2,AHR,TEK,CA4,CDK1,CYP2C9,SMAD3,MMP1,NUAK1,SLC22A6,NOX4,MET,ABCG2,CA12,FUT7,NPSR1,ALOX5,HPGD,KDR,MMP2,AKR1B1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CSNK2A1,CISD1,ALOX12,TP53,CA2,XDH,HSD17B2,AHR,ELAVL3,MMP9,POLH,MMP1,APEX1,NOX4,MET,YES1,ALOX15,CSNK2A3,CA12,CYP1A2,FUT7,ALOX5,HPGD,TDP1,TSHR
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
CA7,CISD1,GALNT2,POLB,TP53,CA2,DPP4,XDH,HSD17B2,ELAVL3,AURKB,HSD17B10,MMP9,MMP1,MET,YES1,CYP19A1,KDM1A,ALOX15,FUT7,NPSR1,TDP1,TSHR,AKR1B1
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
CSNK2A1,ALOX12,SRC,TP53,ELAVL3,CA4,AURKB,CDK1,MMP9,SMAD3,MMP1,NUAK1,GPR35,NOX4,MMP2,CSNK2A3,ALOX5,IGF1R,LMNA,AKR1B1
|
NADisease Category: NADisease ICD-11 Code: NA |
NOX4,MET
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
MTOR,EGFR
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
DRD1,INSR
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
ALOX5,SRC
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
TP53,MTOR
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
DRD1,AKR1B1
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
ALOX5,CA4
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
SRC,TP53
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
ACHE,DRD1
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
SRC,EGFR
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1,ABCG2
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
MET,EGFR
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
FLT3,MTOR
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
SRC,NFKB1
|
Gastrointestinal stromal tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5B |
KDR,SRC
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4
NCT04011618 |
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
ALOX5,XDH
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
XDH,CA2
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
TP53,MTOR
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TP53
NCT04648917 |
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
AURKB,MTOR
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
DRD1,MTOR
|
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
SRC,TP53
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
ALOX5,NFKB1
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
IGF1R,ALOX5
|
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
FLT3,ALOX5
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT03989271,NCT01708278
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT05422885,NCT04946383
|
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT03758014,NCT02728349
|
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT04514510,NCT04474626
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT03943459,NCT04907253
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
ABCG2,AURKB
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
HPGD,CYP1A1
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
CA4,ABCG2
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
MMP9,DPP4
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
NOX4,MMP1
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1,ABCG2
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
MMP9,MET
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
AURKB,CA4,SLC22A6,GPR35,NOX4,CA12,CDK1,CYP19A1,MMP9,MMP1,AURKB,CA12,SRC,CDK1,CYP19A1,MMP9,MMP1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
ACHE,CISD1,NFKB1,GALNT2,DPP4,DRD1,HSD17B2,CYP1B1,HSD17B10,CYP2C9,MMP9,APEX1,FLT3,ALOX15,FUT7,HPGD,AKR1B1
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ACHE,XDH,AURKB,CYP2C9,MMP9,MET,CYP19A1,TYR,ALOX5,AURKB,GPR35,FUT7,ALOX5,MMP9,TSHR,MMP1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MTOR,AXL,MMP9,MET,FLT3,KDM1A,MMP2,KDR,IGF1R,CDK1,EGFR,ALOX5,MMP1
NCT03751592 |
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
SRC,CA4,AURKB,CDK1,MMP9,MMP1,NUAK1,GPR35,NOX4,CYP19A1,CA12,IGF1R,MMP2,AKR1B1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
CA4,AURKB,CA7,NOX4,CA12,MET,FUT7,DPP4,HPGD,CDK1,CYP19A1,MMP9,HSD17B2,MMP1
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CDK1,IGF1R,KDR,CA12,TEK,SRC,CA2,EGFR,MTOR,CA4,MET,CYP19A1,AXL
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
ACHE,CA7,XDH,AURKB,CDK1,CYP2C9,MMP9,MMP1,GPR35,CA12,NPSR1,TSHR
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
CYP1A1,CA2,XDH,HSD17B2,AURKB,CDK1,CYP2C9,MMP9,MMP1,GPR35,ALOX15,NPSR1
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CA7,ALOX12,XDH,AURKB,CDK1,CYP2C9,MMP9,MMP1,CA12,NPSR1,TSHR
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
DPP4,CA2,CYP1B1,POLH,MET,CYP19A1,CSNK2A3,CA12,KDR,TSHR,LMNA
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
ELAVL3,ACHE,CA4,NOX4,MET,FUT7,CA2,MMP9,XDH,MMP1
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
DRD1,AURKB,CDK1,MMP9,MMP1,NOX4,MET,CYP19A1,ALOX15,NPSR1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ELAVL3,ACHE,GPR35,HPGD,CYP1A1,CA2,CYP2C9,ALOX15,MMP9,KDM4E
|
Metastatic digestive system neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D8Y |
SRC
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Synovial sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5A |
SRC
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
FLT3
|
Phakomatoses/hamartoneoplastic syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2D |
FLT3
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
DPP4
|
Extraocular muscle disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C82 |
IGF1R
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
TP53
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
Type-1/2 diabeteDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10-5A11 |
INSR
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
NFKB1
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
MET
|
Multiple structural anomalies syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F |
IGF1R
|
MastocytosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21 |
FLT3
|
LymphangioleiomyomatosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB07 |
MTOR
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
TP53
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
CYP19A1
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB9Z |
MET
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
FLT3
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NFKB1
|
FilariasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F66 |
ALOX5
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
XDH
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
MMP2
|
Mineral deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5K |
XDH
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
TYR
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR
|
Ocular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D00-2D07 |
APEX1
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
HydrocephalusDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D64 |
MTOR
|
Lysosomal diseaseDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C56 |
INSR
|
Digestive organ benign neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E92 |
KDR
|
Pleural mesotheliomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26 |
MTOR
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
SRC
|
Tic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A05 |
DRD1
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
DRD1
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
MMP2
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
EGFR
|
Ureteral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C92 |
AHR
|
Lip/oral cavity/pharynx neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6E |
TP53
|
Carcinoid syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B10 |
ALOX5
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
MMP9
|
Metastatic liver/bile duct neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D80 |
TP53
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
MMP9
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AKR1B1
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
FLT3
|
Human immunodeficiency virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C60-1C62 |
FLT3
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
CYP19A1
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
MET
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
TSHR
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
DRD1
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
Acquired hypermelanosisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60 |
TYR
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2
|
EncephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E47 |
XDH
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE
|
Bone/articular cartilage neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7B |
FLT3
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
|
Epidermal dysplasiasDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK90 |
SRC
|
LeiomyosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B58 |
SRC
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
AbortionDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA00 |
DRD1
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE
|
Transplanted organ/tissueDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QB63 |
FLT3
|
Inborn purine/pyrimidine/nucleotide metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C55 |
XDH
|
Ewing sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B52 |
KDM1A
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
TP53
|
Arteries/arterioles disorderDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD52 |
MTOR
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
IGF1R
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT05276895
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT01348204
|
Immune thrombocytopenic purpuraDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64.10 |
NCT02351622
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
NCT01989897
|
Spinal painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84 |
NCT01468415
|
Congenital cytomegalovirus infectionDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KA62.3 |
NCT00966836
|
Malignant neoplasms of other or unspecified parts of mouthDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B66 |
NCT05456022
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT01438320
|
Gastro-oesophageal reflux diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA22 |
NCT02226484
|
Impaired glucose toleranceDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.1 |
NCT02621060
|
Congenital aplastic anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A70.0 |
NCT01720147
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT05062486
|
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
NCT00455416
|
Lichen planusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA91 |
NCT01375101
|
Nephritic syndromeDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB40 |
NCT01197040
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
MMP9
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
CA4
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
CA4
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
MMP9
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
