Plant ID: NPO17862
Plant Latin Name: Zanthoxylum Planispinum
Taxonomy Genus: Zanthoxylum
Taxonomy Family: Rutaceae
NCBI TaxonomyDB:
1196222
Plant-of-the-World-Online:
n.a.
Unknown.
Ingredient ID: NPC73199
Ingredient ID: NPC70872
Ingredient ID: NPC57739
Ingredient ID: NPC49536
Ingredient ID: NPC42403
Ingredient ID: NPC4025
Ingredient ID: NPC37733
Ingredient ID: NPC35883
Ingredient ID: NPC34973
Ingredient ID: NPC34770
Ingredient ID: NPC296663
Ingredient ID: NPC276861
Ingredient ID: NPC269367
Ingredient ID: NPC268574
Ingredient ID: NPC235076
Ingredient ID: NPC232206
Ingredient ID: NPC197467
Ingredient ID: NPC179694
Ingredient ID: NPC154351
Ingredient ID: NPC146792
Ingredient ID: NPC146319
Ingredient ID: NPC144205
Ingredient ID: NPC141080
Ingredient ID: NPC138925
Ingredient ID: NPC131885
Ingredient ID: NPC118121
Ingredient ID: NPC105137
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
Therapeutic Target | Transient receptor potential channel | TRPA1 | Transient receptor potential cation channel subfamily A member 1 | O75762 | CHEMBL6007 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials |
---|
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
TRPA1,TRPA1
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
TRPA1
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
TRPA1
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
TRPA1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CYP1A2
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
TRPA1
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
TRPA1
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
TRPA1
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
TRPA1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
TRPA1
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
TRPA1
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
TRPA1
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
TRPA1
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
TRPA1
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CYP1A2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
TRPA1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
TRPA1
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
TRPA1
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP1A2
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
TRPA1
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
TRPA1
|